Federal Health Grants

This funding opportunity provides financial support to organizations in rural areas to develop and implement programs that address behavioral health challenges among youth while promoting careers in behavioral health.

This funding opportunity supports community-based research projects that aim to improve health outcomes and reduce health disparities among minority populations through collaborative interventions.

This funding opportunity supports research that explores the effects of aging on individuals living with HIV, focusing on improving health outcomes and management strategies for this population.

Reissue of PAR-20-119. This FOA encourages applications to advance the discovery, preclinical development, and proof of concept (PoC) testing of new, rationally based candidate agents and neurostimulation approaches to treat mental disorders, substance use disorders (SUDs) or alcohol use disorder (AUD), and to develop novel ligands and circuit-engagement devices as tools to further characterize existing or to validate new drug/device targets. Partnerships between academia and industry are strongly encouraged. This FOA supports a research program of multiple projects directed toward a specific major objective, basic theme or program goal, requiring a broadly based, multidisciplinary and often long-term approach. Projects seeking support for a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies should consider the companion U01 FOA.

This funding opportunity provides financial support for U.S.-based institutions to develop and implement innovative strategies that improve diagnostic accuracy and safety in outpatient healthcare settings, particularly for underserved populations.

This funding opportunity is designed to support research that gathers timely feedback from healthcare providers and the public on important immunization issues to improve vaccine recommendations and coverage strategies.

This funding opportunity supports research projects that explore and address the health disparities related to HIV and substance use among underserved racial and ethnic minority populations in the U.S.

The overall goal of this initiative is to support the mentored training of a sustainable critical mass of bioethics scholars in low and middle-income country (LMIC) research intensive institutions with the capabilities to conduct original empirical or conceptual ethics research that addresses challenging issues in health research and research policy in these countries as well as provide research ethics leadership to their institutions, governments and international research organizations. FIC will support LMIC-U.S. collaborative institutional bioethics doctoral and postdoctoral research training programs that incorporate mentored research, advanced theoretical didactic courses and ethics career skills training components to prepare multiple individuals for positions of ethics scholarship and leadership in health research institutions in LMICs. This Funding Opportunity Announcement (FOA) allows appointment of Trainees (D43) proposing to serve as the lead investigator of an independent clinical trial; or proposing a separate ancillary clinical trial; or proposing to gain research experience in a clinical trial led by another investigator, as part of their research and career development.

The "Materials to Enhance Training in Experimental Rigor (METER)" grant aims to support the creation of innovative educational materials for an online platform, designed to improve understanding and application of rigorous biomedical research principles among researchers and scientists at different career stages.

This funding opportunity supports innovative research projects aimed at improving health outcomes and quality of life for individuals with Down syndrome, inviting a diverse range of applicants from various sectors to propose groundbreaking ideas.

This funding opportunity supports research projects that investigate individual differences in pain experiences and treatment responses, aiming to develop personalized pain management strategies while addressing the opioid crisis.

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this R25 program is to support educational activities that foster a better understanding of biomedical, behavioral and clinical research and its implications. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on research experiences for high school or undergraduate students or science teachers during the summer academic break. The proposed program needs to fit within the mission of the participating IC that the application is being submitted to and should not have a general STEM focus (see below and Table of IC-Specific Information and Points of Contact).

This program provides funding to early-career medical and dental professionals to help them start research careers focused on aging and geriatric health.

This funding opportunity supports multi-site clinical trials aimed at testing high-risk medical interventions for diseases related to diabetes, digestive disorders, and kidney health, targeting a wide range of eligible organizations including universities, nonprofits, and businesses.

This funding opportunity supports U.S.-based organizations in evaluating the impact of upcoming public policies and programs that aim to improve health behaviors and reduce chronic disease risk factors through behavioral changes.

U.S. Embassy Nigeria through the U.S. Presidents Emergency Plan for AIDS Relief (PEPFAR) Coordination Office of the Bureau of Global Health Security and Diplomacy at the U.S. Department of State announces an open competitive opportunity for organizations to apply for funding to implement community-led monitoring or a virtual spaces intervention among priority populations for HIV prevention and treatment, including Key Populations (KP) and Adolescent and Young People (AYP). For HIV to no longer be a public health threat by 2030 in Nigeria, the populations at highest risk must know their HIV status, receive lifesaving HIV prevention and treatment, and reach viral suppression if they are HIV-positive. Data show that HIV prevention and treatment efforts should be focused on AYP and KPs. Key Populations include men who have sex with men, transgender individuals, sex workers, people who inject drugs (PWID), and people in prisons and other closed settings. Under this opportunity, the PEPFAR Coordination Office seeks to address pillar 1 of the 5x3 strategy, health equity for priority populations. Youth make up a significant proportion of the more than 32.9 million Nigerians reported to be active users of social media. AYP-led CSOs in the country have identified a gap with the lack of structured sexual health and HIV messaging and interventions on these platforms. Virtual online space is a digital environment that enables people to, socialize, interact, and gather information using available technologies and non-necessarily requiring a physical space to operate. Interventions on a virtual space may include, but not be limited to phone services such as calls and messaging, mobile applications, websites, and social media channels. Through Virtual Spaces Interventions, PEPFAR Nigeria intends to address the gaps in the use of online platforms and spaces by meeting KP and AYP where they are; providing them with HIV and other relevant health information; facilitating referrals and linkages to health facilities for person-centered HIV prevention, treatment, and other health care services. Prioritizing these spaces as a compliment of existing health systems in the on-going efforts to increase program reach among AYP and KPs, and to use this space to facilitate health promotion, HIV testing and case-finding, and drive access to other health services in a confidential manner. This program seeks to increase access to quality, concise and accurate HIV and health related messaging, facilitate active referrals and linkages to spaces and locations which can provided access to strategic HIV and other health services for prevention, treatment and care interventions targeted at AYP and KPs by leveraging on virtual spaces utilized by adolescents and young persons. The program will support community-led monitoring efforts among AYP and KP-led groups using platforms such as iMonitor + to ensure that HIV positive individuals among these priority populations are receiving high quality care and treatment services, identify any challenges, barriers, and/or gaps to care, and to report findings to PEPFAR to inform service delivery.

This funding opportunity supports researchers conducting time-sensitive studies that enhance ongoing clinical projects related to arthritis, musculoskeletal, and skin diseases, aiming to improve understanding and treatment of these conditions.

This Notice of Funding Opportunity (NOFO) announces the opportunity to apply for funding under the Health Center Programs Service Area Competition (SAC). The purpose of this funding is to ensure continuity of care in the communities and populations currently served by the Health Center Program. See Program Requirements and Expectations for more details.

The purpose of this program is to support Community-Led Monitoring of HIV services at selected health service sites to promote improvements in the HIV response under the Presidents Emergency Plan for AIDS Relief (PEPFAR).Community-led monitoring (CLM) is a technique initiated and implemented by local community-based organizations and other civil society groups, networks of key populations (KP), people living with HIV (PLHIV), and other affected groups or other community entities that gathers quantitative and qualitative data about HIV services. The focus is on getting input from recipients of HIV services, especially key populations and underserved groups, in a routine and systematic manner that will translate into action and change. CLM is central to PEPFAR’s client-centered approach because it helps puts communities, their needs, and their voices at the center of the HIV response. Why does PEPFAR support Community-Led Monitoring? CLM conducted by local civil society organizations helps PEPFAR programs and health institutions diagnose and pinpoint persistent problems, challenges, and barriers related to HIV service access, uptake, and retention at the community and facility level. CLM aims to improve HIV service delivery and client outcomes by identifying data-driven solutions to overcome barriers and ensure beneficiaries receive optimal client-centered HIV services in a manner that is productive, collaborative, respectful, and solutions-oriented. Who does PEPFAR fund for CLM? PEPFAR-supported CLM is conducted objectively by independent, local community organizations. PEPFAR implementing partners who currently work on service delivery at the site level are not eligible for CLM funding, even if they will sub-grant to a local civil society organization. What is monitored and how? Systematic and routine, with follow up and continuous improvement. Tailored to the needs identified by local communities, with communities directly determining the scope. Allow for community and host country government development of the specific metrics, measures, or tools to be used for CLM. Metrics or measures should be tailored to a given context and address the specific needs and concerns of community members. Triangulated with, but not duplicative of, other PEPFAR data streams. Community-led monitoring data should reflect an ‘added value’ and not duplicate collection of routine data already available to PEPFAR. ‘Added value’ monitoring data includes: information from beneficiaries about their experience with the health facility, information about barriers and enablers to access and retention in services, etc. Productive, collaborative, respectful, and solutions-oriented. Action-oriented with an associated follow-up process with the health facility that is overseen by U.S. government staff, committed to corrective public health action, and involves community advocacy to improve service outcomes

This grant provides funding for collaborative research projects that investigate how RNA modifications influence cancer development by altering protein synthesis, requiring expertise in RNA biology and cancer research.