Federal for Small businesses Grants

This funding opportunity supports small businesses in the U.S. to develop innovative solutions for diagnosing and treating health issues related to non-disordered drug use, such as complications from opioid and stimulant use.

The "Single Source for the Continuation of the Human Pancreas Analysis Program (HPAP) for Type 1 Diabetes (HPAP-T1D)" grant is intended to fund the University of Pennsylvania's ongoing research into understanding and combating Type 1 Diabetes, by studying human pancreatic tissues and immune cells, and sharing their findings through an open-access database.

This Funding Opportunity Announcement (FOA) encourages Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that propose to further the development of Technology-Enhanced Training Products for the health and safety training of hazardous materials (HAZMAT) workers; waste treatment personnel; skilled support personnel associated with an emergency/disaster; emergency responders in biological hazard response, infectious disease response, and medical waste cleanup; emergency responders in disasters; and worker resiliency training. Technology-enhanced training products as defined by the Worker Training Program (WTP) include, but are not limited to, supporting training through various venues such as online training, mobile device training, virtual reality, and serious gaming. These advanced technologies complement all phases of training that can enhance, supplement, improve, and provide health and safety training for hazardous materials workers. These products must complement the goals and objectives of the WTP. The major objective of the NIEHS WTP is to prevent work related harm by training workers in how best to protect themselves and their communities from exposure to hazardous materials. The financial support for this initiative comes directly from NIEHS Worker Education and Training Branch SBIR funds.

This funding opportunity supports new entrepreneurs in small businesses by providing resources for their career development and research efforts, particularly in health-related technologies.

This funding opportunity supports new entrepreneurs in small businesses by providing resources for their career development and research efforts, helping them grow their skills while advancing innovative health-related technologies.

This funding opportunity supports new entrepreneurs in small businesses by providing resources for their career development and research efforts, helping them to grow their skills in technology development and healthcare delivery.

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits Small Business Innovation Research (SBIR) applications from small business concerns (SBCs) that seek additional funding to support the next stage of development for cancer-relevant projects that were previously funded under SBIR or STTR Phase II awards from any Federal agency. The purpose of this NOFO is to facilitate the transition of SBIR or STTR Phase II projects to the commercialization stage. This NOFO is expected to promote partnerships between Federally-funded SBIR or STTR Phase II awardees and third-party investors and/or strategic partners to facilitate and accelerate the capital-intensive steps that are required to commercialize new products and services. Applicants must submit a Commercialization Plan, which should include details on any independent third-party investor funding that has already been secured or is anticipated during the Phase IIB Bridge Award project period. It is expected that the level of this independent third-party funding will be equal to or greater than the NCI funds being requested throughout the Phase IIB Bridge Award project period. Proposed projects may address preclinical and/or clinical stages of technology development. Clinical trials may be proposed as appropriate but are not required.

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to support early-career academic scientists interested in transitioning to entrepreneurship while also supporting the transfer of technology from academic laboratories into small businesses. Both small businesses and universities are drivers of technological innovation in the United States (U.S.), often working together to advance innovative ideas into products that can benefit the U.S. population. While most NIH funding supports basic research in university laboratories, the NIH also supports innovative technology development in U.S. small businesses through its SBIR and STTR programs. As technologies transition from academic discovery to small businesses, two common challenges arise, identifying the right team with the right expertise to take the product into a small business, and funding for early-stage technology development. This NOFO seeks to address both challenges simultaneously by having two equally important goals: entrepreneurial mentoring support, and product development support.

To obtain a copy of the Funding Opportunity Announcement (FOA) please go to the ARPA-E website at https://arpa-e-foa.energy.gov. To apply to this FOA, Applicants must register with and submit application materials through ARPA-E eXCHANGE (https://arpa-e-foa.energy.gov/Registration.aspx). For detailed guidance on using ARPA-E eXCHANGE, please refer to the ARPA-E eXCHANGE User Guide (https://arpa-e-foa.energy.gov/Manuals.aspx). ARPA-E will not review or consider concept papers submitted through other means. For problems with ARPA-E eXCHANGE, email [email protected] (with FOA name and number in the subject line). Questions about this FOA? Check the Frequently Asked Questions available at http://arpa-e.energy.gov/faq. For questions that have not already been answered, email [email protected]. Agency Overview: The Advanced Research Projects Agency Energy (ARPA-E), an organization within the Department of Energy (DOE), is chartered by Congress in the America COMPETES Act of 2007 (P.L. 110-69), as amended by the America COMPETES Reauthorization Act of 2010 (P.L. 111-358), as further amended by the Energy Act of 2020 (P.L. 116-260) to: (A) to enhance the economic and energy security of the United States through the development of energy technologies that (i) reduce imports of energy from foreign sources; (ii) reduce energy-related emissions, including greenhouse gases; (iii) improve the energy efficiency of all economic sectors; (iv) provide transformative solutions to improve the management, clean-up, and disposal of radioactive waste and spent nuclear fuel; and (v) improve the resilience, reliability, and security of infrastructure to produce, deliver, and store energy; and (B) to ensure that the United States maintains a technological lead in developing and deploying advanced energy technologies. ARPA-E issues this Funding Opportunity Announcement (FOA) under its authorizing statute codified at 42 U.S.C. 16538. The FOA and any awards made under this FOA are subject to 2 C.F.R. Part 200 as supplemented by 2 C.F.R. Part 910. ARPA-E funds research on and the development of transformative science and technology solutions to address the energy and environmental missions of the Department. The agency focuses on technologies that can be meaningfully advanced with a modest investment over a defined period of time in order to catalyze the translation from scientific discovery to early-stage technology. For the latest news and information about ARPA-E, its programs and the research projects currently supported, see: http://arpa-e.energy.gov/. ARPA-E funds transformational research. Existing energy technologies generally progress on established learning curves where refinements to a technology and the economies of scale that accrue as manufacturing and distribution develop drive down the cost/performance metric in a gradual fashion. This continual improvement of a technology is important to its increased commercial deployment and is appropriately the focus of the private sector or the applied technology offices within DOE. By contrast, ARPA-E supports transformative research that has the potential to create fundamentally new learning curves. ARPA-E technology projects typically start with cost/performance estimates well above the level of an incumbent technology. Given the high risk inherent in these projects, many will fail to progress, but some may succeed in generating a new learning curve with a projected cost/performance metric that is significantly lower than that of the incumbent technology. ARPA-E funds technology with the potential to be disruptive in the marketplace. The mere creation of a new learning curve does not ensure market penetration. Rather, the ultimate value of a technology is determined by the marketplace, and impactful technologies ultimately become disruptive that is, they are widely adopted and displace existing technologies from the marketplace or create entirely new markets. ARPA-E understands that definitive proof of market disruption takes time, particularly for energy technologies. Therefore, ARPA-E funds the development of technologies that, if technically successful, have clear disruptive potential, e.g., by demonstrating capability for manufacturing at competitive cost and deployment at scale. ARPA-E funds applied research and development. The Office of Management and Budget defines applied research as an original investigation undertaken in order to acquire new knowledgedirected primarily towards a specific practical aim or objective and defines experimental development as creative and systematic work, drawing on knowledge gained from research and practical experience, which is directed at producing new products or processes or improving existing products or processes. (http://science.energy.gov/). Office of Science national scientific user facilities (http://science.energy.gov/user-facilities/) are open to all researchers, including ARPA-E Applicants and awardees. These facilities provide advanced tools of modern science including accelerators, colliders, supercomputers, light sources and neutron sources, as well as facilities for studying the nanoworld, the environment, and the atmosphere. Projects focused on early-stage R for the improvement of technology along defined roadmaps may be more appropriate for support through the DOE applied energy offices including: the Office of Energy Efficiency and Renewable Energy (http://www.eere.energy.gov/), the Office of Fossil Energy (http://fossil.energy.gov/), the Office of Nuclear Energy (http://www.energy.gov/ne/office-nuclear-energy), and the Office of Electricity Delivery and Energy Reliability (http://energy.gov/oe/office-electricity-delivery-and-energy-reliability). Applicants interested in receiving financial assistance for basic research (defined by the Office of Management and Budget as experimental or theoretical work undertaken primarily to acquire new knowledge of the underlying foundations of phenomena and observable facts) should contact the DOEs Office of Science (http://science.energy.gov/). Office of Science national scientific user facilities (http://science.energy.gov/user-facilities/) are open to all researchers, including ARPA-E Applicants and awardees. These facilities provide advanced tools of modern science including accelerators, colliders, supercomputers, light sources and neutron sources, as well as facilities for studying the nanoworld, the environment, and the atmosphere. Projects focused on early-stage R for the improvement of technology along defined roadmaps may be more appropriate for support through the DOE applied energy offices including: the Office of Energy Efficiency and Renewable Energy (http://www.eere.energy.gov/), the Office of Fossil Energy (http://fossil.energy.gov/), the Office of Nuclear Energy (http://www.energy.gov/ne/office-nuclear-energy), and the Office of Electricity Delivery and Energy Reliability (http://energy.gov/oe/office-electricity-delivery-and-energy-reliability). Program Description: According to the U.S. Environmental Protection Agency (EPA), a circular economy refers to an economy that uses a systems-focused approach and involves industrial processes and economic activities that are restorative or regenerative by design, enables resources used in such processes and activities to maintain their highest value for as long as possible, and aims for the elimination of waste through the superior design of materials, products, and systems. Further, a circular economy reduces material use, redesigns materials, products, and services to be less resource intensive, and recaptures waste as a resource to manufacture new materials and products. Successfully achieving a circular economy requires implementing the above principles to the supply chains of numerous products. Specifically, creating a circular EV battery supply chain focuses on optimizing the full vehicle life cycle. Thus, the emphasis must shift from production and sales within an ownership model to a model focusing on customers mobility needs and access in the form of leasing, as it exists today, vehicle-on-demand (e.g., Zipcar), and mobility-on-demand (e.g., robotaxis). These different business models may coexist but will require increasing collaboration and transparency among different actors, while costs and revenues will be distributed across the supply chain. A circular supply chain offers new revenue streams and business opportunities by providing services to maximize EVs lifetime performance through: Enhancing regular predictive maintenance; Repairing and remanufacturing of battery modules and packs; Improving the reuse and recovery of EOL parts and materials; and Minimizing carbon footprint and maximizing resource efficiency. A circular supply chain also offers opportunities to reduce production and operating costs by: Improving the quality and stability of critical minerals supply chains through cell regeneration, reuse, and recycling; Facilitating rework, reuse, repair, and remanufacture of batteries through modular designs, reversible manufacturing materials and methods; and Reducing asset costs per unit amount of energy delivered owing to the retention of the embedded manufacturing value of batteries, their prolonged lifetime, and the extended use of EVs. The overarching goal of the CIRCULAR program is to successfully translate the above definition of a circular economy to the domestic EV battery supply chain by supporting the development of innovative solutions that can overcome both the technological and economic barriers to broad commercial adoption. CIRCULAR acknowledges that simultaneous advancements in multiple technological domains may be required to accomplish this ambitious objective. Therefore, the program is intentionally structured into three technology development categories designed to converge towards the creation of a domestic circular supply chain for EV batteries. The CIRCULAR program recognizes that conventional recycling is not the only, nor primary, pathway to closing the supply chain loop. Therefore, the primary objective of this program is to catalyze the creation of a circular EV battery supply chain in North America. The program will support the development and deployment of foundational technologies capable of maintaining materials and products in circulation at their highest level of performance and safety for as long as possible. Achieving this goal will directly impact ARPA-E mission areas as follows: Decrease Energy-Related Imports: The CIRCULAR program aims to reduce the import of critical battery materials, cells, packs, and EVs by establishing new supply chain loops within the U.S. Currently, individual steps in the battery supply chain (mining, material processing, cell component assembly, battery cell manufacturing, and recycling) are concentrated mostly outside of the U.S. Reduce Emissions: The CIRCULAR program aims to decrease the domestic energy burden and carbon footprint of the EV battery supply chain by extending the service life of battery cells and packs and by maintaining manufacturing value to the greatest extent possible through regeneration, repair, reuse, and remanufacture. The program will also reduce emissions associated with battery recycling by minimizing the amount of waste and by recycling only pack components that have reached their EOL. Improve Energy Efficiency: The CIRCULAR program aims to minimize energy and material consumption within the battery supply chain and to exploit opportunities to improve energy efficiency through innovative battery design, material regeneration, and/or manufacturing strategies. To view the FOA in its entirety, please visit https://arpa-e-foa.energy.gov.

The Small Business Innovation Research (SBIR) Program for CHIPS for America CHIPS Metrology seeks applications from eligible applicants to explore the technical merit or feasibility of an innovative idea or technology with the aim of developing a viable product or service that will be introduced to the commercial microelectronics marketplace. This NOFO contains multiple topics on research projects for critically needed measurement services, tools, and instrumentation; innovative manufacturing metrologies; novel assurance and provenance technologies and advanced metrology research and development (R) testbeds to help secure U.S. leadership in the global semiconductor industry.

Introduction to the Program: In 1977, the National Science Foundation (NSF) piloted and subsequently instituted the Small Business Innovation Applied to National Needs program, a precursor to the Small Business Innovation Research (SBIR) program and a first of its kind within the federal government. The goal of this program was to catalyze the innovative capabilities of small firms within the United States by supporting high-risk, potentially high-payoff projects [1].The NSF SBIR/STTR program solicits proposals from small businesses based on groundbreaking scientific discoveries or significant engineering breakthroughs consistent with NSF;apos;s mission to promote the progress of science; to advance the national health, prosperity, and welfare; and to secure the national defense. This NSF program is governed by 15 U.S.C. 638 and the National Science Foundation Act of 1950, as amended (42 U.S.C. 1861 et seq.). The current NSF SBIR/STTR program continues this legacy of supporting the translation of scientific discovery into products and services with commercial potential and/or societal benefit. Unlike fundamental or basic research activities that focus on scientific and engineering discovery itself, the NSF SBIR/STTR program supports the creation of opportunities to move discoveries founded from fundamental science and engineering out of the lab and into the market or other use at scale, through startups and small businesses. The NSF SBIR/STTR program provides non-dilutive research and development funding at the earliest stages of technology development. Synopsis of Program: The NSF SBIR/STTR program supports moving scientific excellence and technological innovation from the lab to the market. By funding startups and small businesses, NSF hopes to build a strong national economy and stimulate the creation of novel products, services, and solutions in the private sector with potential for broad impact; strengthen the role of small business in meeting federal research and development needs; increase the commercial application of federally supported research results; and develop and increase the US workforce, especially by fostering and encouraging participation by socially and economically disadvantaged and women-owned small businesses. The NSF SBIR/STTR program welcomes proposals from many topics and does not have a specific technological focus (please see website at https://seedfund.nsf.gov/portfolio/for a listing of topics and cognizant Program staff). The program is open to proposals focusing on technical and market areas not explicitly noted, and such proposals should be submitted to "Other Topics". [1] R. T. Tibbetts, apos;s three-phase program helps the small-business innovator bootstrap an idea to commercial success," inIEEE Spectrum, vol. 15, no. 10, pp. 86-86, Oct. 1978, doi: 10.1109/MSPEC.1978.6367918.

The National Institute of Standards and Technology (NIST) invites FY 2023 NIST SBIR Phase I awardees to submit Phase II research applications under this Notice of Funding Opportunity (NOFO). Only FY 2023 NIST SBIR Phase I awardees are eligible to submit applications in response to this NOFO for Phase II of their projects. The Small Business Innovation Research (SBIR) program was originally established in 1982 by the Small Business Innovation Development Act (P.L. 97-219), codified at 15 U.S.C. § 638. The SBIR Program was then expanded and extended by the Small Business Research and Development (R&D) Enhancement Act of 1992 (P.L. 102-564), and received subsequent reauthorization and extensions, the most recent of which extends the SBIR program through 2025. (P.L. 117-183). Eleven Federal agencies implement SBIR by setting aside a portion of their extramural research and development budget each year to fund research applications from small science and technology-based firms. The statutory purpose of the SBIR Program is to strengthen the role of innovative small business concerns (SBCs) in Federally-funded research or research and development (R/R&D). Specific program goals are to: (1) stimulate technological innovation; (2) use small businesses to meet Federal R/R&D needs; (3) foster and encourage participation by socially and economically disadvantaged small businesses and by women-owned small businesses in technological innovation; and (4) increase private sector commercialization of innovations derived from Federal R/R&D, thereby increasing competition, productivity, and economic growth.

This notice announces the intention of the Maritime Administration to provide grants to small shipyards. Under the Small Shipyard Grant Program, there is currently $8,750,000 available for grants for capital and related improvements to qualified shipyard facilities that will be effective in fostering efficiency, competitive operations, and quality ship construction, repair, and reconfiguration. Potential applicants are advised that it is expected, based on experience, that the number of applications will far exceed the funds available and that only a small percentage of applicants will be funded. Applications (SF-424 and the Addendum) will be accepted online through Grants.gov by 5 pm on the closing date (May 8, 2024). See full text under Related Documents Tab (FY 2024 SSG NOFO) or the MARAD Web Page (https://www.maritime.dot.gov/grants-finances/small-shipyard-grants) for detailed submission instructions

The Rural Energy for America Program (REAP) provides guaranteed loan financing and grant funding to agricultural producers and rural small businesses in Idaho for renewable energy systems and energy efficiency improvements. Eligible entities include agricultural producers with at least 50% income from agricultural operations and small businesses in rural areas, meeting specific criteria. The program supports a range of projects, including biomass, geothermal, hydropower, wind, and solar energy systems, as well as energy efficiency upgrades. Applications are accepted year-round, with specific deadlines for fiscal years 2023 and 2024.

To obtain a copy of the Funding Opportunity Announcement (FOA) please go to the ARPA-E website at https://arpa-e-foa.energy.gov. To apply to this FOA, Applicants must register with and submit application materials through ARPA-E eXCHANGE (https://arpa-e-foa.energy.gov/Registration.aspx). For detailed guidance on using ARPA-E eXCHANGE, please refer to the ARPA-E eXCHANGE User Guide (https://arpa-e-foa.energy.gov/Manuals.aspx). ARPA-E will not review or consider concept papers submitted through other means. For problems with ARPA-E eXCHANGE, email [email protected] (with FOA name and number in the subject line). Questions about this FOA? Check the Frequently Asked Questions available at http://arpa-e.energy.gov/faq. For questions that have not already been answered, email [email protected]. To read this FOA in its entirety, please go to the ARPA-E website at https://arpa-e-foa.energy.gov. Questions about this FOA? Check the Frequently Asked Questions available at http://arpa-e.energy.gov/faq. For questions that have not already been answered, email [email protected]. The purpose of this modification is to incorporate changes to Funding Opportunity Announcement. Accordingly, this modification, Inserted new Exploratory Topic, Topic L: Plant HYperaccumulators TO MIne Nickel-Enriched Soils (PHYTOMINES). See Table 1. Exploratory Topics, Appendix L, and Total Amounts to be awarded on Cover Page.

This funding opportunity supports small businesses in the U.S. to develop innovative technologies that improve health outcomes and reduce disparities for minority populations.

This funding opportunity supports small businesses in the U.S. to develop innovative health solutions that improve outcomes and reduce disparities for minority populations and underserved communities.

This funding opportunity supports U.S.-based small businesses in developing innovative clinical diagnostic tools that address health disparities and improve healthcare access for diverse populations.

This funding opportunity supports U.S.-based small businesses in developing innovative diagnostic tools to reduce health disparities among diverse patient populations.

This program provides financial assistance to farmers and small rural businesses for implementing renewable energy projects and improving energy efficiency.