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Grants for Small businesses - Federal

Explore 1,527 grant opportunities

Air Dominance Broad Agency Announcement (BAA)
$750,000,000
U.S. Department of Defense (Munitions Directorate)
Federal

Application Deadline

Oct 31, 2029

Date Added

Apr 15, 2025

This grant invites innovative research proposals from organizations and companies focused on developing advanced technologies to enhance U.S. air combat capabilities and ensure air dominance.

Science and Technology
State governments
Limited Competition: Small Grant Program for ORIP Special Emphasis Research Career Award (SERCA) K01 Recipients (R03 Clinical Trial Not Allowed)
$75,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

May 7, 2026

Date Added

Nov 19, 2024

This funding opportunity provides financial support to veterinary scientists who have received a specific career development award, helping them transition to independent research by enabling small-scale projects that build on their existing work.

Health
State governments
Enhancing Mechanistic Research on Precision Probiotic Therapies (R33 Clinical Trial Optional)
$350,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 2, 2027

Date Added

Nov 1, 2024

This funding opportunity supports research that investigates how individual biological factors, such as genetics and diet, affect people's responses to probiotic therapies, aiming to develop more effective and personalized treatments.

Education
State governments
BRAIN Initiative: Brain Behavior Quantification and Synchronization- Next Generation Sensor Technology Development (U01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 15, 2027

Date Added

Oct 24, 2024

This funding opportunity supports the development of advanced sensors and devices to better understand the connection between brain activity and behavior, inviting applications from a diverse range of organizations, including nonprofits, educational institutions, and small businesses.

Health
State governments
Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development of Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 18, 2026

Date Added

Sep 26, 2024

This grant provides funding for researchers to develop small molecule drugs targeting nervous system disorders, with support from NIH resources for drug discovery and clinical testing.

Education
State governments
Communications, Circuits, and Sensing-Systems
$2,470,673
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Jan 3, 2025

This grant supports innovative research in communication and sensing technologies, targeting engineers and scientists developing advanced systems for applications in healthcare, environmental monitoring, and intelligent transportation.

Science and Technology
For profit organizations other than small businesses
EDU Core Research
$2,500,000
National Science Foundation
Federal

Application Deadline

Oct 1, 2026

Date Added

May 23, 2025

This program provides funding for researchers to explore and improve STEM education, focusing on learning environments, broadening participation, and workforce development across various age groups and settings.

Education
Public and State controlled institutions of higher education
NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)
$249,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 12, 2028

Date Added

Jun 18, 2025

This funding opportunity supports dentist scientists with both clinical dental and research doctoral degrees, helping them transition from mentored postdoctoral training to independent research careers in dental, oral, and craniofacial health.

Health
Individuals
Limited Competition for the Continuation of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) Data Analysis Resource (U24 Clinical Trials Optional)
$600,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 1, 2026

Date Added

May 23, 2025

This funding opportunity supports research institutions and organizations in studying the long-term effects of adolescent alcohol use on brain development and health outcomes, aiming to improve prevention strategies for alcohol use disorders.

Health
State governments
Forecast for NINDS Exploratory Grant Program in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Research (P20 - Clinical Trial Optional)
$3,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 25, 2026

Date Added

May 28, 2025

This funding opportunity supports innovative research initiatives aimed at addressing Myalgic Encephalomyelitis/Chronic Fatigue Syndrome by fostering collaborations among experts in related fields.

Health
State governments
Modular R01s in Cancer Control and Population Sciences (R01 Clinical Trial Optional)
$250,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 5, 2026

Date Added

Nov 8, 2024

This funding opportunity supports innovative research aimed at improving cancer prevention, control, and survivorship through interdisciplinary approaches in behavioral science, epidemiology, and data analytics, targeting a wide range of eligible applicants including universities, nonprofits, and small businesses.

Education
State governments
Automated Processes For Knowledge Discovery And Information Retrieval
$35,000,000
U.S. Department of Defense (Department of the Air Force)
Federal

Application Deadline

Sep 9, 2029

Date Added

Sep 22, 2025

This funding opportunity is designed to support U.S. entities, including universities, nonprofits, and businesses, in developing innovative technologies for analyzing and utilizing multi-source data to improve military decision-making and enhance national defense capabilities.

Science and Technology
Public and State controlled institutions of higher education
Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 18, 2027

Date Added

Oct 2, 2024

This funding opportunity supports researchers and organizations developing biologics-based therapies for nervous and neuromuscular disorders, facilitating their progression from early discovery to clinical trials.

Education
State governments
NSF Research: National Facilities
Contact for amount
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

May 21, 2024

This grant provides funding to research organizations for the operation of specialized national facilities that offer advanced scientific instruments and resources to support diverse research and educational initiatives across various scientific disciplines.

Science and Technology
Public and State controlled institutions of higher education
Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Assay Development and Neurotherapeutic Agent Identification (R61/R33 Clinical Trial Not Allowed)
$499,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 20, 2027

Date Added

Oct 23, 2024

This funding opportunity supports researchers in developing assays and identifying potential neurotherapeutic agents for neurological and neuromuscular disorders, facilitating early-stage drug discovery efforts.

Health
State governments
Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32) PA-25-168
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 25, 2027

Date Added

May 14, 2025

This grant provides funding to U.S. institutions to develop research training programs for predoctoral and postdoctoral students in biomedical and related fields, ensuring a skilled workforce to tackle health research challenges.

Education
State governments
FY 2026 Continuation of Solicitation for the Office of Science Financial Assistance Program
$5,000,000
U.S. Department of Energy (Office of Science)
Federal

Application Deadline

Sep 30, 2026

Date Added

Oct 1, 2025

This funding opportunity supports a wide range of fundamental scientific research projects across various disciplines, including energy, environment, and national security, aimed at advancing knowledge and innovation in the United States.

Science and Technology
Individuals
Research and Development of Naval Power and Energy Systems (N00024-19-R-4145 Broad Agency Announcement (BAA))
Contact for amount
U.S. Department of Defense (Department of the Navy)
Federal

Application Deadline

Feb 6, 2028

Date Added

Aug 25, 2025

This grant provides funding for innovative research projects from industry and academia to improve naval shipboard power and energy systems, focusing on efficiency, resilience, and advanced technologies.

Science and Technology
For profit organizations other than small businesses
NIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 6, 2028

Date Added

Oct 24, 2024

This funding opportunity supports a wide range of organizations in planning and conducting clinical trials focused on improving dental, oral, and craniofacial health interventions.

Health
State governments
Forecast to Publish a Funding Opportunity Announcement for Integrative Neuroscience Initiative on Alcoholism (INIA) Consortia (U01 Clinical Trial Optional)
$10,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

May 1, 2026

Date Added

May 7, 2025

This funding opportunity supports collaborative research consortia focused on understanding the brain and body mechanisms involved in excessive alcohol use and Alcohol Use Disorder, aiming to improve prevention and intervention strategies.

Health
State governments