Grants for Nonprofits - Science and Technology

The FY24 PCRP Data Science Award mechanism supports research where quantitative and analytical approaches, processes, and/or systems are developed and/or used to obtain knowledge and insight from large and/or complex sets of prostate cancer data. If successful, the studies will enable progress toward addressing one or more of the FY24 PCRP Overarching Challenges. It is expected that any resources, tools, or computational processes generated by this award will be openly shared with the prostate cancer research and patient community. This mechanism is intended to fund research built upon the logic, concepts, and methods of one or more of the following research areas as they pertain to prostate cancer: Computational biology Bioinformatics Artificial intelligence and machine learning Epidemiology Analysis of omics data Medical imaging Digital pathology Analysis of other clinically annotated datasetsApplications may combine diverse data types for integrative analysis to increase knowledge about prostate cancer with respect to the FY24 PCRP Overarching Challenges. Applications that propose to develop resources or tools that allow research, clinical care, and patient community access to standardized and harmonized datasets for real-time clinical care applications are of particular interest; however, this award must not be used to support the development of new datasets. Studies utilizing data derived from large patient studies that include long-term health records or repositories with well-annotated and high-quality biospecimens are encouraged.Key Features: Research Approach: Applications may propose development of a new data-science-driven tool or apply an existing tool or method to gather and analyze information from large datasets with the intent of advancing prostate cancer research and patient care relative to the FY24 PCRP Overarching Challenges. Inclusion of preliminary data to support the scientific rationale and feasibility of research approaches is strongly encouraged, but not required. Any preliminary data provided should be from the laboratory of the Principal Investigator(s) (PI[s]) or member(s) of the collaborating team. Applicants are encouraged to include plans for rigorous validation, benchmarking, comparisons, and/or evaluations to assess the quality or utility of the tools and/or approaches that will be used or developed under this award. Any datasets used in the study design must be from established, retrospective databases and be sufficient in size to provide appropriate analytical and statistical power. Prospective recruitment of human subjects and/or clinical trials is not allowed under this funding opportunity. Applicants are expected to provide documentation demonstrating access to the appropriate datasets and/or patient samples in numbers sufficient to achieve robust results. Impact: Applications are required to clearly communicate how the proposed quantitative and/or analytical approaches, processes, and/or systems will address and provide a solution to one or more of the FY24 PCRP Overarching Challenges. The potential impact of the research, both short- and long-term, should be clearly described, including how the anticipated outcomes or products are distinct from existing research efforts in this area and/or how they will significantly outperform current approaches in this area. High-impact research will, if successful, significantly advance prostate cancer research and/or patient care. Data and Resource Sharing Plan: It is expected that any resources, tools, and computational processes that are developed under this award will be openly shared with the prostate cancer research and patient community. Plans must be provided for how additional data generated by future studies will be incorporated to further inform and refine the data science tools, processes, and/or methods generated and/or used in this study. Refer to the CDMRPs Policy on Data Resource Sharing located on the Electronic Biomedical Research Application Portal (eBRAP) Funding Opportunities Forms web page https://ebrap.org/eBRAP/public/Program.htm for more information about the CDMRPs expectations for making data and research resources publicly available.Partnering PI Option: The FY24 PCRP Data Science Award encourages applications that include meaningful and productive collaborations between investigators. The PIs may have expertise in similar or disparate scientific disciplines, but each PI is expected to bring distinct contributions to the application; collaborations between data scientists and clinicians are highly encouraged. The Partnering PI Option is structured to accommodate two PIs. One PI will be identified as the Initiating PI and will be responsible for the majority of the administrative tasks associated with application submission. The other PI will be identified as a Partnering PI. Both PIs should contribute significantly to the development and execution of the proposed research project, including the Project Narrative, Statement of Work (SOW) and other required components. If recommended for funding, each PI will be named on separate awards to the recipient organization. Each award will be subject to separate reporting, regulatory, and administrative requirements. For individual submission requirements for the Initiating and Partnering PI, refer to Section II.D.2, Content and Form of the Application Submission.A congressionally mandated Metastatic Cancer Task Force was formed with the purpose of identifying ways to help accelerate clinical and translational research aimed at extending the lives of advanced state and recurrent patients. As a member of the Metastatic Cancer Task Force, the CDMRP encourages applicants to review the recommendations (https://health.mil/Reference-Center/Congressional-Testimonies/2018/05/03/Metastatic-Cancer-Research) and submit research ideas to address these recommendations provided they are within the limitations of this funding opportunity and fit within the FY24 PCRP priorities.Innovative research involving nuclear medicine and related techniques to support early diagnosis, more-effective treatment, and improved health outcomes of active-duty Service Members and their Families is encouraged. Such research could improve diagnostic and targeted treatment capabilities through noninvasive techniques and may drive the development of precision imaging and advanced targeted therapies.Applications from investigators within the military services and applications involving multidisciplinary collaborations among academia, industry, the military services, the U.S. Department of Veterans Affairs (VA), and other federal government agencies are highly encouraged. These relationships can leverage knowledge, infrastructure, and access to unique clinical populations that the collaborators bring to the research effort, ultimately advancing research that is of significance to Service Members, Veterans, and/or their Families. If the proposed research relies on access to unique resources or databases, the application must describe the access at the time of submission and include a plan for maintaining access as needed throughout the proposed research.All projects should adhere to a core set of standards for rigorous study design and reporting to maximize the reproducibility and translational potential of clinical and preclinical research. The standards are described in SC Landis et al., 2012, A call for transparent reporting to optimize the predictive value of preclinical research, Nature 490:187-191 (http://www.nature.com/ nature/journal/v490/n7419/full/nature11556.html). While these standards are written for preclinical studies, the basic principles of randomization, blinding, sample-size estimation, and data handling derive from well-established best practices in clinical studies.Clinical trials are not allowed. A clinical trial is defined in the Code of Federal Regulations, Title 45, Part 46.102 (45 CFR 46.102) as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include a placebo or another control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes.Studies that do not seek to measure safety, effectiveness, and/or efficacy outcome(s) of an intervention are not considered clinical trials.For the purposes of this funding opportunity, research that meets the definition of a clinical trial is distinct from clinical research. Clinical research encompasses research with human data, human specimens, and/or interaction with human subjects. Clinical research is observational in nature and includes:(1) Research conducted with human subjects and/or material of human origin such as data, specimens, and cognitive phenomena for which an investigator (or co-investigator) does not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention. Research meeting this definition may include but is not limited to: (a) mechanisms of human disease, (b) diagnostic or detection studies (e.g., biomarker or imaging), (c) health disparity studies, and (d) development of new technologies.(2) Epidemiologic and behavioral studies that do not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention.(3) Outcomes research and health services research that do not fit under the definition of clinical trial.Excluded from the definition of clinical research are in vitro studies that utilize human data or specimens that cannot be linked to a living individual and meet the requirements for exemption under 46.104(d)(4) of the Common Rule.The funding instrument for awards made under the program announcement will be grants (31 USC 6304).The anticipated direct costs budgeted for the entire period of performance for an FY24 PCRP Data Science Award should not exceed $1.0M. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.Awards supported with FY24 funds will be made no later than September 30, 2025.The CDMRP expects to allot approximately $11.2M to fund approximately seven Data Science Award applications. Funding of applications received is contingent upon the availability of federal funds for this program, the number of applications received, the quality and merit of the applications as evaluated by peer and programmatic review, and the requirements of the government. Funds to be obligated on any award resulting from this funding opportunity will be available for use for a limited time period based on the fiscal year of the funds. It is anticipated that awards made from this FY24 funding opportunity will be funded with FY24 funds, which will expire for use on September 30, 2030.

This grant provides funding to Baltimore City-based nonprofits for capital projects that promote heritage tourism, such as restoration and public murals, while requiring a matching contribution from non-city sources.

This program provides matching funds to local businesses, nonprofits, and government entities in Carbon County, Utah, to support economic development projects that improve infrastructure, workforce training, and facilities.

The Arizona Water Protection Fund (AWPF) is a competitive state grant program that provides funding to interested parties for the development and implementation of measures to protect water of sufficient quality and quantity to maintain, enhance, and restore river and riparian resources throughout Arizona (including projects that benefit fish and wildlife that are dependent on these important resources), and measures to increase water availability and supply. Financial Notes: Matching funds are not required to be eligible for AWPF funding; however, projects that do include matching funds typically receive higher consideration.   Administrative costs must be limited to a maximum of 5% of the total AWPF project funds requested.  Subcontractors or consultants working on your project must also conform to the 5% administrative cost limit if you are paying them out of AWPF funds.   Payments are made on a cost reimbursement basis.  Appropriate documentation (e.g., receipts, invoices, reports, data, and photographs) will be required in order to receive reimbursement.   Adequate accounting practices and record keeping will be required.

The DARPA Defense Sciences Office grant is aimed at fostering scientific discovery and innovation, anticipating future technological advancements, and understanding global changes to maintain a strategic advantage for the Department of Defense.

The Pennsylvania Department of Agriculture is inviting applications for agricultural research grants for projects to be conducted from July 1, 2024, to June 30, 2026. The projects should address various critical areas such as pest infestation impacts, Chesapeake Bay farm management practices, pollinator protection, food action plans, urban agriculture, energy in agriculture, animal health, and robotic technology in farming. Funding is contingent upon the 2024-2025 budget appropriations, and the deadline for application submission is June 7, 2024. The department will evaluate the proposals based on a 100-point scale considering project needs, research outcomes, methodology, evaluation and replicability, industry support, and research team diversity.

Amendment 1 (June 25, 2024): The purpose of this Amendment 1 is to: 1) make administrative updates to Section 1.1, 1.2, 2.1.2, 3.1, 3.2 and 5.2.6; 2) replace Section 2.1.1 with new language pertaining to Federally Funded Research and Development Centers (FFRDCs) and Government Entities. Additionally, Section 4.2, Evaluation Criteria #2 is updated to remove the reference to Government Entities (removal is not highlighted in yellow); 3) change references from Abstract to Solution Summaries (intent behind the document is unchanged); 4) update proposal submission instructions in Section 3.2; and 5) update Section 5.1 to remove the Stage 2 Notification Letter. All changes are highlighted in yellow.Also, please note that the title of this opportunity has bee revised to eliminate confusion. The opportunity should have been titled, "Master Announcement Instruction (MAI)" instead of "ARPA-H BDF Tool Box".The Master Announcement Instructions (MAI) is a new ARPA-H announcement that aims to create standard tiered proposal submission requirements, so the amount of work required to write a proposal is commensurate with the size of the proposed effort. It also aims to reduce the up-front work required to submit cost information to reduce the barrier to entry for non-traditional performers. Module announcements that link to this MAI will provide more specific instructions about how the proposal requirements vary across tiers of effort.All responsible sources capable of satisfying the Governments needs may submit a proposal to a Module Announcement. Specifically, universities, non-profit organizations, small businesses and other than small businesses are eligible and encouraged to propose to Module Announcements.NOTE: Proposals shall NOT be submitted against the MAI. Proposals shall only be submitted against a Module Announcement.

This funding opportunity supports nonprofit organizations and government entities in Chickasaw County to implement projects that enhance the community's quality of life across various sectors, including arts, education, health, and environment.

This grant provides $10,000 in reagent credits to researchers working on innovative stem cell and organoid projects at eligible institutions, helping to advance scientific breakthroughs in these fields.

This funding opportunity provides financial support to organizations that can enhance access, equity, and inclusion for individuals with disabilities in workforce development programs across California.

The DoD Reconstructive Transplant, Qualitative Research Validation and Implementation Award aims to fund further research and development of resources for the Vascularized Composite Allograft (VCA) community, which were initially created through RTRP-funded qualitative research studies, to enhance their readiness for clinical and community use, with a focus on improving patient outcomes and benefiting population health.

The Community Foundation of NCW's New Legacy Funds Grant Program represents a strategic shift towards place-based, community-centered grant distribution, replacing the Regional Impact Grant as the primary source of funding for nonprofits across North Central Washington. This initiative aligns with the foundation's mission to address community needs through a localized approach, leveraging the insights of local advisory boards (LABs) to guide the grant-making process. The program emphasizes direct community involvement, ensuring that funding decisions are informed by those who best understand their community's critical needs and enrichment opportunities. The target beneficiaries of the Legacy Fund Grants are nonprofits operating within specific geographic regions: Cashmere, Chelan Valley, Methow Valley, Okanogan Valley, Upper Valley, and Wenatchee Valley. The program aims to provide unrestricted funding, empowering these organizations to effectively meet community needs within their respective areas. The impact goal is to foster meaningful community development and address a diverse range of local challenges, reflecting the philanthropic legacies of individuals and families who established these funds. The program's priorities and focus areas are comprehensive, encompassing Arts, Culture, Humanities; Community Service/Social Benefit; Environmental/Animal Protection; Health and Human Services; and Youth Development. This broad scope allows the foundation to support a wide array of initiatives that contribute to the overall well-being and vitality of the communities in North Central Washington. The emphasis on unrestricted funding underscores the foundation's trust in local nonprofits to allocate resources where they are most needed and effective. While specific measurable results are not detailed in the provided information, the program's structure suggests an expected outcome of strengthened local charitable organizations and enhanced capacity to address community needs. The foundation's strategic priority is to integrate more community members into the grant-making process, thereby creating a more responsive and effective funding mechanism. The underlying theory of change appears to be that by empowering local advisory boards and providing flexible funding to geographically targeted nonprofits, the foundation can achieve more impactful and sustainable community development outcomes.

The U.S. Department of State announces an open competition for organizations to submit applications to facilitate the launch of the Marine and Blue Economy Hackathon. Please follow all instructions in the "Marine and Blue Economy Hackathon NOFO Full Instructions" document under the Related Documents tab. Priority Region: Lagos, Nigeria Overview and Purpose Inadequate technological solutions and lack of coordination across Nigerias marine and blue economy-related sectors have led to untapped economic opportunities, unsustainable fishing practices, plastic pollution, and environmental damage. To implement the Partnership for Atlantic Cooperation Plan of Action and to bolster U.S.-Nigeria relations, a selected implementing partner, in consultation with the U.S. Mission Nigeria, will launch the Marine and Blue Economy Hackathon. This two- to three-day event will bring together approximately 60 working-level government officials, private sector experts, academics, entrepreneurs, and students to crowdsource innovative technical solutions to marine and blue economy-related problems. Defining Problem Statements, Crowdsourcing Solutions, and Measuring Results The selected implementing partner, in consultation with the U.S. Mission in Nigeria, will define three marine and blue economy-focused problem statements. Problem statements should reflect local needs and the priorities established by the Partnership for Atlantic Cooperation member countries including sustainable fisheries management, plastic pollution prevention, coastal community resilience, marine conservation, sustainable aquaculture management, ghost gear solutions, aquatic food technology advancement, ocean data and information gathering and analysis, and marine spatial planning implementation. During the hackathon, participants will: (a) translate multifaceted problems into succinct technical specifications and statements recognizable to software and technology designers; and (b) form teams to generate actionable and innovative technical solutions to the shared problem statement(s). At the end of the hackathon, a winner will be selected by a board of American and Nigerian judges for the most innovative and impactful solution developed, and a prize will be offered. After the hackathon, participants will then deploy the solutions they collaboratively design, leverage partnerships established with their counterparts across the sector, and closely coordinate with one another to ensure the solutions address the identified problems. Hackathon results can be measured by number and quality of targeted small-group sessions, the introduction of new tools and technologies, and creation of prototypes that address the problems hackathon participants tackle. In order to be considered, implementing partner applicants must demonstrate a clear commitment to inclusive participation. The selected implementing partner must reach out to potential participants from marginalized populations and communities, ensure balance among hackathon participants, and provide accessibility accommodations as needed. Participants and Audiences This two- to three-day event will bring together approximately 60 working-level government officials, private sector experts, academics, entrepreneurs, and students to crowdsource innovative technical solutions to marine and blue economy-related problems.

This grant provides financial and volunteer support to nonprofit organizations in the Sacramento area that focus on youth development and promote diversity, equity, and community empowerment.

This funding opportunity provides financial support for the construction, maintenance, and improvement of trails and shared-use paths throughout Montana, benefiting local communities and outdoor enthusiasts.

The intent of the FY24 LCRP Concept Award is to support innovative, non-incremental, high-risk/potentially high-reward research that will provide new insights, paradigms, technologies, or applications in lung cancer. Studies supported by this award are expected to lay the groundwork for future avenues of scientific investigation. The proposed research project should include a well-formulated, testable hypothesis based on a sound scientific rationale and study design. Research applications only in the area of mesothelioma will not be accepted.Inclusion of preliminary data is not required but is allowed. The strength of the proposed research should be based on sound scientific rationale and logical reasoning. The presentation of substantial preliminary data suggests that the proposed research project would be more appropriately submitted to a different FY24 LCRP funding opportunity. The outcome of research supported by this award should be the generation of robust preliminary data that can be used as a foundation for future research projects. Absence of preliminary data will not negatively affect scientific or programmatic review of the application.Care Delivery and Health Disparity Option: The FY24 LCRP Concept Award mechanism encourages applications that specifically address the comprehensive lung cancer care and/or health disparities FY24 LCRP Areas of Emphasis by offering a Care Delivery and Health Disparity option. Applications from the Care Delivery and Health Disparity option will be peer and programmatically reviewed separately from applications submitted to the Cancer Research Continuum option.Relevance to Military Health: The LCRP seeks to support research that is relevant to the healthcare needs of military Service Members, Veterans, and their Families. Relevance to military health will be considered in determining relevance to the mission of the Defense Health Program (DHP) and FY24 LCRP during programmatic review. Investigators are strongly encouraged to consider the following characteristics as examples of how a project may demonstrate relevance to military health:Use of military or Veteran populations, biospecimens, data/databases, or programs in the proposed research Collaboration with Department of Defense (DOD) or Department of Veterans Affairs (VA) investigatorsExplanation of how the project addresses an aspect of lung cancer that has relevance or is unique to the military, Veterans, other Military Health System (MHS) beneficiaries, or Family readiness of Service Members, including environmental exposures other than tobacco.All investigators applying to FY24 LCRP funding opportunities are encouraged to consider leveraging resources from the LCRP-funded Lung Cancer Biospecimen Resource Network (LCBRN) if retrospectively collected human anatomical substances and correlated clinical data are relevant to the proposed studies. Samples from the LCBRN are currently available through the Cooperative Human Tissue Network (CHTN). To request LCBRN samples, contact the Division Coordinator for the CHTN Mid-Atlantic division (email: [email protected]) located at the University of Virginia.A congressionally mandated Metastatic Cancer Task Force was formed with the purpose of identifying ways to help accelerate clinical and translational research aimed at extending the lives of advanced state and recurrent patients. As a member of the Metastatic Cancer Task Force, the CDMRP encourages applicants to review the recommendations (https://health.mil/Reference-Center/Congressional-Testimonies/2018/05/03/Metastatic-Cancer-Research) and submit research ideas to address these recommendations provided they are within the limitations of this funding opportunity and fit within the FY24 LCRP priorities.Applications from investigators within the military services and applications involving multidisciplinary collaborations among academia, industry, the military services, the VA, and other federal government agencies are highly encouraged. These relationships can leverage knowledge, infrastructure, and access to unique clinical populations that the collaborators bring to the research effort, ultimately advancing research that is of significance to Service Members, Veterans, and/or their Families. If the proposed research relies on access to unique resources or databases, the application must describe the access at the time of submission and include a plan for maintaining access as needed throughout the proposed research.

The FY24 ARP Idea Development Award supports the development of innovative, high-risk/high-reward research that could lead to critical discoveries or major advancements that will accelerate progress in improving outcomes for Autistic individuals. Applications are strongly encouraged to address one of the FY24 ARP Idea Development Award Areas of Interest or provide justification that the proposed research addresses a critical problem, question, or need in ASD. This award mechanism is designed to support innovative ideas with the potential to yield impactful data and new avenues of investigation.Research funded by the FY24 ARP should be responsive to the needs of people with ASD, their families, and/or caregivers. Researchers are therefore encouraged to establish and utilize effective collaborations and partnerships with community members to maximize the translational and impact potential of the proposed research.CDMRP encourages research on health areas and conditions that affect women uniquely, disproportionately, or differently from men, including studies analyzing sex as a biological variable. Such research should relate anticipated project findings to improvements in womens health outcomes and/or advancing knowledge for womens health.

Youth Service America's (YSA) "We Serve to Remember 9/11 Day of Service Grants" program is designed to empower young changemakers aged 5 to 25. This initiative directly aligns with YSA's mission of engaging youth in service and fostering active citizenship. The grants support organizations, schools, and youth changemakers in planning and implementing service activities that honor and pay tribute to those affected by 9/11. The program emphasizes youth leadership, ensuring that projects are driven by the young participants themselves, thereby developing their leadership skills and sense of community responsibility. The program's target beneficiaries are primarily youth, with a strong focus on engaging those who are not typically asked to serve and face systemic barriers to participation. This includes young people of color, youth from underserved low-income families and neighborhoods, and youth who are often beneficiaries of service rather than participants. Specific groups identified include youth in rural communities, those experiencing homelessness, youth in foster care, youth with disabilities, youth in the juvenile justice system, immigrants or refugees, youth from military families, LGBTQ+ youth, and English language learners. The impact goal is to create a more inclusive service environment and empower a diverse group of young people to contribute to their communities. A key priority of this grant program is the engagement of at least 100 youth volunteers per project, with 80% of these volunteers identifying as youth facing systemic barriers to participation. Projects must include elements to honor and pay tribute to those who lost their lives on 9/11, their families, and those who responded in service. All activities must take place on or around September 11th National Day of Service and Remembrance (September 11, 2024). This specific timing reinforces the program's focus on remembrance and national service. YSA expects to award up to 100 grants of $1,000 each. The expected outcomes include a significant increase in youth engagement in service, particularly among marginalized groups, and the successful execution of service activities that commemorate 9/11. Measurable results will include the number of grants awarded, the number of youth volunteers engaged, and the percentage of those volunteers who identify as facing systemic barriers. The program also aims to foster a sense of civic duty and historical awareness among participants. The foundation's strategic priorities are centered on youth empowerment and inclusive participation in service. YSA's theory of change posits that by providing resources and opportunities, particularly to underserved youth, they can develop leadership skills, strengthen communities, and create a lasting impact. By focusing on youth-led projects and ensuring diverse representation, YSA aims to build a generation of civically engaged individuals who are committed to addressing community needs and remembering significant historical events. Applicants must be based in the United States, with activities benefiting people in the U.S., including its territories. This geographical focus ensures that the grants support local communities across the nation. The emphasis on reaching youth who face systemic barriers aligns with a broader strategic goal of promoting equity and inclusion within the service sector, demonstrating YSA's commitment to a more representative and impactful youth service movement.

This program provides $50,000 grants to small nonprofit arts organizations in select states to strengthen their operational sustainability and enhance their community services.

The Ackley Community Foundation, an affiliate of the Community Foundation of Northeast Iowa, is offering grants to support charitable capital projects, activities, services, programs, and organizations. The core mission of this grant program is to enhance the quality of life for residents of Ackley, Iowa, aligning with the Foundation's broader goal of fostering a community where people desire to live, work, play, and stay. This strategic focus ensures that all funded initiatives contribute directly to the betterment of the local community. The primary beneficiaries of these grants are the people of Ackley, Iowa. The program aims to create a positive and lasting impact across various sectors, including Art and Culture, Community Betterment, Education & Youth Development, Environment and Animal Welfare, Health, and Human Services. The overarching goal is to address community-based needs and improve the overall well-being and vibrancy of Ackley. Funding priorities emphasize requests that demonstrate a clear community need, broad community support, and benefits for the entire community. High priority is also given to organizations that can leverage funding and support from other sources, showcasing matching funds in their budgets. Furthermore, the Foundation values initiatives that maximize community resources through cooperation and collaboration with other local organizations, avoiding service duplication. The capacity of the organization and its staff to achieve desired results, as well as the long-term sustainability of the project without continuous financial reliance on the Ackley Community Foundation, are also critical considerations. Expected outcomes include tangible improvements in the quality of life for Ackley residents, such as enhanced cultural opportunities, stronger community bonds, improved educational outcomes for youth, better environmental stewardship, and increased access to health and human services. The Foundation's theory of change posits that by strategically investing in these key areas, it can catalyze positive social and economic development, leading to a more attractive and thriving community for all its inhabitants. The minimum request amount is $500, with most grants ranging from $500 to $3,000, ensuring a broad range of projects can be supported.