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Grants for Small businesses - Federal

Explore 1,527 grant opportunities

US Army Combat Capabilities Development Command Broad Agency Announcement
Contact for amount
U.S. Department of Defense (ACC APG - Natick)
Federal

Application Deadline

Feb 27, 2030

Date Added

Jul 15, 2025

This funding opportunity supports innovative research and technological solutions for next-generation soldier technologies, targeting universities, nonprofit research institutions, and commercial firms, excluding government organizations.

Science and Technology
Public and State controlled institutions of higher education
Forecast to Publish a Funding Opportunity Announcement for Copy of Integrative Neuroscience Initiative on Alcoholism (INIA) Consortia Administrative Resource Core (U24) (Clinical Trial Optional)
$1,200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

May 1, 2026

Date Added

May 7, 2025

This funding opportunity supports collaborative research projects focused on understanding the brain and body mechanisms that contribute to excessive alcohol consumption and Alcohol Use Disorder, encouraging innovative approaches and partnerships among researchers.

Health
State governments
Injury Prevention and Control Research and State and Community Based Programs - RFA-IP-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Oct 20, 2023

This funding opportunity provides financial support for a variety of organizations, including states, universities, and nonprofits, to develop and implement research and community programs focused on preventing and controlling injuries.

Health
State governments
Forecast for NIH Blueprint and BRAIN Initiative ACTION Potential Program (F99/K00 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 20, 2026

Date Added

May 28, 2025

This funding opportunity supports neuroscience graduate students in completing their doctoral studies and transitioning to postdoctoral research positions, fostering their development into independent investigators in the field.

Health
State governments
Complement-ARIE NAMs Reduction to Practice Challenge
$1,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 1, 2026

Date Added

Dec 24, 2025

This grant provides financial support to teams developing innovative, non-animal research methods that improve the relevance and accuracy of biomedical and toxicity testing.

Science and Technology
Individuals
Mechanism for Time-Sensitive Substance Use Research (R21 Clinical Trial Optional)
$275,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 9, 2027

Date Added

Sep 27, 2024

This funding opportunity provides financial support for research projects that urgently address emerging substance use issues, such as spikes in drug overdoses or changes in drug policies, with a focus on collaboration between researchers and public partners.

Education
State governments
Science of Science: Discovery, Communication and Impact
Contact for amount
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

May 9, 2025

This grant provides funding for researchers to explore and improve the processes of scientific discovery, communication, and its impact on society, with a focus on innovative and transformative approaches.

Science and Technology
Nonprofits
Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Development and Validation of Model Systems to Facilitate Neurotherapeutic Discovery (R61/R33 Clinical Trial Not Allowed)
$750,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 20, 2027

Date Added

Oct 23, 2024

This funding opportunity provides financial support for research institutions and organizations to develop and validate innovative model systems that can improve the discovery of new treatments for neurological and neuromuscular disorders.

Health
State governments
ROSES25: C.12 Foundational Artificial Intelligence for the Moon and Mars
Contact for amount
National Aeronautics and Space Administration (NASA Headquarters)
Federal

Application Deadline

Apr 28, 2026

Date Added

Jan 14, 2026

This grant provides funding for researchers and institutions in the U.S. to develop advanced artificial intelligence technologies that will support NASA's exploration missions to the Moon and Mars.

Science and Technology
Individuals
Fiscal Year 2026 University Reactor Sharing and Outreach
$200,000
U.S. Department of Energy (Idaho Field Office)
Federal

Application Deadline

Feb 27, 2026

Date Added

Jan 7, 2026

This funding opportunity provides financial support to U.S. universities with operational nuclear research reactors to promote collaboration, education, and public engagement in nuclear science and engineering.

Education
Public and State controlled institutions of higher education
CHIPS Research and Development Office (CRDO) Broad Agency Announcement (BAA)
Contact for amount
U.S. Department of Commerce (National Institute of Standards and Technology)
Federal

Application Deadline

Sep 30, 2029

Date Added

Sep 25, 2025

This funding opportunity supports U.S. organizations in advancing research and commercialization of microelectronics and related technologies to strengthen domestic innovation and supply chains.

Science and Technology
For profit organizations other than small businesses
ROSES 2025: C.2 Solar System Science
Contact for amount
National Aeronautics and Space Administration (NASA Headquarters)
Federal

Application Deadline

Aug 1, 2026

Date Added

Jul 12, 2025

This grant provides funding for researchers at U.S.-based institutions to conduct innovative studies that enhance our understanding of planetary science and the solar system.

Science and Technology
Public and State controlled institutions of higher education
BRAIN Initiative: Production and distribution facilities for brain cell type-specific access reagents (U24 Clinical Trial Not Allowed)
$2,400,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jul 1, 2026

Date Added

Feb 21, 2024

This funding opportunity supports the establishment of facilities that will produce and distribute specialized brain cell access tools for neuroscience research, enabling scientists to better study and manipulate specific brain cell types.

Health
Public and State controlled institutions of higher education
BROAD AGENCY ANNOUNCEMENT (BAA) for Extramural Biomedical and Human Performance Research and Development Department of Defense
$10,000,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Jul 31, 2028

Date Added

Jul 27, 2023

This funding opportunity supports research projects that improve medical and human performance capabilities for military personnel, focusing on innovative solutions for Special Operations Forces in challenging environments.

Health
Nonprofits
Fiscal Year 2026 Consolidated Innovative Nuclear Research
$3,100,000
U.S. Department of Energy (Idaho Field Office)
Federal

Application Deadline

Jun 9, 2026

Date Added

Dec 16, 2025

This funding opportunity provides financial support for U.S. universities, colleges, and eligible research entities to conduct innovative nuclear energy research and development projects that address key challenges in the nuclear sector.

Energy
Public and State controlled institutions of higher education
Advancing Nutrition-related Research Across the Lifespan
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Apr 27, 2026

Date Added

May 29, 2025

This funding opportunity supports a wide range of organizations in conducting research to improve nutrition-related health outcomes and reduce health disparities across all life stages by addressing social factors that influence nutrition.

Health
State governments
Advanced Cyber Effects for Strategic Operations
$99,980,000
U.S. Department of Defense
Federal

Application Deadline

Jul 10, 2030

Date Added

Sep 29, 2025

This grant provides funding for innovative research and development of cyber operations prototypes to enhance the U.S. Department of Defense's capabilities in the cyber domain, targeting a wide range of eligible applicants including universities, businesses, and research organizations.

Science and Technology
For profit organizations other than small businesses
BJS FY25 National Victimization Statistical Support Program (NVSSP)
$2,000,000
U.S. Department of Justice (Bureau of Justice Statistics)
Federal

Application Deadline

Feb 10, 2026

Date Added

Jan 16, 2026

This funding opportunity provides financial support for research and statistical analysis related to crime and victimization, primarily aimed at enhancing the National Crime Victimization Survey and its methodologies.

Information and Statistics
Independent school districts
Defense Sciences Office (DSO) Office-wide BAA
Contact for amount
U.S. Department of Defense (DARPA - Defense Sciences Office)
Federal

Application Deadline

Jun 2, 2026

Date Added

Jun 4, 2025

This grant provides funding for innovative research proposals that advance scientific and technological breakthroughs to enhance national security, targeting a wide range of applicants including private institutions, nonprofits, and small businesses.

Science and Technology
For profit organizations other than small businesses
Metal Casting BAA0001-21
Contact for amount
Defense Logistics Agency (DLA), Department of Defense (DoD)
Federal

Application Deadline

Jun 30, 2026

Date Added

Mar 20, 2025

This funding opportunity supports research and development in metal casting technologies to enhance military applications and meet national defense needs.

Science and Technology
For profit organizations other than small businesses