Grants for Public and State controlled institutions of higher education - Health

This funding opportunity provides financial support to higher education institutions and nonprofits to establish or renew research centers focused on advancing studies related to Alzheimer's disease and related dementias, promoting collaboration, innovation, and diversity in research efforts.

This grant provides $100,000 to public or nonprofit organizations in Arizona to create partnerships that connect community health workers with clinical settings to combat chronic diseases in underserved communities.

This funding opportunity provides financial support to researchers with active NIH grants to quickly adapt their projects to address urgent public health crises that have emerged unexpectedly.

This funding opportunity supports short-term research projects that explore the ethical challenges arising from advancements in neurotechnology and brain science, encouraging collaboration between ethicists and neuroscientists.

The overall goal of the Fogarty International Center (FIC) HIV Research Training Program is to strengthen the scientific capacity of institutions in low- and middle-income countries (LMICs) to conduct HIV research on the evolving HIV epidemic in their countries.This FOA encourages collaborative applications from U.S. and LMIC institutions to support training to achieve technical, administration and financial management expertise required for one of the six research infrastructure functions considered critical to a successful high quality research environment:Research administration and management;Research integrity oversight;Ethical review of research for the protection of human subjects;Laboratory animal welfare oversightHealth sciences library and information services; andInformation and communications technology systems (ICT) for researchResearch infrastructure training programs will maximize previous investments and further strengthen the LMIC institution's research capabilities, and provide more accessible research infrastructure training opportunities to others in their own country and in other LMICs.

Pursuant to the Foreign Assistance Act of 1961, as amended, the United States Government, as represented by the U.S. Agency for International Development (USAID), the Bureau for Development, Democracy, and Innovation (DDI), Inclusive Development Hub (ID) is announcing the Alliance to Advance Protection and Care for Children in Adversity (APCCA) Annual Program Statement (APS). Through the APCCA Alliance APS, USAID aims to address key objectives outlined in the U.S. Government (USG) Advancing Protection and Care for Children in Adversity Strategy. The purpose of this APS is to disseminate information to prospective Applicants so they may develop and submit Concepts in response to future Addenda under this APS and ultimately to be considered for USAID funding. USAID DDI/ID anticipates awarding multiple grants and/or cooperative agreements as a result of this APS. However, issuance of this APS does not constitute an award commitment on the part of the U.S. Government, nor does it commit the USG to pay for any costs incurred in the preparation or submission of comments/suggestions, a concept, or an application. Concepts and Applications are submitted at the risk of the applicant. All preparation and submission costs are at the applicants expense. The actual number of assistance awards, if any, under this APS is subject to the availability of funds and the interests and requirements of Operating Units (OUs) as well as the viability of eventual Full Applications received. There is no predefined minimum or maximum number of awards USAID OUs will support through this APS. The APCCA APS is unfunded and serves as a general umbrella APS, to which any USAID OU can post specific Addenda that are focused on challenges or priorities highlighted in the APS. An Addendum highlights a specific program or activity, where technical assistance or partnership opportunities are communicated by a USAID OU. Addenda will be the exclusive source of funding through this APS. NOTE: This APS is not a Request for Applications or a Request for Proposals, and does not serve as a general request for APCCA concepts. USAID will only consider Concepts that are submitted in response to Addenda to this APS. USAID will not accept or consider any Concepts submitted in response to the general APCCA Alliance APS. Addenda will be posted on www.grants.gov. Based on the submitted Concept(s) to specific Addenda opportunities, USAID will determine whether to engage in more in-depth and specific co-creation discussions aimed at further developing the proposed approach and will determine whether to request a Full Application. To be competitive under a particular Addendum to this umbrella APS, Concepts and Full Applications must be fully responsive to all directions under this APS document except when specifically noted otherwise in the Addendum. Please refer to the full APS document attached for full information and details about this opportunity.

The "Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes" grant aims to fund research projects that prepare for clinical trials in rare diseases by developing effective strategies for testing potential treatments or diagnostics, improving success rates with robust biomarkers and assessment measures, or by understanding the progression of a rare disease to design future clinical trials.

This funding opportunity provides operational support for the National Biocontainment Laboratories at Boston University and the University of Texas Medical Branch, enabling critical research on hazardous biological agents and biodefense initiatives.

This funding opportunity provides financial support for research projects aimed at overcoming barriers to HIV prevention for marginalized individuals who use substances, focusing on improving access to and retention in PrEP care.

This funding opportunity supports U.S. research institutions in training and developing Ph.D. students from underrepresented groups in biomedical research to address national health-related challenges.

The purpose of this Funding Opportunity Announcement (FOA) is to support innovative multidisciplinary and multi-level research designed to develop and/or test interventions to optimize care of persons with Type 2 diabetes from populations with health/health care disparities concordant with evidence-based guidelines. NIH-designated health disparity populations include racial and ethnic minorities (Blacks/African Americans, Hispanics/Latinos, American Indians/Alaska Natives, Asians, Native Hawaiians and other Pacific Islanders), sexual and gender minorities, socioeconomically disadvantaged populations, and underserved rural populations. Proposed projects would be expected to develop and/or test patient-centered strategies, which in addition to optimal glycemic control, would aim at completing other recommended guidelines (e.g., annual eye/foot and urine albumin exam, optimal blood pressure control, intake of ACEIs or ARBs/statin/aspirin and influenza/pneumonia vaccines).

This funding opportunity is designed to support local organizations in Illinois that provide essential nursing care and support services to high-risk pregnant and postpartum individuals and their infants, aiming to improve health outcomes and reduce disparities in maternal and infant health.

This funding opportunity supports U.S. institutions in developing educational programs for psychiatry residents to enhance their research skills and encourage careers in mental health research.

This funding opportunity supports research and training in mathematical modeling to improve the prevention and management of infectious diseases in healthcare settings, targeting early-career modelers and collaboration with public health institutions.

This funding opportunity invites research institutions to join a collaborative effort aimed at advancing stillbirth research, particularly focusing on reducing stillbirth rates in vulnerable populations through innovative scientific approaches.

The OHSU Knight Cancer Institute's Community Partnership Program (CPP) is designed to cultivate sustainable collaborations with Oregon communities to address identified cancer needs. The program's mission is to partner with these communities as allies in the Knight Cancer Institute's goal of ending cancer. This aligns with a broader strategic priority to enhance community-OHSU collaboration on local cancer issues and disparities, fostering long-term sustainability of local efforts. The CPP targets various Oregon community groups, including organizations, schools, government bodies, health/medical clinics, health systems, and businesses. A key focus is on proposals that address cancer-related health disparities and increase equity for historically disadvantaged and/or marginalized Oregon communities. Organizations led by and/or committed to serving these populations are highly encouraged to apply, underscoring the program's commitment to equitable cancer outcomes. The program's priorities revolve around supporting communities in identifying and addressing pressing cancer-related needs, enhancing collaboration, and building community skills for sustainable long-term efforts. This is operationalized through three grant tiers. Tier 1, "Define Need," focuses on developing local action plans through needs assessments or committee formation. Tier 2, "Develop and Pilot," supports the development and piloting of programs to address priority cancer issues or disparities. Tier 3, "Evaluate and Sustain," aims to evaluate existing approaches and establish sustainability strategies. Expected outcomes include communities effectively identifying their most pressing cancer-related needs, increased collaboration between OHSU and local communities, and enhanced capacity within communities to sustain efforts addressing local cancer issues. Measurable results would be tied to the specific objectives of each tier, such as the completion of community cancer needs assessments (Tier 1), the successful piloting of new programs (Tier 2), and the evaluation and sustained implementation of effective approaches (Tier 3). The overall impact goal is to collectively work towards ending cancer as communities know it, with a strong emphasis on reducing health disparities.

This funding opportunity provides financial support for the development of innovative informatics tools that will help researchers effectively utilize the human pangenome reference to advance genomics research across various applications.

This funding opportunity provides financial support to organizations that deliver comprehensive family planning services to help reduce unintended pregnancies and improve reproductive health for individuals in Texas.

This funding opportunity provides financial support to various organizations for developing and implementing public health strategies aimed at improving brain health and addressing the challenges of Alzheimer’s disease and related dementias, particularly for underserved populations.

To advance the field of patient-centered clinical decision support through research that tests tools and resources in real-world settings. The mission of the Agency for Healthcare Research and Quality (AHRQ) is to produce evidence to make healthcare safer, higher quality, and more accessible, equitable, and affordable, and to work within the U.S. Department of Health and Human Services and with other partners to make sure the evidence is understood and used. The purpose of this Notice of Funding Opportunity (NOFO) is to conduct research on patient-centered clinical decision support (PC CDS), a nascent area within the larger field of CDS. Through the AHRQ-funded Patient Centered Outcomes Research (PCOR) CDS Initiative and the CDS Innovation Collaborative specifically, PC CDS resources are now publicly available for interested researchers to further build upon, develop, and test, in real-world settings. Innovative research is needed to understand how to make traditional, clinician-facing CDS more patient-centered, while also engaging patients, families, and caregivers in a co-design process to design and implement these tools. BACKGROUND Clinical decision support refers to digital tools that are used to help inform patient care. Patient-centered clinical decision support (PC CDS), in contrast to traditional clinician-facing CDS, is CDS that focuses on the patient, or their caregiver, and facilitates their active involvement in healthcare decision-making with their clinicians. PC CDS uses information from patient-centered outcomes research findings and/or patient-specific information and has the potential to be transformative by enabling higher-quality care delivery and improved outcomes. PC CDS can also support shared decision making (SDM), which AHRQ defines as a collaborative process in which patients and clinicians work together to make healthcare decisions informed by evidence, the care team's knowledge and experience, and the patient's values, goals, preferences, and circumstances. PC CDS can also support shared care planning enabling patients, caregivers, and clinicians to work together to tailor a clinical plan to align with a given patients priorities and goals. PC CDS is a developing field and has the potential to increase the quality and experience of patient care. AHRQ’s CDS Initiative is supported by the Patient Centered Outcomes Research Trust Fund (PCOR TF) and is guided by AHRQ’s PCOR TF strategic framework (https://www.ahrq.gov/pcor/strategic-framework/index.html). Since 2016, AHRQ’s PCOR CDS Initiative has been building tools, concepts, frameworks, and conducting pilot projects. Much of AHRQ’s recent effort has focused on patient-centered CDS, and several past projects have generated resources that could be highly useful to the developing PC CDS field. Examples of these projects include AHRQ’s PC CDS Learning Network and CDS Connect, as well as a project that assessed the current state and future directions with PC CDS. Additional information for CDS projects is available on the PCOR CDS Initiative webpage. AHRQ’s most recent PC CDS project, the CDS Innovation Collaborative, or CDSiC, is a multi-component stakeholder-driven initiative that produced a rich set of resources and tested concepts around different aspects of PC CDS. As part of the CDSiC, four workgroups were formed, each around a specific area of PC CDS, with the charge to create products (e.g., frameworks, guides, checklists) that could be used in the clinical field to establish or measure use of PC CDS. These products could address clinical workflows or the development of CDS technologies, among other areas related to PC CDS. During the first two years of the CDSiC, these workgroups created numerous products that addressed PC CDS in different areas. These areas included CDS outcomes, trust and patient-centeredness, and scaling and dissemination. One workgroup also focused on the existing standards and regulatory frameworks that could impact the future uptake and use of PC CDS. Applicants can examine, using these products and tools, how PC CDS can support shared decision making and care planning among individuals with complex needs including older adults, people living with multiple chronic conditions, frailty, disabilities, and/or socioeconomic disadvantage and how this may foster the delivery of person-centered care. They may also study strategies to scale and spread effective tools including use in lower resourced and safety net instituions. Applicants responding to this NOFO must propose to use the resources developed by AHRQ's PCOR CDS Initiative, or any of the many products developed by the ongoing CDSiC, to further explore their usefulness, impact, and practical application in real-world settings. For example, CDSiC products that could be used may include the Taxonomy of Patient Preferences, Integration of Patient-Centered CDS into Shared Decision Making, Approaches to Measuring Patient-Centered CDS Workflow and Lifeflow Impacts, or the PC CDS Performance Measurement Inventory User Guide. Links to and descriptions of the products are available on the CDSiC Stakeholder Center webpage (https://cdsic.ahrq.gov/cdsic/cdsic-stakeholder-community-outreach-center ) The CDSiC's Innovation Center (https://cdsic.ahrq.gov/cdsic/innovation-center) developed a comprehensive report around measurement of PC CDS and created two pilot dashboards that can help clinicians understand and use Patient Generated Health Data. Additional information on other PCOR CDS projects is available at https://cds.ahrq.gov/about. Examples of Highly Responsive Projects include: A community hospital with a large priority population, selects from the CDSiC portfolio of projects generated by the Trust and Patient-Centeredness workgroup. The recipient selects the source credibility product from the Trust and Patient Centeredness workgroup and conducts a study to understand how their population perceives the information they receive from within their existing electronic health record (EHR) system. Patients provide input, and the approach is assessed against existing CDS tools, as well as the definition of PC CDS as defined by the CDSiC, to assess their level of patient-centeredness. A small startup company is developing applications (apps) to help patients improve their healthcare. The startup leverages two products from the CDSiC standards and regulatory frameworks workgroup: Advancing Standardized Representations for Patient Preferences to Support Patient-Centered Clinical Decision Support and an Environmental Scan that reveals opportunities to evolve standards and regulatory frameworks to advance PC CDS. The company works with a patient advocacy organization to co-design the patient-facing PC CDS app, uses standards to leverage existing patient generated health data (PGHD), and incorporates a final assessment as to the level of patient-centeredness of their technology. A primary care physician group is working to reduce clinician burnout with the goal of improving patient outcomes. The group looks at the CDSiC’s Taxonomy of Patient Preferences and assesses how they can incorporate these concepts into restructured workflows. The group then also uses CDSiC’s product called Approaches to Patient-Centered CDS Workflow and Lifeflow Impact, which provides a framework to help identify the optimal point for a patient-centered CDS tool’s deployment in a patient’s lifeflow. Their study will also assess how increased patient-centeredness in their CDS tools do not inadvertently have a negative impact on clinician workflows or experience. All projects are encouraged to: Incorporate Clinical Quality Language (CQL) and other HL7 standards into their project design, if appropriate for developing, integrating, (or modifying) their CDS with their EHR system or other health information technology (Health IT) components to become more patient-centered. OBJECTIVES AND SCOPE This NOFO aims to support innovative collaborative research to understand how clinical decision support tools in real-world settings can be improved to become more patient centered. Recipients will become part of an existing community of researchers who have an interest in PC CDS including AHRQ, the CDSiC, and other researchers. Interested applicants may include health information technology experts, patient advocates and representatives, clinicians, electronic health record developers, policymakers, payors, as well as leaders from research and academic medical institutions. All projects must: Utilize one or more of the products from the CDSiC or the PCOR CDS Initiative, which are available on the project website: cdsic.ahrq.gov, or another resource available from the PCOR CDS Initiative (cds.ahrq.gov), which includes the PC CDS Learning Network, CDS Connect, or AHRQ's Evaluation project that assessed the current state and future directions with PC CDS; If CDSiC products are used specifically, applicants must identify if any other frameworks are being used to evaluate the performance of their PC CDS (e.g., RE-AIM or other); Apply the definition of patient-centered CDS (available here: https://cdsic.ahrq.gov/cdsic/patient-centered-clinical-cds-infographic) and describe the degree to which each of the 4 elements are incorporated into the patient-centered CDS tool: knowledge, patient data, delivery, and use. Apply an equity lens, consistent with AHRQ's PCOR Strategic Framework. Apply at least 1 of the 4 priorities from AHRQ's PCOR Strategic Framework. Include meaningful and substantial participation from patients and/or patient representatives in the co-design, implementation, and evaluation of their research, to also be reflected in the proposed budget. Fully describe their research ecosystem. If developing or extending a digital tool, be mobile friendly to be more accessible to a broader population (for example, a patient-facing portal, website, etc.). If the research or tool will be incorporated into an EHR system, the facility must have a mature, functioning EHR system (e.g., the facility is not planning any significant system upgrade or migration). Otherwise, an alternative means to test and evaluate the selected CDS product can be described. If the research strategy intends to modify an existing clinical workflow that is currently clinician-focused, to become a patient-centric or patient-facing approach, then the strategy must include an evaluation component to characterize the performance of the PC CDS tool versus the previous clinician-facing workflow. If the proposed project plans to promote implementation of SDM, it should align with AHRQ’s definition of SDM (available here: https://www.ahrq.gov/sdm/about/index.html) and include at least one validated measure of SDM in its evaluation.