Grants for Unrestricted - Federal

This funding opportunity is designed to support innovative research and development projects that improve the manufacturability and scalability of energy storage technologies for stationary applications, helping to reduce production costs and enhance the energy grid's resilience.

This funding opportunity is designed for research institutions and organizations affiliated with the Rocky Mountains Cooperative Ecosystems Studies Unit to investigate remote sensing techniques for monitoring dissolved organic matter in water, ultimately improving water quality management across the United States.

USAID/Cambodia is seeking applications for a Cooperative Agreement from qualified entities to implement the Cambodia Media Development (CMD) Activity. The purpose of this activity is to strengthen and expand the diversity of trustworthy news and information sources available to Cambodians so that they can be better equipped to participate in civic life. The CMD activity contains two main objectives: Objective 1: Institutionalization. Strengthen independent platforms for gathering and disseminating trustworthy news and information to Cambodian audiences. Objective 2: Innovation. Expand the means and methods used to bring Cambodians reliable, independent news and information.Objective 3: Resilience. Build the cohesion, security, and durability of Cambodias independent media sector.

This grant provides funding to local Tanzanian organizations to improve foundational literacy and numeracy for students in grades 1 to 5 through a targeted instruction approach that focuses on individual learning levels.

This grant provides funding exclusively to the Candler County Industrial Authority for upgrading rail infrastructure in Georgia, enhancing safety and efficiency for regional freight operations.

Invasive species pose a significant threat to the ecological, economic, and cultural integrity of Americas lands and waters and the communities they support. Once invasive species are established, it is often challenging and costly to control or eradicate those infestations. In some cases, however, eradication the removal or destruction of an entire population of invasive species from a defined area is both possible and feasible, resulting in substantial ecological and economic benefits. This can include eradication of a founding population of invasive species (e.g., a newly introduced species to a specific area) or eradicating a well-established population. Eradication, while it represents the ideal outcome in most cases, requires consideration of the available eradication techniques, cost, likelihood of success, likelihood of re-invasion, public support, complexity of environmental compliance, and availability of resources. This latter consideration is frequently a barrier to implementing eradication measures that can lead to restoring ecosystem health.Furthermore, successful eradication efforts are often dependent on the use of integrated pest management (IPM) strategies, making well informed decisions, and applying a collaborative approach. IPM is defined as an approach to managing pests that uses biological, cultural, physical, and chemical tools in a way that minimizes health, environmental, and economic risks. Collaboration with relevant parties, such as state, federal, local, tribal, territory, private, and other land managers, is often essential for successful eradication projects.For eradication to be an option, resource managers must have access to effective tools. Therefore, it is important to support both on-the-ground eradication efforts and also the research into and development of tools where they do not exist. DOI encourages leveraging science and technology to increase the likelihood of eradication of invasive species and increase the likelihood of long-term success. As such, proposals will be considered for on-the-ground projects that eradicate an invasive species or those projects that advance research that increases the effectiveness and near-term availability of eradication tools. For example, studies that lead to the development of genetic interventions and physical, mechanical, chemical, and biological eradication tools would be eligible.Examples of the type of work being targeted for this Invasive Species Eradication Funding Opportunity include:Eradication of the invasive annual grass Cenchrus spp. A Weed Risk Assessment for the invasive annual grass Cenchrus spp. in Hawaii identified the species as high risk for many reasons. It thrives and spreads in tropical climates. It is an invasive plant that affects native coastal vegetation and seabird habitat. It has spiny burs that disperse easily via clothing or feathers, reproduces by prolific seed production, and is easily spread by high winds and storms. It reaches maturity in less than one year and persists in the seedbank for one to five years. Cenchrus spp. was introduced to the remote island of Nihoa, a volcanic remnant in the Hawaiian Archipelago with many geographically distinct species including two endemic and endangered passerines and three endemic and endangered plants. Early detection and monitoring indicated that the Cenchrus spp. infestation on Nihoa dramatically increased from just seven plants observed in 2017 to over 600 plants in 2018. This expansion indicated that it was initiating its ascent of the exponential growth curve common in invasive species. Eradication efforts are underway to eradicate Cenchrus spp. from Nihoa via an integrated pest management process (e.g., physical and chemical treatments) coupled with rigorous biosecurity measures to prevent reinvasion.Research on the use of YY technology for invasive fish eradication. The Western Association of Fish and Wildlife Agencies initiated, in 2018, the YY Male Consortium (Consortium) with funding from 13 western states. The Consortium is building upon the work initiated by the State of Idaho to develop YY male broodstock for invasive brook trout. They are developing research broodstock for five additional regionally invasive species, including the common carp, walleye, lake trout, brown trout and Northern pike. Ongoing field evaluations of eradication programs using YY male brook trout in several western states indicate suppression is happening as modeled. In addition, populations in smaller systems are on the verge of documenting total eradication. This work combines multiple control tools using the principles of integrated pest management by suppressing invasive brook trout populations annually through mechanical and/or chemical control, and then stocking the equivalent number of YY males to replace those removed. YY males breed with the wild females, producing only YY males, leading ultimately to an all YY male population and population eradication. Note: This Invasive Species Eradication Funding Opportunity is separate from the Rapid Response Fund for Aquatic Invasive Species Notice of Funding Opportunity (grants.gov announcement number F24AS00175). The Rapid Response Fund for Aquatic Invasive Species is intended to support the planning and deployment of responses to newly detected populations of aquatic invasive species in pursuit of eradicating the population before it becomes established and spreads. This Invasive Species Eradication Funding Opportunity, however, is open to all taxa (see Eligible Taxa section) and can be used for eradication of newly detected populations of terrestrial invasive species, eradication of well-established populations of aquatic or terrestrial invasive species, or for research that advances tools for effective eradication of aquatic or terrestrial invasive species. Bipartisan Infrastructure Law (BIL) Ecosystem Restoration Program and DOI PrioritiesThe Bipartisan Infrastructure Law (also referred to as BIL, or the Infrastructure Investment and Jobs Act (IIJA)), Section 40804 (Ecosystem Restoration) provided funding to DOI for invasive species detection, prevention, and eradication, including conducting research and providing resources to facilitate detection of invasive species at points of entry and awarding grants for eradication of invasive species on non-Federal land and on Federal land. This Invasive Species Eradication Funding Opportunity aims to meet BILs direction to offer grants for eradication of invasive species.This funding opportunity also advances DOIs policy regarding invasive species management (524 DM 1) which identifies eradication undertaken in a cost-effective and environmentally sound manner as one objective of an integrated pest management approach. Additionally, it advances Goal 4 of the DOIs Invasive Species Strategic Plan for 2021-2025 to cost-effectively control or eradicate established invasive species populations to reduce impacts and help restore ecosystems.For this funding opportunity, collaboration with one of DOIs Keystone Initiatives is encouraged, as appropriate. DOI prioritized these Keystone Initiatives as focal areas for transformational conservation efforts across the nation. The Keystone Initiatives advance the Restoration and Resiliency Framework and include:Gravel to GravelGrasslandsHawaiian Forest BirdsKlamath BasinSagebrush EcosystemSaltmarsh, andAppalachiaPurpose and Program Grant Requirements:In Fiscal Year 2024, DOI prioritized BIL funds to establish this Invasive Species Eradication Funding Opportunity within the existing authorities of DOI, to be administered by the USFWS in collaboration with DOI bureaus. Accordingly, the DOI bureaus, through the USFWS, invite proposals to support the eradication of a newly introduced or established species in terrestrial or aquatic habitats of the United States, including the U.S. territories (aquatic habitats include freshwater, wetland, riparian, estuarian, and marine). While preference will be given to proposals that result in eradication of invasive species, research proposals that advance research that increases the effectiveness and availability of eradication tools will be considered. Eradication is defined as the removal or destruction of an entire population of invasive species. For the purposes of this funding opportunity, this means the elimination of all individuals of a distinct population in a geographically defined area that is not contiguous or connected (via natural dispersal) with other populations and that is surrounded by naturally occurring or human-made barriers sufficiently effective to prevent reinvasion as verified using monitoring and inventories. Projects targeted at eradicating a founding population of a terrestrial invasive species or those eradicating established populations of aquatic or terrestrial invasive species will be considered. Eradication can be a key resource management step that then allows other resource management objectives to be achieved, such as habitat restoration or the recovery of Threatened and Endangered Species. This funding opportunity recognizes that eradication of a widespread established invasive species is possible and can be successful late in the invasion stages, but it requires strategic approaches (such as by using IPM) and targeted investments. The intent of this funding opportunity is to promote and invest in those projects with a high likelihood of achieving eradication success and in those that have existing partnerships and plans in place. NOTE: Projects responding to founding populations of aquatic invasive species within the early detection and rapid response context should instead apply for funding through the Rapid Response Fund for Aquatic Invasive Species. Projects addressing established aquatic invasive species infestations with a high likelihood of eradication can apply for this Eradication Funding Opportunity. Proposals submitted for this opportunity should address how the proposed project supports DOIs mission, especially helping to protect vulnerable, high priority, or protected species or areas. Proposals that service underserved, or historically disadvantaged communities are also encouraged. These will be considered among the grant review criteria listed under the Application Review Information section later in this document.

This funding opportunity is designed for partners within the Californian Cooperative Ecosystem Studies Unit to support research on climate-driven range shifts by providing training, facilitating workshops, and conducting data synthesis efforts.

U.S. Embassy Bern invites proposals for programs that strengthen cultural ties between the United States and Switzerland or Liechtenstein through cultural and exchange programming that highlights shared values and promotes bilateral cooperation and dialogue. All programs must include an American cultural element, or connection with (a) U.S. expert/s, organization/s, or institution/s in a specific field that will promote increased understanding of U.S. policy and perspectives. The PDS Small Grants Program is open to applications from Swiss, Liechtenstein, and U.S. organizations and individuals. We especially encourage and will prioritize applications from alumni of U.S. State Department Exchange Programs who are residents of Switzerland or Liechtenstein. Priority Program Areas: 1. Recognizing and countering disinformation and misinformation 2. Diversity, equity, inclusion, and accessibility, with a special focus on: 2.1. Women and girls, in all their diversity, in STEAM fields 2. 2.Increasing visibility, equity, inclusion, and accessibility of underrepresented groups in Switzerland and Liechtenstein, including immigrants, migrants, refugees, and asylees 3. Promoting mobility and knowledge transfer of apprenticeships between Switzerland/Liechtenstein and the United States 4. Strengthening entrepreneurship and economic collaboration between the United States and Switzerland with an emphasis on emerging and women entrepreneurs and business students Participants and Audiences: 1. Swiss and Liechtenstein residents 2. Underrepresented groups 3. Swiss and Liechtenstein youth aged 16 to 25 4. Emerging and established professionals and leaders in the priority program areas mentioned above Applicants should read the full description of the statement, attached here or on our website: https://ch.usembassy.gov/embassy/jobs/proposals/

This Funding Opportunity Announcement (FOA) aligns with DOEs Office of Resource Sustainabilitys Methane Emissions Mitigation and Quantification Program to minimize emissions of methane during production, processing, and transportation across the oil and natural gas industry, with the goal of eliminating methane emissions from carbon-based fuel supply chains by 2030. Effective methane emissions mitigation strategies are dependent upon accurate quantification of both intentional and fugitive emissions from all elements across the natural gas infrastructure, including low producing oil and gas wells. Therefore, there is a continual need to maintain a state-of-the-industry understanding methane emissions mitigation opportunities and operation performance, through collection of empirical data, across oil and natural gas production and delivery regions of the United States. This is to maximize the value of these efforts to the public with the goals of reducing GHG emissions and improving environmental health and engagement of the affected public, (largely in disadvantaged or frontline communities). The FOA objective is to make funds available to a variety of entities for the purpose of mitigating methane emissions from marginal conventional wells (MCWs) and other oil and natural gas assets; accelerating the commercialization, scale-up and application of innovative methane emissions reduction technologies; and advancing the characterization and reduction of methane emissions through multi-scale, measurement-informed data collection and analysis. Modification 000001 is issued to update Section I.B. of the FOA to include clarifications regarding: Objectives and Background under AOI 3b; Activities Not of Interest under AOI 1 (1a, 1b, and 1c) and AOI 3 (3a and 3b); and well site and field test location as it relates to AOI 2 (2a, 2b, and 2c)

This grant provides funding to civil society organizations and non-governmental groups in Uganda to strengthen media, promote civic education, and engage youth in governance processes.

This grant provides funding to organizations working in the Eastern and Southern Caribbean to develop programs that help youth avoid gang involvement and related violence through community support, education, and rehabilitation initiatives.

This funding opportunity is designed for partners affiliated with the Colorado Plateau Cooperative Ecosystem Studies Unit to conduct research on drought conditions and sagebrush habitat resilience in dryland ecosystems.

The "Carbon Capture, Removal, and Conversion Test Centers" grant from the U.S. Department of Energy aims to fund the establishment and expansion of test centers for developing and commercializing technologies that capture, remove, and convert carbon dioxide emissions from large sources like power plants and industrial facilities, in an effort to achieve a carbon-free power sector by 2035 and a net-zero greenhouse gas economy by 2050.

This grant invites organizations and companies to collaborate on innovative health solutions aimed at reducing disease and mortality rates in low-and-middle-income countries.

This grant provides funding to the American Association of State Highway Transportation Officials to promote innovative practices in highway and transportation programs across the United States.

USAID Vietnam intends to issue a Cooperative Agreement for USAID/ Vietnam's Combating Illegal Wildlife Trafficking activity. The anticipated dollar range for the five-year activity is between $14 and $16 million. Attached is the draft Program Description (PD) of the activity. We invite your comments/feedback to this draft PD. Any responses should be submitted to Ms. Huyen Dang at [email protected] not later than 9:00 Hanoi time, November 23, 2020 and all responses will be considered prior to finalizing the PD. Please be advised that this is not a Request for Applications (RFA) and does not constitute a commitment on the part of the US. Government to make an award. We anticipate releasing the Request for Applications (RFA) at the end of November, 2020 with a closing date for receipt of applications in mid-January of 2021. We look forward to receiving your comments/feedback. Thank you very much for your time and interest in the activity.

This funding opportunity is designed for research institutions affiliated with the Southern Appalachian Mountains CESU to study climate adaptation in oak-dominated ecosystems and their impact on wildlife, with a focus on species distribution and resource management.

The FY24 ALSRP Pilot Clinical Trial Award supports the rapid implementation of clinical trials with the potential to have a significant impact on the treatment or management of ALS. Projects may range from phase 1 to small-scale phase 2 trials and should aim to de-risk and inform the design of more advanced trials by investigating safety, feasibility, biomarker application, and therapeutic efficacy in relevant patient populations. Clinical trials may be designed to evaluate promising drugs, biologics, or devices with anticipated therapeutic impact that is supported by strong scientific rationale and existing preliminary studies and/or preclinical data. Clinical trials aimed to improve aspects of patient care and ALS symptom management are also applicable to this award mechanism.Funding from this award mechanism must support a clinical trial. A clinical trial is defined as a research study in which one or more study participants are prospectively assigned to one or more interventions (which may include a placebo or another control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes. For more information, a Human Subject Resource Document is provided at https://cdmrp.health.mil/pubs/pdf/Human%20Subjects%20Resource%20Document_DEC2022.pdf. Principal Investigators (PIs) seeking funding for a preclinical research project should consider one of the other FY24 ALSRP program announcements being offered. Studies that do not seek to measure safety, effectiveness, and/or efficacy outcome(s) of an intervention are not considered clinical trials.Projects proposing a therapeutic intervention (drug, biologic, and/or device) must incorporate biomarkers specific to the intervention into the trial design. Applicants must clearly describe a biomarker-driven approach and its potential to de-risk and improve the design of anticipated later-stage trials. For further description, see Attachment 13, Biomarker Statement. Biomarker development and characterization can include target engagement biomarkers, pharmacodynamic biomarkers to measure the biological effect of an investigational therapeutic, and/or predictive/cohort-selective biomarkers that indicate whether a specific therapy will be effective in an individual patient or patient subgroup.Key aspects of the FY24 ALSRP Pilot Clinical Trial Award mechanism include:Impact: Potential impact from a pilot clinical trial is not whether an intervention is ready at the conclusion of the trial, but rather if the outcomes will improve and accelerate future larger trials or clinical care and symptom management. Applications submitted to this award can have outcomes that focus on specific subpopulations of ALS patients or potentially even individual patients.Biomarker-Driven Interventions: Therapeutic outcomes should directly and substantially de-risk and inform the design of anticipated later-phase trials of the intervention under investigation.Clinical Care: Improving aspects of clinical care and symptom management should have near-term impact on patients. All interventions must offer significant potential impact for individuals affected by ALS; however, this may include just specific subpopulations or potentially even individual patients.Employing Community Collaborations to Optimize Research Impact Is Required. Research funded by the FY24 ALSRP Pilot Clinical Trial Award should be responsive to the needs of people with ALS, their families, and/or their care partners. Research teams are therefore required to establish and utilize effective and equitable collaborations and partnerships with Community members to maximize impact potential of the proposed research. These collaborations are expected to facilitate accessible, efficient, and humane clinical trials. Applications to the FY24 ALSRP Pilot Clinical Trial Award must name at least one Community partner (e.g., person with ALS, family member and/or caregiver, representative of a community-based organization) who will provide advice and consultation throughout the planning and implementation of the research project. Scientific researchers and Community members will collaborate and contribute equitably on all aspects of the project, which may include needs assessment, planning, research intervention design, implementation, evaluation, and dissemination. Interactions with other team members should be well integrated and ongoing, not limited to attending seminars and semi-annual meetings. Examples for implementing collaborative research approaches include:Person Living with ALS, Family Member, and/or Caregiver: The research team includes a person with ALS, their family member, or caregiver (past or present) as a project advisor who will provide advice and consultation throughout the planning and implementation of the research project.Partnership with a Community-Based Organization: The research team establishes partnerships with at least one Community-based organization that provides advice and consultation throughout the planning and implementation of the research project. Community-based organizations may include advocacy groups, service providers, policymakers, or other formal organizational stakeholders.Community Advisory Board: A Community advisory board is composed of multiple Community stakeholders and can take many forms, from a board of people with ALS, their family members, or caregivers to a coalition of Community-based organizations or any combination thereof. As with people living with ALS and organizational partners, the Community advisory board provides advice and consultation throughout planning and implementation of the research project.Clinical Trial Start Date and Intervention Availability: The proposed clinical trial is expected to begin no later than 12 months after the award date or 18 months after the award date for Food and Drug Administration (FDA)-regulated studies. The application should demonstrate the documented availability of and access to the drug/compound, device, and/or other materials needed, as appropriate, for the proposed duration of the study.Study Population: The application should demonstrate the availability of and access to a suitable patient population that will support a meaningful outcome for the study. The application should include a discussion of how accrual goals will be achieved, as well as the strategy for inclusion of women and minorities in the clinical trial appropriate to the objectives of the study.Research Personnel and Environment: The application should demonstrate the study teams expertise and experience in all aspects of conducting clinical trials, including appropriate statistical analysis, knowledge of FDA processes (if applicable), and data management. The application should include a study coordinator(s) who will guide the clinical protocol through the local Institutional Review Board (IRB) of record and other federal agency regulatory approval processes, coordinate activities from all sites participating in the trial, and coordinate participant accrual. The application should show strong institutional support and, if applicable, a commitment to serve as the FDA regulatory sponsor, ensuring all sponsor responsibilities described in the Code of Federal Regulations, Title 21, Part 312 (21 CFR 312), Subpart D, are fulfilled.Statistical Analysis and Data Management Plans: The application should include a clearly articulated statistical analysis plan, a power analysis reflecting sample size projection that will answer the objectives of the study, and a data management plan that includes use of an appropriate database to safeguard and maintain the integrity of the data. If FDA-regulated, the trial must use a 21 CFR 11-compliant database and appropriate data standards. For more on data standards, see https://www.fda.gov/downloads/Drugs/DevelopmentApprovalProcess/ FormsSubmissionRequirements/ElectronicSubmissions/UCM511237.pdf.Transition Plan: Applications should include a transition plan (including potential funding and resources) showing how the intervention will progress to the next clinical trial phase and/or improve current standards of care after the successful completion of the FY24 ALSRP Pilot Clinical Trial Award.Milestone meeting: The Principal Investigator (PI) will be required to present an update on progress toward accomplishing the goals of the award at annual, virtual In Progress Review meetings to be held during the period of performance. The PI should ideally include their Community collaboration partner(s) in the meeting. The In Progress Review Meeting will be attended by members of the ALSRP Programmatic Panel, CDMRP staff, the USAMRAA Grants/Contracts Officer, and other stakeholders.

This program seeks to strengthen citizen trust in Kenya's electoral processes by supporting the government, civil society, and other stakeholders in ensuring free, fair, and peaceful elections during the 2027 electoral cycle.

United States Agency for International Development (USAID) Mozambique is planning the Ensuring Social Protection by Empowering and building Resiliency for Adolescents, Nuclear families, Children, and caregivers affected by HIV/AIDS (ESPERANA) Activity, focused on improving health outcomes of households vulnerable to and impacted by HIV in Manica, Tete and Sofala.