GrantExec

Grants for Small businesses - Federal

Explore 1,501 grant opportunities

ROSES 2025: C.2 Solar System Science
Contact for amount
National Aeronautics and Space Administration (NASA Headquarters)
Federal

Application Deadline

Mar 31, 2026

Date Added

Jul 12, 2025

This funding opportunity supports U.S. institutions conducting scientific research to enhance our understanding of the solar system using spacecraft mission data and other research methods.

Science and Technology
Public and State controlled institutions of higher education
BROAD AGENCY ANNOUNCEMENT (BAA) for Extramural Biomedical and Human Performance Research and Development Department of Defense
$10,000,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Jul 31, 2028

Date Added

Jul 27, 2023

This funding opportunity supports research projects that improve medical and human performance capabilities for military personnel, focusing on innovative solutions for Special Operations Forces in challenging environments.

Health
Nonprofits
2025 Human Exploration Research Opportunities (HERO) NOFO
$1,500,000
National Aeronautics & Space Administration (NASA Johnson Space Center)
Federal
Rolling

Application Deadline

Oct 31, 2025

Date Added

Nov 6, 2024

This funding opportunity supports U.S.-based universities, non-profits, and laboratories in conducting research to enhance astronaut health and performance during long-duration space missions, particularly for exploration to the Moon and Mars.

Science and Technology
Public and State controlled institutions of higher education
Forecast to Publish a Funding Opportunity Announcement for Cancer Center Support Grants (CCSGs) for NCI-designated Cancer Centers (P30 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 25, 2026

Date Added

May 15, 2025

This funding opportunity provides financial support to designated cancer research centers to enhance their capabilities in cancer research, prevention, and treatment, fostering collaboration and innovation in the fight against cancer.

Health
State governments
Single-Site Investigator-Initiated Clinical Trials (R61/R33 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 10, 2025

Date Added

May 22, 2025

This funding opportunity supports researchers in conducting single-site clinical trials focused on heart, lung, and blood health, encouraging innovative trial designs and community engagement.

Health
State governments
Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (U44 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 18, 2027

Date Added

Oct 2, 2024

This grant provides funding to U.S. small businesses for developing biologics-based therapies aimed at treating neurological and neuromuscular disorders.

Education
Small businesses
Advanced Cyber Effects for Strategic Operations
$99,980,000
U.S. Department of Defense
Federal

Application Deadline

Jul 10, 2030

Date Added

Sep 29, 2025

This grant provides funding for innovative research and development of cyber operations prototypes to enhance the U.S. Department of Defense's capabilities in the cyber domain, targeting a wide range of eligible applicants including universities, businesses, and research organizations.

Science and Technology
State governments
Defense Sciences Office (DSO) Office-wide BAA
Contact for amount
U.S. Department of Defense (DARPA - Defense Sciences Office)
Federal

Application Deadline

Jun 2, 2026

Date Added

Jun 4, 2025

This grant provides funding for innovative research proposals that advance scientific and technological breakthroughs to enhance national security, targeting a wide range of applicants including private institutions, nonprofits, and small businesses.

Science and Technology
For profit organizations other than small businesses
Metal Casting BAA0001-21
Contact for amount
Defense Logistics Agency (DLA), Department of Defense (DoD)
Federal

Application Deadline

Jun 30, 2026

Date Added

Mar 20, 2025

This funding opportunity supports research and development in metal casting technologies to enhance military applications and meet national defense needs.

Science and Technology
For profit organizations other than small businesses
Small Business Transition Grant for New Entrepreneurs (R43/R44 Clinical Trial Required)
$2,045,816
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 5, 2026

Date Added

Apr 27, 2024

This funding opportunity supports early-career scientists transitioning to small business roles by providing financial resources for clinical trials, mentorship, and entrepreneurial training to foster their development and commercialization of innovative technologies.

Health
Small businesses
United States Military Academy Broad Agency Announcement
Contact for amount
U.S. Department of Defense (Dept of the Army -- Materiel Command)
Federal

Application Deadline

Mar 31, 2027

Date Added

May 28, 2025

This grant invites educational institutions, nonprofits, businesses, and government entities to propose innovative research projects that enhance the capabilities of the U.S. Army across various scientific and engineering fields.

Science and Technology
City or township governments
Social disconnection and Suicide Risk in Late Life (R21 Clinical Trial Optional)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 16, 2025

Date Added

Nov 19, 2024

This funding opportunity supports innovative research projects that explore the links between social disconnection and suicide risk in older adults, encouraging multidisciplinary approaches to address health disparities and improve mental health outcomes.

Health
State governments
NSF's Eddie Bernice Johnson Inclusion across the Nation of Communities of Learners of Underrepresented Discoverers in Engineering and Science (INCLUDES) Initiative
$5,500,000
National Science Foundation
Federal

Application Deadline

Oct 28, 2025

Date Added

May 23, 2025

This initiative provides funding to organizations and institutions aiming to increase diversity and inclusivity in STEM fields by supporting collaborative projects that address the participation of underrepresented and underserved groups.

Science and Technology
Public and State controlled institutions of higher education
NIMH Biobehavioral Research Awards for Innovative New Scientists (NIMH BRAINS) (R01 Clinical Trial Optional)
$3,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 20, 2025

Date Added

May 29, 2025

This funding opportunity supports early-career scientists conducting innovative research to improve the understanding, diagnosis, treatment, or prevention of mental health disorders.

Health
State governments
Forecast to Publish a Notice of Funding Opportunity (NOFO) for NCI Community Oncology Research Program (NCORP) Academic Community Sites (UG1 Clinical Trials Not Allowed)
$73,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 14, 2025

Date Added

May 29, 2025

This funding opportunity is designed to support academic and community healthcare organizations in enrolling diverse patient populations in cancer clinical trials, enhancing cancer research in underserved areas.

Health
State governments
Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes (R01 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 7, 2028

Date Added

Nov 1, 2024

This funding opportunity supports clinical trials that evaluate effective mental health interventions and services for individuals transitioning from acute care to long-term support, particularly for underserved populations.

Health
State governments
Viral INfections in the Young Lung- The VINYL Clinical Consortium (UG3/UH3 Clinical Trial Optional)
$1,640,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 10, 2025

Date Added

Jul 9, 2025

This funding opportunity supports research institutions and organizations in developing a comprehensive study on viral respiratory infections in young children, aiming to improve understanding and treatment of these common illnesses.

Health
For profit organizations other than small businesses
NINDS Exploratory Clinical Trials for Small Business (R41/R42 Clinical Trial Required)
$1,972,828
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 5, 2026

Date Added

Nov 27, 2023

This funding opportunity provides financial support for small businesses to conduct exploratory clinical trials focused on neurological disorders, including the development of drugs, devices, and therapies.

Health
Small businesses
Seeking Products to Address Social Needs impacting Substance Use Disorders (SUD) (R43/R44 Clinical Trial Optional)
$295,924
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 13, 2026

Date Added

Sep 28, 2023

This funding opportunity is designed to support small businesses in developing innovative technologies that address social needs impacting individuals with substance use disorders, excluding alcohol, to improve access to care and enhance recovery outcomes.

Education
Small businesses
NSF STEM K-12
$750,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Aug 23, 2025

This funding opportunity supports research and innovative projects aimed at improving STEM education in K-12 settings, encouraging collaboration among educational institutions, non-profits, and for-profit organizations to enhance teaching and learning through emerging technologies.

Education
Public and State controlled institutions of higher education