Federal Health Grants

This Notice of Intent to Publish is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects for the following Notice of Funding Opportunity (NOFO), which is expected to be published in January 2024, with an anticipatedapplication receipt date in May 2024. The Brain Research through Advancing Innovative Neurotechnologies(BRAIN) Initiative intends to promote a new initiative by publishing a NOFO to solicit applications that would support development and preclinical testing, beginning withproof of concept,of next-generation recording and/or modulation devices for human use to further our understanding of the human central nervous system and treat nervous system disorders. This NOFO will utilize the R18 activity code. Details of the planned NOFO are provided below.

This funding opportunity provides financial support to organizations that aim to improve services for older adults with behavioral health issues in senior nutrition programs, focusing on creating accessible and culturally sensitive practices.

This funding opportunity invites researchers to develop and apply advanced imaging techniques to better understand the role of inflammation in cancer, fostering collaboration between cancer scientists and imaging experts.

This funding opportunity supports research training for underrepresented students and health professionals in cardiovascular, pulmonary, hematologic diseases, and sleep disorders, aiming to increase diversity in the biomedical research workforce and reduce health disparities.

The Rural Economic Development Loan and Grant program provides funding for rural projects through local utility organizations. USDA provides zero-interest loans to local utilities which they, in turn, pass through to local businesses (ultimate recipients) for projects that will create and retain employment in rural areas. The ultimate recipients repay the lending utility directly. The utility then is responsible for repayment to USDA. USDA provides grants to local utility organizations which use the funding to establish Revolving Loan Funds (RLF). Loans are made from the revolving loan funds to projects that will create or retain rural jobs. When the revolving loan fund is terminated, the grant is repaid to USDA.The Agency anticipates the following maximum amounts per award: Loans - $2,000,000; Grants - $300,000.

This Funding Opportunity Announcement (FOA) allows for renewal and competitive revision applications, and their resubmissions, for funded U24?Research Resource/Infrastructure?applications?that?support?large-scale, complex research programs focused on?Alzheimers disease (AD) and?Alzheimers disease-related dementias (ADRD).?It is anticipated that such programs will likely involve a team of investigators within a single institution or a consortium of?institutions?and?align with one or more?AD/ADRD implementation research milestones?supporting the?research goals of the??National Plan to Address Alzheimers and Related Dementias.

The purpose of the NIDA Animal Genetics Program is to identify genetic, genomic, and molecular (epi)genetic variants that underlie: 1. Phenotypes associated with addictive behaviors and/or vulnerability to distinct stages along the substance use disorder (SUD) trajectory (e.g. initial/acute use, escalation of use, acquisition of tolerance, dependence, uncontrolled use, abstinence and relapse or recovery); 2. Behaviors associated with SUD (e.g. impulsivity, novelty seeking, delayed discounting, and other genetically-associated phenotypes); and 3. Comorbidities that demonstrate genetic correlations with phenotypes and behaviors linked with SUD (e.g. anxiety, stress, poor maternal care, social defeat, and other paradigms). Applications may examine any type of variant, including single nucleotide variants (SNVs), indels, large and small structural variants, and all types of mobile DNA. NIDA encourages applications that take genomics, multi-omics, and/or data-based approaches that integrate multi-level omics data, delineate gene networks, and/or uncover the function of known or newly discovered genetic or epigenetic variants. NIDA expects these studies to uncover novel mechanisms that contribute to SUD and facilitate the discovery of targets for intervention and guide the development of individualized therapeutics to treat these different aspects of SUD.

This funding opportunity provides financial support for research and evaluation projects aimed at improving malaria control and prevention strategies in Kenya, specifically targeting collaborations with local health institutions.

This funding opportunity provides financial support to state egg regulatory programs to help them meet national safety standards and improve egg safety oversight.

This funding opportunity provides financial support to Indian Tribes and tribal organizations for engaging AmeriCorps members in community service projects that address various needs, including youth mental health, education, cultural preservation, and health services.

This funding opportunity provides financial support to early-career researchers who have received specific NIAMS awards, enabling them to conduct small-scale studies and gather data to advance their research and secure future funding.

This funding opportunity supports research to develop and test behavioral interventions aimed at reducing sexual risk behaviors and increasing the use of HIV prevention methods among HIV-negative Black and Hispanic men who have sex with men and use substances before or during sex.

This funding opportunity provides support for the development and management of early-phase cancer prevention clinical trials, focusing on evaluating interventions to reduce cancer risk across various organ sites.

This funding opportunity supports research projects that use genome editing techniques to explore the genetic factors contributing to substance use disorders, encouraging diverse organizations to participate in advancing addiction science.

The "Advanced Development and Validation of Emerging Biospecimen Science Technologies for Basic and Clinical Cancer Research" grant aims to fund exploratory research projects that focus on improving the quality of cancer samples through the development and validation of innovative technologies, which will help in preserving sample integrity, establishing quality control, and reducing variations in sample quality, ultimately enhancing cancer research, diagnosis, and treatment.

This funding opportunity provides financial support for organizations to conduct research on telehealth services, particularly focusing on improving access and addressing disparities for underserved populations in the United States.

This funding opportunity supports research training for students from underrepresented backgrounds in health disparities and minority health, enabling them to gain valuable experience through domestic and international research programs.

This funding opportunity supports researchers in conducting single-site clinical trials focused on heart, lung, and blood health, encouraging innovative trial designs and community engagement.

The "HEAL Initiative: Understanding Individual Differences in Human Pain Conditions" grant aims to fund research that explores the differences in how individuals experience pain, with the goal of improving personalized pain treatment strategies and understanding the impact of factors like additional health conditions or substance use.

HIV infection and substance use are comorbid conditions that bidirectionally and synergistically influence the deleterious outcomes in people who suffer from substance use disorders (SUD). The persistence and transcriptional reactivation of HIV lead to the development of neuropathological complications. Strategies to address viral latency include silencing of HIV transcription and reactivation and clearance. The goal of this initiative is to support research aimed at (1) identification of targets and pathways by which transcriptional activity of HIV can be suppressed in HIV reservoirs including the CNS in people with SUD, and (2) application of emerging small molecule drug discovery approaches to identify novel compounds that can be utilized as pharmacological probes and as drugs to suppress HIV transcription in people with HIV-SUD comorbidity.