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Grants for Nonprofits - Federal

Explore 5,566 grant opportunities

BJA FY25 DOJ Jails and Justice Support Center
$2,000,000
U.S. Department of Justice (Bureau of Justice Assistance)
Federal

Application Deadline

Mar 4, 2025

Date Added

Jan 13, 2025

This funding opportunity provides financial support to organizations that assist jails in improving safety, security, and operations while addressing challenges like high inmate turnover and mental health issues.

Law Justice and Legal Services
Public and State controlled institutions of higher education
Engineering Improved Stem Cell-Derived Islet Cells for Replacement Therapies (R01 - Clinical Trial Not Allowed)
$500,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 6, 2026

Date Added

Dec 4, 2025

This funding opportunity supports U.S.-based researchers and organizations working to improve stem cell-derived islet cells for treating type 1 diabetes through innovative engineering approaches.

Health
State governments
Aeif 2025
$30,000
U.S. Department of State (U.S. Mission to Guatemala)
Federal

Application Deadline

Jan 15, 2025

Date Added

Dec 4, 2024

This funding opportunity supports teams of alumni from U.S. government-sponsored exchange programs to implement innovative community projects in Guatemala that address issues like disaster resilience, migration, rule of law, economic growth, and civil society capacity building.

International Development
Nonprofits
High-efficiency Nitrogen Oxidation (HNO3)
Contact for amount
U.S. Department of Defense (DARPA - Defense Sciences Office)
Federal

Application Deadline

Feb 5, 2026

Date Added

Dec 2, 2025

This funding opportunity is designed for researchers and organizations developing innovative methods to produce nitric acid more efficiently and sustainably, reducing reliance on traditional ammonia-based processes.

Science and Technology
State governments
Impact of Comorbidities and Co-Infections on HIV Reservoirs (R01 Clinical Trial Not Allowed)
$2,800,000
U.S. Department of Health and Human Services - National Institutes of Health
Federal

Application Deadline

Jul 30, 2024

Date Added

Mar 1, 2024

This Notice of Funding Opportunity (NOFO) seeks to foster new multi-disciplinary teams to address how HIV Comorbidities and co-infections within the missions of NIDDK and NIAID interact with viral reservoirs, potentially confounding cure strategies aimed at either sustained viral suppression or elimination from the body. These teams will mechanistically interrogate the impact of inflammation, metabolic perturbations, or other pathophysiological processes associated with these comorbidities or co-infections on reservoir dynamics, and/or the interplay of these conditions and co-infections on HIV reservoir biology in ways that are likely to interact with potential cure strategies.

Food and Nutrition
State governments
DoD Multiple Sclerosis, Clinical Trial Award
$2,000,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Oct 7, 2024

Date Added

Apr 22, 2024

The "DoD Multiple Sclerosis, Clinical Trial Award" is a grant that funds the implementation of clinical trials aimed at significantly impacting the treatment or management of multiple sclerosis, ranging from small proof-of-concept trials to large-scale trials, with the expectation that the proposed trial will begin within 12 to 18 months after the award date.

Science and Technology
Nonprofits
Notice of Intent to Publish a Funding Opportunity Announcement for Intellectual and Developmental Disabilities Research Centers 2025 (P50 Clinical Trial Optional)
$18,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 15, 2025

Date Added

May 13, 2025

This funding opportunity is designed to support research centers that focus on improving the diagnosis, treatment, and prevention of intellectual and developmental disabilities through collaborative and interdisciplinary research efforts.

Health
State governments
FY25 COPS Blue Alert Program
$150,000
U.S. Department of Justice (Community Oriented Policing Services)
Federal

Application Deadline

Jun 24, 2025

Date Added

May 22, 2025

This funding opportunity provides financial support to various organizations and agencies to enhance the nationwide Blue Alert system, which helps protect law enforcement officers and improve public safety.

Law Justice and Legal Services
City or township governments
Rehabilitation Engineering Research Centers (RERC) Program: RERC on Universal Design Applications
$975,000
U.S. Department of Health & Human Services (Administration for Community Living)
Federal

Application Deadline

Mar 6, 2025

Date Added

Feb 21, 2025

This funding opportunity provides financial support for organizations to develop and evaluate innovative technologies and environments that promote accessibility and usability for individuals with disabilities.

Science and Technology
State governments
American Spaces Grant Funding 2024
$30,000
DOS-MAR (U.S. Mission to Morocco)
Federal

Application Deadline

May 17, 2024

Date Added

Apr 10, 2024

We are pleased to announce that U.S. Mission Morocco is considering proposals for American Spaces Support Funding ranging from $5,000 to $30,000 USD to carry out programming at one or both of Mission Moroccos two American Spaces. American Spaces serve as the primary cultural and information hubs established by the U.S. government abroad, offering free and open access to communities worldwide with an interest in gaining insights into the United States. In Morocco, there are two such spaces: Dar America, located in Casablanca, and the American Space Oujda (ASO), situated in Oujda. Dar America and the ASO have the responsibility of providing vibrant programming that fosters stability and prosperity in Morocco, all while engaging a wide range of audiences. The programming goals from the previous year encompassed the enhancement of soft skills, entrepreneurship, and climate change training. In the fiscal year 2023, the programming extended to over 332 virtual and in-person initiatives and events, drawing in up to 15,466 attendees, both virtually and in-person, across the two spaces. Please read this document carefully and follow all instructions. This notice is subject to the availability of funding. B. PROGRAM OBJECTIVES: For FY2024, American Spaces Morocco wish to continue to implement impactful programs focused on English language learning, digital transformation empowerment, soft skills development, STEAM training, countering disinformation, and environment and climate change awareness. Key Programming descriptions: Enhancing English Language Learning: Implement a comprehensive English Language Learning (ELL) program designed to empower individuals from diverse communities toacquire and improve their English language learning. The aim is to create an inclusive and immersive learning environment, addressing the linguistic needs of participants while fostering cultural understanding. Digital Transformation Empowerment: Provide individuals and small businesses with the knowledge, skills, and tools necessary to navigate the digital landscape, fostering innovation, economic growth, and digital inclusion. Professional Development for Moroccan Youth: Promote professional and soft skills development, entrepreneurship and innovation through mentoring and training to promote positive community engagement and increase employability. Science, Technology, Engineering, arts, and Math (STEAM) Programming: Create innovative STEAM programs to engage youth at Moroccos American Spaces while utilizing the existing Makerspaces. Environment and Climate Programming: Expand understanding of environmental and climate change challenges through engaging and hands-on programming. Countering Disinformation: Promote media literacy and other skills to help young people effectively identify online disinformation. The primary target audience is young Moroccans, aged 18 30 and the principal method of engagement will be through in-person programming at the American Spaces. Virtual engagement may be a part of the overall strategy, augmenting in-person programming, when possible, and acting as the primary method of engagement, when necessary. Preference will be given to proposals that prioritize and maximize the needs of the audience while limiting overhead, equipment, and other expenses that do not directly support program participants. A successful proposal will develop a robust monthly calendar of activities spanning at least eight months and directly address at least one of the six key programming areas. Prospective grantees may plan programming activities at one or both American Spaces. Please see below an example of a monthly calendar.See attached copy of the NOFO for full information.

Science and Technology
Nonprofits
OJJDP FY24 Court Appointed Special Advocates (CASA) Training, Technical Assistance, and Subgrants Program
$16,245,000
U.S. Department of Justice - Office of Juvenile Justice Delinquency Prevention
Federal

Application Deadline

Aug 1, 2024

Date Added

Jul 2, 2024

With this solicitation, OJJDP seeks to select organization(s) to carry out key activities designed to ensure abused and neglected children involved in dependency court proceedings have access to a court appointed special advocate.

Law Justice and Legal Services
Public and State controlled institutions of higher education
Senior Medicare Patrol State Project Grants - Michigan
$890,000
U.S. Department of Health & Human Services (Administration for Community Living)
Federal

Application Deadline

Mar 14, 2025

Date Added

Dec 9, 2024

This funding opportunity supports initiatives in Michigan that educate and assist Medicare beneficiaries in preventing and reporting healthcare fraud, particularly targeting those with the greatest economic and social needs.

Income Security and Social Services
State governments
Time-Sensitive Opportunities for Health Research (R61/R33 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 2, 2025

Date Added

Apr 25, 2024

This funding opportunity provides rapid financial support for researchers to study health outcomes related to urgent events like pandemics, natural disasters, or sudden policy changes, allowing them to gather critical data quickly.

Education
State governments
Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Human Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 26, 2025

Date Added

Dec 21, 2023

This grant provides funding for early stage investigators to pursue innovative and high-risk research projects involving human participants, without the need for preliminary data.

Education
State governments
Schizophrenia and related disorders during mid- to late-life (R21 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 8, 2025

Date Added

Jun 29, 2023

This funding opportunity supports innovative research aimed at understanding and improving treatment for schizophrenia and related disorders in individuals aged 35 and older.

Health
State governments
Rural Maternity and Obstetrics Management Strategies Program (Rural MOMS)
$1,000,000
U.S. Department of Health & Human Services (Health Resources and Services Administration)
Federal

Application Deadline

Apr 22, 2025

Date Added

Jul 15, 2024

This funding opportunity provides resources to rural health networks to improve access, coordination, and quality of essential health services for underserved populations in rural communities.

Health
State governments
National Center on Parent, Family and Community Engagement
$6,400,000
U.S. Department of Health & Human Services (Administration for Children and Families - OHS)
Federal

Application Deadline

Jun 2, 2025

Date Added

Jul 31, 2024

This funding opportunity provides $6.4 million to organizations that support family engagement and community partnerships in early childhood education, specifically targeting programs that assist children and families in Head Start and Early Head Start.

Income Security and Social Services
Special district governments
Monitoring Changes in Population Densities and Reproductive Success in Wading Bird Populations in the Florida Everglades for USACE Jacksonville District
$137,273
U.S. Department of Defense (Fort Worth District)
Federal

Application Deadline

Jul 27, 2025

Date Added

Jun 28, 2025

This funding opportunity is designed for organizations with expertise in ecology and wading bird monitoring to support the conservation and restoration efforts of the Florida Everglades through systematic population and reproductive success assessments.

Environment
Public and State controlled institutions of higher education
DoD Breast Cancer, Transformative Breast Cancer Consortium Award
$38,750,000
U.S. Department of Defense - Dept. of the Army -- U.S.AMRAA
Federal

Application Deadline

Aug 6, 2024

Date Added

Mar 26, 2024

The FY24 Transformative Breast Cancer Consortium Award is designed to support collaborations and ideas that will transform the lives of individuals with, and/or at risk for, breast cancer and will significantly accelerate progress toward ending breast cancer. Applicants must bring together different perspectives to develop new paradigms that will solve fundamental yet overarching problems in breast cancer. This award requires a team-based approach by a consortium of exceptional researchers and advocates, whose collaborative efforts will make a transformative impact in breast cancer. The transformation intended by the consortium must be in peoples lives, and not in the healthcare or research system.This funding opportunity is a separate mechanism from the Transformative Breast Cancer Consortium Development Award, which is intended to provide successful applicants the time and resources needed to bring investigators and breast cancer advocates together to establish a consortium framework and conduct preliminary research to support application to a future, full Transformative Breast Cancer Consortium Award (pending availability of funds). For FY24, investigators may be named as Consortium Director on an application submitted to either (but not both) of these mechanisms. It is not necessary to receive a development award in order to apply for the current funding opportunity or anticipated full consortium awards in the future. Detailed information on the FY24 Transformative Breast Cancer Consortium Development Award is available under a separate program announcement (HT942524BCRPTBCCDA).For the FY24 Transformative Breast Cancer Consortium Award, the consortium should have at least four, but no more than five, project teams, each investigating different projects under a central hypothesis. No more than two project teams may be based at one institution. Each teams work must be integrated within the consortium so that every component is working toward the consortiums central hypothesis. Note: This award is not intended to replace, supplement, duplicate, or compete with other collaborative research efforts, such as the National Cancer Institute (NCI) Specialized Programs of Research Excellence (SPOREs), and it should not represent a collection of related Program Project grants or subprojects.The proposed consortiums overall work is expected to be innovative. In addition, the Transformative Breast Cancer Consortium Award will include funds for seed projects to pursue brand-new, high-risk/high-reward concepts that arise from the work, during the award period.DOD FY24 Transformative Breast Cancer Consortium Award 5The Breast Cancer Landscape describes the reality of breast cancer and identifies overarching challenges to progress the field. Research funded under this award mechanism should result in answers that will fundamentally and significantly transform and disrupt the present landscape.Applications submitted to the Transformative Breast Cancer Consortium Award must include the following: Research that includes truly innovative and brand-new, paradigm-shifting work in breast cancer that will address vital issues in a unique way. The issues may be one (or more) of the FY24 BCRP Overarching Challenges or, with justification, may be a different issue that meets the intent of the award mechanism and addresses the mission of ending breast cancer. If the application identifies a different fundamental issue, it must be coupled with at least one of the FY24 BCRP Overarching Challenges. Research that includes different disciplines that come together to address ending breast cancer with an ecologic approach. The consortiums proposed research must look at all aspects of the disease and bring together these different perspectives into one overarching plan for a deep, definitive dive into the FY24 BCRP Overarching Challenge(s) or other fundamental issue identified in the application. The plan also should include issues related to the hypothesis that have not been previously addressed or answered. A plan that describes in detail the integration across the consortium in all aspects, including administration, logistics, and substance. Applications must describe the substantive integration across and among teams that are necessary for the work. The required communication plan and administrative management plan will not suffice to show integration, nor will identifying individual team members who will cross teams. A detailed explanation of the substantive research processes that will be integrated is required.Synergistic, highly integrated, multidisciplinary, and multi-institutional research teams of leading scientists, clinicians, and consumer advocates must be assembled into a consortium to address a major problem in a way that could not be accomplished by a single investigator or group. While the project teams are made up of different groups, each with its own Principal Investigator (PI), the teams must be working on the major problem identified in the Transformative Breast Cancer Consortium Award application and under the leadership of the Consortium Director. The research proposed in Transformative Breast Cancer Consortium Award applications may include phase 1 clinical trials and collaborations with pharmaceutical or biotechnology industry scientists and/or companies, as appropriate. However, a clinical trial is not required, and the primary thrust of the application should not be a clinical trial.Although not all-inclusive, applications that propose the following as the primary effort(s) or central hypothesis of the consortium will not meet the intent of this award mechanism: NCI Program Project or SPORE grants or applications Conducting drug screens or testing a cocktail of therapeutics Targeting a single gene or protein Developing a new derivative or formulation of an old drug Conducting genomic landscape mapping analyses Seeking to improve existing technologies (e.g., mammography or magnetic resonance imaging screening)All applications submitted to the Transformative Breast Cancer Consortium Award must address the following key features:1. IMPACTDemonstrate potential to transform or improve the lives of individuals with, and/or at risk for, breast cancer. The time to the final impact may vary, but the outcomes of the effort must be transformative and significantly advance the BCRPs mission of ending breast cancer. A clear and compelling presentation of how the effort will be transformative for individuals with, and/or at risk for, breast cancer must be provided. Applications proposing research that represents an incremental advance in breast cancer do not meet the intent of this award mechanism.2. INNOVATIONPursue innovative, high-risk/high-reward research that has the potential to change existing paradigms, or develop new paradigms. Innovative research may introduce a new paradigm, look at existing problems from new perspectives, or exhibit other highly creative qualities. In addition to the requirement that the consortiums overall research be innovative, applications must describe a plan to support the pursuit of innovative concepts through seed projects, i.e., the development of new concepts that emerge during the course of the award. These seed projects should enable the research team to explore new avenues of high-risk/high-reward ideas that were not part of the original application, but that develop during the project and are within the scope of the overall vision of the research. A portion of the total direct budget costs (no more than 5%) must be reserved to support the seed projects, and these funds may not be used for equipment or travel.3. CONSORTIUMIntegrate project teams consisting of preeminent investigators and advocates from appropriate disciplines and institutions. Applications should include a robust consortium of researchers with the combined backgrounds and breast cancer-related expertise to enable successful conduct of the proposed research. Emphasis must be placed on integrating the most highly qualified investigators and advocates to focus on the research problem, regardless of their location. These investigators must include highly accomplished scientists, clinicians, and promising young investigators in the targeted areas of research who collectively represent the best team to solve the problem(s) identified. The proposed research effort should be broad enough to require a multidisciplinary approach that is reflected in the composition of the consortium team. Inclusion of scientists from nontraditional disciplines is encouraged.The award mechanism is structured with a Consortium Director and at least three, but no more than four, Project Team PIs representing at least two institutions. The Consortium Director is responsible for the day-to-day management of the consortium, as well as for leading their own project team. The Consortium Director, together with the Project Team PIs, are jointly responsible for leading and executing the proposed research projects that are integrated into a central hypothesis and will result in answers that will fundamentally and significantly transform and disrupt the present breast cancer landscape. Please see the top of this section, Section II.B, Award Information, for more details.Incorporate breast cancer consumer advocates into every aspect of the proposed consortiums activities. Applications are required to include consumer advocate involvement. The consortium team must include at least one breast cancer consumer advocate per project team. The consumer advocates are expected to represent the perspective of the patient population(s) that are most relevant to the consortiums proposed research. Breast cancer consumer advocates must have an active role in every aspect of the proposed consortiums work including consortium conception and design, ongoing discussion, decisions and oversight, program evaluation, and dissemination of information to the public. Consumer advocates must be integrated into and play an active role in the leadership and decision-making committees for the consortium at each participating institution. Examples of appropriate integration include membership on the advisory board(s) and steering committee(s), participation in each project team, and attendance at all consortium-related meetings. As lay representatives, the consumer advocates must be individuals who have been diagnosed with breast cancer, they should be part of a breast cancer advocacy organization, and their role in the project should be independent of their employment. They cannot be employees of any of the institutions participating in the application. They must have a high level of familiarity and training involving science and current issues in breast cancer research.4. INTEGRATIONProvide a plan that describes in detail the integration across the consortium in all aspects, including administration, logistics, and substance. Applications must demonstrate the substantive integration across and among teams that are necessary for the work. The integration plan must provide a detailed explanation of the substantive research processes that will be integrated.5. IMPLEMENTATIONProvide a strategy for implementation. Projects must demonstrate solid scientific rationale, and applications must include published and/or preliminary data that support the feasibility of their hypotheses and/or approaches. The application must include a detailed research management plan that identifies critical milestones, outlines the innovations and technical solutions that will be implemented to accomplish the milestones, and explains how these solutions will ultimately be translated to individuals with, and/or at risk for, breast cancer. It is expected that the proposed plan will present an exceptional level of innovation and creativity.Accelerate research progress through communication. Communication between and among consortium team members is essential to the success of the consortium. Applications must include a strategy for sharing data in real time and using information technologies to facilitate timely and effective communication and cooperation. The communication plan should specify the processes and tools to be used for regular and structured communication. The consortium should take full advantage of state-of-the-art communication and data sharing tools in addition to formal and informal meetings. The framework for the communication plan must be part of the application and the individual(s) who will maintain the data sharing and communications technologies must be identified.Provide an effective, coordinated administrative management plan that integrates and optimizes the research and collaborations. The Consortium Director is required to commit a minimum level of time and effort of 25% to direct and manage an initiative of this magnitude, as well as lead their own project team. The Consortium Director must have the scientific ability and proven administrative ability to oversee large research programs and a proven record of leadership, including experience in the effective use of communication tools and the management of multifaceted and multidisciplinary projects. The administrative management plan must explain how the consortium will be organized and managed, and specify the processes and tools to be used for project meeting scheduling, reviews of research findings, ensuring multidisciplinary authorship of all publications arising from the consortiums work, and other issues of common concern to the consortium and its investigators. The administrative management plan also must describe procedures and processes that will be used to maximize the resources (e.g., databases, animal models) and products (e.g., antibodies) generated by the consortium and how these resources and products will be made available to the scientific community. A portion of the total direct budget costs must be reserved for a program manager.Award Structure: The Transformative Breast Cancer Consortium Award is structured to accommodate up to five PIs (the Consortium Director and three or four Project Team PIs). The Consortium Director will be responsible for the majority of the administrative tasks associated with application submission and the day-to-day management of the consortium. In addition, the Consortium Director will be responsible for leading their own project team. The Consortium Director and Project Team PIs each have different submission requirements; however, all PIs should contribute significantly to the development of the proposed research project, including the Project Narrative, Statement of Work (SOW), and other required components. If recommended for funding, each PI will be named on separate awards to the recipient organizations. For individual submission requirements for the Consortium Director and Project Team PIs, refer to Section II.D.2, Content and Form of the Application Submission.The Consortium Director, Project Team PIs, and consumer advocates will be required to present an update on progress toward accomplishing research milestones and goals of the consortium and each project at an annual In-Progress Review (IPR) Meeting for the Transformative Breast Cancer Consortium Award. The intent of the IPR Meeting is to assess research progress, address problems, and define future directions. Annual IPR Meetings will be held at the conclusion of year 1 and every subsequent year in the period of performance and will be attended by members of the BCRP Programmatic Panel, CDMRP staff, and the USAMRAA Grants Officer to facilitate oversight and provide feedback to the consortium. IPR Meetings will either be held in person in the National Capital Region or virtually, at the discretion of the government. Continued funding may be contingent upon the successful completion of specific research milestones and goals. Research milestones from the approved SOW will be determined during the award negotiation process.In addition to IPR Meetings, each consortium must hold biannual workshops, which may be held at the PIs institutions or virtually, to facilitate ongoing communication and exchange of information within the consortium, as well as with advisory board(s) and/or steering committee(s).

Science and Technology
Nonprofits
Community Agriculture Grants (Wisconsin)
$250,000
USDA-NRCS (Natural Resources Conservation Service)
Federal

Application Deadline

May 22, 2024

Date Added

Mar 22, 2024

This Notice of Funding Opportunity (NFO) is being released prior to appropriation and/or apportionment of funds for fiscal year 2024. Enactment of additional continuing resolutions or an appropriations act may affect the availability or level of funding for this program. The purpose of this NFO is to encourage and promote conservation planning and conservation practice implementation in urban, suburban, and other small-scale type agricultural operations. Emphasis will be placed on projects that establish new demonstration community gardens, or enhance and expand existing community agriculture projects. Proposals should seek to: 1. Provide conservation learning experiences to urban, suburban, and Tribal communities. 2. Address concerns regarding food deserts. 3. Advance Tribal food sovereignty. 4. Achieve positive and measurable natural resources conservation outcomes. For new users of Grants.gov, see Section D. of the full Notice of Funding Opportunity for information about steps required before submitting an application via Grants.gov. Key Dates Applicants must submit their applications via Grants.gov by 11:59 pm Eastern Time on May 22, 2024. For technical issues with Grants.gov, contact Grants.gov Applicant Support at 1-800-518-4726 or [email protected]. Awarding agency staff cannot support applicants regarding Grants.gov accounts. For inquiries specific to the content of the NFO requirements, contact the federal awarding agency contact (section G of this NFO). Please limit questions to those regarding specific information contained in this NFO (such as dates, page numbers, clarification of discrepancies, etc.). Questions related to eligibility or the merits of a specific proposal will not be addressed. The agency anticipates making selections by June 21, 2024 and expects to execute awards by September 1, 2024. These dates are estimates and are subject to change.

Agriculture
State governments