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Grants for Small businesses - Federal

Explore 1,552 grant opportunities

Engineer Research and Development Center (ERDC) - Construction Engineering Research Laboratory (CERL) - Commercial Solutions Opening (CSO)
Contact for amount
U.S. Department of Defense (Engineer Research and Development Center)
Federal

Application Deadline

Not specified

Date Added

Apr 30, 2025

This grant seeks innovative commercial solutions from a wide range of organizations to enhance military and civilian infrastructure, focusing on sustainability, energy efficiency, and advanced construction technologies.

Science and Technology
For profit organizations other than small businesses
Fostering Civic Engagement, Democratic Participation, and Youth Leadership
$150,000
DOS-POL (U.S. Mission to Poland)
Federal

Application Deadline

Jul 12, 2024

Date Added

May 17, 2024

PROJECT OBJECTIVES: PDS Poland invites proposals to equip the next generation of Polish leaders (aged 15 30) to implement impactful civic engagement programs focused on the promotion of human rights, democratic values, and the rule of law. Activities should equip participants with skills to successsfully navigate the complexities of their society, engage constructively, and contribute meaningfully to their communitys development and Polands future. Projects should also be designed with the intent of fostering enduring connections and collaboration among participants after the projects conclusion. PRIORITY PROGRAMMING AREAS: A successful proposal will include a comprehensive calendar of activities up to 36 months that include the following three elements: 1. A series of skills-building workshops and/or interactive trainings; 2. Support for implementation of participant-led community projects; 3. A minimum of 12 months of ongoing mentoring and networking opportunities for participants following the completion of elements 1 and 2 above. All projects must address the development of youth leadership, critical thinking, project management skills, and resilience as well as at least one of below programming areas: Human Rights Engagement and Problem-Solving: Initiatives promoting human rights and tolerance, focused on active community engagement, including local analysis of challenges and identification of solutions. Promoting Democratic Participation: Programs that encourage democratic involvement, and increase youth participation in the public policy process, including collaboration with local governments, communities, NGOs, civil society organizations, and/or the private sector. Programs should focus on teaching advocacy skills and the formulation of policy reforms to develop strategies addressing local issues to affect meaningful change. Inclusive Engagement: Strategies for engaging typically civically inactive youth and ensuring that the needs and rights of minority communities are considered in building safe and tolerant environments. Examples of types of activities that can be included in proposals: 1. Projects organized and carried out by youth (aged 15 - 30) that focus on the themes mentioned above. Initiatives aimed at empowering young people by providing them with the necessary skills and knowledge to effectively plan and execute community projects. 2. Programs that train educators to equip young people (aged 15 - 30) with the necessary skills (including resilience) to carry out civic engagement projects (this type of activity must include a youth-implemented project) in their communities. 3. Mentoring and networking events. PDS Poland welcomes proposals that incorporate the involvement of U.S. experts, trainers, models, and/or best practices, as appropriate. Participants and Audiences: Proposals should describe both the primary and secondary audiences for the program, including anticipated numbers to be reached. Primary audiences are those who will participate directly in the program, while secondary audiences are those who will be reached by the projects primary audiences as a result of their participation (For example, a workshop for educators would have teachers as the primary audience and the students in their classrooms organizing a civic engagement project in their local communities as the secondary audience). Programs ensuring gender parity and socio-economic inclusion across all its activities are encouraged. Applicants should be as specific as possible in their proposals about their projects primary audience and how they will engage them through programming. The principal method of engagement will be through in-person programming. Virtual engagement may be a part of the overall strategy, augmenting in-person programming. Additional proposal elements to note: The grantee is expected to lead recruitment efforts of program participants, ensuring DEIA (diversity, equity, inclusion, and access) principles are promoted in the recruitment process. U.S. Mission Poland will amplify program opportunities on its social media platforms. The language of instruction can be English and/or Polish. The proposal must include detailed information about the project members/coordinators, including CV and other relevant professional experience. The trainers or facilitators of the program should be experienced professionals working in the field. The proposal must include a proposed activity schedule and monitoring and evaluation plan to measure program impact. Marketing and outreach strategies to recruit target program participants are required. Activities that are not typically funded include, but are not limited to: Projects that are inherently political in nature or that contain the appearance of partisanship/support to individual or single party electoral campaigns; Projects that support specific religious activities; Exchange programs; including travel to the U.S. Social welfare projects; Trade activities; fundraising campaigns; commercial projects; scientific research; construction projects; projects whose primary aim is the institutional development of the organization itself; Conferences, lectures, scientific research, studies, etc.; Book publishing or translation for the purposes of publishing a book; Ongoing salary costs of organization staff; Equipment, including but not limited to, cameras and for the office; and Food and drink beyond the cost of coffee breaks and working lunches (alcohol will not be funded).

International Development
Nonprofits
NCI Small Grants Program for Cancer Research for Years 2023, 2024, and 2025 (NCI Omnibus) (R03 Clinical Trial Optional)
$50,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 7, 2025

Date Added

Dec 5, 2022

This grant provides funding for small-scale cancer research projects that can be completed in two years, aimed at supporting innovative studies and methodologies in various areas of cancer research.

Education
State governments
Addressing Health and Health Care Disparities among Sexual and Gender Minority Populations (R01 - Clinical Trials Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 24, 2025

Date Added

Nov 30, 2023

This funding opportunity supports researchers working to identify and address health and healthcare disparities affecting sexual and gender minority populations, particularly those from racial/ethnic minority and lower socioeconomic backgrounds.

Education
State governments
CoasterChase
$25,000,000
U.S. Department of Defense (DARPA - Biological Technologies Office)
Federal

Application Deadline

Aug 28, 2025

Date Added

Jun 27, 2025

This grant provides funding for innovative research to develop ingestible devices that can sense and stimulate the gut's nervous system to improve stress responses and enhance the performance of military personnel.

Science and Technology
Public and State controlled institutions of higher education
Alumni Engagement Innovation Fund 2025 - Brazil
$35,000
U.S. Department of State (U.S. Mission to Brazil)
Federal

Application Deadline

Jan 10, 2025

Date Added

Nov 19, 2024

This funding opportunity supports alumni of U.S. government-sponsored exchange programs in Brazil to develop community projects that promote democracy, human rights, economic partnerships, and environmental protection, while emphasizing diversity and inclusion.

Other
Small businesses
DoD, Melanoma, Melanoma Academy Scholar Award
$2,640,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Aug 26, 2024

Date Added

May 9, 2024

Key aspects of the MASA: Principal Investigator: The PI (i.e., Scholar) must be an early-career researcher or physician-scientist no more than 7 years from obtaining their first faculty-level appointment. Postdoctoral fellows (and equivalent) are not eligible for this award mechanism. The PIs record of accomplishments and the proposed research will be evaluated regarding their potential for contributing to the FY24 MRP Focus Area(s) in Section II.A.1. Not all of the PIs accomplishments need to be in the field of melanoma. The PIs organization must demonstrate a commitment to the PI through confirmation of independent laboratory space. Impact: The impact of the proposed research must relate to at least one of the FY24 MRP Focus Areas in Section II.A.1. Impactful research, including basic research, should expedite the advancement of promising ideas towards clinical and/or public utility. The application must articulate the short- and long-term impact the proposed research will have on melanoma research and/or patient care. Career Development: A Career Development and Sustainment Plan (Attachment 7) is required and should be prepared with appropriate guidance from the Career Guide. The Career Development and Sustainment Plan should include a clearly articulated strategy for establishing collaborations and acquiring the necessary skills, competencies, and expertise to advance and sustain an independent career at the forefront of the melanoma field. The Scholar must show milestones and career pathways toward achieving the milestones. The Scholar must articulate commitment to interactions with the MA. Career Guide: The Scholar must designate a Career Guide. The Career Guide must be an experienced melanoma researcher, as demonstrated by a strong record of funding and publications in melanoma. In addition, the Career Guide must demonstrate a commitment to advancing the Scholars career in the melanoma field. The Career Guide must also be committed to fully participating in the MA throughout the award period of performance, including interacting with other MA Scholars and Career Guides and participating in MA activities (e.g., serving on the MA Advisory Board) as requested by MA Leadership. The Career Guide must not be the named Career Guide on any previously funded (FY21-FY23) MASA applications, nor may a Career Guide be named on more than ONE FY24 MASA application. Preliminary Data NOT Required: Preliminary data are not required. However, any unpublished, preliminary data presented should originate from the laboratory of the PI or a member of the research team.

Science and Technology
Nonprofits
DOD Glioblastoma, Resource Development Award
$500,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Nov 20, 2024

Date Added

Sep 17, 2024

This grant provides funding for researchers to develop and improve preclinical models that better mimic glioblastoma biology, with the goal of enhancing research and treatment outcomes for this aggressive brain cancer.

Science and Technology
Nonprofits
NIA Program Project Applications (P01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 25, 2025

Date Added

May 22, 2025

This funding opportunity supports collaborative research projects focused on aging and age-related diseases, aimed at institutions and organizations dedicated to improving the health and well-being of older adults.

Health
State governments
Investigational New Drug (IND)-enabling and Early-Stage Development of Medications to Treat Alcohol Use disorder and Alcohol-Associated Organ Damage (U43/U44 Clinical Trial Optional)
$1,500,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Dec 4, 2024

Date Added

Jan 21, 2022

This funding opportunity provides financial support to small businesses developing new medications for treating alcohol use disorder and related organ damage, helping them advance their research towards FDA approval.

Health
Small businesses
NIDDK Centers for Diabetes Translation Research (P30 Clinical Trial Optional)
$400,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 10, 2025

Date Added

Dec 10, 2024

This funding opportunity supports the establishment of research centers that focus on translating diabetes prevention and treatment innovations into real-world practices, particularly for underserved populations facing health disparities.

Food and Nutrition
State governments
NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 5, 2026

Date Added

Jun 19, 2025

This funding opportunity supports U.S.-based small businesses in collaborating with nonprofit research institutions to advance innovative health-related research and technology development.

Health
Small businesses
Addressing Challenges in Detecting New Drugs: Instrumentation for Alternative Analytical Methods (R43/R44 - Clinical Trials Optional)
$3,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 19, 2025

Date Added

Nov 5, 2024

This funding opportunity is designed for small businesses to develop affordable and innovative devices that can quickly and accurately detect both known and unknown drugs in biological samples, particularly in resource-limited settings like emergency departments and health centers.

Education
Small businesses
Limited Competition: Revision Applications of Existing NIH Centers for AIDS Research (CFAR) and Developmental Centers for AIDS Research (D-CFAR) Grants (P30 Clinical Trial Not Allowed)
$1,500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 24, 2025

Date Added

Dec 20, 2023

This funding opportunity supports existing Centers for AIDS Research in expanding training and research initiatives focused on HIV and health disparities, particularly for underrepresented groups and early-career investigators.

Health
Small businesses
NIMH Mentoring Networks for Mental Health Research Education (R25 Clinical Trial Not Allowed)
$200,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

May 25, 2025

Date Added

Mar 3, 2023

This funding opportunity supports the creation of mentoring networks that provide professional development and career guidance for graduate students, postdoctoral scholars, and early-career researchers in mental health, helping them advance towards independent research careers.

Health
State governments
NIH SIREN Neurologic Clinical Trials (UG3/UH3 - Clinical Trial Required) PAR-25-049
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 6, 2026

Date Added

Nov 8, 2024

This funding opportunity supports multi-center clinical trials aimed at improving treatments for neurological emergencies, such as traumatic brain injury and status epilepticus, by leveraging a collaborative network and infrastructure.

Health
State governments
Effect of HIV and Substance Use Comorbidity on the Placenta and Maternal Outcomes (R01 Clinical Trial Optional)
$2,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 15, 2024

Date Added

Oct 30, 2023

This grant provides funding for research on how HIV and substance use affect placental health and maternal outcomes, targeting a wide range of institutions and researchers focused on these critical health issues.

Education
State governments
Ideas Lab: Personalized Engineering Learning
$3,000,000
National Science Foundation
Federal

Application Deadline

May 8, 2024

Date Added

Sep 27, 2023

An Ideas Lab is an intensive meeting that brings together multiple diverse perspectives to focus on finding innovative cross-disciplinary solutions to a grand challenge problem (see below and PAPPG Chapter II.F.6. for more information about this type of proposal). The goal of the Personalized Engineering Learning Ideas Lab is to extend engineering education research to enable advanced personalization in pedagogy and assessment in a K-12 or higher education context. The following broad areas have been identified as possible avenues to advance knowledge: personalized engineering education, multimodal sensing for personalized learning systems and team-based personalized learning. This Ideas Lab aims to bring together experts from diverse scientific, engineering and education backgrounds to develop innovative technologies and solutions to achieve personalized learning for engineering education. This Ideas Lab is organized by the Office of Emerging Frontiers and Multidisciplinary Activities (EFMA), the Division of Engineering Education and Centers (EEC), and the Division of Civil, Mechanical and Manufacturing Innovation in the Directorate for Engineering (ENG); the Division of Information and Intelligent Systems (IIS) in the Directorate for Computer and Information Science and Engineering (CISE); the Division of Behavioral and Cognitive Sciences in the Directorate for Social, Behavioral and Economic Sciences (SBE); the Division of Graduate Education, the Division of Research on Learning in Formal and Informal Settings, and the Division of Undergraduate Education in the Directorate for STEM Education (EDU); and the Division of Translational Impacts in the Directorate for Technology, Innovation and Partnerships (TIP). INFORMATIONAL WEBINAR: The Emerging Frontiers and Multidisciplinary Activities (EFMA) Office will host an informational webinar in October 2023 to discuss the Ideas Lab: Personalized Engineering Learningsolicitationandtoanswer questions. Details on how to join this webinar will be posted on the EFMA Website.

Science and Technology
For profit organizations other than small businesses
DoD Melanoma, Idea Award
$560,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Oct 1, 2025

Date Added

May 27, 2025

This funding opportunity supports innovative research projects aimed at improving the understanding, prevention, and treatment of melanoma, particularly for military and Veteran populations.

Science and Technology
Nonprofits
Bipartisan Infrastructure Law (BIL) Accelerating CO2 Conversion Technology Development and Deployment Biological, Catalytic, and Mineralization Pathways
$8,000,000
U.S. Department of Energy (National Energy Technology Laboratory)
Federal

Application Deadline

Apr 11, 2025

Date Added

Jan 16, 2025

This funding opportunity provides financial support for universities, businesses, and organizations to develop and implement innovative technologies that convert carbon dioxide into useful products, helping to combat climate change and promote sustainability.

Energy
Public and State controlled institutions of higher education