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Grants for Small businesses - Federal

Explore 1,527 grant opportunities

Translational Neural Devices (R61/R33 - Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 28, 2027

Date Added

Oct 31, 2024

This funding opportunity supports the development and clinical testing of innovative neural devices designed to treat nervous system or neuromuscular disorders, encouraging diverse participation and collaboration among various institutions and organizations.

Health
State governments
Leveraging Network Infrastructure to Conduct Innovative Research for Women, Children, Pregnant and Lactating Women, and Persons with Disabilities (UG3/UH3 - Clinical Trial Optional)
$6,250,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 15, 2027

Date Added

Dec 17, 2024

This funding opportunity provides financial support for innovative research projects focused on improving health outcomes for women, children, pregnant and lactating women, and individuals with disabilities through multisite clinical trials and observational studies.

Health
Public and State controlled institutions of higher education
Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R21 Clinical Trials Not Allowed) - PAR-25-096
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 7, 2026

Date Added

Nov 19, 2024

This grant provides funding for researchers to analyze and integrate existing cancer-related data to improve understanding of cancer risk, prevention, and outcomes, particularly in underrepresented populations.

Education
State governments
Subsistence Network (SUBNET) Broad Agency Announcement (BAA-0004-21)
Contact for amount
Defense Logistics Agency (DLA), Department of Defense (DoD)
Federal

Application Deadline

Jan 1, 2027

Date Added

Mar 20, 2025

This funding opportunity supports research and development in the military subsistence supply chain, inviting industry, educational institutions, and small businesses to innovate in food production, safety, and logistics for military personnel.

Food and Nutrition
For profit organizations other than small businesses
High-efficiency Nitrogen Oxidation (HNO3)
Contact for amount
U.S. Department of Defense (DARPA - Defense Sciences Office)
Federal

Application Deadline

Feb 5, 2026

Date Added

Dec 2, 2025

This funding opportunity is designed for researchers and organizations developing innovative methods to produce nitric acid more efficiently and sustainably, reducing reliance on traditional ammonia-based processes.

Science and Technology
State governments
Environmental Engineering
$10,000,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Jun 2, 2025

This funding opportunity supports innovative research projects that aim to reduce pollution and improve environmental and human health through interdisciplinary approaches in environmental engineering.

Science and Technology
Nonprofits
Dynamics, Control and Systems Diagnostics
Contact for amount
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Mar 30, 2022

This funding opportunity supports researchers in developing innovative methods for modeling, analyzing, diagnosing, and controlling dynamic systems across various applications.

Science and Technology
Public and State controlled institutions of higher education
Open Topics Broad Agency Announcement
$10,000,000
Strategic Environmental Research and Development Program
Federal

Application Deadline

Aug 21, 2026

Date Added

Aug 26, 2025

This funding opportunity supports private sector organizations, including small businesses and nonprofits, in developing innovative environmental technologies and methods to enhance military readiness and resilience for the U.S. Department of Defense.

Environment
For profit organizations other than small businesses
Clean Water State Revolving Fund (CWSRF)
Contact for amount
U.S. Environmental Protection Agency
Federal
Rolling

Application Deadline

Not specified

Date Added

Oct 9, 2025

This program provides low-interest loans to states and eligible entities for various water quality improvement projects, including wastewater treatment and stormwater management, to enhance public health and environmental sustainability.

Environment
Nonprofits
Innovative Solutions Opening
Contact for amount
US Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 5, 2029

Date Added

Jun 19, 2025

This funding opportunity is designed for innovators and organizations developing transformative healthcare technologies that enhance access and affordability, particularly in underserved areas.

Health
For profit organizations other than small businesses
NARMS Cooperative Agreement Program to Strengthen Antibiotic Resistance Surveillance in Retail Food Specimens
$200,000
U.S. Department of Health & Human Services (Food and Drug Administration)
Federal

Application Deadline

Apr 1, 2027

Date Added

Jul 12, 2025

This funding opportunity provides financial support to educational institutions, nonprofits, and government entities to enhance surveillance of antibiotic resistance in bacteria found in retail food, particularly raw meats and seafood.

Health
Public and State controlled institutions of higher education
Advanced Laboratories for Accelerating the Reach and Impact of Treatments for Youth and Adults with Mental Illness (ALACRITY) Research Centers (P50 Clinical Trial Optional)
$1,500,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

May 18, 2026

Date Added

Jun 20, 2023

This funding opportunity provides financial support for research centers focused on improving mental health treatments and services for youth and adults in the U.S. through innovative approaches and collaboration among diverse stakeholders.

Health
State governments
Summer Research Education Experience Program (R25 Clinical Trial Not Allowed)
$125,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 17, 2027

Date Added

Nov 1, 2024

This grant provides financial support for summer research programs designed to engage high school and undergraduate students, as well as science teachers, in hands-on biomedical and behavioral research experiences to inspire future careers in these fields.

Education
State governments
Unmanned Robotic Rafting Bays for Military Use
$250,000
U.S. Department of Defense (DoD)
Federal
Rolling

Application Deadline

Not specified

Date Added

Feb 27, 2025

This funding opportunity is designed for small businesses and innovators to develop autonomous robotic systems for military river crossings, enhancing safety and efficiency in contested environments.

Science and Technology
Small businesses
OVC FY25 Specialized Human Trafficking Assistance: Supporting Survivor Engagement in Anti-Trafficking Programming
$1,200,000
U.S. Department of Justice (Office for Victims of Crime)
Federal

Application Deadline

Feb 24, 2026

Date Added

Dec 31, 2025

This funding opportunity provides financial support to organizations that aim to enhance survivor involvement in anti-human trafficking programs by developing training, resources, and collaborative networks.

Law Justice and Legal Services
Nonprofits
Substance Use/Substance Use Disorder Dissertation Research Award (R36 Clinical Trials Not Allowed)
$50,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 16, 2026

Date Added

Jan 3, 2025

This funding opportunity supports doctoral candidates conducting research on substance use and addiction, focusing on innovative approaches to prevention, treatment, and health disparities among underserved populations.

Education
State governments
Rfa-Cd-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Nov 26, 2025

This funding opportunity provides financial support for a wide range of public health initiatives focused on preventing and controlling injuries and violence through community and state-level interventions, targeting a diverse group of applicants including governments, universities, and nonprofits.

Health
State governments
Social disconnection and Suicide Risk in Late Life (R01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 5, 2026

Date Added

Nov 19, 2024

This funding opportunity supports research on how social isolation and loneliness affect suicide risk in older adults, aiming to identify protective factors and inform interventions for vulnerable populations.

Health
State governments
New World Screwworm Grand Challenge
$5,000,000
U.S. Department of Agriculture (Animal and Plant Health Inspection Service)
Federal

Application Deadline

Feb 23, 2026

Date Added

Jan 22, 2026

This funding opportunity provides up to $100 million to a variety of organizations for innovative projects aimed at detecting, controlling, and eradicating the invasive New World Screwworm to protect U.S. livestock and agriculture.

Animal Welfare
State governments
Clinical Validation of a Candidate Biomarker for Neurological or Neuromuscular Disorders (U01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 22, 2026

Date Added

Oct 3, 2024

This funding opportunity supports U.S.-based institutions and organizations in validating candidate biomarkers for neurological and neuromuscular disorders to improve clinical decision-making and therapeutic development.

Health
State governments