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Grants for Small businesses - Federal

Explore 1,577 grant opportunities

Environmental Engineering
$10,000,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Jun 2, 2025

This funding opportunity supports innovative research projects that aim to reduce pollution and improve environmental and human health through interdisciplinary approaches in environmental engineering.

Science and Technology
Nonprofits
Dynamics, Control and Systems Diagnostics
Contact for amount
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Mar 30, 2022

This funding opportunity supports researchers in engineering and related fields to explore and improve the behavior, diagnostics, and control of dynamic systems through innovative theoretical, computational, or experimental approaches.

Science and Technology
Public and State controlled institutions of higher education
Open Topics Broad Agency Announcement
$10,000,000
Strategic Environmental Research and Development Program
Federal

Application Deadline

Aug 21, 2026

Date Added

Aug 26, 2025

This funding opportunity supports private sector organizations, including small businesses and nonprofits, in developing innovative environmental technologies and methods to enhance military readiness and resilience for the U.S. Department of Defense.

Environment
For profit organizations other than small businesses
Clean Water State Revolving Fund (CWSRF)
Contact for amount
U.S. Environmental Protection Agency
Federal
Rolling

Application Deadline

Not specified

Date Added

Oct 9, 2025

This program provides low-interest loans to states and eligible entities for various water quality improvement projects, including wastewater treatment and stormwater management, to enhance public health and environmental sustainability.

Environment
Nonprofits
Innovative Solutions Opening
Contact for amount
US Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 5, 2029

Date Added

Jun 19, 2025

This funding opportunity is designed for innovators and organizations developing transformative healthcare technologies that enhance access and affordability, particularly in underserved areas.

Health
For profit organizations other than small businesses
NARMS Cooperative Agreement Program to Strengthen Antibiotic Resistance Surveillance in Retail Food Specimens
$200,000
U.S. Department of Health & Human Services (Food and Drug Administration)
Federal

Application Deadline

Apr 1, 2027

Date Added

Jul 12, 2025

This funding opportunity provides financial support to educational institutions, nonprofits, and government entities to enhance surveillance of antibiotic resistance in bacteria found in retail food, particularly raw meats and seafood.

Health
Public and State controlled institutions of higher education
Advanced Laboratories for Accelerating the Reach and Impact of Treatments for Youth and Adults with Mental Illness (ALACRITY) Research Centers (P50 Clinical Trial Optional)
$1,500,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

May 18, 2026

Date Added

Jun 20, 2023

This funding opportunity provides financial support for research centers focused on improving mental health treatments and services for youth and adults in the U.S. through innovative approaches and collaboration among diverse stakeholders.

Health
State governments
Summer Research Education Experience Program (R25 Clinical Trial Not Allowed)
$125,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 17, 2027

Date Added

Nov 1, 2024

This grant provides financial support for summer research programs designed to engage high school and undergraduate students, as well as science teachers, in hands-on biomedical and behavioral research experiences to inspire future careers in these fields.

Education
State governments
Substance Use/Substance Use Disorder Dissertation Research Award (R36 Clinical Trials Not Allowed)
$50,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 16, 2026

Date Added

Jan 3, 2025

This funding opportunity supports doctoral candidates conducting research on substance use and addiction, focusing on innovative approaches to prevention, treatment, and health disparities among underserved populations.

Education
State governments
Rfa-Cd-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Nov 26, 2025

This funding opportunity provides financial support for a wide range of public health initiatives focused on preventing and controlling injuries and violence through community and state-level interventions, targeting a diverse group of applicants including governments, universities, and nonprofits.

Health
State governments
Social disconnection and Suicide Risk in Late Life (R01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 5, 2026

Date Added

Nov 19, 2024

This funding opportunity supports research on how social isolation and loneliness affect suicide risk in older adults, aiming to identify protective factors and inform interventions for vulnerable populations.

Health
State governments
Clinical Validation of a Candidate Biomarker for Neurological or Neuromuscular Disorders (U01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 22, 2026

Date Added

Oct 3, 2024

This funding opportunity supports U.S.-based institutions and organizations in validating candidate biomarkers for neurological and neuromuscular disorders to improve clinical decision-making and therapeutic development.

Health
State governments
Pathways to Enable Secure Open-Source Ecosystems
$1,500,000
National Science Foundation
Federal

Application Deadline

Sep 1, 2026

Date Added

Feb 20, 2026

This program provides funding to U.S.-based organizations to develop secure and sustainable open-source ecosystems that enhance innovation in critical sectors like AI, cybersecurity, and healthcare.

Science and Technology
Public and State controlled institutions of higher education
Coordinating Austere Nodes through Virtualization and Analysis of Streams (CANVAS)
$3,000,000
U.S. Department of Defense (Air Force -- Research Lab)
Federal
Rolling

Application Deadline

May 22, 2029

Date Added

May 24, 2024

This grant seeks innovative research to develop a system that enables the Air Force to effectively manage and execute command and control operations across distributed locations in dynamic and contested environments.

Science and Technology
Nonprofits
Division of Chemistry: Disciplinary Research Programs
$105,000,000
National Science Foundation
Federal

Application Deadline

Sep 30, 2026

Date Added

Apr 26, 2023

This funding opportunity supports foundational research in various chemistry subfields for U.S. higher education institutions and nonprofit organizations, promoting advancements in areas like sustainability and advanced manufacturing.

Science and Technology
Public and State controlled institutions of higher education
Population Assessment of Tobacco and Health (PATH) Study Biospecimen Access (X01)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 30, 2026

Date Added

Aug 24, 2023

This funding opportunity provides researchers access to valuable biospecimens from a major study on tobacco use and health, enabling them to conduct important studies that support tobacco regulation and public health.

Education
State governments
Continuing Human Enabling Enhancing Restoring and Sustaining
Contact for amount
U.S. Department of Defense (Air Force -- Research Lab)
Federal

Application Deadline

Aug 22, 2044

Date Added

Aug 8, 2025

This funding opportunity supports a wide range of research and technology initiatives aimed at enhancing human performance and effectiveness for the Air Force, welcoming participation from various organizations, including universities and private firms.

Science and Technology
City or township governments
FY25 Long Range Broad Agency Announcement (BAA) for Navy and Marine Corps Science and Technology
Contact for amount
U.S. Department of Defense (Office of Naval Research)
Federal

Application Deadline

Sep 30, 2026

Date Added

May 30, 2025

This funding opportunity supports innovative research and technology development to enhance the operational capabilities of the Navy and Marine Corps, inviting proposals from academia, industry, and the research community worldwide.

Science and Technology
Nonprofits
Advanced Technological Education
$7,500,000
National Science Foundation
Federal

Application Deadline

Oct 1, 2026

Date Added

Jun 26, 2024

This program provides funding to two-year colleges and their partners to improve technician education in critical technology fields, focusing on workforce development and broadening participation in STEM for underserved communities.

Science and Technology
Public and State controlled institutions of higher education
Cyberinfrastructure for Public Access and Open Science (CI PAOS)
$600,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Apr 10, 2024

This funding initiative supports early-stage collaborative projects that enhance research data infrastructure and promote open science by bringing together researchers, data management professionals, and libraries to improve data accessibility and usability.

Science and Technology
Public and State controlled institutions of higher education