Grants for Nonprofits - Food and Nutrition

This Notice of Funding Opportunity (NOFO) requests applications to explore human pancreatic tissues and the immune compartment for the discovery of specific signaling or processing pathways that may contribute to the asymptomatic phase of T1D, the discovery of early biomarkers of T1D pathogenesis, the development of diagnostic tools for the detection and staging of early T1D in at-risk or recently-diagnosed individuals, and/or the identification and biological validation of therapeutic targets for the development of preventative or early treatment strategies. Successful applicants will join the Consortium on Beta Cell Death and Survival (CBDS), whose mission is to better define and detect the mechanisms of beta cell stress and destruction central to the development of T1D in humans, with the long-term goal of protecting the residual beta cell mass in T1D patients as early as possible in the disease process, and of preventing the progression to autoimmunity. The CBDS is part of a collaborative research framework, the Human Islet Research Network (HIRN, https://hirnetwork.org/), whose overall mission is to support innovative and collaborative translational research to understand how human beta cells are lost in T1D, and to find innovative strategies to protect and replace functional beta cell mass in humans. This NOFO will only support studies with a primary focus on increasing our understanding of human disease biology (as opposed to rodent or other animal models). This NOFO will not accept applications proposing a clinical trial.

Notice of Funding Opportunity Description Background The Food and Drug Administration (FDA) protects the public health by ensuring that medical products intended to be marketed in the United States are safe and effective for their intended use. FDA stakeholders are exploring innovative ways to produce scientific evidence in support of regulatory submissions, including the development of new data sources, study designs, methodologies, and technologies. FDA encourages and facilitates the use of such innovative approaches while ensuring that the scientific evidence supporting marketing approvals meet our high evidentiary standards. The Prescription Drug User Fee Act VII (PDUFA VII) commitment letter represents the product of discussions between the FDA, regulated industry, and public stakeholders, as mandated by Congress. The performance and procedural goals and other commitments specified in the PDUFA VII commitment letter apply to aspects of the human drug review program that are important for facilitating timely access to safe, effective, and innovative new medicines for patients. The commitment letter includes goals relating to the use of digital health technologies (DHTs) to support drug development and review. A DHT is a system that uses computing platforms, connectivity, software, and/or sensors, for health care and related uses. DHTs for remote data acquisition in clinical investigations can include hardware and/or software to perform one or more functions. DHTs may rely on or work with other technologies that support their operation, such as general-purpose computing platforms (e.g., smartphones) and communication networks. Among other activities relating to the use of DHTs, FDA has established a Framework for the Use of DHTs in Drug and Biological Product Development to guide the use of DHT-derived data in regulatory decision-making for drugs (hereinafter Framework ). The Framework highlights FDA’s DHT efforts including workshops and demonstration projects; engagement with stakeholders; establishment of internal processes to support the evaluation of DHTs for use in drug development; promotion of shared learning and consistency regarding DHT-based policy, procedure, and analytic tool development; and publication of guidance documents. In addition, FDA’s webpage DHTs for Drug Development (available at: https://www.fda.gov/science-research/science-and-research-special-topics/digital-health-technologies-dhts-drug-development) provides an overview of the ongoing DHT efforts, including demonstration projects. A variety of project types are welcomed under this NOFO, applicable to drugs and biologics (not devices). FDA is particularly interested in projects that evaluate the use of DHTs in drug development. Project Objectives The overarching goal of this notice of funding opportunity (NOFO) is to explore the role of DHTs (e.g., actigraphy, photography, environmental sensors) in the evaluation of new drugs. These projects may involve engagement with researchers from academia, the biopharmaceutical industry, patient groups, and other stakeholders. The objectives of these projects are to advance DHTs for clinical drug development, expand the ability to capture early manifestations of chronic diseases, determine outcomes in populations with unmet medical needs and enhance convenience for trial participants by allowing for remote data acquisition in clinical investigations. The scope includes, but is not limited to, projects that focus on: Comparing digital measurements to traditional measurements in clinical trials to evaluate drugs Developing and evaluating novel endpoints using DHTs to address unmet needs for drug clinical trials (e.g., use of environmental sensors to capture apnea in pediatric patients) Comparing metrics to evaluate continuous measurements (e.g., maximum activity and stamina) Capturing early manifestations of chronic diseases (e.g., dementia) through the use of DHTs

The Rose Foundation for Communities and the Environment, in partnership with the Bay Foundation of Morro Bay, is offering a grant opportunity through the Central Coast Community-Based Water Quality Grants Program. This initiative focuses on supporting water quality-related projects within the Central Coast Regional Water Quality Control Board’s jurisdiction. The program's core mission aligns with the Rose Foundation's broader goals of fostering environmental health and community well-being, specifically by addressing critical water issues in California's Central Coast. The program primarily targets projects that advance environmental justice and provide water quality benefits to underrepresented communities. This focus aims to address historical inequities and ensure that all communities have access to clean and safe water. The expected outcomes include tangible improvements in water quality, enhanced environmental justice outcomes, and increased resiliency for communities facing water-related challenges. Measurable results will likely involve reductions in pollutant loading, progress toward water quality objectives, and the preservation and restoration of watershed functions. Key priorities and preferred topic areas for this grant include the human right to water, environmental justice capacity building, and understanding the water quality impacts of climate change. The program also emphasizes drought-related water supply resiliency, climate adaptation and mitigation, sustainable drinking water and wastewater treatment, and sustainable groundwater management strategies. Additionally, projects that benefit marine habitats in San Luis Obispo County, reduce pollutant loading to meet Central Coast Basin Plan objectives, restore impaired waterbodies, implement on-farm Best Management Practices to reduce salt and nitrate, and prevent or address Harmful Algal Blooms are highly encouraged. The grant offers two funding tracks: a Large Grant Track for requests up to $200,000 (with most awards between $100,000-$200,000) and a Small Grant Track for requests up to $50,000 (with most awards between $20,000-$50,000). Eligible applicants include 501(c)(3) nonprofit organizations, federally recognized and State Indian tribes, and public agencies with jurisdiction over water resources management. All projects must be conducted within the Central Coast Water Board's Region 3 jurisdiction, encompassing Southern Santa Clara, Santa Cruz, San Benito, Monterey, San Luis Obispo, Santa Barbara, and portions of Ventura, Kern, and San Mateo Counties. The foundation's strategic approach underscores a commitment to community-driven solutions and measurable environmental impact through collaborative partnerships.

The Permanent Commission on the Status of Racial, Indigenous, and Tribal Populations (the Permanent Commission) is offering grants to develop and implement programs that address social drivers of health (SDOH) and build stronger community connections. This initiative aligns with the Commission's statutory mandate to improve public health outcomes, especially for racial, Indigenous, and tribal populations who have historically faced disproportionate chronic health and disease impacts, further exacerbated by the COVID-19 pandemic. The grant program aims to deepen the Commission's relationships with Community-Based Organizations (CBOs) and community leaders, invest resources directly in Maine communities severely impacted by COVID-19, and support innovative community-led approaches to addressing SDOH. The target beneficiaries of this program are communities located within Maine, particularly those with racial, Indigenous, and tribal populations that have been historically marginalized and disproportionately affected by health disparities, especially during the COVID-19 pandemic. The impact goals include improving public health outcomes, increasing social capital, and fostering stronger community connections within these communities. This program recognizes that persistent disparities in SDOH require targeted and community-driven solutions to achieve equitable health and well-being. The program prioritizes supporting CBOs in creating new and innovative community-led approaches to addressing SDOH for their communities. A key focus is on increasing social capital in historically marginalized communities by supporting community-building activities within Maine. Eligible applicants must be CBOs as defined by the RFA, meaning they are driven by and accountable to the community they serve, have a physical presence, and include community perspectives in determining priority issues and solutions. Proposed projects must specifically benefit communities within Maine. Expected outcomes include the establishment of stronger relationships between the Permanent Commission and CBOs/community leaders, direct investment of resources into severely impacted Maine communities, and the successful implementation of new, innovative, community-led initiatives addressing SDOH. Measurable results will likely involve tracking the number of CBOs partnered with, the reach of the programs, and indicators related to improved SDOH outcomes and increased social capital within the targeted communities. The total grant funding for this program is $300,000, with applicants able to apply for a minimum of $25,000 and a maximum of $75,000 over a contract period not exceeding 18 months or extending beyond December 2025. This funding supports the Commission's strategic priority of addressing health equity through community empowerment and direct resource allocation.

This program provides funding to Illinois-based nonprofits, educational institutions, and government entities to enhance the specialty crop industry, focusing on food safety, research, and support for underserved farmers.

The Four County Community Foundation (4CCF) is launching its Spark Grant Program, designed to offer a more accessible and interactive grant application experience than traditional processes. This program aligns with the 4CCF's mission by focusing on funding innovative projects that address unmet community needs within its service area. The foundation aims to foster community development and empower local initiatives through this streamlined grant format, ensuring that vital projects receive the support they require to make a tangible difference. The Spark Grant Program targets a broad range of beneficiaries, including both individuals and nonprofit groups, who are actively working to meet community needs. The program's impact goal is to support truly innovative projects that can demonstrate a clear benefit to the local community. An example of a past successful project includes a partnership between a Shelby Township-based business and the Hispanic Service Center, offering reduced-cost Spanish-language food safety training, which met a critical need for local entrepreneurs. This illustrates the foundation's commitment to supporting diverse and impactful initiatives. The program prioritizes proposals that are innovative and seek to address an unmet community need within 4CCF’s service area. The selection process involves applicants presenting an in-person proposal to a panel of 4CCF committee members, followed by a five-minute question and answer session. This interactive approach emphasizes transparency and direct engagement, allowing the foundation to better understand the proposed projects and their potential impact. With a pool of $50,000 to award, the Spark Grant Program expects measurable outcomes in community development and the support of local entrepreneurs, particularly those from underrepresented groups. The example of the Spanish-language food safety training highlights the potential for projects to address specific demographic needs and foster economic empowerment. The foundation's strategic priority is to identify and invest in initiatives that demonstrate creativity and a direct, positive impact on the well-being and growth of the four-county community, reflecting a theory of change that values accessible support for innovative local solutions.

This funding opportunity supports innovative research that investigates how aging affects individuals living with HIV, focusing on improving their health outcomes and addressing related challenges.

This funding opportunity provides financial support for innovative healthcare projects aimed at improving services and access for underserved populations in Tennessee's rural counties.

This funding opportunity supports innovative, interdisciplinary research projects that aim to fill critical knowledge gaps and advance scientific understanding in areas related to kidney, diabetes, and digestive diseases.

This funding opportunity supports students enrolled in dual-degree medical and research training programs, helping them develop into independent physician-scientists through mentored research and clinical training.

This funding opportunity supports community-based nonprofit organizations that address health disparities and improve access to healthcare for historically marginalized populations.

This funding opportunity provides financial support to neighborhoods, community groups, and local businesses in Marysville, Washington, for projects aimed at beautifying their local areas.

This grant provides funding to nonprofit organizations and government entities within the UDS 260 area for innovative community projects that enhance local well-being.

This funding opportunity supports clinical trials aimed at developing new therapies for rare neurodegenerative diseases, such as ALS, and is open to a wide range of eligible organizations, including universities and nonprofits.

The PeopleFund's BIPOC Small Business Accelerator is a program designed to empower underserved entrepreneurs in Texas. It provides capital, education, and resources to foster healthy business growth among its participants. PeopleFund's mission is aligned with this program by directly addressing the financial and educational gaps faced by BIPOC (Black, Indigenous, and People of Color) business owners, a critical component of economic equity and community development. The program emphasizes practical support through a structured curriculum and ongoing mentorship. The program targets BIPOC entrepreneurs located in Texas, specifically those who are in low to moderate-income areas, or whose individual address or household income falls within these classifications. It is open to both start-up and existing businesses that demonstrate the ability to support a loan payment through available global cash flow and meet PeopleFund's credit and lending qualifications. This focus ensures that the program reaches individuals and businesses most in need of support to overcome systemic barriers to business success. Key priorities of the accelerator include providing access to business planning software like LivePlan, an online curriculum, and expedited loan packaging and application support. Participants commit to an orientation, virtual training sessions, and assigned "homework," demonstrating a dedication to their business development. The program also prioritizes ongoing after-care through dedicated business coaching and mentorship, recognizing that sustained support is crucial for long-term growth and success. Expected outcomes and measurable results include participants qualifying for a PeopleFund loan product, completion of a business plan, financial statements, and a capital portfolio. They are also expected to gain access to business and professional resources, tools and technology, and networking opportunities within their cohort. The program aims to increase the number of successful BIPOC-owned businesses in Texas, thereby contributing to local economic growth and reducing wealth disparities. The grant amount ranges from $3,000 to a maximum of $5,000. The program's strategic priorities are centered on fostering self-sufficiency and sustainable growth for BIPOC entrepreneurs. PeopleFund's theory of change posits that by providing targeted capital, comprehensive education, and continuous mentorship, they can equip underserved business owners with the essential tools and knowledge to not only start but also significantly scale their businesses. This approach is designed to create a ripple effect, leading to job creation, increased local economic activity, and enhanced community resilience.

The Neighborhood Beautification Grant (NBG) initiative, a component of the City's Community Partnerships & Engagement Division (CPED), is designed to engage and encourage residents to work with their neighbors on enhancement and improvement projects. The core mission of NBG is to promote healthier, safer, and cleaner neighborhoods, while simultaneously strengthening community connections and the social fabric within them. The City Council has approved an allocation of $42,000 for these beautification projects, distributed equally at $6,000 to each Council District and the Mayor's office. The NBG targets a broad range of beneficiaries including any resident, group, and/or organization with a new or established community project in Salinas. Specifically, residents, community-led groups, advocacy groups, art organizations, apartment or community associations, and neighborhood watch groups are encouraged to apply. The impact goals are centered around cultivating healthy and resilient neighborhoods, supporting engaged and informed residents, stimulating a thriving community, and properly managing shared assets and spaces. The ultimate aim is to achieve a collective impact in the development of neighborhood communities and service delivery strategies to improve the overall quality of life in Salinas. The program prioritizes projects that can be completed within the established timeline, promote neighborhood self-help efforts, and foster neighborhood improvement and beautification. Furthermore, projects must provide health and safety benefits, have confirmed neighborhood support, be visible and accessible to all city residents, and address a specific neighborhood need. Eligibility also requires that group projects focus on beautification, restoration, neighborhood improvements, fostering neighborhood leadership, or addressing neighborhood problems, with each group including at least five volunteers or members. The expected outcomes and measurable results of the NBG initiative include tangible improvements in neighborhood aesthetics, safety, and community engagement. By supporting projects that are visible and accessible to all city residents, the program aims to create a widespread positive impact. The emphasis on confirmed neighborhood support and self-help efforts suggests a theory of change that empowers communities to drive their own improvements, leading to more sustainable and impactful results. While the document does not explicitly detail the foundation's strategic priorities or theory of change beyond the NBG's objectives, the program's design implicitly aligns with strategies that foster civic participation, local ownership, and community-led development for urban betterment.

The Texans Feeding Texans Home-Delivered Meal Grant Program aims to supplement and extend current home-delivered meal programs for seniors and/or disabled Texans. Eligible entities include governmental and non-profit agencies. The program involves counties making qualifying grants to meal providers based on a rate of $0.25 per county senior as reported in the 2020 census. Meal providers must receive a grant from the county, deliver meals to homebound elderly or disabled individuals, and complete a required application. The Texas Department of Agriculture facilitates the funding process.

The Animal Services Responsive Grant, offered by the San Antonio Area Foundation, aims to improve the quality of life for all animals, educate the community on responsible pet care, and enhance spay/neuter and adoption services. This aligns with the foundation's broader mission to support vital community needs, ensuring that organizations dedicated to animal welfare receive the necessary funding to operate and expand their reach. By focusing on these key areas, the grant seeks to create a more humane environment for animals and foster responsible pet ownership within the community. The primary beneficiaries of this grant are animals in need, as well as the communities and individuals who benefit from enhanced animal welfare services. The grant targets organizations working in specific Texas counties: Atascosa, Bandera, Bexar, Comal, Guadalupe, Kendall, Medina, and Wilson. The impact goals are centered on reducing animal suffering, increasing pet adoptions, promoting spay/neuter initiatives to control pet overpopulation, and educating the public on best practices for animal care. The grant prioritizes nonprofit organizations that demonstrate a clear commitment to these objectives and have a proven track record of serving their local animal populations. The program's priorities include supporting direct animal care services, public education campaigns, and programs that facilitate adoption and spay/neuter. The expected outcomes are a measurable reduction in the number of homeless and neglected animals, an increase in responsible pet ownership, and a more informed community regarding animal welfare issues. Measurable results are tied to the organizational budget and corresponding award amounts, indicating that larger, more established organizations with greater capacity are expected to achieve more significant outcomes. For instance, organizations with budgets over $1,000,000 are eligible for a $50,000 award, implying an expectation of broader impact. The San Antonio Area Foundation's strategic priorities, as demonstrated by this grant, include fostering community well-being through targeted support for critical services. Their theory of change appears to be that by providing financial resources to qualified animal welfare organizations, these organizations will be empowered to implement effective programs that directly address the root causes of animal neglect and overpopulation, ultimately leading to a healthier and more compassionate community for both humans and animals. The eligibility criteria, such as requiring 501(c)(3) status and local operation, ensure that funding is directed to legitimate and impactful entities. This grant does not support endowments, capital campaigns, religious purposes, scholarships, political activities, or lobbying efforts. This restriction further refines the foundation's strategic focus, ensuring that funds are directly applied to programmatic efforts that align with the core goals of animal services. The focus is strictly on responsive grants that address immediate and ongoing needs, rather than long-term institutional building or advocacy.

The Arts & Culture Capacity Building Grant Program, offered by the City of Dubuque, is designed to support initiatives that foster more sustainable and effective arts and culture organizations within the city. This program aligns with a mission to strengthen the operational capacity of local arts and culture entities, ensuring their long-term viability and ability to contribute to the community. Funding is available for fiscal year 2025, from July 1, 2024, through June 30, 2025, with a total of $35,000 allocated for grants ranging from $1,000 to $10,000, although eligible organizations can apply for up to $8,000. The primary beneficiaries of this grant program are arts and culture organizations that are nonprofit 501(c)(3) organizations, have at least two years of programming documentation and two Form 990s, and are officially located within the city limits of Dubuque. These organizations must serve residents of Dubuque and conduct programming within the city. The program aims to impact these organizations by enhancing their capacity in various key areas, ultimately leading to improved organizational health and effectiveness. The program prioritizes a range of capacity-building initiatives. These include strategic planning, creating development plans and/or fundraising strategies, improving donor experience, providing nonprofit 101 training for staff and board members, leadership development, project or program development, program management, volunteer management, and Diversity, Equity, Accessibility, and Inclusion (DEAI) training. These focus areas are intended to address common challenges faced by arts and culture organizations and equip them with the tools and knowledge needed to thrive. Expected outcomes include organizations with stronger strategic frameworks, enhanced fundraising capabilities, improved donor engagement, more skilled staff and board members, and more effectively managed projects and programs. Measurable results would involve the successful implementation of these capacity-building initiatives, which could be tracked through reports detailing new strategic plans, implemented fundraising strategies, attendance at training sessions, and improved operational metrics. The City of Dubuque's strategic priorities for this grant program appear to be rooted in a theory of change that by investing in the foundational and operational strength of its arts and culture sector, it will foster a more vibrant, resilient, and inclusive cultural landscape for its residents.

This funding opportunity supports research initiatives focused on non-communicable diseases related to HIV at institutions in low- and middle-income countries, encouraging innovative projects and collaborations to improve health outcomes for people living with HIV.