Grants for Small businesses - Federal
Explore 1,546 grant opportunities
Application Deadline
Jan 5, 2026
Date Added
Jun 19, 2025
This funding opportunity supports U.S.-based small businesses in collaborating with nonprofit research institutions to advance innovative health-related research and technology development.
Application Deadline
Feb 19, 2025
Date Added
Nov 5, 2024
This funding opportunity is designed for small businesses to develop affordable and innovative devices that can quickly and accurately detect both known and unknown drugs in biological samples, particularly in resource-limited settings like emergency departments and health centers.
Application Deadline
Mar 24, 2025
Date Added
Dec 20, 2023
This funding opportunity supports existing Centers for AIDS Research in expanding training and research initiatives focused on HIV and health disparities, particularly for underrepresented groups and early-career investigators.
Application Deadline
May 25, 2025
Date Added
Mar 3, 2023
This funding opportunity supports the creation of mentoring networks that provide professional development and career guidance for graduate students, postdoctoral scholars, and early-career researchers in mental health, helping them advance towards independent research careers.
Application Deadline
Feb 6, 2026
Date Added
Nov 8, 2024
This funding opportunity supports multi-center clinical trials aimed at improving treatments for neurological emergencies, such as traumatic brain injury and status epilepticus, by leveraging a collaborative network and infrastructure.
Application Deadline
Nov 15, 2024
Date Added
Oct 30, 2023
This grant provides funding for research on how HIV and substance use affect placental health and maternal outcomes, targeting a wide range of institutions and researchers focused on these critical health issues.
Application Deadline
May 8, 2024
Date Added
Sep 27, 2023
An Ideas Lab is an intensive meeting that brings together multiple diverse perspectives to focus on finding innovative cross-disciplinary solutions to a grand challenge problem (see below and PAPPG Chapter II.F.6. for more information about this type of proposal). The goal of the Personalized Engineering Learning Ideas Lab is to extend engineering education research to enable advanced personalization in pedagogy and assessment in a K-12 or higher education context. The following broad areas have been identified as possible avenues to advance knowledge: personalized engineering education, multimodal sensing for personalized learning systems and team-based personalized learning. This Ideas Lab aims to bring together experts from diverse scientific, engineering and education backgrounds to develop innovative technologies and solutions to achieve personalized learning for engineering education. This Ideas Lab is organized by the Office of Emerging Frontiers and Multidisciplinary Activities (EFMA), the Division of Engineering Education and Centers (EEC), and the Division of Civil, Mechanical and Manufacturing Innovation in the Directorate for Engineering (ENG); the Division of Information and Intelligent Systems (IIS) in the Directorate for Computer and Information Science and Engineering (CISE); the Division of Behavioral and Cognitive Sciences in the Directorate for Social, Behavioral and Economic Sciences (SBE); the Division of Graduate Education, the Division of Research on Learning in Formal and Informal Settings, and the Division of Undergraduate Education in the Directorate for STEM Education (EDU); and the Division of Translational Impacts in the Directorate for Technology, Innovation and Partnerships (TIP). INFORMATIONAL WEBINAR: The Emerging Frontiers and Multidisciplinary Activities (EFMA) Office will host an informational webinar in October 2023 to discuss the Ideas Lab: Personalized Engineering Learningsolicitationandtoanswer questions. Details on how to join this webinar will be posted on the EFMA Website.
Application Deadline
Oct 1, 2025
Date Added
May 27, 2025
This funding opportunity supports innovative research projects aimed at improving the understanding, prevention, and treatment of melanoma, particularly for military and Veteran populations.
Application Deadline
Apr 11, 2025
Date Added
Jan 16, 2025
This funding opportunity provides financial support for universities, businesses, and organizations to develop and implement innovative technologies that convert carbon dioxide into useful products, helping to combat climate change and promote sustainability.
Application Deadline
Feb 28, 2025
Date Added
Dec 13, 2024
This funding opportunity provides financial support to local Philippine organizations to strengthen the country's capacity to prevent and respond to infectious disease threats through a collaborative, multi-sectoral approach.
Application Deadline
Dec 2, 2024
Date Added
Aug 19, 2024
This funding opportunity supports small businesses in developing innovative technologies and services for population-wide genomic screening to improve primary care for common genetic conditions.
Application Deadline
Nov 13, 2024
Date Added
Oct 1, 2024
This grant provides funding for researchers to analyze and interpret data from various NASA planetary missions, encouraging innovative scientific investigations and collaborations in the field.
Application Deadline
Sep 25, 2025
Date Added
May 22, 2025
This funding opportunity supports the development and enhancement of animal models and related biological tools that are broadly applicable to various areas of biomedical research, aimed at improving our understanding of human diseases and advancing therapeutic interventions.
Application Deadline
Nov 7, 2024
Date Added
Feb 8, 2023
This funding opportunity announcement (FOA) encourages applications for multi-center clinical trials focused on neurological emergencies. Successful applicants will collaborate and conduct the trial within the NIH SIREN Network. The NIH SIREN Clinical Coordinating Center (CCC) will work with the successful applicants to implement the proposed trial efficiently and the SIREN Data Coordinating Center (DCC) will provide statistical and data management support. The NIH SIREN hubs and their affiliated clinical sites will provide on-site implementation of the clinical protocols.The NIH SIREN Network will also be uniquely poised to collaborate with other US and international consortia necessary to conduct larger, definitive trials of promising interventions for neurological emergencies.Multi-center clinical trials in stroke treatment, recovery, or prevention supported by NINDS will be conducted in the NIH StrokeNet, and not within SIREN. Applicants do not need to be part of the existing SIREN infrastructure to apply under this FOA.
Application Deadline
Aug 26, 2024
Date Added
May 9, 2024
The FY24 MRP Idea Award supports innovative, untested, exploratory, high-risk/potentially high-reward concepts, theories, paradigms, and/or methods that address at least one of the FY24 MRP Focus Areas in Section II.A.1. Key aspects of the Idea Award: The intent of the Idea Award is to generate novel research avenues for investigation; therefore, novelty and innovation should be key aspects of the proposed research. Research supported by the Idea Award must introduce a new paradigm, challenge existing paradigms, look at existing problems from new perspectives, or exhibit other highly creative qualities. The proposed project must be exploratory, hypothesis-driven, or hypothesis-generating research and be based on a well-developed study design and plan of analysis. Principal Investigators (PIs) new to the melanoma field are encouraged to apply. The Idea Award is NOT intended to expand or extend previously published findings or continue a line of research already established and /or funded in the PIs laboratory. Incremental advances, the next logical step, or merely switching the object or method of inquiry from one cancer to melanoma is not considered innovative. The expected outcome of research supported by this award is the generation of robust preliminary data to be used as a foundation for future melanoma-focused research projects. Inclusion of preliminary data is discouraged. PIs proposing projects already supported by significant preliminary data and/or other funding sources should consider applying to other FY24 MRP funding opportunities for which the inclusion of preliminary data is more appropriate or required. Inclusion of preliminary data other than serendipitous findings is not consistent with the exploratory/innovative nature of this award. If preliminary data are included, they should be unanticipated outcomes or results from an unrelated project or study.
Application Deadline
Oct 3, 2025
Date Added
Jan 2, 2025
This funding opportunity is designed for researchers with existing NCI R01 grants to integrate innovative cancer research technologies into their projects, enhancing the study's impact and advancing the field of cancer research.
Application Deadline
Jun 17, 2024
Date Added
Mar 26, 2024
The FY24 LCRP Career Development Award supports early-career, independent investigators to conduct impactful research under the mentorship of an experienced lung cancer researcher as an opportunity to obtain the funding, mentoring, and experience necessary for productive, independent careers at the forefront of lung cancer research. Research applications only in the area of mesothelioma will not be accepted. This award is intended to support impactful research projects with an emphasis on discovery.Preliminary data are not required. However, logical reasoning and a sound scientific rationale for the proposed research must be demonstrated.Key elements of this award are as follows:Principal Investigator (PI): PIs must be research- or physician-scientists at an early stage of their independent research careers. PIs must be within 5 years of their first faculty appointment (or equivalent) and exhibit a strong desire to pursue a career in lung cancer research.Mentorship: The Mentor(s) must be an experienced lung cancer researcher(s) as demonstrated by a strong record of funding and publications in lung cancer research. In addition, the Mentor(s) must demonstrate a commitment to developing the PIs career in lung cancer research.Career Development: A Career Development Plan is required and should be prepared with appropriate guidance from the Mentor(s). A clearly articulated strategy for acquiring the necessary skills, competence, and expertise to have a career at the forefront of lung cancer research should be included. The plan should outline how the PI will gain experience in lung cancer research. Because career development is the focus of this award, the PI must commit a minimum of a 25% level of time and effort during the period of performance to conduct lung cancer research under this award.Impact: Research that has high potential impact may lead to major advancements and significantly accelerate progress toward eradicating deaths and suffering from lung cancer.Relevance to Military Health System (MHS) Beneficiaries: The application should clearly articulate how the proposed research is relevant to Service Members, Veterans, and their Families.The PI is required to attend a Department of Defense (DOD) one day in progress review meeting prior to the end of the second year of the award.
Application Deadline
Not specified
Date Added
Jun 24, 2024
This grant provides funding to small businesses for pre-clinical research projects that have previously received Phase II SBIR or STTR awards, helping them advance promising biotechnology products towards commercialization.
Application Deadline
Jan 30, 2026
Date Added
Dec 24, 2025
This competition provides $100,000 in funding to individuals and organizations in the U.S. to develop innovative electric power distribution systems that can adapt to modern energy challenges in rural, suburban, and urban settings.
Application Deadline
Nov 26, 2025
Date Added
May 28, 2025
This funding opportunity provides financial support for research projects that aim to reduce health disparities in rural communities by implementing targeted interventions and engaging local resources.


