Federal Health Grants

This funding opportunity provides $3.5 million over five years to organizations that will create a national resource hub for improving healthcare access and outcomes in rural communities across the United States.

This funding opportunity supports institutions in training clinical scientists focused on cancer research, enabling them to lead or participate in clinical trials as part of their career development.

(Reissue PAR-21-058). The purpose of this Program Announcement (PAR) is to enable clinical validation of strong candidate biomarkers for neurological diseases and conditions. Specifically, the goal of this PAR is to enable the rigorous validation of biomarker measurements within the clinical population of interest to establish the positive and negative predictive values of the candidate biomarker consistent with FDA guidelines. This PAR assumes that 1) a candidate biomarker has already been identified, 2) detection method technology has already been developed and analytically validated, and 3) the research and/or clinical need and potential context of use has been identified.

The purpose of this initiative is to support research to improve health and promote health equity in rural populations. Rural populations experience high rates of many causes of morbidity and disability, and high and increasing rates of premature death. Meaningful and sustained improvements in the health of rural populations require effective solutions to address the underlying causes. Applications responding to this Notice of Funding Opportunity (NOFO) should develop, adapt, or implement intervention strategies addressing social determinants of health (SDOH) to improve health and promote health equity in rural populations. This funding opportunity encourages studies that use a wide range of methodological approaches that enhance access to, and acceptability and effectiveness of, interventions in rural populations, such as community-engaged research approaches that build on the strengths of rural communities.

This funding opportunity provides financial support to public agencies and nonprofit organizations to deliver essential primary health care services to underserved communities across the United States.

This funding opportunity supports community-led research initiatives aimed at developing and evaluating prevention strategies for intimate partner violence and sexual violence in high-risk communities, particularly among marginalized groups.

This grant provides funding for innovative, interdisciplinary research projects that aim to advance understanding and treatment of diseases related to diabetes, digestive disorders, liver diseases, metabolic and nutritional disorders, kidney and urologic diseases, and obesity.

This grant provides funding for research and development projects aimed at improving the equipment and support systems for U.S. Army soldiers, focusing on enhancing their survivability, mobility, and overall effectiveness in the field.

This funding opportunity provides financial support to state, local, and tribal governments to prevent childhood lead poisoning and improve blood lead level surveillance in high-risk communities.

This funding opportunity provides financial support to state and local governments, educational institutions, nonprofits, and other organizations to implement strategies that promote better nutrition and physical activity, ultimately reducing chronic disease risks in their communities.

This grant provides funding for researchers studying the development of brain circuits and their relationship to behavior in rodents and non-human primates, focusing on how these processes influence mental health across different life stages.

This funding opportunity supports institutions in developing training programs for predoctoral and postdoctoral researchers focused on advancing knowledge and skills in aging research, aiming to prepare a diverse group of scientists for careers in this critical field.

The purpose of this funding opportunity is to develop artificial intelligence tools and experimental assays to identify new pharmacotherapeutics with lower toxicity and higher efficacy for substance use disorders (SUD) Areas of interest include but are not limited to: 1) Development of AI tools to identify potential target combinations, design new molecules, conduct virtual preclinical studies to predict efficacy and toxicity, and model in vitro and in vivo polypharmacology 2) Development of assays to assess the effects of compounds on multiple targets or functions

This funding opportunity is designed to support the Frederic Rieders Family Renaissance Foundation in advancing research, education, and reporting on emerging synthetic drugs and their impact on public health and safety.

This grant provides funding to eligible institutions, particularly Historically Black Colleges and Universities, Tribal Colleges and Universities, and IDeA program participants, to develop programs that train diverse clinician-scientists who can address the nation's biomedical research needs.

This grant provides funding to support the Tanzanian government's efforts to strengthen public health systems, improve disease detection and response, and enhance laboratory capabilities to better manage health threats.

This funding opportunity supports U.S. institutions in developing educational programs that provide undergraduate and early-stage graduate students with hands-on research experiences in kidney technology development and entrepreneurship.

This funding opportunity supports innovative research and development in biological technologies that enhance national security, targeting universities, nonprofits, small businesses, and industry participants, particularly those with commercial potential.

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. This Funding Opportunity Announcement (FOA) is soliciting Transformative Research Award applications to support individual scientists or groups of scientists proposing groundbreaking, exceptionally innovative, original, and/or unconventional research that has the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies related to Down syndrome. For the program to support the best possible researchers and research, applications are sought which reflect the full diversity of the nations research workforce. Individuals from diverse backgrounds, including those from underrepresented groups and from the full spectrum of eligible institutions in all geographic locations are strongly encouraged to apply to this Funding Opportunity Announcement. Applications are welcome in all topics relevant to Down syndrome-related research or its co-occurring conditions. No preliminary data are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in research related to Down syndrome.

The National Institutes of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) with other NIH Institutes and Centers (ICs), intends to publish a new Notice of Funding Opportunity (NOFO) to solicit applications for multi-PI team-based, challenging, high impact projects to improve understanding of mechanisms of chronic pain in children and adolescents and to accelerate the development of age appropriate, patient/family centered prevention and therapeutic approaches. This research will seek to advance an integrated understanding of the biological, psychological, and social factors that contribute to pediatric chronic pain. NIH is interested in pain research in infants, children, and adolescents that includes those with intellectual and physical disabilities and/or those who experience health disparities (e.g., diverse race/ethnicity, sexual and gender minorities, socioeconomically disadvantaged, medically underserved communities, people with limited English proficiency). NIH encourages applicants to consider community-engaged research and interdisciplinary, collaborative applications to be developed in partnership with patient communities and/or community organizations where possible. The long-term goal is to develop improved knowledge of specific pediatric pain conditions as well as pain associated with diverse diseases/disorders, to improve understanding of pain in the context of child development and to facilitate the stratification of patients with specific pain conditions and co-morbidities to accelerate chronic pain prevention and therapeutic clinical trials. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The NOFO is expected to be published in May 2024 with an expected application due date in Fall 2024. This NOFO will utilize the UC2 Research Project Cooperative Agreements activity code. Details of the planned NOFO are provided below.