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Grants for Small businesses - Federal

Explore 1,549 grant opportunities

FY 2026 Ocean Technology Transition Program
$1,200,000
U.S. Department of Commerce (DOC NOAA - ERA Production)
Federal

Application Deadline

Jul 15, 2026

Date Added

Mar 13, 2026

This funding opportunity provides financial support for universities, nonprofits, and government entities to develop and operationalize advanced ocean and coastal observing technologies that enhance data collection and environmental monitoring.

Environment
Public and State controlled institutions of higher education
2025 "$100,000 Start an SUD Startup" Challenge
$10,000
U.S. Department of Health and Human Services (National Institute on Drug Abuse)
Federal

Application Deadline

Not specified

Date Added

Dec 24, 2025

This grant provides funding and mentorship to interdisciplinary teams developing innovative solutions for drug use and substance use disorders, aiming to support the formation of early-stage biotech startups in the U.S.

Health
Individuals
NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 21, 2024

This funding opportunity supports multi-site clinical trials and biomarker studies aimed at improving stroke treatment, recovery, and prevention, encouraging collaboration with the NIH StrokeNet infrastructure.

Health
State governments
Cardiothoracic Surgical Trials Network (CTSN) Linked Clinical Research Centers
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jul 2, 2025

This funding opportunity supports a collaborative research initiative aimed at advancing cardiothoracic surgery and related fields, inviting a diverse range of organizations to develop innovative solutions for improving health outcomes in patients with cardiovascular conditions.

Health
Public and State controlled institutions of higher education
Innovative Screening Approaches and Therapies for Screenable Disorders in Newborns (R01 - Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 3, 2024

This funding opportunity supports researchers in developing innovative screening methods and therapies for newborn disorders to improve early detection and treatment outcomes.

Health
State governments
Clinical Research Network on Antimicrobial Resistance
$15,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 29, 2026

Date Added

Dec 30, 2025

This funding opportunity supports research institutions and organizations in developing innovative solutions to combat antimicrobial resistance, particularly for vulnerable populations facing serious infections.

Health
City or township governments
Forecast to Renew the Notice of Funding Opportunity Announcement for the Multiple Chronic Disease Research Centers
$55,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

May 13, 2025

This funding opportunity supports research centers focused on improving the prevention and management of multiple chronic diseases, particularly in underserved populations, by encouraging innovative and collaborative projects.

Health
Private institutions of higher education
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 19, 2025

This funding opportunity provides financial support to small businesses in the U.S. for innovative research and development projects that advance health and biomedical innovation without involving clinical trials.

Health
Small businesses
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Apr 3, 2025

This funding opportunity supports researchers exploring the ethical, legal, and social implications of genetic and genomic research, encouraging innovative studies that address real-world issues in these fields.

Education
State governments
Developmental Sciences
$600,000
National Science Foundation
Federal

Application Deadline

Not specified

Date Added

Feb 7, 2025

This funding opportunity supports research that explores various aspects of human development across the lifespan, encouraging innovative studies from a wide range of disciplines and populations to improve understanding of behavioral and cognitive processes.

Science and Technology
Public and State controlled institutions of higher education
Single Source: Chronic Kidney Diseases of UnceRtain Etiology (CKDu) in Agricultural Communities (CURE) Research Consortium- Renal and Environmental Science Core (U01-Clinical Trial Not Allowed)
$1,750,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jul 1, 2026

Date Added

Feb 6, 2026

This funding opportunity provides $1.75 million to support research institutions and organizations investigating the causes and impacts of chronic kidney disease linked to environmental factors in agricultural communities, both in the U.S. and internationally.

Health
State governments
SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 11, 2025

This funding opportunity is designed to assist U.S. small businesses that have received prior SBIR or STTR Phase II or IIB awards in advancing their projects toward commercialization by providing support for later-stage research and development activities.

Health
Small businesses
Nonprofit Security Grant Program
$210,000,000
Department of Homeland Security
Federal

Application Deadline

Not specified

Date Added

Oct 3, 2024

This funding opportunity provides financial support to nonprofit organizations, especially faith-based groups, to improve their security measures against targeted violence and hate crimes.

Safety
Nonprofits
Learning Collaborative for HIV Oral Health and Primary Care Integration
$600,000
U.S. Department of Health & Human Services (Health Resources and Services Administration)
Federal

Application Deadline

Not specified

Date Added

Jul 2, 2025

This funding opportunity provides financial support to organizations focused on improving oral health services for low-income individuals living with HIV by promoting the integration of dental care and primary HIV care through a collaborative learning approach.

Health
Public and State controlled institutions of higher education
Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 19, 2024

This funding opportunity supports research into how certain diabetes medications may influence cancer risk, targeting institutions and organizations capable of conducting innovative studies in this area.

Education
State governments
Innovative Pilot Mental Health Services Research Not Involving Clinical Trials (R34 Clinical Trial Not Allowed)
$225,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 31, 2024

This funding opportunity supports pilot research projects aimed at improving mental health services by generating preliminary data and exploring factors that affect access, quality, and outcomes, targeting a wide range of eligible applicants including educational institutions, nonprofits, and government organizations.

Health
State governments
Rehabilitation Research and Training Center (RRTC) On Employer Practices Leading to Successful Employment Outcomes Among People With Disabilities
$925,000
U.S. Department of Health and Human Services (Administration for Community Living)
Federal

Application Deadline

Not specified

Date Added

Sep 8, 2025

This grant provides funding to various organizations to conduct research and training on effective employer practices that improve job opportunities for individuals with disabilities.

Employment Labor and Training
State governments
Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 25, 2024

This grant provides funding for researchers and institutions to explore the brain's neural circuits related to mental health disorders through invasive techniques, fostering collaboration across various scientific fields to improve understanding and potential treatments.

Health
State governments
BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R61 Basic Experimental Studies with Humans Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Mar 31, 2023

This funding opportunity supports innovative research projects that use invasive technologies to study brain activity in humans, aimed at enhancing our understanding of sensations, perceptions, and behaviors.

Health
State governments
Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required)
$300,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 10, 2024

This funding opportunity provides financial support for short-term clinical trials aimed at improving treatments for arthritis, musculoskeletal, and skin diseases, targeting researchers and institutions focused on innovative healthcare solutions.

Health
State governments