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Explore 2,482 grant opportunities

INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Clinical Trial Readiness (R21 Clinical Trial Not Allowed)
$275,000
HHS-NIH11 (National Institutes of Health)
Federal

Application Deadline

Jul 1, 2024

Date Added

Apr 5, 2022

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. This Funding Opportunity Announcement (FOA) invites researchers to submit applications for support of clinical projects that address critical needs for clinical trial readiness in Down syndrome. This initiative seeks applications that are intended to facilitate Down syndrome research by enabling efficient and effective movement of candidate therapeutics or diagnostics towards clinical trials for Down syndrome and its co-occurring conditions, and to increase their likelihood of success through development and testing of biomarkers and clinical outcome assessment measures, development and testing of novel trial methods and recruitment strategies, or by defining the presentation and course of the co-occurring conditions in individuals with Down syndrome to enable the design of future clinical trials.

Education
State governments
NCI Research Specialist (Clinician Scientist) Award (R50 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 4, 2025

Date Added

Aug 23, 2024

This funding opportunity provides financial support to exceptional clinician scientists who contribute to the development and implementation of NCI clinical trials, ensuring their continued involvement in cancer research without being principal investigators on research project grants.

Education
State governments
Effect of HIV and Substance Use Comorbidity on the Placenta and Maternal Outcomes (R01 Clinical Trial Optional)
$2,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 15, 2024

Date Added

Oct 30, 2023

This grant provides funding for research on how HIV and substance use affect placental health and maternal outcomes, targeting a wide range of institutions and researchers focused on these critical health issues.

Education
State governments
Advancing Research on Molecular Targets and Mechanisms that Influence the Interplay Between Sex Hormones, HIV, and Addictive Substances (R01 Clinical Trials Not Allowed)
$400,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 13, 2025

Date Added

Aug 16, 2024

This grant provides funding for research projects that explore how sex hormones affect HIV progression and substance use disorders, aiming to develop new therapeutic strategies for these interconnected health issues.

Education
State governments
Interventions to expand cancer screening and preventive services to ADVANCE health in populations that experience health disparities (R01, Clinical Trial Required)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 19, 2024

Date Added

Apr 19, 2023

This funding opportunity supports research projects that develop and test innovative strategies to improve cancer screening and preventive services for populations facing health disparities, such as racial and ethnic minorities, low-income groups, and rural communities.

Education
State governments
Early Head Start Expansion and Early Head Start-Child Care Partnership Grants
$20,509,347
HHS-ACF-OHS (Administration for Children and Families - OHS)
Federal

Application Deadline

May 14, 2024

Date Added

Mar 6, 2024

The Administration for Children and Families (ACF), Office of Head Start (OHS) announces the availability of approximately $102 million to be competitively awarded for the purpose of expanding access to high-quality, comprehensive services to low-income infants, toddlers, and their families through Early Head Start-Child Care (EHS-CC) Partnerships, or through the expansion of Early Head Start services. ACF solicits applications from public entities, including states, or private non-profit organizations, including community-based or faith-based organizations, or for-profit agencies that meet eligibility for applying as stated in section 42 U.S.C. 9840A of the Head Start Act. Interested applicants may email [email protected] for additional information.OHS encourages interested applicants to visit https://www.acf.hhs.gov/grants/how-apply-grant. This webpage provides information on applying for grants, registering and applying through Grants.gov, submitting an application, and understanding the grant review process.

Income Security and Social Services
State governments
Pancreatic Cancer Detection Consortium: Research Units (U01 Clinical Trial Optional)
$600,000
HHS-NIH11 (National Institutes of Health)
Federal

Application Deadline

Jun 11, 2024

Date Added

Sep 16, 2021

The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications for the Research Units (RUs), one of the two scientific components of the Pancreatic Cancer Detection Consortium (PCDC), to conduct research on early detection of pancreatic ductal adenocarcinoma (PDAC) and characterization of its precursor lesions to identify those patients who are at high risk of progression to cancer. The PCDC will continue to address one of the four research priorities identified in the National Cancer Institute's 2014 Scientific Framework for Pancreatic Ductal Adenocarcinoma. The PCDC will support research for the development and testing of new molecular and imaging biomarkers for detecting PDAC early and for identifying those patients at high risk of PDAC (because of genetic factors or presence of precursor lesions) who could be candidates for early intervention. The PCDC-RUs will consist of multi-disciplinary teams and will undertake studies to: identify and test biomarkers measurable in bodily fluids for early detection of PDAC and/or its precursor lesions; determine which pancreatic cysts are likely to progress to cancer; develop molecular- and/or imaging-based approaches for screening populations at high risk of PDAC; use machine learning and computational approaches towards biomarker discovery and/or validation; and conduct biomarker validation studies. The PCDC-RUs will also collect longitudinal biospecimens for building a biorepository. Each PCDC-RU is expected to participate in collaborative activities with other PCDC-RUs and share ideas, biospecimens and data within the Consortium. The other scientific component of the PCDC will be the Management and Data Coordination Unit (MDCU). The PCDC-MDCU will provide support toward study design, protocol development, statistical analysis, coordination, harmonization, data management and stewardship for the trans-PCDC collaborative projects, including biorepository building effort. The PCDC-MDCU will also supp

Education
State governments
NINDS Sustainable Transformation of Institutional Research Rigor (STIRR) Program (RC2 - Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 30, 2024

Date Added

May 2, 2023

This funding opportunity provides financial support to U.S. academic and nonprofit institutions to implement innovative programs that enhance research rigor and transparency in neuroscience, fostering a culture of high-quality scientific practices.

Health
State governments
Advancing Genomic Medicine Research (R01 Clinical Trial Optional)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 19, 2024

Date Added

Nov 6, 2023

This funding opportunity provides financial support for researchers to explore innovative ways to integrate genomic information into clinical care, particularly focusing on diverse and underserved populations to improve health equity.

Education
State governments
National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders (U01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 25, 2025

Date Added

Jun 5, 2025

This funding opportunity supports multidisciplinary teams in developing and testing innovative drugs and devices to treat mental disorders, encouraging collaboration between academia and industry.

Health
State governments
Resource-Related Research Projects for Development of Animal Models and Related Materials (R24 Clinical Trials Not-Allowed)
$5,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 25, 2025

Date Added

May 22, 2025

This funding opportunity supports the development and enhancement of animal models and related biological tools that are broadly applicable to various areas of biomedical research, aimed at improving our understanding of human diseases and advancing therapeutic interventions.

Health
State governments
Microglial Pathophysiology in Comorbid Substance Use Disorder (SUD) and HIV (R61/R33 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 25, 2024

Date Added

Jul 19, 2023

This grant provides funding for researchers to explore how HIV and substance use disorders affect protein interactions in microglia, aiming to uncover mechanisms that could lead to new treatments for these interconnected conditions.

Education
State governments
NIH SIREN Neurologic Clinical Trials (UG3/UH3 - Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 7, 2024

Date Added

Feb 8, 2023

This funding opportunity announcement (FOA) encourages applications for multi-center clinical trials focused on neurological emergencies. Successful applicants will collaborate and conduct the trial within the NIH SIREN Network. The NIH SIREN Clinical Coordinating Center (CCC) will work with the successful applicants to implement the proposed trial efficiently and the SIREN Data Coordinating Center (DCC) will provide statistical and data management support. The NIH SIREN hubs and their affiliated clinical sites will provide on-site implementation of the clinical protocols.The NIH SIREN Network will also be uniquely poised to collaborate with other US and international consortia necessary to conduct larger, definitive trials of promising interventions for neurological emergencies.Multi-center clinical trials in stroke treatment, recovery, or prevention supported by NINDS will be conducted in the NIH StrokeNet, and not within SIREN. Applicants do not need to be part of the existing SIREN infrastructure to apply under this FOA.

Health
State governments
Disseminating PCOR Evidence for Long COVID Care into Practice Through Up-to-Date Clinical Decision Support
Contact for amount
U.S. Department of Health & Human Services (Agency for Health Care Research and Quality)
Federal

Application Deadline

Mar 19, 2025

Date Added

Jan 13, 2025

This funding opportunity provides financial support to healthcare organizations and educational institutions for developing clinical decision support systems that integrate the latest research on Long COVID care, with a focus on improving patient outcomes and equity in underserved populations.

Health
State governments
Revision Applications for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (R01 Clinical Trial Optional)
$150,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 3, 2025

Date Added

Jan 2, 2025

This funding opportunity is designed for researchers with existing NCI R01 grants to integrate innovative cancer research technologies into their projects, enhancing the study's impact and advancing the field of cancer research.

Education
State governments
Research on Autism Spectrum Disorders (R21 Clinical Trial Optional)
$200,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 16, 2024

Date Added

Apr 30, 2024

This funding opportunity supports innovative research projects aimed at understanding and improving the diagnosis, treatment, and services for individuals with Autism Spectrum Disorders, welcoming applications from a diverse range of organizations, including universities and nonprofits.

Environment
State governments
State-Tribal Partnerships to Implement Best Practices in Indian Child Welfare
$2,000,000
HHS-ACF-CB (Administration for Children and Families - ACYF/CB)
Federal

Application Deadline

Jun 20, 2024

Date Added

Aug 3, 2023

American Indian and Alaska Native (AI/AN) children are nearly 3 times more likely to enter foster care, compared to non-Native children. These four year grants are intended to generate evidence for how best to effectively implement child welfare practices and ongoing active efforts to maintain AI/AN families by funding state and tribal partnerships to jointly design and operate Indian child welfare best practice implementation demonstration sites. The evidence generated and lessons learned through this effort are intended to contribute to implementation efforts nationally to help maintain and preserve AI/AN families and allow their children to remain connected to their communities and cultures. The purpose of this notice of funding opportunity is to create and implement intergovernmental partnership models to improve implementation of child welfare best practices that are culturally appropriate for federally recognized AI/AN children to prevent maltreatment, removal from families and communities, and improve safety, permanency, and well-being. Recipients will serve as demonstration sites to design and implement projects to effectively implement culturally appropriate best practices in Indian child welfare, including research and evaluation of improvements in child welfare practice, Indian child welfare codes, legal and judicial processes, case monitoring, case planning, data collection, in-home family preservation services, infrastructure, and systems change. Partnerships must include the state Court Improvement Program, the state child welfare agency, and one or more tribal governments or tribal consortia including corresponding tribal court(s). The "Tribal government" partner(s) may be tribal child welfare agencies where appropriate under tribal law or custom.Effective culturally appropriate best practices for implementation require a high degree of collaboration between state and tribal courts and Indian child welfare agencies. Thus, both states and tribes must identify, build, and enhance necessary capacities. State/tribal collaborations will work together to craft solutions for longstanding challenges to providing effective best practices in Indian child welfare in ways that work best for their communities. This funding opportunity is intended to encourage state and tribal governments to work together to find creative, rational ways to meet the needs of AI/AN families with culturally appropriate best practices in Indian child welfare, with active efforts to retain or reunite Indian children with family as the gold standard for best Indian child welfare practice. The award also provides an important opportunity for states and tribes to build or strengthen relationships of trust by working together toward common family preservation goals. As part of the project, recipients may also consider the role of civil legal services in implementation efforts. Assessment of the effectiveness and/or need for legal representation to parties in Indian child welfare cases may be included in project work, as may provision of direct civil legal services, to the extent that such legal services are an identified part of a pilot or practice model to be tested.For purposes of this funding opportunity, "Tribal courts" are defined consistent with the Bureau of Indian Affairs regulations as "a court with jurisdiction over child custody proceedings and which is either a Court of Indian Offenses, a court established and operated under the code or custom of an Indian tribe, or any other administrative body of a tribe which is vested with authority over child custody proceedings.

Income Security and Social Services
State governments
Using Archived Data and Specimen Collections to Advance Maternal and Pediatric HIV/AIDS Research (R21 - Clinical Trial Not Allowed)
$275,000
Department of Health and Human Services - National Institutes of Health
Federal

Application Deadline

Jul 24, 2024

Date Added

Apr 27, 2024

The purpose of this Notice of Funding Opportunity (NOFO) is to address the needs of the maternal and pediatric HIV scientific community for research data translation and sharing. This initiative will support secondary data analyses using archived HIV/AIDS data and specimens to generate new research questions and findings relevant to the scientific mission and priorities of the NICHD, Maternal and Pediatric Infectious Disease Branch (MPIDB) and Office of AIDS Research (OAR). The goal of this initiative is to encourage applicants to leverage existing datasets and employ new and advanced analysis techniques to answer scientific questions about the epidemiology, pathogenesis, treatment, clinical manifestations and complications of HIV/AIDS in maternal, pediatric and adolescent populations.

Health
State governments
Influenza Modeling and Forecasting 2024
$14,750,000
U.S. Department of Health & Human Services (Centers for Disease Control - NCIRD)
Federal

Application Deadline

Apr 14, 2025

Date Added

Aug 2, 2024

This funding opportunity is designed to support a network of organizations that will improve influenza modeling and forecasting to enhance public health responses and reduce illness in vulnerable populations.

Health
State governments
Advanced Hydrogen and Fuel Cell Technologies to Drive National Goals
$10,000,000
U.S. Department of Energy (Golden Field Office)
Federal

Application Deadline

Jan 31, 2025

Date Added

Oct 24, 2024

Grant Title: Advanced Hydrogen and Fuel Cell Technologies to Drive National Goals aims to fund research and development of hydrogen and fuel cell technologies to help achieve a net-zero emissions economy by 2050, focusing on clean energy solutions for transportation, industrial processes, and energy storage.

Energy
State governments