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Grants for Nonprofits - Federal

Explore 5,497 grant opportunities

Long Range Broad Agency Announcement (LRBAA) 24-01
Contact for amount
U.S. Department of Homeland Security (DHS), Science and Technology Directorate (S&T)
Federal
Rolling

Application Deadline

May 31, 2029

Date Added

Mar 18, 2025

This grant invites industry and academic researchers to propose innovative solutions that enhance homeland security across various mission areas, including counterterrorism, cybersecurity, and public safety.

Science and Technology
For profit organizations other than small businesses
ROSES25: A.3 NASA ISRO Synthetic Aperture Radar Mission Data, Applications, Research, and Technology Team
Contact for amount
National Aeronautics and Space Administration (NASA Headquarters)
Federal

Application Deadline

May 14, 2026

Date Added

Feb 13, 2026

This grant provides funding for U.S.-based research institutions to develop applications and technologies using advanced radar data from a collaborative NASA and ISRO mission, focusing on monitoring Earth's land and ice changes.

Science and Technology
Public and State controlled institutions of higher education
Methodology, Measurement, and Statistics
$3,760,000
National Science Foundation
Federal

Application Deadline

Aug 27, 2026

Date Added

Feb 7, 2025

This program provides funding for innovative research in statistical methods and data collection techniques that benefit social, behavioral, and economic research, particularly through collaboration with federal statistical agencies.

Information and Statistics
Public and State controlled institutions of higher education
Findable Accessible Interoperable Reusable Open Science
$600,000
National Science Foundation
Federal

Application Deadline

Apr 8, 2026

Date Added

Apr 17, 2025

This program provides funding to U.S.-based organizations for projects that improve research data management and promote open science practices across various scientific disciplines.

Science and Technology
Public and State controlled institutions of higher education
ROSES 2025: D.5 Astrophysics Pioneers
Contact for amount
National Aeronautics & Space Administration (NASA Headquarters)
Federal

Application Deadline

Apr 2, 2026

Date Added

Jul 15, 2025

This funding opportunity supports innovative research projects in astrophysics from U.S.-based organizations, encouraging collaboration and scientific advancement in space science and technology.

Science and Technology
Public and State controlled institutions of higher education
Reissue of RFA-FD-23-001- Clinical Studies of Orphan Products Addressing Unmet Needs of Rare Diseases (R01 Clinical Trials Required)
$900,000
U.S. Department of Health & Human Services (Food and Drug Administration)
Federal

Application Deadline

May 16, 2028

Date Added

Jul 12, 2025

This funding opportunity provides financial support for clinical trials aimed at developing new treatments for rare diseases affecting fewer than 200,000 people in the U.S., encouraging innovative trial designs and collaboration among various research entities.

Health
Public and State controlled institutions of higher education
ROSES 2025: Research Opportunities in Space and Earth Science
$5,000,000
National Aeronautics and Space Administration (NASA Headquarters)
Federal

Application Deadline

May 31, 2026

Date Added

Jul 12, 2025

This funding opportunity supports a wide range of research and technology development in Earth and space sciences, aimed at U.S.-based institutions, nonprofits, private entities, and government organizations, to advance NASA's strategic mission goals.

Science and Technology
Public and State controlled institutions of higher education
Glioblastoma Therapeutics Network (GTN; U19 Clinical Trial Required)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

May 27, 2026

Date Added

Sep 18, 2025

This funding opportunity supports diverse research teams in developing innovative therapies for adult glioblastoma, focusing on translating promising treatments into early clinical trials.

Health
State governments
National Cancer Institute Program Project Applications for the Years 2023, 2024, and 2025 (P01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

May 25, 2026

Date Added

Dec 14, 2022

This funding opportunity supports collaborative cancer research projects that integrate multiple disciplines and require at least three interconnected research initiatives, aimed at advancing knowledge in cancer biology, prevention, diagnosis, treatment, or control.

Education
Independent school districts
Translational Neural Devices (R61/R33 - Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 28, 2027

Date Added

Oct 31, 2024

This funding opportunity supports the development and clinical testing of innovative neural devices designed to treat nervous system or neuromuscular disorders, encouraging diverse participation and collaboration among various institutions and organizations.

Health
State governments
Disability and Rehabilitation Engineering
$5,000,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Jan 3, 2025

This program provides funding for innovative engineering research that improves the quality of life for individuals with disabilities by developing new technologies and methodologies to enhance their functional abilities and interactions with their environments.

Science and Technology
Nonprofits
Leveraging Network Infrastructure to Conduct Innovative Research for Women, Children, Pregnant and Lactating Women, and Persons with Disabilities (UG3/UH3 - Clinical Trial Optional)
$6,250,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 15, 2027

Date Added

Dec 17, 2024

This funding opportunity provides financial support for innovative research projects focused on improving health outcomes for women, children, pregnant and lactating women, and individuals with disabilities through multisite clinical trials and observational studies.

Health
Public and State controlled institutions of higher education
Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R21 Clinical Trials Not Allowed) - PAR-25-096
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 7, 2026

Date Added

Nov 19, 2024

This grant provides funding for researchers to analyze and integrate existing cancer-related data to improve understanding of cancer risk, prevention, and outcomes, particularly in underrepresented populations.

Education
State governments
Environmental Engineering
$10,000,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Jun 2, 2025

This funding opportunity supports innovative research projects that aim to reduce pollution and improve environmental and human health through interdisciplinary approaches in environmental engineering.

Science and Technology
Nonprofits
Dynamics, Control and Systems Diagnostics
Contact for amount
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Mar 30, 2022

This funding opportunity supports researchers in engineering and related fields to explore and improve the behavior, diagnostics, and control of dynamic systems through innovative theoretical, computational, or experimental approaches.

Science and Technology
Public and State controlled institutions of higher education
Puget Sound Action Agenda - Strategic Implementation Leads
$48,000,000
U.S. Environmental Protection Agency
Federal

Application Deadline

May 11, 2026

Date Added

Mar 12, 2026

This funding opportunity provides financial support to Washington State and local governments, Tribes, nonprofits, and educational institutions for projects focused on protecting and restoring the Puget Sound ecosystem in areas such as habitat, shellfish, and stormwater management.

Environment
State governments
Topology
Contact for amount
National Science Foundation
Federal

Application Deadline

Nov 3, 2026

Date Added

Nov 21, 2024

This funding opportunity supports researchers and institutions in the U.S. working on fundamental and applied studies in topology, including areas like algebraic topology, knot theory, and topological data analysis.

Science and Technology
Individuals
ROSS Rapid Response Program
$250,000
U.S. Department of Housing and Urban Development
Federal

Application Deadline

Jan 25, 2027

Date Added

Jan 27, 2026

This program provides financial support to various community organizations and housing authorities to quickly address urgent needs and emergencies affecting residents of HUD-assisted housing.

Community Development
Native American tribal organizations
Operations Engineering
Contact for amount
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Jun 12, 2018

This program provides funding for research that develops advanced analytical methods to improve decision-making and operations in various sectors, including manufacturing, public safety, healthcare, and environmental sustainability.

Science and Technology
Public and State controlled institutions of higher education
Life and Environments Through Time
$14,000,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Dec 9, 2024

This grant provides funding for research that explores the evolution of Earth's climate, environments, and life, aimed at institutions and organizations engaged in educational or scientific activities.

Science and Technology
Nonprofits