Federal Health Grants

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. This Funding Opportunity Announcement (FOA) is soliciting Transformative Research Award applications to support individual scientists or groups of scientists proposing groundbreaking, exceptionally innovative, original, and/or unconventional research that has the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies related to Down syndrome. For the program to support the best possible researchers and research, applications are sought which reflect the full diversity of the nations research workforce. Individuals from diverse backgrounds, including those from underrepresented groups and from the full spectrum of eligible institutions in all geographic locations are strongly encouraged to apply to this Funding Opportunity Announcement. Applications are welcome in all topics relevant to Down syndrome-related research or its co-occurring conditions. No preliminary data are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in research related to Down syndrome.

The National Institutes of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) with other NIH Institutes and Centers (ICs), intends to publish a new Notice of Funding Opportunity (NOFO) to solicit applications for multi-PI team-based, challenging, high impact projects to improve understanding of mechanisms of chronic pain in children and adolescents and to accelerate the development of age appropriate, patient/family centered prevention and therapeutic approaches. This research will seek to advance an integrated understanding of the biological, psychological, and social factors that contribute to pediatric chronic pain. NIH is interested in pain research in infants, children, and adolescents that includes those with intellectual and physical disabilities and/or those who experience health disparities (e.g., diverse race/ethnicity, sexual and gender minorities, socioeconomically disadvantaged, medically underserved communities, people with limited English proficiency). NIH encourages applicants to consider community-engaged research and interdisciplinary, collaborative applications to be developed in partnership with patient communities and/or community organizations where possible. The long-term goal is to develop improved knowledge of specific pediatric pain conditions as well as pain associated with diverse diseases/disorders, to improve understanding of pain in the context of child development and to facilitate the stratification of patients with specific pain conditions and co-morbidities to accelerate chronic pain prevention and therapeutic clinical trials. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The NOFO is expected to be published in May 2024 with an expected application due date in Fall 2024. This NOFO will utilize the UC2 Research Project Cooperative Agreements activity code. Details of the planned NOFO are provided below.

This funding opportunity provides administrative support to an organization dedicated to increasing the number of Native Hawaiian health care professionals through scholarships for students pursuing health care careers in Hawaii.

The "Limited Competition: NIGMS Mature Synchrotron Resources for Structural Biology" grant aims to fund well-established structural biology resources at synchrotron facilities, with the goal of maintaining or upgrading them to current best practices, promoting their availability to the biomedical research community, and providing user training and support.

This grant provides funding for researchers to investigate the harmful effects and underlying mechanisms of acute exposure to ultra-potent synthetic opioids, aiming to develop effective treatments and countermeasures for public health emergencies.

This funding opportunity provides financial support to small businesses developing new medications for treating alcohol use disorder and related organ damage, with a focus on advancing these therapies toward FDA approval.

This grant provides funding to healthcare organizations and community-based entities to improve mental health and substance use care for women, particularly those affected by the COVID-19 pandemic, through training, technical assistance, and the development of resources.

The purpose of the Promote Mental Health Among the Health Professional Workforce (PMHW) program is to support health care entities, including entities that provide health care services, such as hospitals, community health centers, and rural health clinics, or medical professional associations, to promote wellness, resilience, and mental health of the health care professional workforce using established or enhanced evidence-based or evidence-informed programs to transform organizational cultures.

This funding opportunity provides financial support to various organizations, including local governments and nonprofits, to hire and train professionals who conduct sexual assault forensic exams, particularly in underserved communities.

The purpose of the program is to promote the delivery of health care services to rural underserved populations in the rural Northern Border Regional Commission (NBRC) service area of Maine, New Hampshire, New York, and Vermont. Through a consortia of local health care and social service providers, communities can develop innovative approaches to challenges related to specific health needs that expand clinical and service capacity. This program supports HRSA's collaboration with the Northern Border Regional Commission.

This funding opportunity provides financial support for the early development of innovative drugs aimed at preventing, slowing, or treating Alzheimer's disease and its symptoms.

This funding opportunity provides $77.5 million to local Mozambican organizations to enhance HIV services, strengthen health systems, and expand community outreach in Sofala and Niassa provinces, aiming for epidemic control by 2031.

This funding opportunity supports research projects that aim to improve access and effectiveness of treatment for Alcohol Use Disorder, particularly for underrepresented populations such as racial and ethnic minorities, rural communities, and LGBTQ+ groups.

The Black Lung Clinic Programs primary goal is to reduce the morbidity and mortality associated with occupation related coal mine dust lung disease (CMDLD), also known as black lung disease, by providing: Medical services. Outreach services. Educational services. Benefits counseling services. All recipients are required to provide certain services to coal miners in their service area. We also provide additional requirements to the minimum required services, to make sure that the quality and breadth of services coal miners receive is sustained in all service areas.

The purpose of the NIH Mentored Research Scientist Development Award (K01) is to provide support and protected time (three to five years) for an intensive, supervised career development experience in the biomedical, behavioral, or clinical sciences leading to research independence. Although all of the participating NIH Institutes and Centers (ICs) use this support mechanism to support career development experiences that lead to research independence, some ICs use the K01 award for individuals who propose to train in a new field or for individuals who have had a hiatus in their research career because of illness or pressing family circumstances. Other ICs offer separate K01 FOAs intended to increase research workforce diversity.

NHGRI aims to setup a research Consortium, ML/AI Tools to Advance Genomic Translational Research (MAGen), to collaboratively explore the feasibility of developing Machine Learning (ML) and Artificial Intelligence (AI) tools that can enhance the accuracy and precision of predicting how individuals with pathogenic genetic variants manifest disease. The primary goal is to identify both genomic and non-genomic factors influencing disease development in individuals carrying pathogenic genetic variants. The ML/AI tools will leverage existing multimodal genomic and non-genomic data and will be cross validated in genomic translational research settings to ensure the accuracy and generalizability of the tools for translational purposes. In addition, the Consortium will explore the ethical, legal, and social implications (ELSI) of integrating ML/AI tools into genomic medicine through the establishment of an ELSI Framework for their development, and through implementation of ELSI research projects.

This funding opportunity supports innovative clinical trials aimed at developing advanced imaging technologies to visualize the inner ear's structures and functions in living patients with high precision.

This funding opportunity supports collaborative research projects by multidisciplinary teams focused on addressing significant challenges related to substance use disorders and their health consequences.

This funding opportunity supports small businesses in the U.S. to develop innovative solutions for diagnosing and treating health issues related to non-disordered drug use, such as complications from opioid and stimulant use.

This funding opportunity supports research that explores how structural racism affects brain function and substance use risk, aiming to develop effective prevention strategies for substance use disorders among racial and ethnic minority populations.