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Grants for Small businesses - Federal

Explore 1,527 grant opportunities

Rfa-Ce-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Nov 26, 2025

This funding opportunity provides financial support for a wide range of organizations, including state governments, universities, and nonprofits, to conduct research and initiatives focused on preventing injuries and improving community health.

Health
State governments
Needipedia Broad Agency Announcement
Contact for amount
Defense Intelligence Agency (DIA)
Federal
Rolling

Application Deadline

Dec 26, 2028

Date Added

Mar 20, 2025

This funding initiative invites businesses, academic institutions, and nonprofits to propose innovative solutions that address intelligence and defense needs for potential future support from the Defense Intelligence Agency.

Science and Technology
For profit organizations other than small businesses
ERDC Broad Agency Announcement
$999,999,999
U.S. Department of Defense (Engineer Research and Development Center)
Federal

Application Deadline

Jan 1, 2027

Date Added

Jan 5, 2026

This funding opportunity supports innovative research and development projects in various scientific and engineering fields, particularly those that align with military and civil missions, and encourages collaboration among universities, non-profits, and small businesses, including participation from minority institutions.

Science and Technology
Public and State controlled institutions of higher education
Pay-for-Performance Incentive Payments Program
$40,000,000
U.S. Department of Labor (Employment and Training Administration)
Federal

Application Deadline

Not specified

Date Added

Jan 7, 2026

This funding initiative provides financial incentives to organizations that manage apprenticeship programs in key industries, aiming to significantly increase the number of active apprentices across the United States.

Employment Labor and Training
State governments
Alcohol and Other Substance Use Research Education Programs for Health Professionals (R25 Clinical Trial Not Allowed)
$250,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

May 25, 2026

Date Added

Aug 1, 2023

This funding opportunity supports innovative educational programs that equip health professionals with the latest research and evidence-based practices related to alcohol and substance use disorders, enhancing patient care and addressing treatment disparities.

Health
State governments
Perception, Action Cognition
$715,000
National Science Foundation
Federal

Application Deadline

Feb 2, 2026

Date Added

Apr 17, 2025

This funding opportunity supports researchers investigating human perception, action, and cognition, encouraging innovative studies that have practical societal benefits.

Science and Technology
Individuals
Trailblazer Award for New and Early Stage Investigators (R21 Clinical Trial Optional)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 16, 2026

Date Added

Jan 9, 2025

This funding opportunity supports innovative research projects by new and early-stage investigators in the fields of engineering, physical sciences, and biomedical sciences, encouraging exploration and development of transformative technologies without the need for preliminary data.

Health
State governments
Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed)
$50,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 16, 2027

Date Added

Oct 31, 2024

This funding opportunity provides financial support for small-scale research projects that aim to improve the adoption and sustainability of evidence-based health practices, particularly in underserved communities, by addressing barriers and engaging diverse stakeholders.

Education
State governments
NINDS Research Education Opportunities (R25 Clinical Trial Not Allowed)
$250,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jul 14, 2026

Date Added

May 14, 2024

This funding opportunity supports national neuroscience education programs that provide hands-on research experiences and training for graduate students, postdoctoral researchers, and junior faculty to enhance the biomedical research workforce.

Education
Public and State controlled institutions of higher education
Strengthening Ghana Health Service laboratory systems activities under the Presidents Emergency Plan for AIDS Relief (PEPFAR)
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control-GHC)
Federal

Application Deadline

Feb 17, 2026

Date Added

Oct 17, 2025

This funding opportunity provides financial support to organizations working to strengthen laboratory systems in Ghana, enhancing HIV testing, treatment monitoring, and data management to improve public health outcomes.

Health
State governments
NIDA Research Education Program for Clinical Researchers and Clinicians (R25 Clinical Trial Not Allowed)
$350,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 12, 2027

Date Added

Nov 19, 2024

This funding opportunity provides financial support for educational programs aimed at training clinicians and clinical researchers in substance use and substance use disorder research to enhance their skills and research experiences.

Education
State governments
Revision Applications for Validation of Biomarker Assays Developed Through NIH-Supported Research Grants (R01 Clinical Trial Not Allowed)
$150,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 14, 2026

Date Added

Oct 11, 2024

This funding opportunity is designed for researchers with active NCI R01 grants to validate and enhance existing cancer biomarker assays, facilitating their clinical use and improving cancer detection and treatment strategies.

Health
Public and State controlled institutions of higher education
A Science of Science Approach to Analyzing and Innovating the Biomedical Research Enterprise
$250,000
National Science Foundation
Federal

Application Deadline

Feb 9, 2026

Date Added

Sep 25, 2024

This funding opportunity provides financial support for researchers and institutions to analyze and improve the biomedical research system, promoting innovation and a diverse scientific workforce.

Science and Technology
Public and State controlled institutions of higher education
Resource-Related Research Projects for Development of Models and Related Materials for Studying Human Health and Diseases (R24 Clinical Trials Not Allowed)
$20,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

May 27, 2026

Date Added

Jun 10, 2025

This funding opportunity supports U.S.-based researchers and institutions in developing innovative experimental models and resources that advance the understanding of human health and diseases across multiple biomedical disciplines.

Health
Public and State controlled institutions of higher education
Mitochondrial-associated Mechanisms of Neuropathological and Immunodeficient Aging in the Context of HIV and SUD (R21 Clinical Trials Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 10, 2026

Date Added

Oct 1, 2024

This funding opportunity supports early-stage research on how mitochondrial dysfunction affects aging and immune health in individuals with HIV who use addictive substances, aiming to uncover potential therapeutic strategies.

Education
State governments
Coupling, Energetics, and Dynamics of Atmospheric Regions
$750,000
National Science Foundation
Federal

Application Deadline

Mar 4, 2026

Date Added

Mar 21, 2025

This grant provides funding for research on the upper atmosphere, encouraging innovative studies that integrate various scientific disciplines and promote participation from diverse institutions and early career scientists.

Science and Technology
Public and State controlled institutions of higher education
Cutting-Edge Basic Research Awards (CEBRA) (R21 Clinical Trial Optional)
$150,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 10, 2026

Date Added

Dec 31, 2024

This funding opportunity supports innovative research projects aimed at understanding and addressing substance use disorders, encouraging both established and new researchers to explore groundbreaking ideas and methods in addiction science.

Education
State governments
ROSES 2025: B.4 Space Weather Science Application Research-to-Operations-to-Research
$1,000,000
National Aeronautics and Space Administration (NASA Headquarters)
Federal

Application Deadline

Apr 10, 2026

Date Added

Jul 15, 2025

This funding opportunity supports U.S.-based researchers and organizations in developing innovative space weather forecasting tools and applications that meet the needs of operational users like NOAA and the Department of Defense.

Science and Technology
For profit organizations other than small businesses
Research Interests of the Air Force Office of Scientific Research
$10,000,000
U.S. Department of Defense (Air Force Office of Scientific Research)
Federal
Rolling

Application Deadline

Not specified

Date Added

May 30, 2025

This funding opportunity supports fundamental scientific and engineering research that aligns with the needs of the U.S. Air Force and Space Force, targeting academic institutions, nonprofits, and businesses to foster innovations with potential military and industrial applications.

Science and Technology
Public and State controlled institutions of higher education
BJS FY25 Survey of Public Defenders (SPD)
$1,000,000
U.S. Department of Justice (Bureau of Justice Statistics)
Federal

Application Deadline

Mar 2, 2026

Date Added

Jan 22, 2026

This funding opportunity provides financial support to organizations that will collect and analyze national data on public defenders in the U.S., focusing on their demographics, workloads, and resources to improve indigent defense services.

Information and Statistics
Public and State controlled institutions of higher education