Grants for Nonprofits - Income Security and Social Services

This funding opportunity supports collaborative research projects aimed at addressing brain and nervous system disorders in low- and middle-income countries, focusing on building sustainable research capacity and improving neuro-health outcomes.

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. This Funding Opportunity Announcement (FOA) encourages Exploratory/Developmental Phased Innovation (R61/R33) grant applications to support development of clinical trials to treat critical and co-occurring health conditions in individuals with Down syndrome. The proposed research aims should be milestone-driven. The total project period for an application submitted in response to this FOA may not exceed five years. This FOA provides support for up to two years (R61 phase) for preliminary/developmental/planning studies, followed by possible transition to clinical trial support (R33) of up to three years, although the total duration of the award may not exceed five years. This FOA requires measurable R61 milestones.

This funding opportunity supports organizations in Philadelphia and Camden that create free outdoor programs to help underserved communities access and enjoy parks, trails, and waterways.

This grant provides funding to establish a comprehensive online resource for research and policy information to support child care and early education programs, helping agencies improve access to valuable research for children from birth to age 13.

This funding opportunity provides financial support to nonprofit organizations, clinics, and health centers in Washington, DC, to implement innovative programs that improve maternal and child health outcomes, particularly for underserved populations in Wards 7 and 8.

The purpose of this Notice of Funding Opportunity (NOFO) is to solicit research designed to capacitate, transform, and scale the delivery of HIV testing, prevention, and care services through pharmacists and pharmacies in US and/or global settings. This includes theadvancement of training curricula to enable pharmacy students, pharmacists, pharmacies, and pharmacy systems to deliver the spectrum of needed HIV services with ease, equity, and effectiveness. This NOFO uses the R21 grant mechanism, while RFA-MH-25-185 uses the R01 mechanism. Projects that lack preliminary data or that propose to pilot a novel intervention may be most appropriate for the R21 mechanism. Applications with preliminary data and those proposing large-scale clinical trials or longitudinal analyses should consider using the R01 mechanism.

The Community Foundation of Middle Tennessee is currently accepting applications for its Lillian Ashley Fund, a grant program established by Manchester, Tennessee native Lillian Ashley. This endowment reflects Lillian's desire to give back to her beloved community, focusing on areas close to her heart: children, animals, and environmental conservation within Coffee County. The program's core mission aligns with the foundation's broader goal of supporting community well-being by channeling resources to vital local initiatives. The primary beneficiaries of the Lillian Ashley Fund are the children, youth, and animals of Coffee County, as well as local environmental and conservation efforts. The fund aims to support the overall well-being of children and youth, provide for the care and welfare of animals, and bolster initiatives that protect and preserve the environment. The expected outcomes include improved quality of life for young residents, enhanced care and protection for animals, and a healthier, more sustainable environment within the county. The fund's strategic priorities are clearly defined: supporting the well-being of children and youth, ensuring the care and welfare of animals, and promoting environment and conservation efforts. These focus areas are intended to create a tangible impact on the community, addressing specific needs identified by the donor. While measurable results are not explicitly detailed in terms of specific metrics, the grant period of December 1, 2024, to November 30, 2025, suggests an expectation of progress within that timeframe, contributing to the broader theory of change that targeted funding can lead to significant positive community development in these key areas. Eligible organizations for this grant include 501(c)(3) public charities and governmental entities such as libraries or departments. Nonprofits can request grants up to a maximum of $15,000, with the overall fund size ranging from $10,000 to $100,000. This targeted approach allows the Community Foundation of Middle Tennessee, through the Lillian Ashley Fund, to strategically invest in local organizations that are directly addressing the program's goals and contributing to the sustained betterment of Coffee County's children, animals, and environment.

The Office of Family Violence Prevention and Services program (OFVPS) Discretionary Grant Program under the Family Violence Prevention and Services Act (FVPSA): Specialized Services for Abused Parents and Their Children (Demonstration Projects) will support fifty (50) demonstration projects. These projects will focus on expanding the capacity (of coalitions, local programs, and community-based programs) to prevent future family violence, domestic violence, and dating violence by appropriately addressing the needs of children exposed to domestic violence, and the potentially co-occurring impacts of child abuse and neglect.

This funding opportunity provides financial support to non-profit organizations for projects that improve public facilities and services for low and moderate-income residents in Glendale.

Grants for Workforce Development Innovation Initiatives in the District of Columbia are available to support innovative solutions for residents to enter and sustain employment, ultimately contributing to the District's economy. The grant program encompasses various areas such as youth programs, initiatives for returning citizens and adults with barriers to employment, labor market research, workforce and federal programs, labor standards, unemployment insurance outreach, paid family leave support, and infrastructure job assistance. Service categories include work readiness, job readiness, occupational skills development, job placement assistance, research, and education/outreach efforts.

The purpose of the The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative Fellows (F32) program is to enhance the research training of promising postdoctorates, early in their postdoctoral training period, who have the potential to become productive investigators in research areas that will advance the goals of the BRAIN Initiative. Applications are encouraged in any research area that is aligned with the BRAIN Initiative, including neuroethics. Applicants are expected to propose research training in an area that clearly complements their predoctoral research. Formal training in analytical tools appropriate for the proposed research is expected to be an integral component of the research training plan. In order to maximize the training potential of the F32 award, this program encourages applications from individuals who have not yet completed their terminal doctoral degree and who expect to do so within 12 months of the application due date. On the application due date, candidates may not have completed more than 12 months of postdoctoral training.

This funding opportunity supports researchers in studying and characterizing genetically modified mice that exhibit early life lethality or reduced viability, contributing to our understanding of gene function and its implications for human health.

The Minnesota Housing, in collaboration with Greater Minnesota Housing Fund (GMHF), is launching the Single Family RFP through its Community Homeownership Impact Fund. This initiative is designed to expand and preserve affordable homeownership opportunities across all counties in Minnesota. The program’s mission aligns closely with the foundation’s broader vision: ensuring that every Minnesotan has access to safe, affordable, and sustainable housing. By focusing on single-family, owner-occupied homes, this funding opportunity aims to address both supply and quality gaps, particularly in underserved and economically marginalized communities. Through multiple financing mechanisms—grants, deferred loans, housing infrastructure bonds, and interim loans—the program seeks to foster community stability, economic inclusion, and equitable pathways to homeownership. The program’s primary beneficiaries are low- to moderate-income households, with a targeted emphasis on households of color, immigrant households, and those including people with disabilities. This focus reflects GMHF’s commitment to applying a racial and economic equity lens to homeownership initiatives, aiming to reduce historic disparities in property ownership and wealth accumulation. Targeted investments will support both the creation of new affordable housing units and the rehabilitation of existing homes, ensuring that communities not only gain new housing stock but also preserve their existing neighborhoods. Special priority will be given to applicants leveraging cross-sector collaborations—particularly in health and housing—to improve overall community well-being. Strategically, the program prioritizes projects that deliver tangible, lasting impact. Priority activities include acquisition, rehabilitation, and resale of existing properties; new construction of single-family homes; and stand-alone affordability gap assistance. Additional emphasis is placed on projects that advance Tribal housing initiatives, ensuring that Tribal Nations and communities have equitable access to homeownership opportunities. By offering flexible funding types—including forgivable loans and deferred downpayment assistance—the program allows local governments, nonprofits, Tribal entities, and developers to structure their projects to meet community-specific needs and financial realities. Expected outcomes are centered on measurable, high-impact results. Awarded projects must lead to the creation or preservation of affordable, owner-occupied homes with no more than four units, ensuring at least one unit is owner-occupied. The program anticipates that these efforts will expand the affordable housing inventory, increase homeownership rates among underrepresented populations, and stabilize neighborhoods. Success metrics will include the number of homes developed or rehabilitated, the number of households served, demographic diversity among beneficiaries, and the degree to which affordability thresholds are met and maintained. Additionally, the program seeks to generate long-term community benefits such as improved health outcomes, greater neighborhood investment, and increased intergenerational wealth. The foundation’s strategic priorities and theory of change rest on the belief that stable, affordable homeownership is a critical lever for advancing economic mobility and community resilience. By combining capital investment with equitable housing strategies, the program aims to dismantle systemic barriers to homeownership and create conditions for sustained prosperity. Through partnerships with municipalities, Tribal governments, nonprofits, and developers, Minnesota Housing and GMHF are fostering a collaborative ecosystem that ensures funding leads to meaningful, measurable, and community-driven change. This initiative is not merely about building houses—it’s about empowering people, strengthening communities, and reshaping the housing landscape in Minnesota for a more inclusive future.

This grant provides funding to nonprofit organizations in Perry County, Pennsylvania, to support projects that enhance community well-being in areas such as arts, education, health, and substance abuse prevention.

The Community Climate Action Grant program, spearheaded by Albemarle County, aims to foster local projects that bolster the community's capacity to diminish greenhouse gas emissions. This initiative directly aligns with the county's broader mission to implement its Climate Action Plan, which was adopted in 2020. By leveraging external community resources and local groups, the program seeks to make climate action a more inclusive and participatory process, thereby extending the reach and impact of governmental efforts to combat climate change. The primary beneficiaries of this grant program are community-based nonprofit organizations with 501(c)(3) tax-exempt status, or those affiliated with a 501(c)(3) fiscal sponsor, that are principally and physically located in Albemarle County. Groups located outside the county may also apply if they can demonstrate that their services will primarily benefit people or places within Albemarle County. The impact goals are centered on tangibly advancing the goals, strategies, and actions outlined in the County’s Climate Action Plan, with a clear focus on reducing greenhouse gas emissions and increasing carbon sequestration. The program prioritizes projects that contribute to reducing greenhouse gas emissions across various sectors, including transportation, buildings, waste, agriculture, and natural areas. Additionally, it supports initiatives that increase carbon sequestration in agriculture or natural systems. The grant explicitly aims to achieve four key program goals: reduce greenhouse gas emissions, advance equity and inclusion, build community, and support thoughtful and achievable projects. These goals underscore the county's strategic priorities, emphasizing not just environmental impact but also social equity and community engagement as integral components of effective climate action. Expected outcomes include a measurable reduction in greenhouse gas emissions within Albemarle County, an increase in community participation and inclusivity in climate action efforts, and the successful implementation of diverse projects that align with the county’s Climate Action Plan. The program's theory of change posits that by empowering and funding local community groups, the county can harness a wider range of innovative solutions and foster a more widespread commitment to climate resilience. Grant requests can range from $5,000 to $25,000, with a total of $100,000 available for 2024, indicating a strategic investment in multiple, impactful local initiatives rather than a single large-scale project.

This funding opportunity provides financial support to public and nonprofit organizations that deliver outreach services to homeless and at-risk youth, helping them access essential resources and safer living conditions.

This funding opportunity supports nonprofit organizations and destination marketing groups in Fairfield County, South Carolina, to develop projects that attract tourists and boost the local economy through targeted advertising and enhanced recreational and cultural experiences.

This program provides funding to various organizations and government entities in Utah to improve access to high-speed internet, affordable devices, and digital skills training for residents, aiming to bridge the digital divide across the state.

The Tennessee Department of Agriculture (TDA) is offering the Community Tree Planting Program, funded by the Tennessee Agricultural Enhancement Program (TAEP) through the 2008 State Legislature. This grant program is administered by the Division of Forestry’s Urban and Community Forestry Program. The core mission of this grant is to increase the tree resource base in cities and towns across Tennessee, focusing on the functional benefits of urban trees rather than solely on beautification. The primary beneficiaries of this program are communities and local units of government, non-profit organizations, and elementary, secondary, and higher education institutions within Tennessee. The impact goal is to enhance the state's urban tree resources to provide direct cost-saving benefits to communities. These benefits include energy savings through shading, storm water mitigation, rain interception, and improved air quality through filtration and absorption. The program's priorities and focuses are explicitly not beautification but rather the practical, environmental services that trees provide. It emphasizes that trees are "work horses for communities." Recommended goals and objectives for applicants include statements about urban trees providing cooler temperatures, cleaner air, reduced flooding and erosion, improved human health, and food and shelter for wildlife. Expected outcomes and measurable results revolve around the increase in the tree resource base and the subsequent realization of the aforementioned environmental and economic benefits. While specific metrics are not detailed in the provided text, the focus on quantifiable benefits like energy savings and storm water mitigation implies an expectation of measurable improvements in these areas. The grant contracts will run from December 1, 2024, to April 30, 2025, suggesting that the initial outcomes will be assessed within this timeframe. Eligible applicants can apply for grants ranging from $500 to $20,000, which further indicates a focus on smaller, community-level projects with clear, achievable objectives.

This funding supports institutions in developing training programs for predoctoral and postdoctoral researchers in biomedical and clinical fields, with a focus on enhancing diversity and preparing trainees for successful research careers.