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Grants for Small businesses - Federal

Explore 1,577 grant opportunities

EDU Core Research
$2,500,000
National Science Foundation
Federal

Application Deadline

Oct 1, 2026

Date Added

May 23, 2025

This program provides funding for researchers to explore and improve STEM education, focusing on learning environments, broadening participation, and workforce development across various age groups and settings.

Education
Public and State controlled institutions of higher education
NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)
$249,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 12, 2028

Date Added

Jun 18, 2025

This funding opportunity supports dentist scientists with both clinical dental and research doctoral degrees, helping them transition from mentored postdoctoral training to independent research careers in dental, oral, and craniofacial health.

Health
Individuals
Limited Competition for the Continuation of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) Data Analysis Resource (U24 Clinical Trials Optional)
$600,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 1, 2026

Date Added

May 23, 2025

This funding opportunity supports research institutions and organizations in studying the long-term effects of adolescent alcohol use on brain development and health outcomes, aiming to improve prevention strategies for alcohol use disorders.

Health
State governments
Modular R01s in Cancer Control and Population Sciences (R01 Clinical Trial Optional)
$250,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 5, 2026

Date Added

Nov 8, 2024

This funding opportunity supports innovative research aimed at improving cancer prevention, control, and survivorship through interdisciplinary approaches in behavioral science, epidemiology, and data analytics, targeting a wide range of eligible applicants including universities, nonprofits, and small businesses.

Education
State governments
Automated Processes For Knowledge Discovery And Information Retrieval
$35,000,000
U.S. Department of Defense (Department of the Air Force)
Federal

Application Deadline

Sep 9, 2029

Date Added

Sep 22, 2025

This funding opportunity is designed to support U.S. entities, including universities, nonprofits, and businesses, in developing innovative technologies for analyzing and utilizing multi-source data to improve military decision-making and enhance national defense capabilities.

Science and Technology
Public and State controlled institutions of higher education
Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 18, 2027

Date Added

Oct 2, 2024

This funding opportunity supports researchers and organizations developing biologics-based therapies for nervous and neuromuscular disorders, facilitating their progression from early discovery to clinical trials.

Education
State governments
NSF Research: National Facilities
Contact for amount
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

May 21, 2024

This grant provides funding to research organizations for the operation of specialized national facilities that offer advanced scientific instruments and resources to support diverse research and educational initiatives across various scientific disciplines.

Science and Technology
Public and State controlled institutions of higher education
Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Assay Development and Neurotherapeutic Agent Identification (R61/R33 Clinical Trial Not Allowed)
$499,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 20, 2027

Date Added

Oct 23, 2024

This funding opportunity supports researchers in developing assays and identifying potential neurotherapeutic agents for neurological and neuromuscular disorders, facilitating early-stage drug discovery efforts.

Health
State governments
Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32) PA-25-168
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 25, 2027

Date Added

May 14, 2025

This grant provides funding to U.S. institutions to develop research training programs for predoctoral and postdoctoral students in biomedical and related fields, ensuring a skilled workforce to tackle health research challenges.

Education
State governments
FY 2026 Continuation of Solicitation for the Office of Science Financial Assistance Program
$5,000,000
U.S. Department of Energy (Office of Science)
Federal

Application Deadline

Sep 30, 2026

Date Added

Oct 1, 2025

This funding opportunity supports a wide range of fundamental scientific research projects across various disciplines, including energy, environment, and national security, aimed at advancing knowledge and innovation in the United States.

Science and Technology
Individuals
Research and Development of Naval Power and Energy Systems (N00024-19-R-4145 Broad Agency Announcement (BAA))
Contact for amount
U.S. Department of Defense (Department of the Navy)
Federal

Application Deadline

Feb 6, 2028

Date Added

Aug 25, 2025

This grant provides funding for innovative research projects from industry and academia to improve naval shipboard power and energy systems, focusing on efficiency, resilience, and advanced technologies.

Science and Technology
For profit organizations other than small businesses
Collaborative Awards to Support Microphysiological System Pilot Studies in Type 2 Diabetes Research
$1,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jul 5, 2026

Date Added

Sep 27, 2025

This funding opportunity supports collaborative pilot studies using advanced microphysiological systems to explore new approaches in understanding and treating type 2 diabetes, inviting a diverse range of applicants from various sectors.

Health
City or township governments
NIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 6, 2028

Date Added

Oct 24, 2024

This funding opportunity supports a wide range of organizations in planning and conducting clinical trials focused on improving dental, oral, and craniofacial health interventions.

Health
State governments
Forecast to Publish a Funding Opportunity Announcement for Integrative Neuroscience Initiative on Alcoholism (INIA) Consortia (U01 Clinical Trial Optional)
$10,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

May 1, 2026

Date Added

May 7, 2025

This funding opportunity supports collaborative research consortia focused on understanding the brain and body mechanisms involved in excessive alcohol use and Alcohol Use Disorder, aiming to improve prevention and intervention strategies.

Health
State governments
National Quantum and Nanotechnology Infrastructure
$10,000,000
National Science Foundation
Federal

Application Deadline

May 14, 2026

Date Added

Feb 16, 2026

This program provides funding to higher education institutions and their partners to create accessible research facilities for quantum and nanotechnology, supporting diverse users including underrepresented groups and small businesses across the U.S.

Science and Technology
Public and State controlled institutions of higher education
BRAIN Initiative: Reagent Resources for Brain Cell Type-Specific Access to Broaden Distribution of Enabling Technologies for Neuroscience (U24 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 15, 2027

Date Added

Sep 26, 2024

This funding opportunity provides financial support to U.S. institutions, particularly those historically underfunded, to produce and distribute specialized tools for neuroscience research focused on specific brain cell types.

Education
State governments
Prevention, Control, and Mitigation of Harmful Algal Blooms Program
$1,000,000
U.S. Department of Commerce (DOC NOAA - ERA Production)
Federal

Application Deadline

May 14, 2026

Date Added

Mar 16, 2026

This funding opportunity supports U.S.-based organizations in developing and testing technologies to combat harmful algal blooms, which threaten environmental and public health in coastal and freshwater ecosystems.

Science and Technology
Public and State controlled institutions of higher education
Engineering of Biomedical Systems
$10,400,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Jan 3, 2025

This grant provides funding for researchers to develop innovative engineering solutions that improve our understanding of biological systems and enhance medical diagnosis, treatment, and healthcare delivery.

Science and Technology
For profit organizations other than small businesses
NIH Science Education Partnership Award (SEPA)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jul 7, 2026

Date Added

May 29, 2025

This funding opportunity supports innovative educational projects that inspire pre-college students to pursue careers in STEM, particularly in biomedical and behavioral sciences, through engaging activities in both classroom and informal settings.

Education
State governments
FY2026 Research Opportunities in Accelerator Stewardship and Accelerator Development
$3,000,000
U.S. Department of Energy (Office of Science)
Federal

Application Deadline

May 21, 2026

Date Added

Mar 13, 2026

This funding opportunity provides financial support for research and development in accelerator technology, targeting academic institutions, national labs, and for-profit companies to advance innovations that benefit multiple scientific fields and enhance domestic manufacturing capabilities.

Science and Technology
Public and State controlled institutions of higher education