Federal Health Grants

This funding opportunity supports academic and industrial partnerships to develop new vaccines aimed at preventing tuberculosis infection and disease, addressing the urgent need for effective solutions against rising TB rates.

This funding opportunity provides financial support to various organizations to assist the Botswana Ministry of Health in implementing effective HIV prevention and treatment programs, particularly for underserved populations.

The "Genetic Architecture of Mental Disorders in Ancestrally Diverse Populations II" grant aims to expand the existing mental health research network to include larger studies, provide guidance to the scientific community, and support career development for researchers from low-resource settings worldwide.

The purpose of this additional funding is to increase access to high quality family-centered HIV health care services for low-income women, infants, children, and youth, commonly abbreviated as WICY. HRSA intends funding under this program to support one short-term activity that can be completed by the end of the one-year period of performance. You may propose an expansion of an activity previously supported under the FY2023 or FY2024 RWHAP Part D Supplemental funding (HRSA-23-050; HRSA-24-061) or Part C Capacity Development funding (HRSA-23-052; HRSA-24-062) for either an HIV Care Innovation or Infrastructure Development activity; however, HRSA will not fund the same activity in FY 2025 as HRSA funded previously in FY 2023 or FY 2024. If the proposed project is an expansion of a previously funded activity, you must provide a clear rationale for how the proposed activity builds upon and furthers the objectives of the previously funded activity.

This funding opportunity supports early-career scientists in the U.S. who are focused on conducting impactful research to improve worker health and safety in various industries.

This funding opportunity supports educational programs that promote diversity in neuroscience research by providing mentoring, research experiences, and skill development for underrepresented individuals in the field.

This funding opportunity supports researchers in exploring and validating the biological mechanisms linking HIV, substance use disorders, and opioid exposure at a single-cell level, with a focus on data mining existing datasets and conducting functional validation studies.

This grant provides funding for researchers to develop and test innovative behavioral treatments for individuals struggling with drug and alcohol misuse, particularly focusing on improving treatment effectiveness and accessibility for diverse populations.

This program will help rural hospitals expand their services to meet community health needs while increasing their revenues. The program will achieve these goals by providing expert technical assistance to rural hospitals to conduct market assessments, determine ways to enhance existing service lines, and start new service lines to keep services locally. The program will also provide direct financial support to help with associate costs of service lines. This program will also have the affect of helping facilities address long-standing rural disparities.

This notice of funding opportunity (NOFO) provides funding to conduct efficacy studies in an established rare disease preclinical model to demonstrate that a proposed therapeutic agent warrants further development. In addition to preclinical efficacy, accompanying pharmacodynamic and pharmacokinetic studies would be supported. Therapeutic agents include small molecules, biologics or biotechnology-derived products. The goal of this NOFO is to spur therapeutic development for rare diseases by advancing projects to the point where they would attract subsequent investment supporting full Investigational New Drug (IND) application development or progression to clinical trials in the case of repurposing or repositioning.

This grant provides funding to nonprofit organizations and government entities to deliver essential family planning and reproductive health services to low-income and underserved populations across the United States.

This Funding Opportunity Announcement (FOA) invites applications to enhance the pool of highly trained investigators from diverse backgrounds, including those from groups underrepresented in research areas of interest to the NHLBI. The career development will take place under the guidance of an experienced mentor in the biomedical, behavioral or clinical sciences leading to research independence. It is targeted toward individuals whose basic, clinical, and translational research interests are grounded in the advanced methods and experimental approaches needed to solve problems related to cardiovascular, pulmonary, and hematologic diseases and sleep disorders in the general and health disparities populations. This FOA invites applications from institutions with eligible faculty members to undertake special study and supervised research under a mentor who is an accomplished investigator in the research area proposed and has experience in developing independent investigators. This FOA is designed specifically for candidates proposing to serve as the lead investigator of an independent clinical trial, a clinical trial feasibility study, or a separate ancillary clinical trial, as part of their research and career development. Applicants not planning an independent clinical trial, or proposing to gain research experience in a clinical trial led by another investigator, must apply to the companion FOA (see RFA-HL-22-011).

The Career Transition Award for NINDS Intramural Clinician-Scientists (K22 Clinical Trial Required) aims to support licensed neurologists and neurosurgeons in the NINDS intramural program as they transition to independent academic positions while leading clinical trials and advancing their research careers in neuroscience.

The purpose of this program is to support states and tribes with implementing youth suicide prevention and early intervention strategies in schools, institutions of higher education juvenile justice systems, substance use and mental health programs, foster care systems, and other child and youth-serving organizations. SAMHSA was given the authority to address priority substance abuse treatment, prevention and mental health needs of regional and national significance through assistance (grants and cooperative agreements) to States, political subdivisions of States, Indian tribes and tribal organizations, and other public or nonprofit private entities. Under these sections, CSAT, CMHS and CSAP seek to expand the availability of effective substance abuse treatment and recovery services available to Americans to improve the lives of those affected by alcohol and drug additions, and to reduce the impact of alcohol and drug abuse on individuals, families, communities and societies and to address priority mental health needs of regional and national significance and assist children in dealing with violence and traumatic events through by funding grant and cooperative agreement projects. Grants and cooperative agreements may be for (1) knowledge and development and application projects for treatment and rehabilitation and the conduct or support of evaluations of such projects; (2) training and technical assistance; (3) targeted capacity response programs (4) systems change grants including statewide family network grants and client-oriented and consumer run self-help activities and (5) programs to foster health and development of children; (6) coordination and integration of primary care services into publicly-funded community mental health centers and other community-based behavioral health settings.

This funding opportunity supports research projects that investigate the long-term impacts of disasters on healthcare systems serving vulnerable populations in the U.S., aiming to improve access and reduce health disparities.

This funding opportunity supports U.S.-based small businesses in the clinical validation of biomarkers for neurological or neuromuscular disorders, promoting inclusivity and collaboration while ensuring rigorous scientific standards for potential diagnostic and therapeutic applications.

Reissue of PAR-20-118. This FOA encourages applications to advance the discovery, preclinical development, and proof of concept (PoC) testing of new, rationally based candidate agents and neurostimulation approaches to treat mental disorders, substance use disorders (SUDs) or alcohol use disorder (AUD), and to develop novel ligands and circuit-engagement devices as tools to further characterize existing or to validate new drug/device targets. Partnerships between academia and industry are strongly encouraged. This FOA using the U01 mechanism supports a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies Projects seeking support for a research program of multiple projects directed toward a specific major objective, basic theme or program goal, requiring a broadly based, multidisciplinary and often long-term approach should consider the companion U19 FOA.

This grant provides funding for research studies that explore the relationship between autophagy, HIV infection, and substance use disorders, aiming to uncover mechanisms that could lead to new therapeutic strategies for affected individuals.

This grant seeks to improve health and support services for children, adolescents, youth, and families affected by the HIV epidemic in Eswatini, focusing on prevention, resilience, and sustainable interventions.

This grant provides $7.5 million to local organizations in Madagascar to strengthen public health surveillance, research, and data use, particularly in response to health security threats and outbreaks.