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Grants for Nonprofits - Federal

Explore 5,552 grant opportunities

Enforcing Sanctions on China and Russia
$5,000,000
U.S. Department of State (Bureau of International Security-Nonproliferation)
Federal

Application Deadline

Jul 30, 2025

Date Added

Jun 2, 2025

This funding opportunity provides financial support to organizations working to strengthen global efforts against sanctions evasion by China and Russia, focusing on enhancing compliance systems and technical training for public and private sectors.

International Development
For profit organizations other than small businesses
Assistance to Firefighters Grant Program (AFG)
$9,000,000
U.S. Department of Homeland Security (Department of Homeland Security - FEMA)
Federal

Application Deadline

Dec 20, 2024

Date Added

Nov 7, 2024

This program provides financial support to fire departments, emergency medical service organizations, and state fire training academies across the U.S. to improve safety and operations through essential equipment, training, and wellness initiatives.

Law Justice and Legal Services
County governments
DoD Rare Cancers, Resource and Community Development Award
$1,120,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Oct 6, 2025

Date Added

May 2, 2025

This funding opportunity supports the development of research resources and community engagement initiatives to improve outcomes for individuals affected by rare cancers, requiring active involvement from patient advocates throughout the project.

Science and Technology
Nonprofits
Community Infrastructure for Research in Computer and Information Science and Engineering
$5,000,000
National Science Foundation
Federal

Application Deadline

Sep 12, 2025

Date Added

Sep 24, 2024

This grant provides funding to support the development and enhancement of research infrastructure in computer and information science, specifically aimed at fostering diverse research communities across various educational and non-profit organizations.

Science and Technology
Nonprofits
BRAIN Initiative: Brain-Behavior Quantification and Synchronization Transformative and Integrative Models of Behavior at the Organismal Level (U01 Clinical Trials Not Allowed)
$8,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

May 23, 2025

Date Added

May 31, 2024

This funding opportunity supports innovative research teams using non-human animal models to develop advanced methods for measuring and analyzing behavior in relation to environmental factors.

Education
State governments
Chemical Probes and Drugs for Modulating HIV Transcription in the Context of Substance Use Disorders (R01 Clinical Trial Not Allowed)
$400,000
U.S. Department of Health and Human Services - National Institutes of Health
Federal

Application Deadline

Aug 13, 2024

Date Added

Dec 20, 2023

HIV infection and substance use are comorbid conditions that bidirectionally and synergistically influence the deleterious outcomes in people who suffer from substance use disorders (SUD). The persistence and transcriptional reactivation of HIV lead to the development of neuropathological complications. Strategies to address viral latency include silencing of HIV transcription and reactivation and clearance. The goal of this initiative is to support research aimed at (1) identification of targets and pathways by which transcriptional activity of HIV can be suppressed in HIV reservoirs including the CNS in people with SUD, and (2) application of emerging small molecule drug discovery approaches to identify novel compounds that can be utilized as pharmacological probes and as drugs to suppress HIV transcription in people with HIV-SUD comorbidity.

Education
State governments
Developing and Disseminating Strategies to Build Sustainable Lupus Awareness, Knowledge, Skills, and Partnerships
$1,800,000
U.S. Department of Health and Human Services (Centers for Disease Control - NCCDPHP)
Federal

Application Deadline

May 2, 2025

Date Added

Aug 12, 2024

This grant provides funding to national organizations focused on improving lupus awareness, diagnosis, treatment, and self-management among affected populations, particularly women aged 15 to 44.

Health
State governments
Raising Awareness and Building Cooperation to Combat Corruption and Money Laundering
$1,000,000
U.S. Department of State (Bureau of International Narcotics-Law Enforcement)
Federal

Application Deadline

Nov 18, 2024

Date Added

Sep 19, 2024

This funding opportunity provides up to $1 million to U.S. and Mexican organizations to promote awareness and cooperation in combating corruption and money laundering, particularly focusing on legal frameworks like the Foreign Corrupt Practices Act and the Foreign Extortion Prevention Act.

Law Justice and Legal Services
Nonprofits
FY25 IIJA/IRA Bureau of Land Management California Aquatic Resource Management
$225,000
U.S. Department of the Interior (Bureau of Land Management)
Federal

Application Deadline

Mar 8, 2025

Date Added

Jan 8, 2025

This funding opportunity provides financial support to various government entities, nonprofits, and educational institutions for projects that protect and restore California's aquatic resources and ecosystems, particularly benefiting underserved and indigenous communities.

Natural Resources
State governments
FY2025 ABPP - Preservation Planning Grants
$200,000
U.S. Department of the Interior (National Park Service)
Federal

Application Deadline

Mar 31, 2025

Date Added

Jan 6, 2025

This grant provides financial assistance to various organizations and governments for projects that preserve and interpret historic battlefields and sites of armed conflict across the United States.

Recreation
State governments
SERDP/ESTCP Fire Equipment Challenge
$85,000
Strategic Environmental Research and Development Program (SERDP)
Federal

Application Deadline

Feb 28, 2025

Date Added

Feb 18, 2025

This grant encourages the development of innovative remote-operated technologies and autonomous vehicles to improve wildfire response on military lands, offering monetary prizes to participants from various sectors, including industry and academia.

Environment
County governments
Addressing Stigma to End the HIV Epidemic in the U.S.
$4,250,000
U.S. Department of Health & Human Services (Health Resources and Services Administration)
Federal

Application Deadline

Mar 18, 2025

Date Added

Jun 12, 2024

This funding opportunity provides financial support to nonprofit organizations and educational institutions to implement and evaluate anti-stigma interventions that improve access to HIV care and prevention services across the U.S.

Health
State governments
NIDCR Small Research Grants for Analyses of Existing Genomics Data (R03 Clinical Trial Not Allowed)
$100,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 7, 2025

Date Added

Mar 28, 2023

This funding opportunity supports small-scale research projects that analyze existing genomic data to advance understanding of dental, oral, and craniofacial health, particularly focusing on health disparities and biological pathways for intervention.

Health
State governments
Early- and Late-Stage Clinical Trials for the Spectrum of Alzheimer's Disease/Alzheimer's Disease-Related Dementias and Age-Related Cognitive Decline (R01 Clinical Trial Optional)
$20,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 17, 2024

Date Added

Jul 2, 2024

The "Early- and Late-Stage Clinical Trials for the Spectrum of Alzheimer's Disease/Alzheimer's Disease-Related Dementias and Age-Related Cognitive Decline" grant is a $20 million funding opportunity from the National Institutes of Health, aimed at supporting innovative clinical trials that develop and test pharmacological and non-pharmacological interventions for Alzheimer's disease and age-related cognitive decline over a five-year period.

Health
State governments
Translational Research Toward Development of a Kaposi Sarcoma Herpesvirus (KSHV) Vaccine (U01 Clinical Trial Optional)
$500,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Dec 4, 2024

Date Added

Oct 16, 2023

This grant provides funding for researchers to develop a vaccine against Kaposi sarcoma herpesvirus (KSHV), aiming to prevent infection and treat related diseases in affected populations.

Education
State governments
Naval Support Facility Indian Head Shoreline Restoration 4B6-1 2
$1,200,000
U.S. Department of Defense (NAVFAC Washington DC )
Federal

Application Deadline

Jun 23, 2025

Date Added

May 27, 2025

This funding opportunity is designed to support shoreline restoration projects at a military facility in Maryland, focusing on erosion control and habitat enhancement to improve water quality in the Chesapeake Bay.

Natural Resources
County governments
Rehabilitation Engineering Research Centers (RERC) Program: RERC on Rehabilitation Technologies for Children with Orthopedic Disabilities
$975,000
U.S. Department of Health & Human Services (Administration for Community Living)
Federal

Application Deadline

Apr 18, 2025

Date Added

Feb 21, 2025

This funding opportunity provides financial support for research and development of innovative rehabilitation technologies aimed at improving the independence and quality of life for children with orthopedic disabilities.

Science and Technology
State governments
Expanding Tribal Childrens Advocacy Centers
$700,000
U.S. Department of Justice (Office of Juvenile Justice Delinquency Prevention )
Federal

Application Deadline

Oct 27, 2025

Date Added

Sep 18, 2025

This funding opportunity provides financial support to Tribal governments and organizations to establish or improve children's advocacy centers that assist American Indian and Alaska Native communities in addressing child abuse and providing trauma-informed care.

Law Justice and Legal Services
Public and State controlled institutions of higher education
FY 2025 Community Safety Grant (CSG)
$500,000
U.S. Department of Transportation (Pipeline and HazardoU.S. Materials Safety Admin)
Federal

Application Deadline

Jun 20, 2025

Date Added

May 28, 2025

This funding opportunity provides financial support to nonprofit organizations for training and outreach initiatives that enhance community safety in response to hazardous materials transportation incidents.

Employment Labor and Training
Nonprofits
Addressing Development and Use of Chemical and Biological Weapons by Russia
$10,000,000
U.S. Department of State (Bureau of International Security-Nonproliferation)
Federal

Application Deadline

Jul 30, 2025

Date Added

Jun 2, 2025

This funding opportunity provides financial support to organizations working to prevent Russia from acquiring and using chemical and biological weapons through enhanced security measures, training, and international collaboration.

International Development
For profit organizations other than small businesses