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Grants for Small businesses - Federal Environment

Explore 132 grant opportunities

Lighting Prize (L-Prize)
$10,000,000
U.S. Department of Energy
Federal

Application Deadline

Aug 5, 2025

Date Added

Aug 19, 2024

This initiative provides up to $10 million in prizes to innovators developing advanced LED lighting solutions that improve energy efficiency, quality, and accessibility for commercial use.

Energy
Small businesses
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Aug 16, 2023

This funding opportunity supports students enrolled in dual-degree medical and research training programs, helping them develop into independent physician-scientists through mentored research and clinical training.

Education
State governments
High-efficiency Nitrogen Oxidation (HNO3)
Contact for amount
U.S. Department of Defense (DARPA - Defense Sciences Office)
Federal

Application Deadline

Feb 5, 2026

Date Added

Dec 2, 2025

This funding opportunity is designed for researchers and organizations developing innovative methods to produce nitric acid more efficiently and sustainably, reducing reliance on traditional ammonia-based processes.

Science and Technology
State governments
SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance and Late Stage Development (SB1, Clinical Trial Not Allowed)
$2,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 5, 2025

Date Added

Apr 4, 2025

This funding opportunity provides financial support to U.S.-based small businesses that have previously received NIH Phase II or Phase IIB awards, helping them advance their research projects toward commercialization through technical assistance and late-stage development activities.

Education
Small businesses
Early-stage Biomedical Data Repositories and Knowledgebases (R24 Clinical Trial Not Allowed)
$350,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 25, 2026

Date Added

Aug 30, 2023

This funding opportunity supports the development of new or improved biomedical data repositories and knowledgebases to enhance research and promote data sharing in the biomedical community.

Education
State governments
ROSES 2025: A.5 Earth Venture Suborbital-4 Snow4Flow Science Team
$5,000,000
National Aeronautics & Space Administration (NASA Headquarters)
Federal

Application Deadline

Sep 9, 2025

Date Added

Jul 12, 2025

This funding opportunity is designed for researchers and teams focused on improving our understanding of snow accumulation and ice flow dynamics in glaciers across the Northern Hemisphere, with an emphasis on airborne and ground-based observations, modeling, and data synthesis.

Environment
Public and State controlled institutions of higher education
PHS 2024-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 5, 2025

Date Added

Jul 5, 2024

This funding opportunity supports U.S.-based small businesses in health-related fields to develop innovative technologies, with a focus on projects that can successfully transition to commercialization.

Education
Small businesses
Energy Storage Innovations Prize
$50,000
U.S. Department of Energy (DOE) Office of Electricity (OE)
Federal

Application Deadline

Sep 10, 2025

Date Added

Dec 31, 2024

This grant provides funding for individuals and organizations to develop innovative energy storage solutions that cater to unique applications in underserved communities and extreme climates, promoting grid modernization and reliability.

Science and Technology
Small businesses
Microsystems Exploration
$2,000,000
Defense Advanced Research Projects Agency (DARPA)
Federal

Application Deadline

Oct 15, 2025

Date Added

Mar 18, 2025

This funding opportunity supports innovative research proposals from small businesses, academic institutions, and research organizations to develop high-risk, high-reward microsystem technologies for defense applications.

Science and Technology
Private institutions of higher education
Fiscal Year (FY) 2025 Mississippi Conservation Delivery for Outreach, Education, and Technical Assistance
$999,999
U.S. Department of Agriculture (Natural Resources Conservation Service)
Federal

Application Deadline

Mar 16, 2025

Date Added

Jan 15, 2025

This funding opportunity provides financial support for conservation projects in Mississippi, focusing on outreach, education, and technical assistance to help socially disadvantaged and beginning farmers adopt sustainable agricultural practices.

Agriculture
State governments
Building Sustainable Software Tools for Open Science (R03 Clinical Trial Not Allowed)
$300,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

May 23, 2025

Date Added

Jul 18, 2024

This funding opportunity supports researchers and organizations in improving and sustaining software tools for biomedical and health-related research by adopting best practices and enhancing collaboration within the scientific community.

Education
State governments
Large Animal and Solar System Operations (LASSO) Prize
$8,200,000
U.S. Department of Energy (Solar Energy Technologies Office (SETO))
Federal

Application Deadline

Mar 6, 2025

Date Added

Jul 29, 2024

This grant provides financial support for innovative projects that integrate solar energy production with cattle grazing, aimed at U.S.-based teams of solar developers and cattle ranchers.

Energy
Nonprofits
Notice of Intent to Issue Infrastructure Investment and Jobs Act (IIJA): Mines and Metals Capacity Expansion Piloting By-Product Critical Minerals and Materials Recovery at Domestic Industrial Facilities
$50,000,000
U.S. Department of Energy (National Energy Technology Laboratory)
Federal

Application Deadline

Dec 15, 2025

Date Added

Aug 14, 2025

This funding opportunity is designed to support domestic industrial facilities in recovering critical minerals and materials from byproducts, enhancing the U.S. supply chain and reducing reliance on foreign sources.

Energy
For profit organizations other than small businesses
Microsystems Technology Office (MTO) Office-wide
$2,000,000
U.S. Department of Defense (DARPA - Microsystems Technology Office )
Federal

Application Deadline

Mar 2, 2026

Date Added

May 10, 2024

This funding opportunity supports innovative research in microsystems technology, targeting a wide range of applicants including universities, small businesses, and minority institutions, to develop advanced microelectronic systems that enhance U.S. national security.

Science and Technology
For profit organizations other than small businesses
Epitranscriptomics Crosstalks and Toxicants (EPCOT) (R01 Clinical Trials Not Allowed)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 6, 2025

Date Added

Nov 15, 2024

This funding opportunity supports innovative research on how environmental toxicants impact RNA modifications and their role in health issues, targeting universities, nonprofits, and for-profit organizations involved in related studies.

Environment
State governments
Private Sector Collaboration Pathway (PSCP) Jordan Addendum
$10,000,000
Agency for International Development (Jordan USAID-Amman)
Federal

Application Deadline

Apr 26, 2025

Date Added

Apr 17, 2024

This initiative provides funding opportunities for private sector entities in Jordan to collaborate with USAID in addressing key development challenges, focusing on economic growth, water security, governance, education, and the empowerment of women and youth.

Business and Commerce
For profit organizations other than small businesses
Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)
$50,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Apr 4, 2025

This funding opportunity provides financial support for researchers to investigate the ethical, legal, and social implications of human genetic and genomic research, encouraging innovative studies that address emerging issues in the field.

Education
State governments
NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 19, 2024

This funding opportunity supports a wide range of research projects aimed at advancing medical knowledge and improving health, available to various organizations including universities, nonprofits, and businesses.

Education
State governments
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Apr 3, 2025

This funding opportunity supports research on the ethical, legal, and social implications of human genetic and genomic research, encouraging diverse teams to explore issues like data governance, informed consent, and equity in genomic applications.

Education
State governments
The Conservation Stewardship Program
Contact for amount
USDA Natural Resources Conservation Service
Federal
Rolling

Application Deadline

Not specified

Date Added

Oct 16, 2025

This program provides financial rewards to agricultural producers in Montana who implement conservation practices that improve natural resources while maintaining land productivity.

Agriculture
Individuals