Grants for Public and State controlled institutions of higher education - Federal

Executive Summary: The U.S. Embassy Ashgabat, Turkmenistan announces an open competition to implement American Spaces Programs project at the four American Spaces in Turkmenistan located in Ashgabat, Dashoguz, Mary and Turkmenabat. The program will include a variety of programs in a) enhancing English skills (e.g., drama club, English club and sessions, etc.), b) introducing to STEM skills (e.g., math contest, NASA apps development challenge, coding, etc.), c) business skills development (e.g., interactive economics, business camp, etc.), and d) climate change awareness. The primary audience for these programs will be Turkmen youth ages 10 to 25, including girls and women, school and university students and young professionals, especially from economically disadvantaged backgrounds. The program will also engage alumni from previous Embassy programs as experts and program coordinators as well as bring local businesses and nonprofit organizations to share their expertise and build stronger local professional communities. Potential implementer will be responsible for planning, executing, closing, and monitoring and evaluation of the programs. The expected date range for implementation of this project is October 1, 2024 through September 30, 2025. Potential candidates can apply to administer all of the suggested programs below or just one or several of the programs at a time. Background: American Spaces are the premier public diplomacy platform of the U.S. Embassy Ashgabat in Turkmenistan that further strengthens mutual understanding and friendship between the people of Turkmenistan and the United States of America. American Spaces are located in Ashgabat, Dashoguz, Mary and Turkmenabat and offer English resources and development opportunities to meet interests of diverse audiences, while also serving as gateways for the Turkmen citizens to learn about American society, culture and education. The American Spaces are well known in the community for their regular English-language activities, such as conversation groups with native speakers, workshops with visiting specialists, and regular presentations by Americans on U.S. life and culture. American Spaces also partner with international and local organizations to conduct highly impactful programs, such as Academy for Women Entrepreneurship in partnership with Arizona State University, a variety of STEM programs to introduce local youth to web design and app development, as well as book festivals and eco festivals. The American Spaces Program aims to support implementing a range of diverse programming activities with key primary audiences in all four American Spaces across Turkmenistan. Project Goal: Increase mutual understanding between the United States and Turkmenistan through experiential learning activities that promote English language, innovation, entrepreneurship, environmental protection, and gender equality in STEM. Primary Audiences: The primary audiences for the American Spaces Program in Turkmenistan are: a. School and university students b. School and university teachers c. Young professionals, such as current/aspiring entrepreneurs, especially from economically disadvantaged backgrounds d. Girls and women e. Civil society representatives f. USG programs alumni Project Objectives: Objective 1: Enhance STEM and problem-solving skills of at least 500 youth, in Ashgabat and in the regions. Objective 2: Create a network of youth interested in tech and STEM by facilitating community networking opportunities between Turkmen youth and tech communities in Turkmenistan and the United States. American Spaces Program may include the following suggested STEM programs at American Spaces in Turkmenistan: Tech Lab will cover two primary audiences and can cover program coordinator and trainers fee, activities, supplies, catering and promotional materials in all four American Spaces: o A. Coding skills lab will introduce around 100 English speaking school graduates and young professionals, ages 18 30, to the basics of web design and digital skills through a 4-month long program. This program aims to help local youth pursue education in computer science and enter tech careers in Turkmenistan. o B. Technovation Girls will provide program support to around 150 schoolgirls, ages 8-18, in app development and tech entrepreneurship to enable them to successfully compete in the global tech entrepreneurship competition. Regional Math Contest. American Spaces in Turkmenistan plan to organize a first-ever math tournament for school students, ages 10-14, based on the popular U.S. math competition 24 Challenge. The budget may include study materials for a series of 3-month long sessions, tournament materials for the final national tournament in Ashgabat and travel expenses of winners from regional tournaments in each American Corner from Dashoguz, Mary and Turkmenabat. The NASA International Space Apps Challenge. This program aims to engage English speaking students ages 16 - 25 to participate in the global NASA Space Apps challenge through a series of in-person workshops and events in the American Spaces. The budget may include project coordinator and trainer fees, training/activities supplies, final Hackathon promo materials, catering, and social media content creation to amplify the program. Objective 3: Increase English language skills among at least 500 local youth by providing hands-on English learning activities, including but not limited to: An English Immersion program to engage up to 500 English speakers throughout the year, ages 10 to 18 to enhance their English skills through topics on U.S. values of diversity and inclusion, climate change, media literacy, entrepreneurship, and public speaking, through a variety of activities and projects. The budget can include trainer fees, training supplies, promotional items and coffee breaks. This project may include: a. English Drama Club that might organize a play by an American author, that can be also performed at local events and schools through a mobile mini-theater. b. English language learning immersive camps that can be conducted during spring, summer and fall school breaks. c. English language book clubs that can introduce the American Corner resources and services (e.g., English resource books, readers, magazines and games) to improve English skills. Objective 4: Increase knowledge and awareness of climate change mitigation efforts among 100 young eco-champions through educational and networking programs focused on climate action, innovative business best practices and entrepreneurial strategies. These programs may include the following: Climate Champions organize a 10-day climate change awareness program for English speaking students in all American Spaces (ages 16 - 25) throughout September 2024 to August 2025 that will include workshops, field trips, and community service activities conducted in partnership with the local eco activists and nonprofits. During the program participants will learn about the challenges posed by climate change, water, energy, sustainable consumption, and discuss common myths and explore best practices from the United States. The budget may include project coordinator and trainers fees, training supplies, promotional materials, and coffee breaks in American Spaces. Farmcraft program. American Spaces in Turkmenistan plan to organize a global North America Scholastic Esports Federation (NASEF) Farmcraft competition for school students, ages 10-18. This educational program uses the popular game Minecraft to introduce the basics of agricultural science, food security and climate change. The budget may include facilitator fees for a series of 3-month long sessions, training supplies, promotional materials, and coffee breaks in American Spaces. Objective 5: Increase interest in business and entrepreneurship among at least 100 local youth in Turkmenistan through training on business development and economics. These programs may include the following: Business Skills program. The program can run for middle and high school students for 40 hours, with the final pitch events at American Spaces that will bring together local and international business communities. Playful Economics. Based on the playful economics curriculum, this program will introduce the basics of economics concepts in a fun way to middle and high school students (ages 12-18). American Spaces plan to organize a series of programs and activities throughout the year for local youth ages 12-18 across all American Spaces. The budget may include project coordinator and trainer fee, training supplies, and promotional materials. The goal of the program is to introduce the basics of business, entrepreneurship, and other economic concepts. All the programs proposed by the potential implementer should have clear goals and objectives, clear output and outcome statements. Proposals should also indicate plans for reports about success and impact of the programs, social media presence, photo release procedures and other logistics. Potential implementer will be responsible for planning, executing, closing, and monitoring and evaluation of the program.

This funding opportunity provides financial support for small-scale public diplomacy projects that strengthen the relationship between the United States and Gabon, targeting nonprofit organizations, educational institutions, and individuals focused on entrepreneurship, English language development, and cultural preservation.

This funding opportunity provides financial support for the development of innovative informatics tools that will help researchers effectively utilize the human pangenome reference to advance genomics research across various applications.

This funding opportunity supports U.S. institutions and non-profits in organizing conferences and workshops that advance research, education, and community engagement in the mathematical sciences, with a focus on inclusivity and diversity.

This funding opportunity provides financial support for projects that remove barriers to fish migration, benefiting local communities and ecosystems, particularly in underserved areas.

This funding opportunity provides financial support to various organizations for developing and implementing public health strategies aimed at improving brain health and addressing the challenges of Alzheimer’s disease and related dementias, particularly for underserved populations.

To advance the field of patient-centered clinical decision support through research that tests tools and resources in real-world settings. The mission of the Agency for Healthcare Research and Quality (AHRQ) is to produce evidence to make healthcare safer, higher quality, and more accessible, equitable, and affordable, and to work within the U.S. Department of Health and Human Services and with other partners to make sure the evidence is understood and used. The purpose of this Notice of Funding Opportunity (NOFO) is to conduct research on patient-centered clinical decision support (PC CDS), a nascent area within the larger field of CDS. Through the AHRQ-funded Patient Centered Outcomes Research (PCOR) CDS Initiative and the CDS Innovation Collaborative specifically, PC CDS resources are now publicly available for interested researchers to further build upon, develop, and test, in real-world settings. Innovative research is needed to understand how to make traditional, clinician-facing CDS more patient-centered, while also engaging patients, families, and caregivers in a co-design process to design and implement these tools. BACKGROUND Clinical decision support refers to digital tools that are used to help inform patient care. Patient-centered clinical decision support (PC CDS), in contrast to traditional clinician-facing CDS, is CDS that focuses on the patient, or their caregiver, and facilitates their active involvement in healthcare decision-making with their clinicians. PC CDS uses information from patient-centered outcomes research findings and/or patient-specific information and has the potential to be transformative by enabling higher-quality care delivery and improved outcomes. PC CDS can also support shared decision making (SDM), which AHRQ defines as a collaborative process in which patients and clinicians work together to make healthcare decisions informed by evidence, the care team's knowledge and experience, and the patient's values, goals, preferences, and circumstances. PC CDS can also support shared care planning enabling patients, caregivers, and clinicians to work together to tailor a clinical plan to align with a given patients priorities and goals. PC CDS is a developing field and has the potential to increase the quality and experience of patient care. AHRQ’s CDS Initiative is supported by the Patient Centered Outcomes Research Trust Fund (PCOR TF) and is guided by AHRQ’s PCOR TF strategic framework (https://www.ahrq.gov/pcor/strategic-framework/index.html). Since 2016, AHRQ’s PCOR CDS Initiative has been building tools, concepts, frameworks, and conducting pilot projects. Much of AHRQ’s recent effort has focused on patient-centered CDS, and several past projects have generated resources that could be highly useful to the developing PC CDS field. Examples of these projects include AHRQ’s PC CDS Learning Network and CDS Connect, as well as a project that assessed the current state and future directions with PC CDS. Additional information for CDS projects is available on the PCOR CDS Initiative webpage. AHRQ’s most recent PC CDS project, the CDS Innovation Collaborative, or CDSiC, is a multi-component stakeholder-driven initiative that produced a rich set of resources and tested concepts around different aspects of PC CDS. As part of the CDSiC, four workgroups were formed, each around a specific area of PC CDS, with the charge to create products (e.g., frameworks, guides, checklists) that could be used in the clinical field to establish or measure use of PC CDS. These products could address clinical workflows or the development of CDS technologies, among other areas related to PC CDS. During the first two years of the CDSiC, these workgroups created numerous products that addressed PC CDS in different areas. These areas included CDS outcomes, trust and patient-centeredness, and scaling and dissemination. One workgroup also focused on the existing standards and regulatory frameworks that could impact the future uptake and use of PC CDS. Applicants can examine, using these products and tools, how PC CDS can support shared decision making and care planning among individuals with complex needs including older adults, people living with multiple chronic conditions, frailty, disabilities, and/or socioeconomic disadvantage and how this may foster the delivery of person-centered care. They may also study strategies to scale and spread effective tools including use in lower resourced and safety net instituions. Applicants responding to this NOFO must propose to use the resources developed by AHRQ's PCOR CDS Initiative, or any of the many products developed by the ongoing CDSiC, to further explore their usefulness, impact, and practical application in real-world settings. For example, CDSiC products that could be used may include the Taxonomy of Patient Preferences, Integration of Patient-Centered CDS into Shared Decision Making, Approaches to Measuring Patient-Centered CDS Workflow and Lifeflow Impacts, or the PC CDS Performance Measurement Inventory User Guide. Links to and descriptions of the products are available on the CDSiC Stakeholder Center webpage (https://cdsic.ahrq.gov/cdsic/cdsic-stakeholder-community-outreach-center ) The CDSiC's Innovation Center (https://cdsic.ahrq.gov/cdsic/innovation-center) developed a comprehensive report around measurement of PC CDS and created two pilot dashboards that can help clinicians understand and use Patient Generated Health Data. Additional information on other PCOR CDS projects is available at https://cds.ahrq.gov/about. Examples of Highly Responsive Projects include: A community hospital with a large priority population, selects from the CDSiC portfolio of projects generated by the Trust and Patient-Centeredness workgroup. The recipient selects the source credibility product from the Trust and Patient Centeredness workgroup and conducts a study to understand how their population perceives the information they receive from within their existing electronic health record (EHR) system. Patients provide input, and the approach is assessed against existing CDS tools, as well as the definition of PC CDS as defined by the CDSiC, to assess their level of patient-centeredness. A small startup company is developing applications (apps) to help patients improve their healthcare. The startup leverages two products from the CDSiC standards and regulatory frameworks workgroup: Advancing Standardized Representations for Patient Preferences to Support Patient-Centered Clinical Decision Support and an Environmental Scan that reveals opportunities to evolve standards and regulatory frameworks to advance PC CDS. The company works with a patient advocacy organization to co-design the patient-facing PC CDS app, uses standards to leverage existing patient generated health data (PGHD), and incorporates a final assessment as to the level of patient-centeredness of their technology. A primary care physician group is working to reduce clinician burnout with the goal of improving patient outcomes. The group looks at the CDSiC’s Taxonomy of Patient Preferences and assesses how they can incorporate these concepts into restructured workflows. The group then also uses CDSiC’s product called Approaches to Patient-Centered CDS Workflow and Lifeflow Impact, which provides a framework to help identify the optimal point for a patient-centered CDS tool’s deployment in a patient’s lifeflow. Their study will also assess how increased patient-centeredness in their CDS tools do not inadvertently have a negative impact on clinician workflows or experience. All projects are encouraged to: Incorporate Clinical Quality Language (CQL) and other HL7 standards into their project design, if appropriate for developing, integrating, (or modifying) their CDS with their EHR system or other health information technology (Health IT) components to become more patient-centered. OBJECTIVES AND SCOPE This NOFO aims to support innovative collaborative research to understand how clinical decision support tools in real-world settings can be improved to become more patient centered. Recipients will become part of an existing community of researchers who have an interest in PC CDS including AHRQ, the CDSiC, and other researchers. Interested applicants may include health information technology experts, patient advocates and representatives, clinicians, electronic health record developers, policymakers, payors, as well as leaders from research and academic medical institutions. All projects must: Utilize one or more of the products from the CDSiC or the PCOR CDS Initiative, which are available on the project website: cdsic.ahrq.gov, or another resource available from the PCOR CDS Initiative (cds.ahrq.gov), which includes the PC CDS Learning Network, CDS Connect, or AHRQ's Evaluation project that assessed the current state and future directions with PC CDS; If CDSiC products are used specifically, applicants must identify if any other frameworks are being used to evaluate the performance of their PC CDS (e.g., RE-AIM or other); Apply the definition of patient-centered CDS (available here: https://cdsic.ahrq.gov/cdsic/patient-centered-clinical-cds-infographic) and describe the degree to which each of the 4 elements are incorporated into the patient-centered CDS tool: knowledge, patient data, delivery, and use. Apply an equity lens, consistent with AHRQ's PCOR Strategic Framework. Apply at least 1 of the 4 priorities from AHRQ's PCOR Strategic Framework. Include meaningful and substantial participation from patients and/or patient representatives in the co-design, implementation, and evaluation of their research, to also be reflected in the proposed budget. Fully describe their research ecosystem. If developing or extending a digital tool, be mobile friendly to be more accessible to a broader population (for example, a patient-facing portal, website, etc.). If the research or tool will be incorporated into an EHR system, the facility must have a mature, functioning EHR system (e.g., the facility is not planning any significant system upgrade or migration). Otherwise, an alternative means to test and evaluate the selected CDS product can be described. If the research strategy intends to modify an existing clinical workflow that is currently clinician-focused, to become a patient-centric or patient-facing approach, then the strategy must include an evaluation component to characterize the performance of the PC CDS tool versus the previous clinician-facing workflow. If the proposed project plans to promote implementation of SDM, it should align with AHRQ’s definition of SDM (available here: https://www.ahrq.gov/sdm/about/index.html) and include at least one validated measure of SDM in its evaluation.

This funding opportunity provides financial support for the development of high-capacity electric vehicle charging infrastructure aimed at medium- and heavy-duty vehicles, targeting U.S.-based educational institutions, businesses, governments, and tribes to enhance sustainable transportation along key freight routes.

The DoD Kidney Cancer, Idea Development Award is a funding opportunity aimed at supporting innovative, high-impact kidney cancer research projects, with a focus on scientific rationale, preliminary data, innovation, and potential impact, and encourages collaborations among academia, industry, military services, and other federal agencies, with a budget not exceeding $800,000 for individual projects and $1.2M for partnered projects.

The Office of English Language Programs (ECA/A/L) of the Bureau of Educational and Cultural Affairs announces an open competition for the FY 2024 Online Professional English Network (OPEN) Program, which offers foreign English teaching professionals and language learners the opportunity for professional development through high-quality, accessible, and openly licensed virtual resources, including online English language teacher development courses, online English language learning courses, virtual exchanges, webinars, an alumni community of practice (CoP), multiple social media channels, and other types of engaging and innovative online learning. In cooperation with ECA/A/L, the award recipient will manage the selection, development, and delivery of appropriate online TESOL (Teaching English to Speakers of Other Languages) learning courses which will be offered to English language educators or learners on an easily accessible online learning management system (LMS). Courses, webinars, and other virtual programming may be offered globally, regionally, or to specific countries at the request of U.S. embassies. Courses and exchanges are developed by U.S. academic institutions, educational NGOs, or TESOL professional associations, while webinars and other social media programming are developed by U.S.-based TESOL professionals. All content produced for this program should be accessible according to Section 508 compliance standards, openly licensed with a Creative Commons Attribution (CC BY) License, and follow best practices for diversity, equity, inclusion, and accessibility (DEIA). Please see the full announcement for additional information.

A. PROGRAM DESCRIPTION U.S. Embassy Maseru announces an open competition for organizations and individuals interested in submitting applications to implement a project that will deliver tailored human rights training modules for Lesotho Correctional Services (LCS) leadership and policymakers, covering topics such as international human rights standards, inmate rights, ethical conduct, and conflict resolution. This training should include interactive workshops and scenario-based learning exercises. Additionally, the project will support the establishment of a dedicated human rights unit within LCS to oversee compliance and investigate reported abuses.Program Objectives:1. Conduct comprehensive human rights training for Lesotho law enforcement agencies, and specifically LCS, building on previous UNDP training, to enhance their understanding and application of human rights principles in daily operations.2. Support the creation of a dedicated human rights unit within LCS. Establish criteria the new unit can use to monitor and report human rights violations, oversee compliance with human rights standards and investigate reported abuses effectively to ensure accountability and transparency.Anticipated Outcome(s):1. Increased awareness, knowledge, and understanding of international human rights principles and ethical conduct among LCS officials will allowfor an environment where preventative measures can be implemented to forestall human rights violations.2. Improved ability to handle conflict resolution and protect inmate rights.3. Improved reporting and accountability mechanisms for addressing human rights violations within LCS.4. Improved oversight of human rights compliance within the LCS.5. Reduced incidents of human rights abuses and enhanced respect for inmate rights within correctional facilities.Participants and Audiences: All applicants must be registered Civil Society Organizations, Non-Governmental Organizations, or individuals with demonstrated experience in human rights training and capacity-building.Any application that is received after the deadline, is incomplete, or is missing required documentation will be rejected.Please Note: The U.S Embassy Maseru retains the right to ask for additional documents not included in this NOFO.Application guidelines can be requested via email, [email protected] U.S. Embassy Maseru will accept applications from July 16, 2024 to August 16, 2024

The FY24 PCRP Data Science Award mechanism supports research where quantitative and analytical approaches, processes, and/or systems are developed and/or used to obtain knowledge and insight from large and/or complex sets of prostate cancer data. If successful, the studies will enable progress toward addressing one or more of the FY24 PCRP Overarching Challenges. It is expected that any resources, tools, or computational processes generated by this award will be openly shared with the prostate cancer research and patient community. This mechanism is intended to fund research built upon the logic, concepts, and methods of one or more of the following research areas as they pertain to prostate cancer: Computational biology Bioinformatics Artificial intelligence and machine learning Epidemiology Analysis of omics data Medical imaging Digital pathology Analysis of other clinically annotated datasetsApplications may combine diverse data types for integrative analysis to increase knowledge about prostate cancer with respect to the FY24 PCRP Overarching Challenges. Applications that propose to develop resources or tools that allow research, clinical care, and patient community access to standardized and harmonized datasets for real-time clinical care applications are of particular interest; however, this award must not be used to support the development of new datasets. Studies utilizing data derived from large patient studies that include long-term health records or repositories with well-annotated and high-quality biospecimens are encouraged.Key Features: Research Approach: Applications may propose development of a new data-science-driven tool or apply an existing tool or method to gather and analyze information from large datasets with the intent of advancing prostate cancer research and patient care relative to the FY24 PCRP Overarching Challenges. Inclusion of preliminary data to support the scientific rationale and feasibility of research approaches is strongly encouraged, but not required. Any preliminary data provided should be from the laboratory of the Principal Investigator(s) (PI[s]) or member(s) of the collaborating team. Applicants are encouraged to include plans for rigorous validation, benchmarking, comparisons, and/or evaluations to assess the quality or utility of the tools and/or approaches that will be used or developed under this award. Any datasets used in the study design must be from established, retrospective databases and be sufficient in size to provide appropriate analytical and statistical power. Prospective recruitment of human subjects and/or clinical trials is not allowed under this funding opportunity. Applicants are expected to provide documentation demonstrating access to the appropriate datasets and/or patient samples in numbers sufficient to achieve robust results. Impact: Applications are required to clearly communicate how the proposed quantitative and/or analytical approaches, processes, and/or systems will address and provide a solution to one or more of the FY24 PCRP Overarching Challenges. The potential impact of the research, both short- and long-term, should be clearly described, including how the anticipated outcomes or products are distinct from existing research efforts in this area and/or how they will significantly outperform current approaches in this area. High-impact research will, if successful, significantly advance prostate cancer research and/or patient care. Data and Resource Sharing Plan: It is expected that any resources, tools, and computational processes that are developed under this award will be openly shared with the prostate cancer research and patient community. Plans must be provided for how additional data generated by future studies will be incorporated to further inform and refine the data science tools, processes, and/or methods generated and/or used in this study. Refer to the CDMRPs Policy on Data Resource Sharing located on the Electronic Biomedical Research Application Portal (eBRAP) Funding Opportunities Forms web page https://ebrap.org/eBRAP/public/Program.htm for more information about the CDMRPs expectations for making data and research resources publicly available.Partnering PI Option: The FY24 PCRP Data Science Award encourages applications that include meaningful and productive collaborations between investigators. The PIs may have expertise in similar or disparate scientific disciplines, but each PI is expected to bring distinct contributions to the application; collaborations between data scientists and clinicians are highly encouraged. The Partnering PI Option is structured to accommodate two PIs. One PI will be identified as the Initiating PI and will be responsible for the majority of the administrative tasks associated with application submission. The other PI will be identified as a Partnering PI. Both PIs should contribute significantly to the development and execution of the proposed research project, including the Project Narrative, Statement of Work (SOW) and other required components. If recommended for funding, each PI will be named on separate awards to the recipient organization. Each award will be subject to separate reporting, regulatory, and administrative requirements. For individual submission requirements for the Initiating and Partnering PI, refer to Section II.D.2, Content and Form of the Application Submission.A congressionally mandated Metastatic Cancer Task Force was formed with the purpose of identifying ways to help accelerate clinical and translational research aimed at extending the lives of advanced state and recurrent patients. As a member of the Metastatic Cancer Task Force, the CDMRP encourages applicants to review the recommendations (https://health.mil/Reference-Center/Congressional-Testimonies/2018/05/03/Metastatic-Cancer-Research) and submit research ideas to address these recommendations provided they are within the limitations of this funding opportunity and fit within the FY24 PCRP priorities.Innovative research involving nuclear medicine and related techniques to support early diagnosis, more-effective treatment, and improved health outcomes of active-duty Service Members and their Families is encouraged. Such research could improve diagnostic and targeted treatment capabilities through noninvasive techniques and may drive the development of precision imaging and advanced targeted therapies.Applications from investigators within the military services and applications involving multidisciplinary collaborations among academia, industry, the military services, the U.S. Department of Veterans Affairs (VA), and other federal government agencies are highly encouraged. These relationships can leverage knowledge, infrastructure, and access to unique clinical populations that the collaborators bring to the research effort, ultimately advancing research that is of significance to Service Members, Veterans, and/or their Families. If the proposed research relies on access to unique resources or databases, the application must describe the access at the time of submission and include a plan for maintaining access as needed throughout the proposed research.All projects should adhere to a core set of standards for rigorous study design and reporting to maximize the reproducibility and translational potential of clinical and preclinical research. The standards are described in SC Landis et al., 2012, A call for transparent reporting to optimize the predictive value of preclinical research, Nature 490:187-191 (http://www.nature.com/ nature/journal/v490/n7419/full/nature11556.html). While these standards are written for preclinical studies, the basic principles of randomization, blinding, sample-size estimation, and data handling derive from well-established best practices in clinical studies.Clinical trials are not allowed. A clinical trial is defined in the Code of Federal Regulations, Title 45, Part 46.102 (45 CFR 46.102) as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include a placebo or another control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes.Studies that do not seek to measure safety, effectiveness, and/or efficacy outcome(s) of an intervention are not considered clinical trials.For the purposes of this funding opportunity, research that meets the definition of a clinical trial is distinct from clinical research. Clinical research encompasses research with human data, human specimens, and/or interaction with human subjects. Clinical research is observational in nature and includes:(1) Research conducted with human subjects and/or material of human origin such as data, specimens, and cognitive phenomena for which an investigator (or co-investigator) does not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention. Research meeting this definition may include but is not limited to: (a) mechanisms of human disease, (b) diagnostic or detection studies (e.g., biomarker or imaging), (c) health disparity studies, and (d) development of new technologies.(2) Epidemiologic and behavioral studies that do not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention.(3) Outcomes research and health services research that do not fit under the definition of clinical trial.Excluded from the definition of clinical research are in vitro studies that utilize human data or specimens that cannot be linked to a living individual and meet the requirements for exemption under 46.104(d)(4) of the Common Rule.The funding instrument for awards made under the program announcement will be grants (31 USC 6304).The anticipated direct costs budgeted for the entire period of performance for an FY24 PCRP Data Science Award should not exceed $1.0M. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.Awards supported with FY24 funds will be made no later than September 30, 2025.The CDMRP expects to allot approximately $11.2M to fund approximately seven Data Science Award applications. Funding of applications received is contingent upon the availability of federal funds for this program, the number of applications received, the quality and merit of the applications as evaluated by peer and programmatic review, and the requirements of the government. Funds to be obligated on any award resulting from this funding opportunity will be available for use for a limited time period based on the fiscal year of the funds. It is anticipated that awards made from this FY24 funding opportunity will be funded with FY24 funds, which will expire for use on September 30, 2030.

The IIJA/IRA Bureau of Land Management National Operations Center (NOC) Wildlife Resource Management grant aims to fund projects by state, local, and tribal governments, nonprofits, and higher education institutions that focus on wildlife habitat restoration, connectivity, and climate resilience on public lands, with a total of $800,000 available for individual awards ranging from $25,000 to $500,000, and applications due by September 30, 2024.

This funding opportunity provides financial support to state and local governments, tribal governments, educational institutions, and non-profit organizations to enhance commercial motor vehicle safety and reduce crashes through various innovative projects.

This grant provides funding to support postdoctoral researchers transitioning to independent faculty positions, focusing on innovative research in pain management and substance use disorders.

This funding opportunity supports the development of innovative molecular and genetic tools for neuroscientific research, enabling precise access to specific brain cell types across various vertebrate species, with a strong emphasis on collaboration, inclusivity, and resource sharing.

This funding opportunity seeks to partner with a variety of organizations to enhance justice, protect human rights, and promote security initiatives globally.

This funding opportunity provides financial support to organizations that mentor at-risk youth, helping them reduce delinquency and improve their life outcomes through training, resources, and technical assistance.

The Agency will make grants to public bodies and private nonprofit corporations, (such as States, counties, cities, townships, and incorporated towns and villages, boroughs, authorities, districts, and Indian tribes on Federal and State reservations) to provide associations Technical Assistance and/or training with respect to essential community facilities programs. The Technical Assistance and/or training will assist communities, Indian Tribes, and Nonprofit Corporations to identify and plan for community facility needs that exist in their area. Once those needs have been identified, the Grantee can assist in identifying public and private resources to finance those identified community facility needs.

The "IIJA/IRA Bureau of Land Management National Operations Center (NOC) Threatened and Endangered Species Program" grant offers funding between $25,000 and $500,000 to government agencies, educational institutions, and nonprofits for projects aimed at conserving, recovering, and reducing threats to federally listed and BLM sensitive species on public lands, with a total of $800,000 available and a deadline of September 30, 2024.