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Grants for Small businesses - Federal

Explore 1,546 grant opportunities

Research and Development of Naval Power and Energy Systems (N00024-19-R-4145 Broad Agency Announcement (BAA))
Contact for amount
U.S. Department of Defense (Department of the Navy)
Federal

Application Deadline

Feb 6, 2028

Date Added

Aug 25, 2025

This grant provides funding for innovative research projects from industry and academia to improve naval shipboard power and energy systems, focusing on efficiency, resilience, and advanced technologies.

Science and Technology
For profit organizations other than small businesses
NIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 6, 2028

Date Added

Oct 24, 2024

This funding opportunity supports a wide range of organizations in planning and conducting clinical trials focused on improving dental, oral, and craniofacial health interventions.

Health
State governments
Forecast to Publish a Funding Opportunity Announcement for Integrative Neuroscience Initiative on Alcoholism (INIA) Consortia (U01 Clinical Trial Optional)
$10,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

May 1, 2026

Date Added

May 7, 2025

This funding opportunity supports collaborative research consortia focused on understanding the brain and body mechanisms involved in excessive alcohol use and Alcohol Use Disorder, aiming to improve prevention and intervention strategies.

Health
State governments
National Quantum and Nanotechnology Infrastructure
$10,000,000
National Science Foundation
Federal

Application Deadline

May 14, 2026

Date Added

Feb 16, 2026

This program provides funding to higher education institutions and their partners to create accessible research facilities for quantum and nanotechnology, supporting diverse users including underrepresented groups and small businesses across the U.S.

Science and Technology
Public and State controlled institutions of higher education
BRAIN Initiative: Reagent Resources for Brain Cell Type-Specific Access to Broaden Distribution of Enabling Technologies for Neuroscience (U24 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 15, 2027

Date Added

Sep 26, 2024

This funding opportunity provides financial support to U.S. institutions, particularly those historically underfunded, to produce and distribute specialized tools for neuroscience research focused on specific brain cell types.

Education
State governments
Engineering of Biomedical Systems
$10,400,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Jan 3, 2025

This grant provides funding for researchers to develop innovative engineering solutions that improve our understanding of biological systems and enhance medical diagnosis, treatment, and healthcare delivery.

Science and Technology
For profit organizations other than small businesses
NIH Science Education Partnership Award (SEPA)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jul 7, 2026

Date Added

May 29, 2025

This funding opportunity supports innovative educational projects that inspire pre-college students to pursue careers in STEM, particularly in biomedical and behavioral sciences, through engaging activities in both classroom and informal settings.

Education
State governments
FY2026 Research Opportunities in Accelerator Stewardship and Accelerator Development
$3,000,000
U.S. Department of Energy (Office of Science)
Federal

Application Deadline

May 21, 2026

Date Added

Mar 13, 2026

This funding opportunity provides financial support for research and development in accelerator technology, targeting academic institutions, national labs, and for-profit companies to advance innovations that benefit various scientific fields and enhance domestic manufacturing capabilities.

Science and Technology
Public and State controlled institutions of higher education
Biological Technologies
$2,000,000
U.S. Department of Defense (DARPA - Biological Technologies Office)
Federal

Application Deadline

Sep 30, 2026

Date Added

Oct 2, 2025

This grant provides funding for innovative research projects that utilize biological technologies to enhance U.S. national security, targeting a wide range of applicants including nonprofits, educational institutions, and businesses.

Science and Technology
Nonprofits
Applied Mathematics
Contact for amount
National Science Foundation
Federal

Application Deadline

Nov 16, 2026

Date Added

Mar 17, 2025

This funding opportunity supports researchers in mathematics who are working on innovative solutions to scientific and engineering challenges, while also promoting the training of emerging applied mathematicians.

Science and Technology
Public and State controlled institutions of higher education
Targeted Genome Editor Delivery (TARGETED) Challenge
$1,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

May 4, 2026

Date Added

Dec 24, 2025

This grant provides funding to researchers and innovators developing advanced delivery systems for genome editing technologies, particularly targeting hard-to-reach tissues and overcoming barriers like the blood-brain barrier.

Science and Technology
For profit organizations other than small businesses
Injury Prevention and Control Research and State and Community Based Programs - RFA-SH-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Oct 19, 2023

This funding opportunity provides financial support to a wide range of organizations, including state governments, universities, and nonprofits, to develop and implement programs focused on preventing injuries and promoting public health in communities across the U.S.

Health
State governments
Focused Technology Research and Development (R01 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 22, 2026

Date Added

Nov 15, 2024

This funding opportunity supports innovative projects that develop new tools and technologies to advance biomedical research, targeting a wide range of eligible applicants including universities, nonprofits, and businesses.

Health
State governments
Spurring Projects To Advance Energy Research And Knowledge Swiftly (SPARKS)
$500,000
U.S. Department of Energy (Advanced Research Projects Agency Energy)
Federal
Rolling

Application Deadline

Sep 30, 2029

Date Added

Nov 9, 2023

This funding opportunity supports innovative energy research projects that have the potential to significantly transform energy technologies, targeting a wide range of applicants including educational institutions, nonprofits, and small businesses.

Science and Technology
Individuals
Ocean Technology and Interdisciplinary Coordination
Contact for amount
National Science Foundation
Federal

Application Deadline

Feb 15, 2027

Date Added

Mar 5, 2025

This program provides funding for researchers to develop innovative oceanographic technologies and improve interdisciplinary collaboration in ocean science.

Science and Technology
Public and State controlled institutions of higher education
Rfa-Tp-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Nov 26, 2025

This funding opportunity provides financial support to a variety of organizations, including state governments, universities, and nonprofits, to implement innovative public health programs focused on preventing injuries and promoting safety in communities.

Health
State governments
Biophotonics
Contact for amount
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Apr 5, 2023

This funding opportunity supports innovative engineering research that combines photonics with biology and medicine to develop advanced diagnostic and therapeutic technologies.

Science and Technology
Private institutions of higher education
Academic-Industrial Partnerships (AIP) to Translate and Validate In Vivo Imaging Systems (R01 Clinical Trial Optional)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 5, 2026

Date Added

Nov 7, 2024

This funding opportunity supports collaborations between academic researchers and industry partners to develop and validate advanced imaging technologies that improve cancer detection and treatment.

Education
State governments
Chemical Screening and Optimization Facility (X01 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Apr 3, 2026

Date Added

May 19, 2023

This grant provides researchers with access to advanced facilities and technical support for developing non-hormonal contraception and reproductive health products, without direct funding.

Health
State governments
Long Range Broad Agency Announcement (LRBAA) 24-01
Contact for amount
U.S. Department of Homeland Security (DHS), Science and Technology Directorate (S&T)
Federal
Rolling

Application Deadline

May 31, 2029

Date Added

Mar 18, 2025

This grant invites industry and academic researchers to propose innovative solutions that enhance homeland security across various mission areas, including counterterrorism, cybersecurity, and public safety.

Science and Technology
For profit organizations other than small businesses