Grants for Public housing authorities - Federal

This funding opportunity is designed to strengthen clinical and translational research capabilities in health organizations located in underserved states, enabling them to address local healthcare challenges through enhanced infrastructure, workforce development, and community engagement.

This funding opportunity provides financial support for organizations to develop and validate digital therapeutic technologies designed to treat substance use disorders, with the goal of achieving FDA authorization.

The Unaccompanied Children Lived Experience and Youth Engagement Support Program is forecasted to provide funding to establish, manage, and evaluate a Lived Experience Community Council and Lived Experience Leadership Academy comprised of former unaccompanied children and individuals who sponsored children from ORR care. The recipient shall recruit, identify, orient, and train lived experience experts that reflect the demographic diversity (e.g., age, language, etc.) and varied experiences and circumstances (e.g., pregnant/parenting youth, survivors of human trafficking, etc.) of former unaccompanied children and sponsors. Therefore, prior experience developing programming centering lived experience and youth voice and/or supporting unaccompanied children, sponsors, and reunified families is highly desirable. These lived experience bodies have two objectives. The first is to collect feedback from former unaccompanied children and reunified families about their first-hand experience integrating to the United States. The second is to positively impact the lives of Community Council and Leadership Academy members by building their capacity to serve as leaders within their respective communities. The recipient shall provide the necessary resources, such as personnel, to support the implementation of the lived experience bodies. Task areas will include: a) development of the Community Council implementation plan and Leadership Academy curriculum; b) development of a web-based application; c) selection of eligible candidates to the appropriate lived experience body; d) project management; e) interpretation and translation services for, and during, community meetings; f) secure technology for members to participate in virtual meetings; g) compensate members for their time; h) as separate cohorts, coordinate and implement Washington Weeks for the Community Council and Leadership Academy to meet with government leaders and relevant stakeholders, and i) disseminate to the ORR-funded network feedback obtained through the lived experience bodies' work that centers youth voice and lived experience.

The purpose of the NIH Pathway to Independence Award (K99/R00) program is to increase and maintain a strong cohort of new and talented, NIH-supported, independent investigators. This program is designed to facilitate a timely transition of outstanding postdoctoral researchers with a research and/or clinical doctorate degree from mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions. The program will provide independent NIH research support during this transition in order to help awardees to launch competitive, independent research careers.

The purpose of this Notice of Funding Opportunity (NOFO) is to stimulate translational efforts in developing and implementing accessibility devices or interventions that apply new technologies to address challenges faced by individuals living with visual impairment. Critical elements of applications include a clear set of milestones that support development and testing of the tool, device, or intervention proposed; multidisciplinary and collaborative teams that include individuals with lived experience; and a tractable dissemination plan. The overall goal of the program is to push the boundaries of innovation in technology development to address accessibility needs of individuals with visual impairment and create resources that will be made available to the community. This NOFO uses a milestone driven and phased mechanism of award. Initial technology development and feasibility activities (R61 phase) may transition to expanded research support (R33 phase) for validation, larger-scale feasibility, and effectiveness studies. All applications must address both R61 and R33 phases.

The Rural eConnectivity Program (ReConnect) Program provides loans, grants, and loan/grant combinations to facilitate broadband deployment in rural areas. In facilitating the expansion of broadband services and infrastructure, the program will fuel long-term economic development and opportunities in rural America. The ReConnect Program is authorized by the Consolidated Appropriations Act, 2018 (Pub. L. 115-141), which directs the program to be conducted under the Rural Electrification Act of 1936 (7 U.S.C. 901 et seq ). The policies and procedures for the ReConnect Program are codified in a final rule, 7 CFR part 1740, that was published in the Federal Register on February 26, 2021 (86 FR 11603). The Rural Utilities Service (RUS), a Rural Development agency of the United States Department of Agriculture (USDA), is issuing a Notice of Funding Opportunity (NOFO) to announce that it is accepting applications for the ReConnect Program. In addition, the NOFO defines requirements that are determined at the time a funding announcement is published, as outlined in the regulation. Beginning on March 22, 2024, applications can be submitted through the RUS on-line application portal until 11:59 a.m. Eastern on May 21, 2024. Applications will not be accepted after May 21, 2024 until a new application opportunity has been opened with the publication of an additional NOFO in the Federal Register . The Agency encourages applicants to consider projects that will advance the following key priorities: Assisting rural communities recover economically through more and better market opportunities and through improved infrastructure. Ensuring all rural residents have equitable access to Rural Development programs and benefits from Rural Development funded projects. Reducing climate pollution and increasing resilience to the impacts of climate change through economic support to rural communities. All applicants should carefully review and prepare their applications according to instructions in the ReConnect Program Application Guide and program resources. This Program Guide and program resources can be found at https://www.usda.gov/reconnect/forms-and-resources. Applications must be submitted through the RUS on-line application system available on the program web site at https://www.usda.gov/reconnect/. Please submit any ReConnect questions or comments using our Contact Us Form.

This funding opportunity supports innovative research teams in developing and implementing advanced artificial intelligence models to improve HIV diagnosis, prevention, and treatment, while ensuring ethical practices and community engagement.

This Notice of Funding Opportunity (NOFO) invites new applications for Centers for Collaborative Research in Fragile X andFMR1-Associated Conditions (hereafter termed "Fragile X Centers"). Despite many remarkable advances in fundamental knowledge about FMR1-associated conditions, gaps in knowledge remain about the processes that drive the variability in clinical features (phenotypic heterogeneity) among affected individuals. In this round of competition, therefore, all centers will be required to identify an overarching theme directed at broadening our understanding of factors underlying the phenotypic heterogeneity and/or variability in response to interventions seen in one or more FMR1 associated conditions. Successful Fragile X Centers will be composed of multidisciplinary teams of basic, translational, clinical, and/or data science investigators applying precision medicine approaches (seeking to understand which mechanisms and interventions are most applicable to specific individuals or groups) to address the center's proposed overarching theme. This NOFO includes specific requirements about inclusion of research on human subjects or human phenotypic data; diversity of participants or materials being studied; the types of allowable clinical trials; and involvement of early-stage investigators. Applications that do not adhere to these requirements will be considered nonresponsive to this NOFO and will be withdrawn. In addition, this NOFO requires a Plan for Enhancing Diverse Perspectives (PEDP), which will be assessed as part of the scientific and technical peer review evaluation. Applications that fail to include a PEDP will be considered incomplete and will be withdrawn.Applicants are strongly encouraged to read the NOFO instructions carefully and view the availablePEDP guidance material.

The purpose of the Title V Competitive Sexual Risk Avoidance Education (SRAE): New Mexico funding opportunity is to fund projects in New Mexico to implement sexual risk avoidance education that teaches participants how to voluntarily refrain from non-marital sexual activity. Successful applicants are expected to submit plans for the implementation of sexual risk avoidance education that normalizes the optimal health behavior of avoiding non-marital sexual activity, with a focus on the future health, psychological well-being, and economic success of youth. Applicants must agree to: 1) use medically accurate information referenced to peer-reviewed publications by educational, scientific, governmental, or health organizations; implement an evidence-based approach integrating research findings with practical implementation that aligns with the needs and desired outcomes for the intended audience; and 2) teach the benefits associated with self-regulation, success sequencing for poverty prevention, healthy relationships, goal setting, and resisting sexual coercion, dating violence, and other youth risk behaviors such as underage drinking or illicit drug use without normalizing teen sexual activity. The Title V SRAE legislation requires unambiguous and primary emphasis and context for each of the A-F topics to be addressed in program implementation. Additionally, there is a requirement that messages to youth normalize the optimal health behavior of avoiding non-marital sexual activity.

Funding Opportunity Description The NIH Research Education Program (R25) supports research educational activities that complement other formal training programs in the mission areas of the NIH Institutes and Centers. The overarching goal of this R25 program is to support educational activities that encourage individuals from diverse backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences, to pursue further studies or careers in research. Background A major goal of the National Plan to address Alzheimer’s Disease (AD) and Alzheimer’s Disease-related Dementias (ADRD) is to reduce the burden of AD/ADRD by accelerating research toward treatments, improving care and support for people facing these conditions now, and reducing the risk of AD/ADRD by promoting brain health. Despite this, there is a shortage of scientists conducting the wide variety of necessary innovative and interdisciplinary research projects, including basic biomedical, clinical, translational, prevention, and treatment research on AD/ADRD. This Funding Opportunity Announcement (FOA) aims to address goal G-4 of the National Institute on Aging's Strategic Directions for Research (2020-2025): Attract and train more researchers from diverse scientific and cultural backgrounds." This will include supporting the recruitment of early-stage investigators from diverse backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences, to the NIH AD/ADRD portfolio. This FOA also aims to address the lack of early exposure to high-quality, hands-on research education experiences in the AD/ADRD field, another major barrier to increasing the AD/ADRD capable workforce. To further expand the AD/ADRD training pipeline for earlier stage students, NIA will support summer research experiences for high school students, undergraduates, or science teachers. The expectation is that such a program would incubate and develop the next generation of early-stage investigators to pursue research careers representative of in NIA mission critical areas, namely AD/ADRD research. Proposed programs should provide authentic "open-ended", hands-on exposure to AD/ADRD research as it relates to aging as part of a comprehensive program based in sound educational practices designed to stimulate the interest and advance the knowledge base of participants. In addition to hands-on research experiences, programs are expected to include complementary educational enrichment activities that support the participants' scientific development, such as relevant workshops (e.g., scientific writing and presentation skills), journal clubs, technical laboratory coursework, and training in rigor and reproducibility. Program goals and objectives should be grounded in literature and appropriate for the educational level of the audience to be reached, including the content to be conveyed, and the intended outcome(s). Outcomes for high school students may include preparing them for undergraduate admissions and enhancing their interest in pursuing a science decree. Outcomes for college students may include: reinforcing their intent to graduate with a science degree, preparing them for graduate or medical school admissions, and/or preparing them for careers in AD/ADRD research. Support for science teachers will be limited to those programs with a clear plan for how teachers will utilize their summer experience in their teaching during the school year, such as enhancing the STEM curriculum or increasing number of STEM courses taught. Focus on High School Students, Undergraduates, or Science Teachers: Science education research has demonstrated that early exposure to scientific research leads to the retention of trainees in science, technology, engineering, and mathematics (STEM). The President’s Council of Advisors on Science and Technology (PCAST) specifically highlights the need for retention of trainees in STEM by involving them in contemporary, hands-on research experiences especially during the first two years of college. Summer research experiences provide important experiential learning to sustain students interests in STEM and medicine careers. The short-term summer experience, in contrast to a year-long experience, allows for a focused and concentrated effort on instruction, and intentionally coincides with the time of year when the target populations of this program (i.e., high school students, undergraduate college students, and science teachers) would typically have the opportunity to engage in such a research educational experience. For the purpose of this announcement, institutions should explain how this program will be developed in a way that will foster diversity and inclusion at their organization. As indicated below, applicants must include a Recruitment Plan to Enhance Diversity which describes the program’s proposed recruitment efforts and how the proposed plan reflects past experiences in recruiting individuals from diverse backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences (see NOT-OD-20-031 for additional information on NIH's Notice of Interest in Diversity). All programs are expected to be inclusive, supportive, and safe, and to provide opportunities for participants to interact with investigators who could contribute to their growth. Applications from a variety of institutions, including those from minority serving institutions (MSIs), are encouraged. Applicants should consider how the developed programs can optimize participation and potentially include additional participants from outside the applicant institution, especially those in local and/or affiliated institutions. Applicants must demonstrate how this program will add significant value over existing programs at the applicant institution. Each institution must have a unique program structure that maximizes resources, departments, and faculty at the applicant institution to address the target population. Applicants are encouraged to propose collaborations with affiliated and/or local institutions, as appropriate. Applicants are also encouraged to partner with existing NIH-funded or other federally-funded resources and programs and leverage training activities from both federal and private-sector partners including, but not limited to, the following: Alzheimer's Disease Research Centers (ADRCs) Centers on the Demography and Economics of Aging Claude D. Pepper Older Americans Independence Center (OAIC) Edward R. Roybal Centers for Translation Research in the Behavioral and Social Sciences of Aging Nathan Shock Centers Resource Centers for Minority Aging Research (RCMAR) NCATS Clinical and Translational Science Awards (CTSA) Research Centers in Minority Institutions Program (RCMI) Non-Responsiveness Criteria Applications that propose programs primarily outside of AD/ADRD research, or have a general STEM focus, will be considered non-responsive to this FOA and will be withdrawn prior to review. Research education programs may complement ongoing research training and education occurring at the applicant institution, but the proposed educational experiences must be distinct from those training and education programs currently receiving Federal support. R25 programs may augment institutional research training programs (e.g., T32, T90), but cannot be used to replace or circumvent Ruth L. Kirschstein National Research Service Award (NRSA) programs,

With this solicitation, NIJ seeks applications for funding of rigorous, independent evaluation projects funded under the OJP Community-Based Violence Intervention and Prevention Initiative (CVIPI). This solicitation includes two funding categories: 1) Evaluation research of programmatic sites funded under the OJP FY23 and FY24 CVIPI solicitations; and 2) evaluation research of other community-violence programs.

This NOFO invites applications for the Nathan Shock Centers of Excellence in Basic Biology of Aging (NSC). These Center grants will provide funding for leadership, training, research, and outreach activities that will increase and disseminate scientific knowledge in areas supported by the NIA's Division of Aging Biology. The NSC were created in 1995 in honor of Nathan Shock, founding head of the NIH Gerontology Research Center. The NSC provide, both within and beyond their institutions, intellectual leadership and innovation; training; pertinent service cores focused on the needs of the field; and opportunities for research career development. They each collaborate substantially with other NSC and other NIA-funded Centers through the Research Centers Collaborative Network (RCCN). The NSC awards are intended for institutions committed to research on the basic biology of aging, The awards will facilitate further sustained progress on basic research on aging biology, either overall or on a key area within the field. Research Objectives To achieve the objectives above, applicants may propose a sustained research program focused on aging biology as a general term, or by identifying a well-defined and focused area within the field. If a focused research area is selected, service core activities (see below) should be consistent with that selection. Reviewers will be instructed to accept either approach (general or focused) as responsive to this NOFO. It is crucial to the design of each NSC that applicants specify the goals to be achieved within the five-year award period, to provide a plan to reach these goals, and to outline a method to evaluate progress toward these goals. The selection of core activities (see below) should follow from these considerations. Applications in response to this NOFO must include the following: Provide intellectual leadership in biology of aging research, serving as a resource for experimental design and guidance on the appropriate uses and limitations of aging metrics. Support multidisciplinary and translational research. Provide access to technologies through the cores. Develop technology (in the cores) for emerging areas of research in biology of aging. Leverage local institutional resources. Collaborate with other NSC and The Nathan Shock Centers Coordinating Center (NSC3) on multi-center research education, mentorship, and outreach programs. Interface with other NSC, the NSC3, and other NIH funded centers directly (as appropriate) or through the NIA-supported RCCN. To support these goals, each application must include the following: A core to support administrative functions. This core will manage outreach activities including courses, lectures and symposia – if such activities are proposed. This core will also be responsible for advertising the activities of the NSC, through development of a functional website, and participation in a common Data Coordination Center (see below). The leader of this core must be a PD/PI. A research development core to support pilot/feasibility projects, as well as provide support for investigators entering the field of biology of aging research. At least two research core activities uniquely focused on issues of interest to the biology of aging. These are further discussed below. Support for Research Each NSC may select an area of research focus from a broad range of topics, including, but not limited to, the following examples: Drivers of aging (often considered hallmarks); Metrics of aging, including biomarkers, clocks, computer-based modeling, imaging, etc.; Life course approaches to aging biology; Species-differences and similarities in aging; Medicinal chemistry for development of gerotherapeutics and geroprotective pharmacological interventions; Development and dissemination of new technologies to retain age-of-donor traits for in vitro systems; Facilitation of translation to clinical research; and Support for biology of aging research in IDeA states. Support for Outreach and Education Each NSC should place special emphasis on career development, engaging the public and providing education around the topic of aging biology, including, but not limited to the following examples: Mini-sabbaticals for mid-career and senior investigators (emphasizing new-to-aging research); Community engagement – inform about biology of aging and opportunities for citizen science; Webinars; and Symposia. Applicants must provide plans for the following elements: Leadership succession; Fostering an inclusive and accessible research training environment; and Evaluation: Applications must include a clear description of their objectives and a plan for evaluating the NSC, including all activities supported by the NSC, in line with the broader NSC program goals. The application must specify baseline metrics of NSC activities (e.g., numbers and characteristics of workshop participants, scientific dissemination, databases, networking opportunities with other funders, users of resources, etc.), as well as clearly defined milestones with metrics to gauge the short- or long-term success of the NSC in achieving its objectives. Wherever appropriate, applicants are encouraged to obtain feedback from participants to help identify weaknesses and to provide suggestions for improvements. The NSC evaluation plan should focus on the activities of the NSC, not the entire NSC program. NIH will evaluate the entire NSC program and NSC in five years, including the role of the NSC in fostering the success of the program. Based on the review, NIA will evaluate the effectiveness of the program, and determine whether to (a) continue the program as currently configured, (b) continue the program with modifications, or (c) discontinue the program after sunset and review period. Pre-Application Webinar A webinar is planned to provide prospective applicants the opportunity to understand and ask questions on the scientific scope of this NOFO and technical details for applying. The webinar will be open to all prospective applicants. Participation in the webinar is not a prerequisite to applying to this NOFO, but prospective applicants will need to register in order to participate. Prospective applicants are also encouraged to submit their questions in advance of the webinar; further details on where to submit the questions will be provided once the webinar has been scheduled. Please refer to the registration page for further details on the pre-application webinar, including the time and date and registration information.

The "Addressing Barriers to Healthcare Transitions for Survivors of Childhood and Adolescent Cancers" grant aims to fund research for developing and testing interventions that improve the transition from pediatric to adult healthcare for childhood and adolescent cancer survivors, with the goal of establishing best practices for their long-term care.

This funding opportunity provides financial support for small clinical trials focused on preventing and treating diseases related to diabetes, digestive, kidney, and urologic health, particularly targeting underserved populations to improve health outcomes.

The purpose of the Housing-related Hazards Capital Fund (HRHCF) Lead-based Paint Capital Fund Program (LBPCF) Notice of Funds Opportunity (NOFO) is to evaluate and reduce residential health hazards in public housing, including lead-based paint, carbon monoxide, mold, radon, fire safety, and asbestos. In accordance with Section 9 of the United States Housing Act of 1937 (42 U.S.C. 1437g) (1937 Act), and the Consolidated Appropriations Act, 2024, $65 million shall be made available for competitive grants to public housing agencies to evaluate and reduce housing-related hazards including lead-based paint in public housing, whereas no less than $25 million of the $65 million of the available funds shall be awarded for evaluating and reducing lead-based paint hazards specifically by carrying out the activities of lead-based risk assessments, inspections, abatement, interim controls, and clearance examinations. In the event there are not enough eligible applications to award $25 million in competitive grants to evaluate and reduce lead-based paint hazards, any remaining amounts may be awarded to qualified applicants for evaluating and reducing housing-related hazards. These amounts are combined with an additional $19.5 million in carryover funding from the Consolidated Appropriations Act, 2023 for lead-based paint and approximately $3.3 million in recaptured funds from the Consolidated Appropriations Act, 2021 for lead-based paint. Although two grant programs are combined under one funding opportunity title, applicants will request funding from each grant program separately per the program requirements and application submission guidelines. Applicants are entitled to apply for one grant program or both. Applications will be competitively scored based on the unique rating factors for each individual program and funding may be awarded, fully or partially, under one program, both, or neither based on the rating, ranking, and funding available under each program. If the applicant is applying for funding under both grant programs, the rating and rankings will be determined separately.

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits applications for identification of small molecules that function to elucidate the biology of disease as chemical probes or function as agonists or antagonists of disease target(s) for therapy or immunotherapy. The NOFO is intended to support discovery research for the identification of validated hits relevant to health-related outcomes of participating NIH Institutes. Stages of discovery research covered by this NOFO include: 1) assay development for specific biological targets and disease mechanisms relevant to the mission of participating NIH Institutes with the intent to screen for small molecule compounds that show potential as probes for use in advancing knowledge about the known targets, identifying new targets, or as pre-therapeutic leads; 2) screen implementation high throughput target-focused approaches or moderate throughput phenotypic- and fragment-based approaches to identify initial screening hits; 3) hit validation, including implementation of secondary assays that are orthogonal to the primary assay, advanced cheminformatics analysis and initial medicinal chemistry inspection to prioritize the hit set, and follow-up assays to characterize mode and mechanism of action of the validated hits; 4) hit-to-lead optimization, including SAR to optimize target engagement, selectivity and to minimize chemical liabilities, ADME, PK and PD studies, and, if appropriate, in vivo modeling to test efficacy or biological effects.

This funding opportunity supports research projects that explore the link between social isolation and suicide risk in older adults, encouraging innovative interventions and service delivery models to enhance social connections and mental health.

This grant provides funding for research teams to study how early-life social and environmental factors influence brain development and addiction risk using animal models and advanced neuroscience techniques.

This cooperative agreement establishes the Hepatitis C Training and Implementation Center (HC-TIC) Network, which aims to accelerate the integration of hepatitis C prevention, testing, care coordination, and treatment interventions (program implementation) in priority high-impact settings through training and implementation TA. This cooperative agreement will improve and sustain the quality, availability, and reach of hepatitis C prevention and care activities in priority high-impact settings. Protection of public health and safety through the control and prevention of disease, injury, and disability in the U.S. and worldwide with attention to infectious disease, food borne pathogens, environmental health, occupational safety and health, health promotion, injury prevention and educational activities.

This funding opportunity provides financial and technical assistance to partners for projects that restore aquatic connectivity and improve fish passage in rivers, floodplains, and coastal habitats, benefiting ecosystems and local communities.