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Grants for Small businesses - Federal

Explore 1,549 grant opportunities

Traumatic Brain Injury Model Systems National Data and Statistical Center
$800,000
U.S. Department of Health and Human Services (Administration for Community Living)
Federal

Application Deadline

Not specified

Date Added

Sep 8, 2025

This grant provides funding to a variety of organizations to establish a national data center that will enhance research and improve rehabilitation services for individuals with traumatic brain injuries.

Science and Technology
State governments
Efficient and Innovative Natural History Studies Addressing Unmet Needs in Rare Diseases (R01 Clinical Trials Optional)
$400,000
U.S. Department of Health & Human Services (Food and Drug Administration)
Federal

Application Deadline

Not specified

Date Added

Jul 12, 2025

This funding opportunity provides financial support for innovative research studies aimed at improving understanding and treatment of rare diseases, targeting a wide range of eligible applicants including universities, nonprofits, and businesses.

Health
Public and State controlled institutions of higher education
Prevention, Control, and Mitigation of Harmful Algal Blooms Program
$1,000,000
U.S. Department of Commerce (DOC NOAA - ERA Production)
Federal

Application Deadline

May 14, 2026

Date Added

Mar 16, 2026

This funding opportunity supports U.S.-based organizations in developing and testing technologies to prevent and mitigate the harmful effects of algal blooms on coastal and freshwater ecosystems.

Science and Technology
Public and State controlled institutions of higher education
Field Initiated Projects Program (Development) - 0204
$250,000
U.S. Department of Health and Human Services (Administration for Community Living)
Federal

Application Deadline

Not specified

Date Added

Sep 8, 2025

This funding opportunity provides financial support for innovative projects that develop practical solutions to improve the lives of individuals with disabilities, particularly those with the greatest support needs.

Science and Technology
State governments
NIDCD Cooperative Agreement for Clinical Trials in Communication Disorders (U01 - Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jan 7, 2025

This funding opportunity supports clinical trials that develop and test new treatments for communication disorders, such as those affecting hearing, speech, and language, and is open to a wide range of eligible organizations, including universities and nonprofits.

Health
State governments
Forecast to Publish a Notice of Funding Opportunity for Paul Calabresi Career Development Award in Clinical Oncology (K12 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jul 2, 2025

This funding opportunity supports institutions in training clinician-scientists to advance cancer research through structured mentorship and research programs.

Health
State governments
Notice of Intent to Publish a Funding Opportunity Announcement for NIDA REI: Reaching Equity at the Intersection of HIV and Substance Use: Novel Approaches to Address HIV Related Health Disparities in Underserved Racial and/or Ethnic Populations (R01)
$2,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 26, 2024

This funding opportunity is designed to support innovative research projects that address health disparities related to HIV and substance use in underserved racial and ethnic communities.

Health
Small businesses
National K12 Program for the Career Development of Clinician-Scientists in Diabetes Research (Diabetes-DOCS)
$3,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jul 1, 2026

Date Added

Dec 30, 2025

This funding opportunity is designed to support physicians in developing independent research careers focused on diabetes, particularly Type 1 Diabetes, while addressing the shortage of pediatric endocrinologists and promoting diverse participation in diabetes research across the United States.

Health
State governments
New Generation of Glucose Control Technologies Incorporating AI/ML Tools/Strategies
$3,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 19, 2025

This funding opportunity supports researchers and organizations developing innovative AI and machine learning technologies to improve glucose control for individuals with Type 1 Diabetes.

Health
For profit organizations other than small businesses
NIAID Clinical Trial Implementation Cooperative Agreement
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 28, 2025

This funding opportunity supports a wide range of organizations in conducting high-risk clinical trials focused on allergy and infectious diseases, providing resources for research activities, participant recruitment, and regulatory compliance.

Health
State governments
Community Engagement Evaluation and Data Coordination (CEED) Hub to Advance Data and Practice Transformation for Optimizing Oral Health For All Across the Lifespan (U01, Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

May 28, 2025

This funding opportunity supports organizations in developing a central hub for evaluating and coordinating community-driven oral health initiatives aimed at reducing disparities and improving health outcomes across all age groups.

Health
State governments
Industrial Energy Storage Systems Prize
$400,000
U.S. Department of Energy (DOE)
Federal

Application Deadline

Not specified

Date Added

Oct 22, 2024

This competition provides $4.8 million in funding to individuals and organizations developing innovative energy storage solutions that improve energy efficiency and reduce carbon emissions in industrial facilities.

Energy
For profit organizations other than small businesses
Science of Organizations
$3,270,000
National Science Foundation
Federal

Application Deadline

Not specified

Date Added

Feb 18, 2024

This program provides funding for researchers to explore and enhance the understanding of organizations across various sectors, focusing on theoretical contributions and rigorous methodologies.

Science and Technology
Public and State controlled institutions of higher education
Mechanistic Exploration of Therapeutic Targets and Treatable Traits to Improve CNS Outcomes in People with HIV
$3,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 10, 2025

This funding opportunity supports innovative research to identify and develop treatments for central nervous system complications in people living with HIV, inviting a diverse range of applicants including governments, nonprofits, and educational institutions.

Health
State governments
Advancing Research on Empirically-Supported Interventions for Older Adults Living with Serious Mental Illness (SMI)
$3,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 18, 2025

This funding opportunity supports research to improve mental health care for older adults with serious mental illness by developing and evaluating effective interventions across various healthcare settings.

Health
Nonprofits
Clinical Studies of Orphan Products Addressing Unmet Needs of Rare Diseases (R01 Clinical Trials Required)
Contact for amount
U.S. Department of Health & Human Services (Food and Drug Administration)
Federal

Application Deadline

Not specified

Date Added

Jul 12, 2025

This funding opportunity supports clinical research aimed at developing new treatments for rare diseases, targeting organizations and institutions that can conduct trials to demonstrate the safety and efficacy of orphan products.

Health
Public and State controlled institutions of higher education
Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed)
$250,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 10, 2024

This funding opportunity supports researchers conducting observational studies to improve understanding and treatment of musculoskeletal, rheumatic, and skin diseases, ultimately informing future clinical trials.

Health
State governments
NIH Research Project Grant (Parent R01 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 19, 2024

This funding opportunity supports research projects that involve clinical trials to improve health outcomes, targeting a wide range of eligible applicants including universities, nonprofits, and international organizations.

Education
State governments
Spinal Cord Injury (SCI) Model Systems National Data and Statistical Center
$800,000
U.S. Department of Health and Human Services (Administration for Community Living)
Federal

Application Deadline

Not specified

Date Added

Sep 8, 2025

This funding opportunity provides financial support to a wide range of organizations for establishing a national data center focused on improving rehabilitation and independent living outcomes for individuals with spinal cord injuries through rigorous data collection and research collaboration.

Science and Technology
State governments
Mood and Psychosis Symptoms during the Menopause Transition (R01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 25, 2024

This grant provides funding for researchers to study the neurobiological and behavioral mechanisms of mood and psychosis symptoms in women undergoing menopause, with the goal of developing new interventions and improving mental health outcomes.

Health
State governments