Grants for Small Businesses

The purpose of this Funding Opportunity Announcement (FOA) is to facilitate the transition of previously funded SBIR and STTR Phase II and Phase IIB projects in pain management to the commercialization stage by providing additional assistance for private partnering activities through the Commercialization Readiness Pilot (CRP) program. Specifically, this FOA supports the addition of entrepreneurial expertise into small business leadership teams along with supporting partnering activities to aid in commercialization through private third-party funding or partnership with industry.

The purpose of this Funding Opportunity Announcement (FOA) is to 1) invite applications that propose to develop and implement early to late stage clinical trials of promising pharmacological and non-pharmacological interventions for cognitive and neuropsychiatric changes associated with age-related cognitive decline and Alzheimer's disease (AD) and Alzheimer's disease-related Dementias (ADRD) across the spectrum from pre-symptomatic to more severe stages of disease, and 2) stimulate studies to enhance trial design and methods.

This funding opportunity supports institutions that have successfully completed an initial phase of a biomedical research program, enabling them to further develop research capabilities and enhance the careers of early-stage investigators.

Grant Title: Co-infection and Cancer (R01 Clinical Trial Not Allowed) - This grant aims to improve our understanding of how co-infections (excluding HIV) contribute to cancer, particularly in under-studied populations, to identify new prevention and treatment strategies.

This funding opportunity supports collaborative cancer research projects that integrate multiple disciplines and require at least three interconnected research initiatives, aimed at advancing knowledge in cancer biology, prevention, diagnosis, treatment, or control.

This grant provides funding for small-scale cancer research projects that can be completed in two years, aimed at supporting innovative studies and methodologies in various areas of cancer research.

This grant provides funding for researchers to conduct multi-site clinical trials focused on effective treatments and preventive interventions for health issues related to aging, specifically targeting older adults with complex health conditions.

This grant provides funding for researchers and organizations to conduct foundational and applied scientific research that supports the U.S. Army's mission to maintain technological superiority in future conflicts.

This FOA invites applications that propose to develop novel research infrastructure that will advance the science of aging in specific areas requiring interdisciplinary partnerships or collaborations. This FOA will use the NIH Phased Innovation Award (R61/R33) mechanism to provide up to 2 years of R61 support for initial developmental activities and up to 3 years of R33 support for expanded activities. Through this award, investigators will develop a sustainable research infrastructure to support projects that address key interdisciplinary aging research questions.

This FOA invites applications that propose to develop novel research infrastructure that will advance the science of aging in specific areas requiring interdisciplinary partnerships or collaborations.

This Funding Opportunity Announcement (FOA) encourages research grant applications directed toward developing next-generation human cell-derived microphysiological systems (MPS) and related assays that replicate complex nervous system architectures and physiology with improved fidelity over current capabilities. Supported projects will be expected to enable future studies of complex nervous system development, function and aging in healthy and disease states.

This grant provides funding for researchers to develop advanced human cell-based systems that better mimic the complex functions of the nervous system, aiming to improve the understanding and treatment of brain and spinal cord disorders.

The goals of the paleoclimate program are to: (i) provide a baseline for present climate variability and future climate trends, and (ii) improve the understanding of the physical, chemical, and biological processes that influence climate variability and trends over the long-term. Research topics include observational and modeling studies of past climate variability and its drivers and studies that develop new paleoclimate proxies and records. Competitive proposals will address specific aspects of scientific uncertainty for their proposed research. The Paleoclimate program of the Division of the Atmospheric and Geospace Sciences together with other Divisions in the Geoscience Directorate have joined in coordinating and supporting the annual Paleo Perspectives on Present and Projected Climate (P4CLIMATE) competition with the objectives to support studies within two research themes: 1) Past Regional and Seasonal Climate; and 2) Past Climate Forcing, Sensitivity, and Feedbacks. Researchers are encouraged to consider the P4CLIMATE competition as a possible source of support for their global change research. Since proposals eligible for funding in the P4CLIMATE competition are not eligible for funding in the Paleoclimate Program, researchers are strongly advised to contact the Directors of the Paleoclimate Program for guidance as to the suitability of their proposed research for either program. The paleoclimate program strongly encourages proposals from: Researchers at all career stages, including through the AGS Postdoctoral Research Fellowship program. Researchers at all institution types, including MSIs, non-R1 institutions, and institutions in EPSCoR jurisdictions. Researchers from traditionally underrepresented groups in Paleoclimate Science.

This funding opportunity provides financial support to small businesses collaborating with academic or non-profit labs to develop and commercialize innovative technologies and treatments for arthritis, musculoskeletal, and skin diseases.

The Program supports research on the sources, sinks, transport, and transformation of gases and aerosols in the atmosphere through models, observations, and experiments, including homogeneous and heterogeneous chemical reactions, emissions, deposition, atmospheric oxidation and photochemistry, aqueous-phase chemistry and aerosol processes; the formation of new particles and secondary organic aerosols, the modeling of atmospheric chemical processes, the study of chemical mechanisms in the atmosphere, optical properties of gases and aerosols, and improved methods for measuring the concentrations of trace species and their fluxes into and out of the atmosphere.The Program encourages principal investigators from a wide variety of institutions and backgrounds to submit proposals.

This funding opportunity supports innovative medical research projects that enhance the health and readiness of U.S. service members and benefit civilian populations, inviting submissions from a wide range of qualified applicants.

This funding opportunity supports U.S.-based small businesses in developing innovative, non-addictive therapies and technologies for improved pain management, addressing the opioid crisis through preclinical research and technological advancements.

This funding opportunity supports small businesses in developing innovative, non-addictive therapies and technologies for effective pain management, addressing the urgent need for alternatives to opioid treatments.

This funding opportunity supports multidisciplinary teams in developing innovative bioengineering technologies to address specific biomedical challenges, with eligibility for a wide range of organizations including universities, nonprofits, and small businesses.

This funding opportunity supports small research teams in developing innovative biomedical technologies that address critical health challenges and improve healthcare accessibility.