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Grants for Small Businesses

Explore 3,793 grant opportunities available for Small Businesses

Biological Technologies
Contact for amount
DOD-DARPA-BTO (DARPA - Biological Technologies Office)
Federal

Application Deadline

Jun 20, 2024

Date Added

Jun 22, 2023

This announcement seeks revolutionary research ideas for topics not being addressed by ongoing BTO programs or other published solicitations. This publication constitutes a Broad Agency Announcement (BAA) as contemplated in Federal Acquisition Regulation (FAR) 6.102(d)(2) and 35.016 and 2 CFR § 200.203. Any resultant award negotiations will follow all pertinent law and regulation, and any negotiations and/or awards for procurement contracts will use procedures under FAR 15.4, Contract Pricing, as specified in the BAA. BTO's mission is to develop capabilities that leverage the unique properties of biology - adaption, replication, resilience and complexity, to revolutionize how the United States defends the homeland and prepares and protects its Warfighters. Research in BTO creates biotechnological capabilities that provide tactical care and restore function to injured warfighters, increase operational resilience, develop novel functional materials, and detect and protect against threats to maintain force readiness.

Science and Technology
Public and State controlled institutions of higher education
Advanced Laboratories for Accelerating the Reach and Impact of Treatments for Youth and Adults with Mental Illness (ALACRITY) Research Centers (P50 Clinical Trial Optional)
$1,500,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

May 18, 2026

Date Added

Jun 20, 2023

This funding opportunity provides financial support for research centers focused on improving mental health treatments and services for youth and adults in the U.S. through innovative approaches and collaboration among diverse stakeholders.

Health
State governments
Interactive Digital Media (IDM) Biomedical Science Resources for Pre-College Students and Teachers (SBIR) (R43/R44 Clinical Trial Not Allowed)
$295,924
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 26, 2025

Date Added

Jun 15, 2023

This funding opportunity is designed for U.S.-based small businesses to create engaging digital educational tools that teach pre-college students and teachers about biomedical sciences through interactive learning.

Health
Small businesses
ClinGen Genomic Curation Expert Panels (U24 Clinical Trial Not Allowed)
$220,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

May 25, 2025

Date Added

Jun 6, 2023

This funding opportunity provides financial support for research organizations to establish expert panels that will evaluate and curate genomic variants linked to important diseases, enhancing clinical understanding and treatment options.

Education
State governments
NIAID New Innovators Awards (DP2 Clinical Trial Not Allowed)
$300,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 10, 2025

Date Added

Jun 2, 2023

This funding opportunity supports early-stage researchers in the U.S. who are pursuing innovative and high-impact projects in infectious, immunologic, and allergic diseases, without requiring extensive preliminary data.

Health
State governments
NEI Collaborative Clinical Vision Research Project: Resource Center Grant (UG1 Clinical Trial Required)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 25, 2026

Date Added

May 26, 2023

This funding opportunity supports large-scale clinical trials aimed at improving the diagnosis, treatment, and prevention of vision disorders, providing essential resources and services to a wide range of eligible organizations, including universities, nonprofits, and businesses.

Health
State governments
NEI Collaborative Clinical Vision Research Project: Coordinating Center Grant (UG1 Clinical Trial Required)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 25, 2026

Date Added

May 26, 2023

This funding opportunity supports organizations conducting large-scale clinical trials focused on innovative treatments for vision disorders, ensuring effective management and oversight of the research process.

Health
State governments
Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access (X01 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal
Rolling

Application Deadline

Jul 8, 2026

Date Added

May 26, 2023

This grant provides access to advanced genetic and genomic analysis services for research projects focused on understanding genetic factors in human health and disease, without offering direct funding.

Health
State governments
NEI Collaborative Clinical Vision Research: Chair's Grant (UG1-Clinical Trial Required)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 25, 2026

Date Added

May 25, 2023

This funding opportunity supports complex clinical trials aimed at improving screening, diagnosis, prevention, or treatment of vision disorders, targeting researchers and institutions capable of leading high-risk studies with significant public health impact.

Health
State governments
to Publish a Notice of Funding Opportunity (NOFO) for the Rare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network (RDCRN)
$1,000,000
HHS-NIH11 (National Institutes of Health)
Federal

Application Deadline

Jun 14, 2024

Date Added

May 22, 2023

The National Center for Advancing Translational Sciences (NCATS) intends to publish aNotice of Funding Opportunity (NOFO) to solicit applications for research to advance the diagnosis, management, and treatment of rare diseases. Each Rare Diseases Clinical Research Consortium (RDCRC) will promote highly collaborative, multi-site, patient-centric, translational, and clinical research. It is strongly encouraged that the RDCRC study outcome measures include those that address unmet clinical trial readiness needs that will move the field of research forward from its current state. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The NOFO is expected to be published in winter 2024, with an expected application due date in summer 2024. This NOFO will utilize the U54 activity code, which supports specialized centers through multi-project cooperative agreement awards to support research activities with substantial involvement from NIH program staff. Details of the planned NOFO are provided below.

Health
State governments
Chemical Screening and Optimization Facility (X01 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Apr 3, 2026

Date Added

May 19, 2023

This grant provides researchers with access to advanced facilities and technical support for developing non-hormonal contraception and reproductive health products, without direct funding.

Health
State governments
Vet-LIRN Capacity-Building Project and Equipment Grants (U18)
$225,000
U.S. Department of Health and Human Services (Food and Drug Administration)
Federal

Application Deadline

Not specified

Date Added

May 18, 2023

This funding opportunity provides financial support to various organizations, including universities and non-profits, to improve veterinary diagnostic capabilities and address public health issues related to animal food safety and antimicrobial resistance.

Agriculture
State governments
Interventions for Stigma Reduction to Improve HIV/AIDS Prevention, Treatment and Care in Low- and Middle- Income Countries (R01 - Clinical Trial Optional)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Dec 22, 2025

Date Added

May 10, 2023

This funding opportunity supports research projects aimed at reducing stigma related to HIV/AIDS in low- and middle-income countries, with a focus on improving health outcomes for affected populations.

Education
State governments
HIV-associated Non-Communicable Diseases Research at Low- and Middle-Income Country Institutions (R21 Clinical Trial Optional)
$150,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Dec 8, 2025

Date Added

May 10, 2023

This funding opportunity supports research initiatives focused on non-communicable diseases related to HIV at institutions in low- and middle-income countries, encouraging innovative projects and collaborations to improve health outcomes for people living with HIV.

Education
State governments
Division of Chemistry: Disciplinary Research Programs
$105,000,000
National Science Foundation
Federal

Application Deadline

Sep 30, 2026

Date Added

Apr 26, 2023

This funding opportunity supports foundational research in various chemistry subfields for U.S. higher education institutions and nonprofit organizations, promoting advancements in areas like sustainability and advanced manufacturing.

Science and Technology
Public and State controlled institutions of higher education
Innovation for HIV Vaccine Discovery (R01 Clinical Trial Not Allowed)
$350,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 1, 2025

Date Added

Apr 20, 2023

This funding opportunity supports innovative research projects aimed at developing groundbreaking HIV vaccine strategies, encouraging high-risk ideas that diverge from traditional methods and require measurable progress to secure continued funding.

Health
State governments
Developing Regulated Therapeutic and Diagnostic Solutions for Patients Affected by Opioid and/or Stimulants use Disorders (OUD/StUD) (R41/R42 Clinical Trial Optional)
$300,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 14, 2025

Date Added

Apr 18, 2023

This funding opportunity supports small businesses in developing innovative medical products to help treat and diagnose individuals struggling with opioid and stimulant use disorders.

Education
Small businesses
Assay Development and Screening for Discovery of Validated Chemical Hits for Brain Disorders (R01 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 6, 2025

Date Added

Apr 17, 2023

This funding opportunity supports researchers in developing and validating assays to discover new chemical compounds that could lead to treatments for mental health disorders.

Health
State governments
Rural Energy for America Program
$1,000,000
U.S. Department of Agriculture (Rural Business-Cooperative Service)
Federal

Application Deadline

Sep 30, 2024

Date Added

Apr 14, 2023

The Rural Business-Cooperative Service is offering a $1.055 billion grant under the Rural Energy for America Program for qualifying renewable energy and energy efficiency projects, with a maximum grant request of $1 million for renewable systems and $500,000 for energy efficiency improvements.

Energy
Small businesses
Exploratory Clinical Neuroscience Research on Substance Use Disorders (R61/R33 Clinical Trial Optional)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 9, 2025

Date Added

Apr 10, 2023

This funding opportunity supports innovative clinical research to explore the brain mechanisms behind substance use disorders, targeting a wide range of researchers and institutions dedicated to addressing addiction challenges.

Education
State governments

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