Grants for Nonprofits - Federal

The "NIA Renewal and Competing Revision Cooperative Agreements in Aging Research" grant is a funding opportunity for the renewal and revision of existing U01 research projects related to aging, including areas such as genetics, biology, neuroscience, clinical studies, and Alzheimer's disease, with the requirement that applicants integrate their systems with the Clinical Research Operations Management System (CROMS) for data management.

The Era of Hope Scholar Award supports individuals early in their careers who have demonstrated significant potential to effect meaningful change in breast cancer. These individuals should be exceptionally talented scientists who have shown that they are the best and brightest in their field(s) through extraordinary creativity, vision, innovation, and productivity. They should have demonstrated experience in forming effective partnerships and collaborations and must exhibit strong potential for future leadership in breast cancer research.As the intent of the Era of Hope Scholar Award is to recognize creative and innovative individuals rather than projects, the central features of the award are the demonstrated ability of the individual named as the Principal Investigator (PI) in the application to go beyond conventional thinking in their field and the innovative contribution that the PI can make toward ending breast cancer. The application should articulate a vision that challenges current dogma and demonstrates an ability to look beyond tradition and convention.Experience in breast cancer research is not required; however, the application must focus on breast cancer, and the PI must commit a minimum of 25% level of time and effort during the period of performance to conduct breast cancer research under this award. Individuals from other disciplines who apply novel concepts to breast cancer are encouraged to submit.The PI is encouraged to assemble a research team that will provide the necessary expertise and collaborative efforts toward accomplishing the research goals. The PIs research team must include two or more breast cancer consumer advocates. As lay representatives, the consumer advocates must be individuals who have been diagnosed with breast cancer and are actively involved in a breast cancer advocacy organization. Their role should be independent of their employment, and they may not be employees of any organizations participating in the application. The consumer advocates should have a high level of knowledge of current breast cancer issues and the appropriate background and/or training in breast cancer research to contribute to the project. Their role should be focused on providing objective input throughout the research effort and its potential impact for individuals with, or at risk for, breast cancer.A congressionally mandated Metastatic Cancer Task Force was formed with the purpose of identifying ways to help accelerate clinical and translational research aimed at extending the lives of advanced state and recurrent patients. As a member of the Metastatic Cancer Task Force, the CDMRP encourages applicants to review the recommendations (https://health.mil/Reference-Center/Congressional-Testimonies/2018/05/03/Metastatic-Cancer-Research) and submit research ideas to address these recommendations provided they are within the limitations of this funding opportunity and fit within the FY24 BCRP priorities.Innovative research involving nuclear medicine and related techniques to support early diagnosis, more effective treatment, and improved health outcomes of active-duty Service Members and their Families is encouraged. Such research could improve diagnostic and targeted treatment capabilities through noninvasive techniques and may drive the development of precision imaging and advanced targeted therapies.The CDMRP encourages research on health areas and conditions that affect women uniquely, disproportionately, or differently from men, including studies analyzing sex as a biological variable. Such research should relate anticipated project findings to improvements in women’s health outcomes and/or advancing knowledge for women’s health.The proposed research must be relevant to active-duty Service Members, Veterans, military beneficiaries, and/or the American public. Collaborations between researchers at military or Veteran institutions and non-military institutions are strongly encouraged. These relationships can leverage knowledge, infrastructure, and access to unique clinical populations that the partners bring to the research effort, ultimately advancing cancer research that is of significance to the Warfighter, military Families, and the American public.Clinical trials are allowed. A clinical trial is defined in the Code of Federal Regulations, Title 45, Part 46.102 (45 CFR 46.102) as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include a placebo or another control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes.Studies that do not seek to measure safety, effectiveness, and/or efficacy outcome(s) of an intervention are not considered clinical trials.For the purposes of this funding opportunity, research that meets the definition of a clinical trial is distinct from clinical research. Clinical research encompasses research with human data, human specimens, and/or interaction with human subjects. Clinical research is observational in nature and includes:(1) Research conducted with human subjects and/or material of human origin such as data, specimens, and cognitive phenomena for which an investigator (or co-investigator) does not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention. Research meeting this definition may include but is not limited to: (a) mechanisms of human disease, (b) diagnostic or detection studies (e.g., biomarker or imaging), (c) health disparity studies, and (d) development of new technologies.(2) Epidemiologic and behavioral studies that do not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention.(3) Outcomes research and health services research that do not fit under the definition of clinical trial.Excluded from the definition of clinical research are in vitro studies that utilize human data or specimens that cannot be linked to a living individual and meet the requirements for exemption under 46.104(d)(4) of the Common Rule.The funding instrument for awards made under the program announcement will be grants (31 USC 6304).The anticipated direct costs budgeted for the entire period of performance for an FY24 Era of Hope Scholar Award should not exceed $3.5M. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.Awards supported with FY24 funds will be made no later than September 30, 2025.The CDMRP expects to allot approximately $5.4M to fund approximately one Era of Hope Scholar Award application. Funding of applications received is contingent upon the availability of federal funds for this program, the number of applications received, the quality and merit of the applications as evaluated by peer and programmatic review, and the requirements of the government. Funds to be obligated on any award resulting from this funding opportunity will be available for use for a limited time period based on the fiscal year of the funds. It is anticipated that awards made from this FY24 funding opportunity will be funded with FY24 funds, which will expire for use on September 30, 2030.

This funding opportunity provides financial support to public and nonprofit organizations that deliver essential primary health care services to underserved communities across the U.S., ensuring access regardless of patients' ability to pay.

HRSA-25-002, HRSA-25-003, and HRSA-25-004 announces the opportunity to apply for funding under Ryan White HIV/AIDS Program (RWHAP) Part C Early Intervention Services (EIS) Program: Existing Geographic Service Areas. The purpose of this program is to provide comprehensive primary health care and support services in an outpatient setting for low-income people with HIV. Under this announcement, successful applicants must provide: (1) counseling for individuals with respect to HIV; (2) targeted HIV testing; (3) periodic medical evaluations of individuals with HIV and clinical and diagnostic services for HIV care and treatment; (4) therapeutic measures for preventing and treating the deterioration of the immune system, and for preventing and treating conditions arising from HIV; and (5) referrals for people with HIV to appropriate providers of health care and support services. These services are to be provided directly or through referrals, contracts, or memoranda of understanding (MOUs). This competition is open to current RWHAP Part C EIS recipients and new organizations proposing to provide RWHAP Part C EIS funded services in the geographic service areas listed in Appendix C. Please note that there are 3 funding announcement numbers included in this document with 3 different periods of performance (See Appendix C). If you are applying for more than one service area, you must submit a separate application for each proposed service area. All allowable services must relate to HIV diagnosis, care, and support, and must adhere to established HIV clinical practice standards consistent with U.S. Department of Health and Human Services (HHS) Guidelines. Please refer to the HIV/AIDS Bureau (HAB) Policy Clarification Notice (PCN) 16-02 Ryan White HIV/AIDS Program Services for a list of RWHAP allowable core medical and support services and their descriptions. According to the RWHAP Part C statute: At least 50 percent of the amount received under the award must be expended on EIS costs (except counseling and referrals/linkage to care); At least 75 percent of the award (after reserving amounts for administrative costs, planning/evaluation, and clinical quality management (CQM)) must be expended on core medical services costs (Please note: EIS is a subset of this 75 percent of the award) and; Not more than 10 percent of the total RWHAP Part C award funds can be expended on administrative costs. Applicants seeking a waiver to the core medical services requirement must submit a waiver request with this application as Attachment 15. For more details, see Program Requirements and Expectations.

This funding opportunity provides financial support for engineering studies to develop infrastructure for transporting captured carbon dioxide, targeting private companies, governments, non-profits, and educational institutions committed to reducing greenhouse gas emissions and promoting community benefits.

This funding opportunity provides financial support for agricultural development projects in developing countries and emerging democracies, focusing on increasing productivity and trade through the monetization of U.S. agricultural commodities.

The Public Diplomacy Section (PD) of the U.S. Embassy in Luxembourg, U.S. Department of State, announces an open competition for organizations to submit applications to carry out programs strengthening bilateral ties between the United States and Luxembourg on Bolstering Security and Defense. The U.S. Embassy Luxembourg invites proposals from non-governmental organizations, think tanks, government institutions, academic institutions, and individuals for programs strengthening the bilateral ties between the United States and Luxembourg and supporting Bolstering Security and Defense, including, but not limited to: Programs that raise awareness and increase support for U.S.-Luxembourg defense cooperation, with an emphasis on NATO, defense spending, and defense modernization; Programs to counter disinformation, misinformation, and malign influence as threats to democracy as well as those that promote and improve media literacy in Luxembourg; Programs that raise awareness and support for increased information sharing and cooperation in law enforcement and intelligence, with an emphasis on cyber security and countering ideologically motivated violent extremism; Projects that support addressing global challenges through building strong global alliances, for example through: NATO, the United Nations, and other multi-lateral institutions and forums. All programs must engage Luxembourg audiences. All programs must include a U.S. element or connection with U.S. experts that will promote increased understanding of U.S. policy and perspectives. Any speaker paid with grant funding must hold U.S. citizenship. Please review the complete NOFO on the Funding Opportunities page on our website: https://lu.usembassy.gov/grants-program/ or in the related documents tab on the announcement on grants.gov .

This grant provides funding to improve state capabilities in collecting and managing financial data related to special education services for children and youth with disabilities.

Research shows that HIV care must increasingly address the management of individuals with multiple coexisting diseases (p.357) such as infectious and chronic diseases, mental health and behavioral disorders, food insecurity, substance use, etc. Since individual diseases do not exist in a vacuum, neither does the management, or burden of disease on community well-being. In response, syndemic theory and approaches are used to (1) increase the focus on co-occurring and interacting disease and social conditions that exacerbate health inequities, and (2) advance the evidence base for effective approaches to assess, monitor, and intervene with respect to these co-occurring and interacting factors for optimal outcomes in HIV treatment and care. The purpose of this project is to design, implement, and evaluate innovative comprehensive interventions part of an integrated treatment plan , using a syndemic approach to address co-occurring and interacting conditions of HIV, substance use disorder, intimate partner violence (IPV), and other social determinants of health that impact health outcomes of racial and ethnic minorities with HIV.

Each funding opportunity description is a synopsis of information in the Federal Register application notice. For specific information about eligibility, please see the official application notice. The official version of this document is the document published in the Federal Register. Free Internet access to the official edition of the Federal Register and the Code of Federal Regulations is available on GPO Access at: http://www.access.gpo.gov/nara/index.html. Please review the official application notice for pre-application and application requirements, application submission information, performance measures, priorities and program contact information. For the addresses for obtaining and submitting an application, please refer to our Revised Common Instructions for Applicants to Department of Education Discretionary Grant Programs, published in the Federal Register on December 7, 2022. Purpose of Program: In awarding research grants, the Institute of Education Sciences (IES) intends to provide national leadership in expanding knowledge and understanding of (1) education outcomes for all learners from early childhood education through postsecondary and adult education, and (2) employment and wage outcomes when relevant (such as for those engaged in career and technical, postsecondary, or adult education). The IES research grant programs are designed to provide interested individuals and the general public with reliable and valid information about education practices that support learning and improve academic achievement and access to education opportunities for all learners. These interested individuals include parents, educators, learners, researchers, and policymakers. In carrying out its grant programs, IES provides support for programs of research in areas of demonstrated national need. Assistance Listing Numbers: 84.305J and 84.305N. Assistance Listing Number (ALN) 84.305J.

The DoD Traumatic Brain Injury and Psychological Health, Translational Research Award aims to fund research that accelerates the application of findings in psychological health and traumatic brain injury into clinical practice, leading to the development of healthcare products, technologies, or clinical practice guidelines that improve patient outcomes.

The purpose of the NCCC program is to provide rapid, expert, and culturally competent clinical consultation and advice to health care team members on a wide range of HIV and HIV-related topics. The NCCC, using a combination of various funding sources, provides services through telephone-based warmlines, a hotline, and internet-based educational consultation services in the following clinical areas: General HIV prevention, care, and treatment, including diagnosis, testing, and antiretroviral therapy. Pre-exposure prophylaxis (PrEP). Post-exposure prophylaxis (PEP). Treatment and management of Hepatitis B and C and HIV coinfections. Treatment and management of substance use disorders in people with or at risk for HIV. Perinatal HIV care and management. The NCCC provides expert consultation that demonstrates an understanding of the HIV epidemic in a variety of locations including: EHE jurisdictions. Rural areas. Areas disproportionately impacted by substance use disorders including opioid use disorder, and other co-morbidities. Communities where a large number of the people with HIV identify as a non-white racial or ethnic group. The goals for the NCCC align with those of the RWHAP Part F AETC Program, which are: Goal 1: Expand the number of health care team members providing HIV care and prevention services, including providers with different backgrounds or experiences. Goal 2: Expand the ability of health care team members to provide effective HIV care and prevention services. Goal 3: Improve health equity by integrating HIV care and prevention in primary care and other health care settings that provide services to underserved populations. Goal 4: Enhance the capacity of the AETC Program to train health care team members to serve people at risk for or with HIV.

This grant provides funding to organizations that help victims of domestic violence and their pets by offering shelter, housing assistance, and related services.

Each funding opportunity description is a synopsis of information in the Federal Register application notice. For specific information about eligibility, please see the official application notice. The official version of this document is the document published in the Federal Register. Free Internet access to the official edition of the Federal Register and the Code of Federal Regulations is available on GPO Access at: http://www.access.gpo.gov/nara/index.html. Please review the official application notice for pre-application and application requirements, application submission information, performance measures, priorities and program contact information. For the addresses for obtaining and submitting an application, please refer to our Revised Common Instructions for Applicants to Department of Education Discretionary Grant Programs, published in the Federal Register on December 7, 2022. Purpose of Program: The purpose of the Technical Assistance on State Data Collection program is to improve the capacity of States to meet IDEA data collection and reporting requirements. Funding for the program is authorized under section 611(c)(1) of the Individuals with Disabilities Education Act (IDEA), which gives the Secretary authority to reserve not more than one-half of one percent of the amounts appropriated under Part B for each fiscal year to provide TA activities, where needed, to improve the capacity of States to meet the data collection and reporting requirements under Parts B and C of IDEA. The maximum amount the Secretary may reserve under this set-aside for any fiscal year is $25,000,000, cumulatively adjusted by the rate of inflation. Section 616(i) of IDEA requires the Secretary to review the data collection and analysis capacity of States to ensure that data and information determined necessary for implementation of sections 616 and 642 of IDEA are collected, analyzed, and accurately reported to the Secretary. It also requires the Secretary to provide TA, where needed, to improve the capacity of States to meet the data collection requirements, which include the data collection and reporting requirements in sections 616 and 618 of IDEA. In addition, the Further Consolidated Appropriations Act, 2024, Public Law 118-47, gives the Secretary authority to use funds reserved under section 611(c) of IDEA to administer and carry out other services and activities to improve data collection, coordination, quality, and use under Parts B and C of the IDEA. Further Consolidated Appropriations Act, 2024, Public Law 118-47, Div. D, Title III, 138 Stat. 460, 685 (2024). Assistance Listing Number: 84.373Z. Assistance Listing Number (ALN) 84.373Z.

This grant provides funding to organizations that will deliver training and support to improve early childhood education and development practices for children from birth to age five in Head Start and Early Head Start programs.

The U.S. Department of State, Bureau of Oceans and International Environmental and Scientific Affairs (OES) announces an open competition (see eligibility information in Funding Announcement), under the Toxic Chemicals earmark to reduce and mitigate environmental contamination and human exposures to lead by supporting capacity-building efforts for environmentally sound end-of-life management of lead-acid batteries (LABs) and used lead-acid batteries (ULABs) in Africa. This program aims to reduce lead pollution as well as promote and advance environmentally sustainable consumption and production at international, national, and subnational levels.

This funding opportunity is designed to support clinical centers conducting research on the development of Type 1 diabetes following episodes of acute pancreatitis, focusing on understanding its causes, progression, and risk factors in a diverse population.

This funding opportunity provides financial support for innovative projects aimed at reducing human trafficking globally, particularly in countries with significant trafficking challenges, through research-driven interventions and sustainable solutions.

This funding opportunity provides financial support to organizations that will help improve diabetes prevention and management for underserved populations by offering expertise, training, and resources to enhance health equity.

The Catalyze Product Definition Funding Opportunity Announcement (FOA) offers early-stage financial support for the discovery and study of potential treatments for heart, lung, blood, and sleep diseases, with the goal of progressing these projects to a stage where they qualify for the NHLBI Catalyze Preclinical program or secure funding from other sources for further development.