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Grants for Nonprofits - Federal

Explore 5,534 grant opportunities

Resource-Related Research Projects for Development of Animal Models and Related Materials (R24 Clinical Trials Not-Allowed)
$5,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 25, 2025

Date Added

May 22, 2025

This funding opportunity supports the development and enhancement of animal models and related biological tools that are broadly applicable to various areas of biomedical research, aimed at improving our understanding of human diseases and advancing therapeutic interventions.

Health
State governments
Microglial Pathophysiology in Comorbid Substance Use Disorder (SUD) and HIV (R61/R33 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 25, 2024

Date Added

Jul 19, 2023

This grant provides funding for researchers to explore how HIV and substance use disorders affect protein interactions in microglia, aiming to uncover mechanisms that could lead to new treatments for these interconnected conditions.

Education
State governments
NIH SIREN Neurologic Clinical Trials (UG3/UH3 - Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 7, 2024

Date Added

Feb 8, 2023

This funding opportunity announcement (FOA) encourages applications for multi-center clinical trials focused on neurological emergencies. Successful applicants will collaborate and conduct the trial within the NIH SIREN Network. The NIH SIREN Clinical Coordinating Center (CCC) will work with the successful applicants to implement the proposed trial efficiently and the SIREN Data Coordinating Center (DCC) will provide statistical and data management support. The NIH SIREN hubs and their affiliated clinical sites will provide on-site implementation of the clinical protocols.The NIH SIREN Network will also be uniquely poised to collaborate with other US and international consortia necessary to conduct larger, definitive trials of promising interventions for neurological emergencies.Multi-center clinical trials in stroke treatment, recovery, or prevention supported by NINDS will be conducted in the NIH StrokeNet, and not within SIREN. Applicants do not need to be part of the existing SIREN infrastructure to apply under this FOA.

Health
State governments
Disseminating PCOR Evidence for Long COVID Care into Practice Through Up-to-Date Clinical Decision Support
Contact for amount
U.S. Department of Health & Human Services (Agency for Health Care Research and Quality)
Federal

Application Deadline

Mar 19, 2025

Date Added

Jan 13, 2025

This funding opportunity provides financial support to healthcare organizations and educational institutions for developing clinical decision support systems that integrate the latest research on Long COVID care, with a focus on improving patient outcomes and equity in underserved populations.

Health
State governments
Quantum Sensing of Neutrinos (QuSeN)
$5,000,000
U.S. Department of Defense (DARPA - Defense Sciences Office)
Federal

Application Deadline

Feb 3, 2025

Date Added

Nov 6, 2024

This grant provides funding for organizations to develop advanced neutrino detectors using quantum sensing technologies, targeting improved detection capabilities for neutrinos from various sources, including nuclear reactors.

Science and Technology
State governments
Strengthening Community Resilience and Policing in Uzbekistan
$300,000
U.S. Department of State - Bureau of International Narcotics-Law Enforcement
Federal

Application Deadline

Aug 5, 2024

Date Added

Jun 11, 2024

The Bureau of International Narcotics and Law Enforcement Affairs of the U.S. Department of State announces an open competition for organizations to submit applications to carry out a project to strengthen community policing practices in Uzbekistan. The Government of Uzbekistan has continued its broad reform efforts that began in earnest in 2017, including efforts to modernize the countrys security services. Despite reforms, public trust in security forces remains low, and allegations of corruption, unresponsiveness, and abuse persist. Civil society, which plays an important role in mobilizing citizenry to advocate for better community conditions, remains fragmented and generally lacks support and social capital to push for systemic change. This project will both strengthen Uzbek civil society organizations as they engage in community-based advocacy while also helping local government actors, especially the Ministry of Internal Affairs, develop protocols and procedures to be more transparent, responsive, and communicative in their relations with local communities. Goals of the project Enhance Civil Society Capacity for Community-Based Advocacy Strengthen Government Accountability and Transparency in Local Communities Foster Collaboration and Partnership Between Civil Society and Government Actors

Community Development
Nonprofits
DoD, Melanoma, Idea Award
$400,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Aug 26, 2024

Date Added

May 9, 2024

The FY24 MRP Idea Award supports innovative, untested, exploratory, high-risk/potentially high-reward concepts, theories, paradigms, and/or methods that address at least one of the FY24 MRP Focus Areas in Section II.A.1. Key aspects of the Idea Award: The intent of the Idea Award is to generate novel research avenues for investigation; therefore, novelty and innovation should be key aspects of the proposed research. Research supported by the Idea Award must introduce a new paradigm, challenge existing paradigms, look at existing problems from new perspectives, or exhibit other highly creative qualities. The proposed project must be exploratory, hypothesis-driven, or hypothesis-generating research and be based on a well-developed study design and plan of analysis. Principal Investigators (PIs) new to the melanoma field are encouraged to apply. The Idea Award is NOT intended to expand or extend previously published findings or continue a line of research already established and /or funded in the PIs laboratory. Incremental advances, the next logical step, or merely switching the object or method of inquiry from one cancer to melanoma is not considered innovative. The expected outcome of research supported by this award is the generation of robust preliminary data to be used as a foundation for future melanoma-focused research projects. Inclusion of preliminary data is discouraged. PIs proposing projects already supported by significant preliminary data and/or other funding sources should consider applying to other FY24 MRP funding opportunities for which the inclusion of preliminary data is more appropriate or required. Inclusion of preliminary data other than serendipitous findings is not consistent with the exploratory/innovative nature of this award. If preliminary data are included, they should be unanticipated outcomes or results from an unrelated project or study.

Science and Technology
Nonprofits
FY2025 - Historic Preservation Fund- Annual State Historic Preservation Office Grants
$2,200,000
U.S. Department of the Interior (National Park Service)
Federal

Application Deadline

Sep 15, 2025

Date Added

Jul 2, 2025

This program provides annual matching funds to state and territorial historic preservation offices to support the preservation and recognition of historic properties across the United States.

Humanities
State governments
Revision Applications for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (R01 Clinical Trial Optional)
$150,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 3, 2025

Date Added

Jan 2, 2025

This funding opportunity is designed for researchers with existing NCI R01 grants to integrate innovative cancer research technologies into their projects, enhancing the study's impact and advancing the field of cancer research.

Education
State governments
DOI - HQ Experienced Services Program
$500,000
U.S. Department of the Interior (Interior Business Ceter)
Federal

Application Deadline

Dec 2, 2024

Date Added

Nov 1, 2024

This funding opportunity provides financial support to nonprofit organizations that recruit and employ skilled workers aged 55 and older for various projects within the Department of the Interior, enhancing operational capacity in areas like infrastructure and environmental programs.

Employment Labor and Training
Nonprofits
Research on Autism Spectrum Disorders (R21 Clinical Trial Optional)
$200,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 16, 2024

Date Added

Apr 30, 2024

This funding opportunity supports innovative research projects aimed at understanding and improving the diagnosis, treatment, and services for individuals with Autism Spectrum Disorders, welcoming applications from a diverse range of organizations, including universities and nonprofits.

Environment
State governments
Great Lakes Fish Monitoring and Surveillance Program
$1,200,000
Environmental Protection Agency (Environmental Protection Agency)
Federal

Application Deadline

Apr 11, 2025

Date Added

Mar 17, 2025

This funding opportunity provides financial support for state and local governments, tribes, educational institutions, and nonprofit organizations to conduct chemical analysis of fish tissue samples in the Great Lakes, focusing on monitoring contaminants and improving environmental health.

Environment
Native American tribal organizations
DRL Strengthening Inclusive Governance to Address Shared Pacific Challenges
$750,000
Department of State - Bureau of Democracy Human Rights and Labor
Federal

Application Deadline

Jul 18, 2024

Date Added

Jun 12, 2024

The U.S. Department of State, Bureau of Democracy, Human Rights and Labor (DRL) announces an open competition for a project advances responsive, accountable, and rights-respecting governance for citizens by strengthening environmental governance in Pacific Island countries.

International Development
Nonprofits
Pds-Dhaka-Nofo-Fy2025
$24,990
U.S. Department of State (U.S. Mission to Bangladesh)
Federal

Application Deadline

Aug 18, 2025

Date Added

Jul 8, 2025

This funding opportunity provides financial support to not-for-profit organizations, NGOs, and educational institutions to promote U.S. exports and improve trade relations in Bangladesh by enhancing market access and fostering a transparent business environment.

Business and Commerce
Nonprofits
Using Archived Data and Specimen Collections to Advance Maternal and Pediatric HIV/AIDS Research (R21 - Clinical Trial Not Allowed)
$275,000
Department of Health and Human Services - National Institutes of Health
Federal

Application Deadline

Jul 24, 2024

Date Added

Apr 27, 2024

The purpose of this Notice of Funding Opportunity (NOFO) is to address the needs of the maternal and pediatric HIV scientific community for research data translation and sharing. This initiative will support secondary data analyses using archived HIV/AIDS data and specimens to generate new research questions and findings relevant to the scientific mission and priorities of the NICHD, Maternal and Pediatric Infectious Disease Branch (MPIDB) and Office of AIDS Research (OAR). The goal of this initiative is to encourage applicants to leverage existing datasets and employ new and advanced analysis techniques to answer scientific questions about the epidemiology, pathogenesis, treatment, clinical manifestations and complications of HIV/AIDS in maternal, pediatric and adolescent populations.

Health
State governments
Influenza Modeling and Forecasting 2024
$14,750,000
U.S. Department of Health & Human Services (Centers for Disease Control - NCIRD)
Federal

Application Deadline

Apr 14, 2025

Date Added

Aug 2, 2024

This funding opportunity is designed to support a network of organizations that will improve influenza modeling and forecasting to enhance public health responses and reduce illness in vulnerable populations.

Health
State governments
Advanced Hydrogen and Fuel Cell Technologies to Drive National Goals
$10,000,000
U.S. Department of Energy (Golden Field Office)
Federal

Application Deadline

Jan 31, 2025

Date Added

Oct 24, 2024

Grant Title: Advanced Hydrogen and Fuel Cell Technologies to Drive National Goals aims to fund research and development of hydrogen and fuel cell technologies to help achieve a net-zero emissions economy by 2050, focusing on clean energy solutions for transportation, industrial processes, and energy storage.

Energy
State governments
FFY 2024 FTA Section 5305(e) Transit Planning
$250,000
Arizona Department of Transportation
Federal

Application Deadline

Jan 7, 2025

Date Added

Nov 29, 2024

This funding opportunity provides financial support to Arizona's Metropolitan Planning Organizations and Councils of Governments for transit planning projects that improve rural and regional transit services, particularly for underserved communities.

Transportation
Public and State controlled institutions of higher education
DOD FY24 Lung Cancer, Career Development Award
$1,800,000
DOD-AMRAA (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Jun 17, 2024

Date Added

Mar 26, 2024

The FY24 LCRP Career Development Award supports early-career, independent investigators to conduct impactful research under the mentorship of an experienced lung cancer researcher as an opportunity to obtain the funding, mentoring, and experience necessary for productive, independent careers at the forefront of lung cancer research. Research applications only in the area of mesothelioma will not be accepted. This award is intended to support impactful research projects with an emphasis on discovery.Preliminary data are not required. However, logical reasoning and a sound scientific rationale for the proposed research must be demonstrated.Key elements of this award are as follows:Principal Investigator (PI): PIs must be research- or physician-scientists at an early stage of their independent research careers. PIs must be within 5 years of their first faculty appointment (or equivalent) and exhibit a strong desire to pursue a career in lung cancer research.Mentorship: The Mentor(s) must be an experienced lung cancer researcher(s) as demonstrated by a strong record of funding and publications in lung cancer research. In addition, the Mentor(s) must demonstrate a commitment to developing the PIs career in lung cancer research.Career Development: A Career Development Plan is required and should be prepared with appropriate guidance from the Mentor(s). A clearly articulated strategy for acquiring the necessary skills, competence, and expertise to have a career at the forefront of lung cancer research should be included. The plan should outline how the PI will gain experience in lung cancer research. Because career development is the focus of this award, the PI must commit a minimum of a 25% level of time and effort during the period of performance to conduct lung cancer research under this award.Impact: Research that has high potential impact may lead to major advancements and significantly accelerate progress toward eradicating deaths and suffering from lung cancer.Relevance to Military Health System (MHS) Beneficiaries: The application should clearly articulate how the proposed research is relevant to Service Members, Veterans, and their Families.The PI is required to attend a Department of Defense (DOD) one day in progress review meeting prior to the end of the second year of the award.

Science and Technology
Nonprofits
FY25 Community Policing Development: Law Enforcement Products and Resources
$500,000
U.S. Department of Justice (Community Oriented Policing Services)
Federal

Application Deadline

Jun 24, 2025

Date Added

May 22, 2025

This funding opportunity provides financial support for organizations to create and share resources that improve community policing practices and strengthen trust between law enforcement and the communities they serve.

Law Justice and Legal Services
For profit organizations other than small businesses