Grants for Nonprofits - Federal

This initiative will support innovative, collaborative, and multi-disciplinary research designed to study the effective adaptation, integration, and implementation of recommended guidelines of care of persons with multiple chronic conditions (MCCs) from populations that experience health disparities. Projects would be expected to involve more than one component and/or more than one level of influence within existing or newly proposed health care models. The ultimate goal of this initiative is attainment of optimal treatment and health outcomes goals in order to move towards health equity.

OVC seeks field-generated proposals that offer innovative solutions that will increase access to victim services and expand the options available to crime victims, especially in underserved communities. This solicitation encourages prospective applicants to partner with nontraditional partners that may not be typically associated with the victim services field.

This grant provides financial support and resources to early-career faculty from underrepresented backgrounds in neuroscience, helping them establish independent research careers through mentorship and protected research time.

This ISO seeks solution summaries and proposals for projects that fall within the general scope of the ARPA-H Scalable Solutions mission office. SSO expands what is technically possible by developing approaches that will leverage an interdisciplinary approach and collaborative networks to address challenges of geography, distribution, manufacturing, data and information, thereby improving health care access and affordability. In the United States, many communities and remote areas lack access to timely and quality health care, which leads to disparities in health outcomes for those populations. Bottlenecks during the manufacturing processes of products and health technologies also lead to delays and limited availability, preventing effective distribution of health care solutions to areas of need, especially in emergencies.ARPA-H SSO seeks solutions to improve the scalability and affordability of health care solutions, bridge gaps in underserved areas, and extend remote access to expertise by developing location-specific interventions, telemedicine solutions, and mobile health clinics. Solutions should focus on rapid innovation and the use of partnerships, as well as flexible distribution networks and streamlined manufacturing processes. The following SSO interest areas categorize the ground-breaking solutions we seek to support:Scalable Technologies and Interventions: Approaches to improve affordability and equitable access to health care that are adaptable to various geographic, demographic, economic contexts and can be rapidly deployed at scale (e.g., drug-repurposing*, telemedicine, point-of-care diagnostics, and modular health care infrastructure). Tailored solutions for the pediatric population that provide parity in access to treatments and other health care interventions with the adult population and adapt to the pediatric patients changing physiology and developmental status over the course of years. Transformational approaches to reduce or eliminate health disparities, including tools and models for product design and care delivery that scale novel approaches in human factors and human-centered design to respond to full diversity of patients. Tools to enable the scaling of provider and institutional capabilities (e.g., school nurses and schools, walk-in clinics, homesteading care) to address unmet health care access needs and expand availability of critical services. Foundational capabilities to accelerate diagnoses and reduce the cost of treatments for rare diseases wherever patients are, without the need for specialized facilities or healthcare expertise.* Solution summaries and proposals that focus on testing drugs for effectiveness for other disease states or use cases, are unlikely to be funded unless including additional R, or providing gains in cost reduction, accessibility, and/or equity.Collaborative Distribution Networks: Methods for standardization, automation, and democratization of complex procedures 5 including, but not limited to, histopathology, rare disease diagnosis and treatment, and surgical interventions to ensure access and delivery to populations diverse in demographics, geographies, and resources at scale. Approaches to enhance delivery of effective healthcare solutions in rural or low resource settings, including but not limited to "last mile delivery, at-home monitoring, imaging, drug delivery, telehealth augmentation, and support for remote medical procedures with limited need for specialized training. Technologies to enable the deployment of critical healthcare resources rapidly, equitably, and securely at scale to the point of need in permissive and non-permissive (i.e., damaged infrastructure, cyber-denied) environments during a public health crisis or natural disaster. Solutions to scale education and training of critical healthcare resources for health care providers and patients to ensure information integrity to prevent negative impacts to resource use/uptake. Innovative information technology, data and analytic products and technologies to enable ordering, inventory management, situational awareness, allocation planning and demand forecasting of critical healthcare resources during a public health crisis or natural disaster.Biomanufacturing Innovations*: Innovative manufacturing technologies and approaches that reduce cost, shorten the timeline for production, advance domestic competitiveness and reduce supply chain risk of biologics, cellular and gene therapies, pharmaceuticals, medical devices and personal protective equipment. New approaches to support predictable, programable biological production of conventional and novel materials reliability at scale in a cost-effective sustainable manner. Novel solutions to reduce the reliance on specialized handling and cold chain management of pharmaceuticals and biologics. Scalable innovations to advance and strengthen biomanufacturing supply chain and resolve bottlenecks including:o Advances in production of active pharmaceutical ingredients, process consumables, and other critical materials (i.e., enzymes, cell lines, etc);o Novel biomanufacturing-related data products, technologies or models to integrate into supply chain situational awareness systems;o Alternative materials and new manufacturing capabilities for personal protective equipment; ando Improvement of capabilities sustainably re-shore manufacturing and utilize a broad array of readily accessible and cost-efficient feedstocks as part of strengthening the local and national industry base. Analytics and novel sensor systems to precisely manage bioproduction, real-time release assays, and predictive capabilities to inform tuning of biological chassis for efficient and effective scale-up of manufacturing to industrial scale.*ARPA-H is not interested in approaches that merely increase capacity reservation.Other high-quality submissions that propose revolutionary technologies that meet the goals of SSO will be considered even if they do not address the topics listed above.Proposals are expected to use innovative approaches to enable revolutionary advances in medicine and healthcare, and the science and technology underlying these areas. While approaches that are disease agnostic are encouraged, ARPA-H welcomes proposals that bring radically new insights to address specific diseases including, but not limited to, cancer, diabetes, neurological diseases, pediatric and maternal/fetal health, infectious diseases, and cardiovascular disease.Specifically excluded are proposals that represent an evolutionary or incremental advance in the current state of the art or technology that has reached the clinical trial stage. An example of this type of proposal might include the request to fund clinical trials of an otherwise developed product. Additionally, proposals directed towards policy changes, traditional education and training, or center coordination, formation, or development, and construction of physical infrastructure are outside the scope of the ARPA-H mission.

Cooperative agreements under the Alzheimer's Disease Program Initiative (ADPI) Notice of Funding Opportunity (NOFO), are intended to support and promote the development and expansion of dementia-capable home and community-based service (HCBS) systems in States and Communities. There are two application options contained in this single NOFO: Grants to States (Option A) and Grants to Communities (Option B). No entity is eligible to apply for both State and Community options and no entity is eligible to hold more than one ADPI grant at a time. The dementia-capable systems resulting from program activities under either option are expected to provide quality, person-centered services and supports that help individuals living with dementia and their caregiver remain independent and safe in their communities.OPTION A: Grants to StatesApplicants for Option A (36 month cooperative agreements) are the governmental entities within states and territories designated as the state agency for dementia-capability and that have working relationships with their state agencies that enable creating and sustaining a dementia- capable HCBS System. Option A has two required objectives, the first of which is the creation, expansion and sustainability of a dementia-capable state HCBS system that includes Single Entry Point/No Wrong Door (SEP/NWD) access for people with dementia and their family caregivers. The second objective is to ensure access to a comprehensive, sustainable set of quality state HCBS that are dementia-capable and provide innovative services to the population with dementia and their caregivers.States and territories eligible for Option A are those that do not have active ACL ADPI State dementia-capability grants. All states without active grants are eligible to apply, however those states that have not benefited from ADSSP grants since before 2014 will be given priority consideration in the post-review decision-making process.OPTION B: Grants to CommunitiesCooperative agreements under Option B (36 month cooperative agreements) are available to private and/or public community-based organizations (CBO) that are able to: 1) demonstrate their operation within an existing dementia-capable HCBS system dedicated to the population that they serve; and 2) articulate opportunities and additional services in the targeted gap areas that would enhance and strengthen the existing system.Option B cooperative agreements are designed to aid community-based HCBS providers in addressing three specific service gaps in existing dementia-capable HCBS systems for persons living with or those at high risk of developing Alzheimers disease and related dementias (ADRD) and their caregivers.Option B applicants must address each of the following three gap areas:Provision of effective supportive services to persons living alone with ADRD in the community;Improvement of the quality and effectiveness of programs and services dedicated to individuals aging with intellectual and developmental disabilities with ADRD or those at high risk of developing ADRD; and Delivery of behavioral symptom management training and expert consultations for family caregivers.Community-based organizations are only eligible to hold one ADPI grant at a time. All community-based organizations without active ADPI grants are eligible to apply, however those that have not benefited from ADI-SSS and ADPI grant programs since before 2014 will be given priority consideration in the post-review decision-making process.

This funding opportunity supports partnerships that enhance research and education in astronomy and astrophysics, particularly for institutions serving historically underrepresented groups, by providing authentic research experiences and fostering an inclusive environment.

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on: (1) Courses for Skills Development; and (2) Develop and implement a program to prepare nurse scientists, and scientists in aligned fields, to conduct research on the social determinants of health in alignment with the NINR Strategic Plan.

This funding opportunity supports U.S.-based researchers and institutions in studying carbon dynamics to improve understanding of their effects on ecosystems and climate change.

This grant provides funding to U.S. and Cabo Verdean non-profit organizations and educational institutions for projects that promote cultural exchange, democratic governance, and economic growth between the United States and Cabo Verde.

The purpose of this NIDCD initiative is to encourage research in the development, characterization, and reproducibility/reliability of human auditory and vestibular organoids.Applications investigating animal organoids are allowable but only if accompanying comparative or other integrated companion studies with human organoids. Singular animal organoid studies alone are not responsive to this funding opportunity. This funding opportunity encourages innovative, reproducible, and novel methodologies and technologies that will drive the reproducibility and holistic longevity of hearing/balance sensory organoids as model systems. The development of novel tools to deliver genes, proteins, molecules, and synthetics that might lead to the successful expansion and longer-term survivability of organoid populations in a stable, reliable, and reproducible manner is highly encouraged. Subsequent characterization of the organoid platforms must be shown to mimic and recapitulate the native correlative biological function. Applications that provide approaches that remove current barriers and lessen challenges to improve current reproducibility and stability are highly encouraged. Applications that have breakthrough approaches and technologies using human auditory/vestibular organoids are highly encouraged.

The GEL-ICS program will build a cohesive group of leaders working on issues in cyberspace who are committed to the UN-affirmed Framework of Responsible State Behavior and will be equipped with the necessary knowledge and global connections to be effective advocates and champions of the Framework through the fellowship and other activities.

This funding opportunity supports organizations and tribal governments in providing essential reentry services to help formerly incarcerated individuals successfully reintegrate into their communities and reduce the risk of reoffending.

This funding opportunity supports research aimed at understanding how beliefs about cancer treatment outcomes influence symptom management, particularly focusing on underrepresented populations in biomedical research.

The Digital Projects for the Public program supports projects that interpret and analyze humanities content in primarily digital platforms and formats, such as websites, mobile applications and tours, interactive touch screens and kiosks, games, and virtual environments. The Digital Projects for the Public program supports projects that interpret and analyze humanities content in primarily digital platforms and formats, such as websites, mobile applications and tours, interactive touch screens and kiosks, games, and virtual environments. All projects should demonstrate the potential to attract a broad, general, nonspecialist audience, either online or in person at venues such as museums, libraries, or other cultural institutions. Applicants may also choose to identify particular communities and groups, including students, to whom a project may have particular appeal.

This funding opportunity provides financial support to nonprofit organizations, including tribal entities, to deliver training and technical assistance that improves access to safe drinking water and effective wastewater treatment in low-income rural communities across multiple states.

Fishers Ecological Knowledge (FEK) provides a rich and untapped source of information that can be used to inform BOEMs decisions regarding offshore wind; however, FEK has been vastly underutilized. The objective of this study is to collect FEK to improve BOEMs understanding of the use of the Gulf of Maine for fishing and the importance of fishing to the regional economy. BOEM will partner with the Responsible Offshore Science Alliance, and potentially with other interested organizations, to conduct this study.This study will identify local fishing communities willing to provide FEK and conduct interviews and workshops to collect the information. Importantly, the study will establish and execute clear methods for documenting, validating, and analyzing FEK. Collected data will be synthesized in an acceptable format (i.e., GIS and report documentation) to ensure the information can be incorporated into planning and resource management decisions.Additional planned tasks to be completed as part of the study include participatory mapping of fishing grounds, providing user guidance on spatial data tools like Marine Cadastre and the regional ocean portals, and providing regular updates to fishers regarding the spatial planning process and data needs in the Gulf of Maine. This effort must consider data confidentiality to ensure that fishing community information collected for this study are not misused. Such measures will be very important to instill confidence among fishers to accurately collect FEK.

This Funding Opportunity Announcement (FOA) seeks innovative grant applications in nonmalignant hematology research that will steer the field in new directions. Applications to this FOA should propose proof of principle research that is tightly focused into one specific aim, which can be accomplished within a 1-3 year project period, and is directed at validating novel concepts and approaches that promise to open new pathways for discovery.The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the National Heart, Lung, and Blood Institute (NHLBI), and the National Institute on Aging (NIA) have joined together to build research activities in nonmalignant hematology. This Funding Opportunity Announcement (FOA) is intended to promote innovative research projects in nonmalignant hematology that explore high impact and new directions of inquiry. While each Institute shares interests in nonmalignant hematology research, they also bring different perspectives, thereby expanding the scope of the SHINE II program beyond a single Institute's research mission. This "New Directions in Hematology Research (SHINE-II)" program invites investigator-initiated grant applications for basic or early translational, proof of principle research projects that are tightly focused and directed at validating novel concepts and approaches that promise to advance new pathways for discovery. This program may include clinical research involving human subjects that is directed at understanding disease pathogenesis and prognosis. Research applications submitted under this FOA should be more limited in scope (single aim with sub-aims, as appropriate) and duration (1-3 years) than typical R01 grant applications. The SHINE-II FOA seeks specifically to promote and support new directions of research in their early stages. Applications submitted to this FOA should include preliminary data that support the conceptual basis of the research proposed and the technical approaches to be used. Moreover, while research applications submitted under this FOA are expected to be more limited in scope and shorter in duration than typical R01 applications, achievement of the research objective(s) proposed should validate novel pathways of discovery and provide the basis for future high impact research endeavors. Principal areas of interest for this collaborative FOA include: (1) hematopoietic stem cell biology, (2) lineage fate determinants, (3) aging-related immune dysfunction and lymphocyte biology, (4) myeloid cell biology, and myelopoiesis, (5) platelet biology and dysfunction, (6) erythroid cell biology and erythropoiesis, (7) the molecular biology of heme and hemoglobin, (8) acquired and congenital disorders of red blood cell production and survival leading to chronic anemia or bone marrow failure, (9) and the uptake, utilization, storage, and transport of iron in health and disease. Inquiries to Scientific/Research staff prior to submission of an application to this FOA are strongly encouraged to discuss programmatic relevance and potential time tables for funding (see below, Section VII. Agency Contacts). The limited scope and shorter duration of the SHINE II R01 are not optimal for Early Stage Investigators (ESIs) and New Investigators (NIs), who should contact Scientific/Research staff prior to submission of an application to this FOA.

With this solicitation, the SMART Office seeks applicants to design and implement a program that aims to safeguard amateur athletes through the prevention of sexual, physical and emotional abuse in the athletic programs of the USOPC and each NGB. Under the KYAS program, the grantee will design and implement measures to protect young athletes through the development of educational materials, training programs and policies, and necessary tools to help prevent and address identified abuse. Additionally, the grantee will develop background screening policies for new and existing USOPC organizational staff, including coaches, instructors and volunteers, and oversee regular and random audits to ensure that, once implemented, the policies and procedures to prevent and identify amateur athlete abuse are followed correctly. The KYAS program requires reporting of any allegations of sexual and physical abuse, following applicable state and federal reporting requirements.

This funding opportunity provides financial support to non-profits, local and tribal governments, and businesses for projects that promote renewable wood energy and innovative wood products, particularly in underserved communities and areas with high unemployment.

This funding opportunity provides financial support to non-profit organizations and educational institutions working to strengthen law enforcement and justice systems in Kenya and Tanzania to combat wildlife trafficking and protect endangered species.