Grants for Small businesses - Science and Technology

This funding opportunity supports researchers and institutions conducting fundamental scientific research across various fields to advance the U.S. Air Force and Space Force's technological capabilities.

The Rural and Municipal Utility Cybersecurity (RMUC) Program is offering a grant opportunity for electric cooperative, municipal, and small investor-owned utilities with limited cybersecurity resources. The Advanced Cybersecurity Technology (ACT) 1 Prize is a three-phase competition that challenges eligible utilities to identify risks and implement solutions to improve their overall cybersecurity posture. Utilities that progress through the competition will receive cash prizes and technical assistance to invest in staff training, governance processes, and cybersecurity tools and technologies. To apply, interested applicants should review the official rules for the complete application process and requirements. Eligible utilities can then create a HeroX account, accept the ACT 1 Prize Competitor Agreement, and choose whether to compete as a team. Application templates are available to aid in completing the application. Additionally, Phase 1 applicants must participate in two mandatory virtual webinars. The ACT 1 Prize offers a total prize pool of up to $8.96 million in cash and technical assistance across three phases: Commitment, Planning, and Implementation. Each phase concludes with a prize award. In the Commitment Phase, utilities prepare submission packages describing their resources, need for improving cybersecurity, and commitment to participating. In the Planning Phase, utilities work with technical assistance providers to assess systems, identify training needs, understand risks and solutions, and draft an implementation roadmap. Finally, in the Implementation Phase, utilities make progress towards completing their roadmap with the help of technical assistance providers. Administered by DOE's National Renewable Energy Laboratory (NREL) and managed by DOE's Office of Cybersecurity, Energy Security, and Emergency Response (CESER), the RMUC Program's ACT 1 Prize is part of a larger initiative to enhance the cybersecurity posture of electric utilities. The program will provide $250 million over five years to support critical investments, deliver technical assistance, and provide cybersecurity training to utility workers. This will result in a more secure and resilient energy grid. Interested parties can visit the RMUC Program webpage for more information and to sign up for updates.

The Chesapeake Oyster Innovation Award Program, offered by the Chesapeake Bay Trust and supported by the Chesapeake Bay Foundation, aims to increase knowledge of the value of oysters, advance technologies for increasing oyster populations or aquaculture production, and improve oyster population monitoring techniques. This program supports projects in Maryland and Virginia and welcomes requests from members of the Chesapeake Oyster Alliance, including community organizations and both for-profit and nonprofit organizations. The grant awards up to $10,000, with applications due by September 19, 2024. Match is encouraged but not required.

This funding opportunity supports research into innovative energy generation and storage technologies for military and commercial applications, focusing on their reliability and integration into electrified systems.

This funding opportunity supports U.S. institutions conducting clinical trials on innovative regenerative medicine therapies using adult stem cells, focusing on extending research from previously funded projects.

Supports the construction, purchase, expansion, or upgrade of workforce or training-related infrastructure to better meet the needs of the offshore wind industry.

This grant provides funding for research institutions and companies to develop innovative tactics and technologies for small groups of autonomous systems to effectively maneuver in complex military environments.

This funding opportunity supports Arizona-based institutions conducting clinical research on ibogaine to treat neurological diseases, aiming to advance health and wellness for residents through innovative, collaborative projects.

The Downtown Development Authority (DDA) of Lawrenceville, Georgia, has launched the Façade Grant Program to revitalize its downtown area. This program aligns with the DDA's mission to serve as a resource to the City Council for downtown revitalization through strategic land use planning, land banking, business recruitment and retention, and the execution of the community's vision for a vibrant and inclusive urban center. The grant specifically targets businesses within the Downtown Entertainment District, aiming to encourage and support exterior renovations that enhance the aesthetic appeal and overall vitality of the area. The primary beneficiaries of this program are businesses located within the Downtown Entertainment District. The impact goals are centered on improving the physical appearance of downtown buildings, stimulating economic activity, and fostering a more attractive and inclusive urban environment. By offering reimbursement for façade renovations, the DDA seeks to reduce the financial burden on businesses, thereby encouraging investment in property improvements and contributing to a more appealing downtown. The program prioritizes projects that enhance or update the exterior of buildings, including activities such as painting, restoration, stabilization, awning additions, and improved signage. Eligibility criteria dictate that projects must be within the Downtown Entertainment District, and reimbursement is solely for expenses incurred during exterior façade renovations. Furthermore, all projects must comply with applicable building, development, and zoning regulations, and properties on the National Historic Register require a preservation review. Expected outcomes include a visibly improved and more attractive downtown area, increased business investment in property aesthetics, and a boost in overall community pride and engagement. Measurable results for the program include the number of businesses participating, the total amount of grant funds disbursed, the types of renovations undertaken, and the completion of approved work within the stipulated twelve-month timeframe. The reimbursement structure, covering half of the total project cost up to $2,500 per grant, provides a tangible incentive for businesses to participate.

This funding opportunity supports projects that develop and operate geologic field laboratories for carbon storage technology, targeting organizations with access to suitable sites for testing and advancing carbon capture solutions.

This funding opportunity provides financial support to U.S.-based small businesses for innovative research and development projects that address critical challenges in energy, environment, and national security.

This grant supports entrepreneurs and researchers in Pennsylvania by providing resources and funding to help turn innovative ideas into marketable products and services that benefit the community and beyond.

The FY24 OCRP Clinical Trial Translational Endpoints Research Award intends to support correlation of clinical trial-related data (e.g., biosample analysis, imaging, or epidemiological data) with clinical outcomes or responses to therapies. Correlative studies may be associated with a past, ongoing, or future clinical trial in order to associate various factors (genetic, DOD FY24 Ovarian Cancer Clinical Trial Translational Endpoints Research Award 4biochemical, environmental and others) with initiation, progression, metastasis, recurrence, prognosis, diagnosis or effect of intervention on ovarian cancer outcomes. The translational research should address high-impact or unmet needs in ovarian cancer. The proposed research may be hypothesis testing or may be designed to generate new hypotheses to be tested in follow-up clinical research. The award may not be used to directly support a clinical trial.

The Nebraska SBIR/STTR Initiative provides financial assistance to small businesses in Nebraska participating in the federal SBIR/STTR programs. This state initiative offers Phase 0 assistance to help businesses apply for federal Phase 1 funding and matching funds for successful Phase 1 and Phase 2 federal awards. The initiative aims to promote innovation and technology transfer among small businesses in Nebraska, with a total fund availability of up to $6 million per year. Grant renewed every year. Grant Annual opening/closing deadline: July 1st to June 30th

This program provides financial assistance to businesses in Wabasha for improving the exterior of their commercial or industrial buildings, promoting revitalization and private investment in the community.

The DoD Kidney Cancer, Clinical Trial Award is a funding opportunity aimed at supporting the implementation of clinical trials that have the potential to significantly impact the treatment or management of kidney cancer, with a focus on new products, pharmacologic agents, devices, clinical guidance, and emerging approaches and technologies.

The Heartland Regional Food Business Center is offering Business Builder Subawards ranging from $5,000 to $50,000 to support small food and farm businesses in selected states and counties, aiming to expand local and regional food markets, increase business acumen, and strengthen food systems in response to COVID-19, with projects to be completed within a year.

This ISO seeks solution summary and proposal submissions for projects that fall within the scope of the ARPA-H mission Resilient Systems Office (RSO). RSOs interest areas will address systemic challenges across the healthcare and public health landscape by investing in cutting-edge technologies that address long-standing gaps in the quality, efficacy, and consistent availability of care.Aspects of todays health and public health systems remain fragile due to systemic challenges, which include rising healthcare costs, inadequate healthcare coverage for significant populations, outdated infrastructure, and health disparities among different demographic groups. Acute challenges, such as hospital closures, supply chain disruptions, staffing shortages, cyber-attacks, public health crises, and the emergence of new diseases, further exacerbate existing fragilities, making it more difficult to maintain high standards of care. These challenges are compounded by the fact that systems remain fragmented, hindering the ability to gain comprehensive insights, make informed decisions, develop tailored interventions, and share critical health information between stakeholders.RSO seeks solution summaries and proposals that drive innovations to enhance the adaptability, reliability, and interoperability of the health ecosystem. Of interest are innovations that foster flexibility and enable adaptation to system stressors, so that people and systems remain well-positioned to deliver high-quality care and improve health outcomes. The following interest areas categorize the ground-breaking research we seek to support:Sociotechnical System Innovation: Innovate user-centric digital health tools, platforms, technologies, and intervention models that improve outcomes across the health continuum, including prevention, diagnosis, and treatment of physical, mental, and behavioral health. Approaches to build trust in the healthcare system and distribute high-quality health guidance in an understandable manner that improves patient outcomes. Novel real-time measurement tools to track health outcomes, evaluate post-market performance of new interventions, and enable convergence on the most effective strategies to improve the quality of care, especially for underserved communities. Other population centered innovations to create more resilient communities and subpopulations. Innovations might include aggregate improvements to quality of care and better physical, mental, and behavioral health outcomes for the health ecosystem.Health Ecosystem Integration: Novel ways to collect, protect, secure, integrate, analyze, communicate, and present health data, including but not limited to advances in privacy, cyber security, artificial intelligence with enhanced patient safety properties, low-code or no-code technologies, semantic approaches, and rapid integration techniques. Strategies and technologies to leverage homes, community centers, pharmacies, and other accessible locations to enable new modalities of high-quality care, expand the reach of clinical research, or integrate end-user feedback to rapidly iterate prototype designs. Approaches to strengthen the connectivity and interoperability of health data and devices to 5 enable the safe, secure, and seamless exchange of information among healthcare providers, researchers, and stakeholders. Other novel approaches to increase the interoperability of health-related systems in support of improved health outcomes and enhanced transparency across the health ecosystem.Adaptive Antifragile Solutions: Creative approaches to enhance the stability and dependability of the health ecosystem through new adaptive paradigms, methods that anticipate and mitigate disruptions before they occur, and enhancements to emergency response. Approaches that enable health infrastructure to rapidly integrate information from new sensors; create decision support tools; adapt supply chains, manufacturing, and logistics; and better leverage the workforce during public health emergencies. Novel methods to engineer resilient tissues, microbiomes, and biophysical systems to combat disease or maintain health. Other novel approaches to enhance adaptability and reduce fragility within the health ecosystem.Proposals are expected to use innovative approaches to enable revolutionary advances in science, technology, systems, or methodology. Specifically excluded are proposals that represent an evolutionary or incremental advance in the state of the art or technology that has reached the clinical trial stage. Additionally, proposals directed towards policy changes, traditional education and training, or center coordination, formation, or development, and construction of physical infrastructure are outside the scope of the ARPA-H mission

This funding opportunity provides financial support for innovative breast cancer research projects aimed at preventing the disease, understanding its recurrence, or improving treatment, targeting both early-stage and more developed studies from a range of eligible organizations and researchers.

**AMENDED on DECEMBER 11 2023**: The latest revision is posted as Amendment 18. Potential applicants are strongly encouraged to review the Amendment in its entirety, as it updates several sections. Specifically, ATTACHMENT 1: SPECIFIC TOPICS now includes Basic Research Topics N1-N4, with white papers due by 11:59pm EST on 5 February 2024. White papers may not be considered if they are received after this deadline. In addition, submissions to the general thrust areas in accordance with the requirements detailed in the BAA are also welcome. ** Please note that all correspondence must be sent to the appropriate Agency contact identified in Section 7. Agency Contacts. **