Grants for Small businesses - Federal

This Notice of Funding Opportunity (NOFO) invites applications for the continued support and advancement of the Mutant Mouse Resource and Research Centers (MMRRC). The MMRRC consortium is expected to facilitate research by identifying, acquiring, evaluating, characterizing, cryopreserving, and distributing mutant mouse strains to qualified biomedical investigators. A regional network of four MMRRCs and an Informatics, Coordination and Service Center (ICSC) collectively serve the needs of the biomedical research community for transgenic, knockout and other genetically-engineered mutant mice and related biomaterials. MMRRC strains are held to the highest standards to optimize reproducibility of studies and assure scientific rigor and transparency; all submitted strains are thoroughly reviewed and documented and include additional quality control measures. The Program Director/Principal Investigator (PD/PI) of each MMRRC in addition to the major resource activities is required to develop a small high risk, high return, research pilot project that complements the goals and needs of the MMRRC consortium. ORIP intends to fund up to four awards, but the overall number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications Award Budget Requested Direct Costs must reflect actual needs of the project. For Renewal (a.k.a. Type 2) applications, no more than a 5 percent (direct cost) increase from the last non-competing year will be accepted. ORIP intends to fund up to four awards, but the overall number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications

This grant provides funding for researchers to develop and implement strategies that improve HIV prevention and care for individuals who use stimulants, particularly those who also use opioids or other substances, while promoting diversity and community engagement in the research process.

This grant provides funding and support to early-stage U.S. startups developing innovative technologies that can meet critical needs of the Department of Defense.

This grant provides funding for researchers to develop advanced human cell-based systems that better mimic the complex functions of the nervous system, aiming to improve the understanding and treatment of brain and spinal cord disorders.

This program provides funding for researchers and innovators to develop advanced technologies for rapidly identifying and sequencing complex protein-based biothreats, enhancing national security and defense capabilities.

This funding opportunity supports research using advanced cellular models to investigate HIV interactions with tissues related to diabetes, digestive, and kidney diseases, particularly focusing on HIV persistence, latency, and related health issues.

This funding opportunity supports collaborative research efforts to improve the prevention, treatment, and understanding of cancers associated with HIV, involving various specialized teams and clinical trials accessible to diverse populations.

This funding opportunity supports researchers analyzing existing genomic data related to dental, oral, and craniofacial health to address research gaps and improve health outcomes.

This funding opportunity provides financial support for projects that enhance the domestic processing, manufacturing, and recycling of critical battery materials to strengthen U.S. supply chains and reduce reliance on foreign sources.

This funding opportunity supports early postdoctoral fellows from diverse backgrounds in cancer research, providing them with mentorship and training to advance their careers in addressing health disparities and enhancing the cancer research workforce.

This funding opportunity provides financial support for engineering studies to develop infrastructure for transporting captured carbon dioxide, targeting private companies, governments, non-profits, and educational institutions committed to reducing greenhouse gas emissions and promoting community benefits.

This funding opportunity provides financial support to U.S.-based small businesses that have previously received Phase I awards to further develop and commercialize innovative research in agriculture, food systems, and environmental sustainability.

This grant provides funding to organizations that will deliver training and support to improve early childhood education and development practices for children from birth to age five in Head Start and Early Head Start programs.

The U.S. Department of State, Bureau of Oceans and International Environmental and Scientific Affairs (OES) announces an open competition (see eligibility information in Funding Announcement), under the Toxic Chemicals earmark to reduce and mitigate environmental contamination and human exposures to lead by supporting capacity-building efforts for environmentally sound end-of-life management of lead-acid batteries (LABs) and used lead-acid batteries (ULABs) in Africa. This program aims to reduce lead pollution as well as promote and advance environmentally sustainable consumption and production at international, national, and subnational levels.

This funding opportunity supports small businesses that have completed a Phase II SBIR or STTR award in advancing clinical trials and research projects for medical products, particularly those requiring federal regulatory approval, while encouraging partnerships with investors to ensure commercial viability.

This funding opportunity provides financial support to organizations that will help improve diabetes prevention and management for underserved populations by offering expertise, training, and resources to enhance health equity.

This funding opportunity provides financial support to institutions with active Clinical and Translational Science Awards to develop innovative programs that address critical challenges in clinical research and improve the efficiency of translating scientific discoveries into practical applications.

This funding opportunity supports U.S.-based small businesses in developing and manufacturing therapeutic extracellular vesicles for regenerative medicine applications, focusing on tissue and organ repair.

This funding opportunity provides financial support for innovative research projects aimed at understanding the neurological and mental health effects of chronic illnesses linked to infections, such as Long COVID and chronic fatigue syndrome, encouraging studies that explore their underlying mechanisms.

The National Institutes of Health (NIH) and the Centers for Disease Control and Prevention (CDC) hereby notify Small Business Concerns (SBCs) holding Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) grants that funds are available for administrative supplements to improve the diversity of the research workforce by recruiting and supporting students, postdoctorates, and eligible investigators from groups that have been shown to be nationally underrepresented in health-related research or in the SBIR and STTR programs. This supplement opportunity is also available to PD(s)/PI(s) of research grants who are or become disabled and need additional support to accommodate their disability in order to continue to work on the research project. Administrative supplements must support work within the scope of the original project. This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary study to a clinical trial. Applicants to this FOA are permitted to propose research experience in a clinical trial led by a mentor or co-mentor.