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Grants for Small businesses - Federal

Explore 1,527 grant opportunities

Enhancing Reuse of NHGRI Data Assets (R03 Clinical Trial Not Allowed)
$125,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 15, 2026

Date Added

Nov 19, 2024

This funding opportunity supports innovative research projects that utilize genomic data from a specific cloud-based platform to answer important biological questions and improve data accessibility for the scientific community.

Health
State governments
FY25 ONR Office Of Naval Research (ONR) Science, Technology, Engineering, and Mathematics(STEM) Education and Workforce Program
Contact for amount
U.S. Department of Defense (Office of Naval Research)
Federal

Application Deadline

Jun 30, 2026

Date Added

Jul 8, 2025

This grant provides funding to a variety of organizations to enhance STEM education and workforce development initiatives, aiming to increase student engagement and proficiency in science, technology, engineering, and mathematics.

Education
For profit organizations other than small businesses
Mechanisms for Amplification of fusion Reaction Rates in Solids (MARRS)
Contact for amount
U.S. Department of Defense (DARPA - Defense Sciences Office)
Federal

Application Deadline

Mar 12, 2026

Date Added

Dec 31, 2025

This grant seeks innovative research proposals to explore and amplify nuclear fusion reaction rates in solid materials at or near room temperature, targeting advancements for practical applications in national defense and energy generation.

Science and Technology
For profit organizations other than small businesses
Clinical and Translational Science Award (UM1 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 28, 2027

Date Added

Sep 5, 2024

This funding opportunity supports medical research institutions in developing collaborative hubs to accelerate the translation of scientific discoveries into effective treatments and address health disparities through innovative research and training programs.

Health
State governments
Enhancing sustainable and integrated health, strategic information, and laboratory systems for quality comprehensive HIV services through technical assistance to the Republic of Rwanda under the President's Emergency Plan for AIDS Relief (PEPFAR)
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control-GHC)
Federal

Application Deadline

Feb 17, 2026

Date Added

Oct 17, 2025

This funding opportunity provides financial support to various organizations working to strengthen Rwanda's health systems and improve comprehensive HIV services through technical assistance and capacity building.

Health
State governments
Battery Network Broad Agency Announcement
Contact for amount
Defense Logistics Agency (DLA), Department of Defense (DoD)
Federal

Application Deadline

Sep 1, 2026

Date Added

Mar 20, 2025

This funding opportunity supports innovative research and development projects that improve defense logistics, supply chain resilience, and operational readiness for organizations aligned with national security objectives.

Science and Technology
For profit organizations other than small businesses
Cellular and Biochemical Engineering
$3,350,043
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Jan 3, 2025

This program provides funding for researchers to advance engineering techniques in cellular and biochemical processes, focusing on innovative biomanufacturing technologies for therapeutic applications.

Science and Technology
For profit organizations other than small businesses
For Funding Opportunity for Maximizing the Scientific Value of Data Generated by the Environmental Influences on Child Health Outcomes (ECHO) Program: Ruth L. Kirschstein NRSA Individual Postdoctoral Fellowship (F32)
$1,260,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 17, 2026

Date Added

May 28, 2025

This funding opportunity supports postdoctoral researchers in utilizing extensive data on environmental influences to advance understanding of child health outcomes across various pediatric health domains.

Health
State governments
Pathways to Enable Open-Source Ecosystems
$1,500,000
National Science Foundation
Federal

Application Deadline

Sep 1, 2026

Date Added

Jun 2, 2025

This program provides funding to U.S.-based organizations to develop and sustain community-driven open-source technology ecosystems that can lead to significant societal benefits.

Science and Technology
Public and State controlled institutions of higher education
Chemical Oceanography
$2,000,000
National Science Foundation
Federal

Application Deadline

Feb 17, 2026

Date Added

Mar 6, 2025

This funding opportunity supports researchers studying the chemistry of oceans and their impact on global environmental processes, aiming to enhance our understanding of marine chemistry and its role in climate and ecological systems.

Natural Resources
Public and State controlled institutions of higher education
Pioneering Aerospace Capabilities, Engineering and Research (PACER)
$50,000,000
U.S. Department of Defense (Air Force -- Research Lab)
Federal
Rolling

Application Deadline

May 10, 2043

Date Added

Jul 26, 2023

This grant provides funding for research and development of innovative aerospace technologies to improve military air vehicle performance and capabilities.

Science and Technology
Small businesses
Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R21 Clinical Trial Not Allowed)
$275,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 18, 2026

Date Added

Jun 10, 2025

This funding opportunity supports researchers and organizations working to improve the readiness for clinical trials in rare diseases by developing biomarkers and understanding disease progression.

Health
Nonprofits
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 21, 2026

Date Added

May 23, 2025

This funding opportunity supports research projects that develop and test culturally relevant health interventions to improve health outcomes in Native American, Alaska Native, and Native Hawaiian communities, emphasizing community engagement and sustainability.

Health
State governments
Foundations for Operating the National Artificial Intelligence Research Resource: the NAIRR Operations Center (NAIRR-OC)
$35,000,000
National Science Foundation
Federal

Application Deadline

Feb 4, 2026

Date Added

Sep 3, 2025

This grant provides funding to a single organization to lead and manage a national initiative that connects researchers and educators with essential artificial intelligence resources and infrastructure.

Science and Technology
Public and State controlled institutions of higher education
Pilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed)
$100,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 16, 2027

Date Added

Oct 29, 2024

This funding opportunity provides financial support for researchers to explore and generate preliminary data on understudied proteins linked to rare diseases, with a focus on enhancing knowledge and tools for future studies.

Health
State governments
DoWs Energy, Installations, and Environment Innovation Partners Programs
$30,000,000
U.S. Department of Defense (Washington Headquarters Services)
Federal

Application Deadline

Jan 8, 2027

Date Added

Feb 28, 2025

This funding opportunity supports a wide range of public and private entities in developing innovative projects that promote environmental sustainability and resilience on military installations across the United States.

Natural Resources
Individuals
Investigator Initiated Innovation in Computational Genomics and Data Science (R01 Clinical Trial Not Allowed)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 7, 2027

Date Added

Nov 19, 2024

This grant provides funding for researchers to develop innovative computational tools and methods that enhance genomic research and data science, with a focus on broad applications to improve human health.

Education
State governments
ROSES 2025: A.4 Rapid Response and Novel Research in Earth Science
Contact for amount
National Aeronautics and Space Administration (NASA Headquarters)
Federal

Application Deadline

Aug 31, 2026

Date Added

Jul 12, 2025

This funding opportunity provides financial support for researchers in the U.S. to conduct rapid and innovative investigations in Earth science, particularly in response to urgent natural events or emerging scientific discoveries.

Science and Technology
Nonprofits
Fluid Dynamics
$9,175,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Jan 3, 2025

This program provides funding for researchers to explore and advance the science of fluid dynamics, focusing on innovative methods and applications that can benefit society and industry.

Science and Technology
For profit organizations other than small businesses
NINR Mentoring Resources and Activities
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Apr 27, 2026

Date Added

May 29, 2025

This funding opportunity supports projects that provide mentoring and career development for nurse scientists to enhance their professional growth and increase the number of nurse researchers with NIH-funded projects.

Health
County governments