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Grants for Small businesses - Federal

Explore 1,545 grant opportunities

Research Experiences for Undergraduates
$155,000
National Science Foundation
Federal

Application Deadline

Aug 19, 2026

Date Added

Aug 30, 2024

This program provides funding for colleges and universities to engage undergraduate students in hands-on research experiences across various scientific fields, with a focus on supporting those from underrepresented backgrounds and institutions with limited STEM opportunities.

Education
Public and State controlled institutions of higher education
The Genesis Mission: Transforming Science and Energy with AI
$5,000,000
U.S. Department of Energy (Office of Science)
Federal

Application Deadline

Dec 17, 2026

Date Added

Mar 18, 2026

This funding opportunity provides financial support for interdisciplinary teams to develop and implement advanced AI technologies that drive scientific discovery and innovation in energy, environment, and national security.

Science and Technology
For profit organizations other than small businesses
U.S. Army Combat Capabilities Development Command Soldier Center Broad Agency Announcement for Basic and Applied Research
Contact for amount
U.S. Army Combat Capabilities Development Command Soldier Center
Federal
Rolling

Application Deadline

Feb 27, 2030

Date Added

Mar 18, 2025

This funding opportunity is designed to support universities, research institutes, and businesses in developing innovative technologies to enhance soldier performance and address future military challenges.

Science and Technology
Public and State controlled institutions of higher education
Injury Prevention and Control Research and State and Community Based Programs - RFA-PS-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Oct 20, 2023

This funding opportunity provides financial support for state, academic, non-profit, and business organizations to conduct research and implement programs focused on preventing and controlling injuries within communities.

Health
State governments
CHIPS Incentives Program Facilities for Semiconductor Materials and Manufacturing Equipment
Contact for amount
U.S. Department of Commerce (National Institute of Standards and Technology)
Federal

Application Deadline

Nov 1, 2026

Date Added

Oct 17, 2025

This program provides federal funding to private-sector organizations, nonprofits, and consortia for the construction and modernization of facilities that produce semiconductor materials and manufacturing equipment, aiming to strengthen U.S. semiconductor manufacturing and security.

Science and Technology
For profit organizations other than small businesses
Informatics, Coordination and Service Center for the Mutant Mouse Resource and Research Centers (U42 Clinical Trial Not Allowed)
$2,600,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

May 1, 2026

Date Added

Jun 10, 2025

This funding opportunity supports the development and management of a centralized service center that provides genetically engineered mouse models and enhances research coordination, data sharing, and innovative methodologies in biomedical research.

Health
State governments
Continuation or Revision of NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UH3 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 6, 2028

Date Added

Oct 11, 2024

This funding opportunity supports ongoing clinical trials aimed at improving the diagnosis, prevention, and treatment of dental, oral, and craniofacial diseases, encouraging applications from a wide range of eligible institutions and organizations.

Health
State governments
Long Range Broad Agency Announcement (BAA) for NSWC Crane
Contact for amount
U.S. Department of Defense (NSWC CRANE - N00164)
Federal
Rolling

Application Deadline

Not specified

Date Added

Aug 12, 2024

This funding opportunity invites innovative research proposals from academic institutions, industry partners, and research organizations to develop advanced technologies that support national security in areas like electronic warfare and hypersonic weapons.

Science and Technology
For profit organizations other than small businesses
Leveraging Nursing Research to Advance Healthy School Environments for All
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Apr 27, 2026

Date Added

May 29, 2025

This funding opportunity supports a variety of organizations in conducting research to improve health and educational outcomes for youth by creating healthier school environments.

Health
State governments
Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH3 Clinical Trials Not Allowed)
$250,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 14, 2026

Date Added

Oct 16, 2024

Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH3 Clinical Trials Not Allowed) aims to support the clinical validation of already analytically validated biomarkers and assays for cancer detection, diagnosis, and treatment monitoring, ensuring they are reliable and ready for use in clinical studies without conducting new trials.

Education
State governments
FY 2024 2026 Broad Agency Announcement (BAA), National Marine Fisheries Service
Contact for amount
U.S. Department of Commerce (DOC NOAA - ERA Production)
Federal

Application Deadline

Sep 30, 2026

Date Added

Jul 30, 2024

This funding opportunity supports innovative projects and research aimed at sustainable fisheries management, protected species recovery, and marine ecosystem enhancement, targeting a wide range of applicants including educational institutions, nonprofits, and government entities.

Environment
State governments
Information Innovation Office (I2O) Office-Wide
Contact for amount
U.S. Department of Defense (DARPA - Information Innovation Office)
Federal

Application Deadline

Nov 30, 2026

Date Added

Dec 1, 2025

This funding opportunity invites innovative research proposals from a wide range of organizations, including universities and small businesses, to develop groundbreaking technologies in information and computational science that enhance national security.

Science and Technology
For profit organizations other than small businesses
ROSES25: B.6 Heliophysics Technology and Instrument Development for Science
$2,350,000
National Aeronautics and Space Administration (NASA Headquarters)
Federal

Application Deadline

Apr 15, 2026

Date Added

Jan 13, 2026

This grant provides funding for universities and nonprofits to develop innovative technologies and instruments that advance research in solar and space physics, supporting NASA's goals for future space exploration.

Science and Technology
Public and State controlled institutions of higher education
NIGMS National and Regional Resources (R24 - Clinical Trial Not Allowed) PAR-25-416
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 14, 2027

Date Added

May 14, 2025

This funding opportunity supports the development and maintenance of shared biomedical research resources that provide advanced technologies and services to researchers across multiple states or nationally, ensuring broad access for academic investigators.

Science and Technology
State governments
Animal and Biological Material Resource Centers (P40 Clinical Trial Not Allowed)
$650,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 26, 2028

Date Added

Jun 10, 2025

This funding opportunity provides support for specialized research centers that develop and maintain laboratory animal colonies and biological materials, promoting scientific rigor and accessibility for researchers across the U.S. biomedical community.

Health
State governments
Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed)
$4,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jul 17, 2026

Date Added

Dec 6, 2024

This funding opportunity supports researchers in utilizing existing datasets to advance the understanding of substance use behaviors and related health issues, particularly focusing on critical health disparities and innovative analytical approaches.

Health
Public and State controlled institutions of higher education
Make America Healthy Again - Enhancing Lifestyle and Evaluating Value-based Approaches Through Evidence
$3,300,000
U.S. Department of Health and Human Services (Center for Medicare and Medicaid Services)
Federal

Application Deadline

May 15, 2026

Date Added

Mar 16, 2026

This funding opportunity supports a variety of organizations in implementing and evaluating innovative lifestyle medicine interventions to improve health outcomes and reduce costs for Medicare beneficiaries.

Health
Nonprofits
Fundamental Research to Counter Weapons of Mass Destruction
$2,500,000
U.S. Department of Defense (Defense Threat Reduction Agency)
Federal

Application Deadline

Sep 30, 2034

Date Added

Oct 2, 2024

This funding opportunity supports innovative research to develop strategies and technologies for countering threats from weapons of mass destruction, targeting a wide range of applicants including universities, nonprofits, and businesses.

Science and Technology
Public and State controlled institutions of higher education
Injury Prevention and Control Research and State and Community Based Programs - RFA-GH-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Oct 13, 2023

This funding opportunity provides financial support to a wide range of organizations, including state governments, universities, and non-profits, to develop and implement innovative programs focused on preventing and controlling injuries at the community level across the United States.

Health
County governments
Rfa-Cc-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Nov 26, 2025

This funding opportunity provides financial support to a wide range of organizations, including states, universities, and nonprofits, to implement evidence-based initiatives aimed at preventing injuries and improving public health outcomes.

Health
State governments