GrantExec

Grants for Small businesses - Federal

Explore 1,502 grant opportunities

CHEERS Open Period 1 - All Technical Areas
$484,730,000
U.S. Department of Defense (Air Force -- Research Lab)
Federal
Rolling

Application Deadline

Not specified

Date Added

Aug 8, 2025

This funding opportunity supports a wide range of innovative research projects aimed at improving human health, performance, and sustainability in military and aerospace settings.

Science and Technology
For profit organizations other than small businesses
Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH3 Clinical Trials Not Allowed)
$250,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 14, 2026

Date Added

Oct 16, 2024

Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH3 Clinical Trials Not Allowed) aims to support the clinical validation of already analytically validated biomarkers and assays for cancer detection, diagnosis, and treatment monitoring, ensuring they are reliable and ready for use in clinical studies without conducting new trials.

Education
State governments
FY 2024 2026 Broad Agency Announcement (BAA), National Marine Fisheries Service
Contact for amount
U.S. Department of Commerce (DOC NOAA - ERA Production)
Federal

Application Deadline

Sep 30, 2026

Date Added

Jul 30, 2024

This funding opportunity supports innovative projects and research aimed at sustainable fisheries management, protected species recovery, and marine ecosystem enhancement, targeting a wide range of applicants including educational institutions, nonprofits, and government entities.

Environment
State governments
Continued Development of the Gabriella Miller Kids First Pediatric Data Resource Center (U2C Clinical Trials Not Allowed)
$5,200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 30, 2025

Date Added

May 15, 2025

This funding opportunity supports the development of a national data resource center to improve research on childhood cancers and congenital anomalies, encouraging collaboration among a wide range of organizations and researchers.

Health
State governments
NEI Small Business Innovation Research (SBIR) Cooperative Agreement for Early-Stage Clinical Trials with Greater than Minimal Risk (U44-Clinical Trial Required)
$1,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 23, 2026

Date Added

Dec 1, 2023

This funding opportunity supports small businesses in conducting early-stage clinical trials for innovative treatments of vision-related disorders, ensuring safety and collaboration with the National Eye Institute.

Health
Small businesses
Genetic Medicines And Individualized Manufacturing For Everyone (GIVE)
Contact for amount
U.S. Department of Health and Human Services
Federal

Application Deadline

Feb 27, 2026

Date Added

Sep 29, 2025

This program provides funding to a wide range of organizations, including nonprofits, universities, and businesses, to develop innovative solutions for producing personalized genetic medicines quickly and efficiently, improving patient access across the United States.

Health
For profit organizations other than small businesses
NIGMS National and Regional Resources (R24 - Clinical Trial Not Allowed) PAR-25-416
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 14, 2027

Date Added

May 14, 2025

This funding opportunity supports the development and maintenance of shared biomedical research resources that provide advanced technologies and services to researchers across multiple states or nationally, ensuring broad access for academic investigators.

Science and Technology
State governments
Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed)
$4,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Dec 3, 2027

Date Added

Dec 6, 2024

This funding opportunity supports innovative research projects that utilize existing data to enhance understanding of substance use and related disorders, targeting a wide range of applicants including universities, nonprofits, and government entities.

Health
Public and State controlled institutions of higher education
CHEERS Open Period 2 - All Technical Areas
$499,870,000
U.S. Department of Defense (Air Force -- Research Lab)
Federal

Application Deadline

Sep 30, 2027

Date Added

Aug 8, 2025

This funding opportunity is designed to support innovative research and development projects that enhance national defense across various technical fields, inviting submissions from both U.S. and foreign entities.

Science and Technology
Nonprofits
Notice of Intent to Publish a Funding Opportunity Announcement for Single Source for Continuation of the Environmental Determinants of Diabetes in The Young Study (TEDDY) Data Coordinating Center (U01 Clinical Trial Not Allowed)
$6,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 26, 2025

Date Added

May 13, 2025

This funding opportunity provides $6 million to the University of South Florida to continue managing the TEDDY study's Data Coordinating Center, which investigates the environmental causes of type 1 diabetes in children.

Health
State governments
NIEHS Worker Training Programs SBIR E-Learning for HAZMAT and Emergency Response (R43/R44 Clinical Trial Not Allowed)
$688,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 20, 2025

Date Added

May 22, 2025

This funding opportunity provides financial support for small businesses to develop innovative e-learning training products that enhance the safety and health training of workers dealing with hazardous materials and emergency response situations.

Health
Small businesses
Injury Prevention and Control Research and State and Community Based Programs - RFA-GH-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Oct 13, 2025

Date Added

Oct 13, 2023

This funding opportunity supports state and community-based programs and research initiatives focused on preventing and controlling injuries, available to a wide range of applicants including governments, universities, and nonprofits.

Health
County governments
Implementation Research for Multi-morbidity Management in the Context of Non-communicable Diseases in Low- and Middle-Income Countries and US Tribal Populations (R01 Clinical Trial Optional)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 5, 2025

Date Added

Oct 28, 2024

This funding opportunity supports research projects aimed at improving the management of multiple chronic diseases in low- and middle-income countries and American Indian/Alaska Native populations in the U.S. through innovative, community-centered healthcare strategies.

Education
State governments
Data Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative U24 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 11, 2026

Date Added

May 22, 2025

This funding opportunity supports the establishment of a Data Coordinating Center to manage and analyze data for multi-site clinical trials focused on heart, lung, and blood health research, aimed at a wide range of eligible organizations including universities and nonprofits.

Health
State governments
DOE Industrial Training & Assessment Centers (ITAC) Implementation Grants
$300,000
U.S. Department of Energy
Federal
Rolling

Application Deadline

Not specified

Date Added

Oct 3, 2024

This program provides funding to small and medium-sized manufacturing companies and water/wastewater treatment facilities to implement energy efficiency improvements and reduce emissions, while also creating job opportunities in disadvantaged communities.

Energy
Small businesses
Arctic Research Opportunities
$50,000,000
National Science Foundation
Federal

Application Deadline

Jan 15, 2026

Date Added

May 21, 2025

This funding opportunity provides financial support for U.S.-based researchers to study the Arctic's environment and communities, with a focus on collaboration with Indigenous peoples and advancing understanding of Arctic change and its global impacts.

Science and Technology
Public and State controlled institutions of higher education
NICHD Small Research Grant Program (R03 Basic Experimental Studies with Humans Required)
$50,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 16, 2025

Date Added

Nov 19, 2024

This funding opportunity provides financial support for small-scale research projects that involve basic experimental studies with human participants, focusing on understanding fundamental aspects of human development and health-related behaviors.

Health
State governments
NCI Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 14, 2027

Date Added

Nov 21, 2024

This grant provides financial support to promising postdoctoral researchers in cancer-related fields, helping them transition to independent faculty positions through a structured mentorship and research development program.

Education
State governments
Statistics
Contact for amount
National Science Foundation
Federal

Application Deadline

Dec 15, 2025

Date Added

Dec 27, 2024

This program provides funding for researchers and teams to develop and apply advanced statistical theories and methods that address uncertainty in scientific and engineering fields.

Science and Technology
Public and State controlled institutions of higher education
Advancing HIV/AIDS Research within the Mission of the NIDCD (R21 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 7, 2028

Date Added

Jan 9, 2025

This funding opportunity provides support for innovative research on how HIV/AIDS affects communication and sensory functions, targeting researchers and institutions focused on hearing, balance, taste, smell, voice, speech, and language disorders in people living with HIV.

Health
State governments