Grants for Nonprofits - Science and Technology

The West Haven ARPA Grant, administered by The Arts Council of Greater New Haven (ACGNH) in partnership with ArtsWest CT, aims to rapidly stimulate arts and culture activity in West Haven, CT. With $116,250 of ARPA funds from the City of West Haven, the program seeks to distribute microgrants of $2,500-$10,000 to artists, arts organizations, and creative businesses within the city. This initiative aligns with the ACGNH's mission to support and foster arts and culture within the greater New Haven area, extending its reach to West Haven to ensure a vibrant creative economy and community engagement. The target beneficiaries for these microgrants are individuals over 18 years of age, or organizations/collectives with a representative over 18, who are either based in West Haven or proposing a project that directly serves the West Haven community. The primary impact goal is to stimulate artistic, historical, and/or culturally-specific activities within West Haven during the project period of July-August 2024. The program prioritizes proposals that demonstrate feasibility and can be easily executed within the short timeframe, with a strong emphasis on projects that foster equity and inclusion, and strengthen community ties within West Haven. The grant focuses on two main categories for the use of funds: General Operating Support (GOS) and Project Support. GOS includes expenses like rent, equipment purchases/rentals, subscriptions, printing/mailing, and contract labor (e.g., graphic designers, consultants). Project Support covers physical materials, ground transportation, commissions, contract labor (e.g., performers, consultants, designers), advertising, and venue rental. Notably, expenses for salaried employees paid via payroll (W-2 employees) are not eligible, and recipients will receive a 1099, responsible for their own income taxes. Expected outcomes include a rapid increase in arts and culture activities within West Haven during the summer of 2024, with measurable results tied to the feasibility, equity, and community impact of the funded projects. The evaluation criteria, Feasibility, Equity + Inclusion, and Community, are designed to guide applicants towards projects that are not only achievable within the project period but also actively incorporate, serve, and support historically marginalized residents and activate and elevate the broader West Haven community through partnerships. This strategic approach reflects a theory of change where targeted financial support, with an emphasis on local engagement and accessible execution, leads to a flourishing local arts scene and enhanced community well-being.

This funding opportunity supports nonprofit organizations and destination marketing groups in Fairfield County, South Carolina, to develop projects that attract tourists and boost the local economy through targeted advertising and enhanced recreational and cultural experiences.

This grant provides funding to U.S.-based nonprofit organizations and for-profit businesses to help foreign governments adopt secure American digital technologies, enhancing their cybersecurity and infrastructure capabilities.

This program provides funding to various organizations and government entities in Utah to improve access to high-speed internet, affordable devices, and digital skills training for residents, aiming to bridge the digital divide across the state.

The 2025 Sea Scallop Research Set Aside Program is a grant that awards scallop quota to successful applicants for conducting research to enhance knowledge about the scallop fishery resource and contribute to scallop management decisions, with funding generated from the sale of the awarded quota.

The White Family Foundation, a fund of the Community Foundation of Hancock County, aims to bolster local community development in Hancock and Henry counties, Indiana. This grant program is designed to support initiatives that enhance the quality of life, making these areas more desirable places to live, work, and play. The foundation's mission is directly aligned with fostering community growth and well-being within these specific regions. The grant program targets a broad range of beneficiaries, including tax-exempt 501(c)(3) organizations, mutual benefit organizations, government agencies, municipalities, and churches that serve Hancock and/or Henry counties. The primary impact goal is to create more vibrant and sustainable communities. The foundation prioritizes projects that fall under several key focus areas. These include beautification projects, building façade improvements, enhancements to recreational facilities and accessibility, and initiatives related to public safety and transportation. These priorities reflect a strategic approach to addressing various facets of community development that contribute to a higher overall quality of life. While specific measurable results are not detailed in the provided information, the expected outcomes are clear: improved community aesthetics, enhanced recreational opportunities, safer public spaces, and more efficient transportation networks within Hancock and Henry counties. The foundation's strategic priorities are rooted in a theory of change that posits by investing in these diverse areas of community infrastructure and social programs, the overall desirability and functionality of the counties will increase, leading to a more engaged and thriving populace.

The City of Bellevue is requesting proposals for Community Development Block Grant (CDBG) funding, estimated at $1,000,000 in PY2025 funds. This program seeks to support non-construction Capital projects, such as architectural and engineering costs, single-family home rehabilitation, weatherization, acquisition or pre-acquisition costs, and Economic Development projects, specifically microenterprise business assistance. The program aligns with a mission to improve community infrastructure and economic opportunities, while not focusing on public services like homeless services or food banks at this time. The target beneficiaries include residents and businesses within Bellevue who would benefit from improved housing, community facilities, and economic development opportunities, particularly through microenterprise support. The impact goals are to enhance the physical and economic well-being of the community through strategic investments in capital projects and business development. This contributes to the broader community development objectives set forth by the City of Bellevue and HUD. The City's priorities include funding projects that comply with U.S. Department of Housing & Urban Development (HUD) CDBG program regulations (24 CFR Part 570). Specific focuses include the acquisition of real property, pre-acquisition costs, design-related and other soft costs for non-construction projects, acquisition/rehabilitation of public facilities, home repair/rehabilitation, maintenance, weatherization activities, and microenterprise business assistance and development. Nonprofit organizations or public agencies are eligible to implement these projects, with a preference for those with a verifiable history of receiving and administering funds from HUD. Expected outcomes include improved housing conditions for single-family homes through rehabilitation and weatherization, enhanced public facilities, and increased economic stability through microenterprise development. Measurable results could include the number of homes rehabilitated, public facilities improved, new microenterprises supported, and jobs created or retained through economic development initiatives. The City makes no guarantees regarding funding availability, as it is dependent on the 2025 federal CDBG budget and other factors. Projects selected will be part of the 2025-2029 CDBG Consolidated Plan, indicating a long-term strategic approach to community development.

This grant opportunity, offered by Sanofi, aims to address gaps and provide educational resources related to the diagnosis and treatment of Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP). CIDP is a heterogeneous, immune-mediated neuropathy characterized by demyelination of motor and sensory nerves, leading to various clinical challenges. Sanofi seeks proposals for educational programs, particularly those that can effectively recap information from the 2024 Peripheral Nerve Society Annual Meeting and offer independent medical education (IME) activities. Programs should focus on key evidence-based data and offer recommendations to healthcare providers dealing with CIDP, particularly in areas such as treatment options, clinical challenges, and the role of complement therapeutics in CIDP care.

The City of Shreveport, through its Department of Community Development, has announced a Notice of Funding Availability (NOFA) for Affordable Rental Housing Proposals. This initiative is primarily funded by the HOME Investment Partnerships Program American Rescue Plan (HOME ARP). The core mission of this grant program is to address the critical need for affordable housing within the community by soliciting proposals from experienced agencies dedicated to developing and managing such properties. This aligns with a broader strategic priority to enhance housing stability and accessibility for vulnerable populations. The primary beneficiaries of this program are individuals and families from specific qualifying populations. These include people experiencing homelessness, those at risk of homelessness, individuals fleeing or attempting to flee domestic violence, dating violence, sexual assault, stalking, or human trafficking, and other populations where supportive services would prevent homelessness or serve those with the greatest risk of housing instability. The impact goal is to provide safe, stable, and affordable rental housing, thereby reducing homelessness and housing insecurity for these vulnerable groups. The program's priorities and focuses revolve around the production or preservation of affordable housing through new construction, rehabilitation, and property acquisition, including vacant land, specifically for HOME-ARP rental housing projects. These projects must commit to providing affordable rental housing for a minimum of 15 years. The City of Shreveport aims to fund up to three qualified entities that demonstrate extensive experience in affordable housing development, non-congregate or transitional housing operations, supportive service programs, and federal policy compliance. Expected outcomes include an increase in the number of available affordable rental housing units in Shreveport, directly benefiting the identified qualifying populations. Measurable results will likely include the number of new units constructed or rehabilitated, the number of individuals and families housed, and the duration of their housing stability. The City's strategic priority is to leverage federal funding to create a sustainable impact on housing affordability, with a theory of change that posits that by investing in experienced developers to create and preserve affordable housing, they can directly mitigate the effects of housing instability and homelessness in the community.

This grant provides funding for research and development projects focused on advancing air superiority technologies, targeting educational institutions, non-profit organizations, and private industry involved in armament technology.

The Community Impact Grants program, offered by the Community Foundation of Greater Dubuque, is designed to award grants from unrestricted funds to improve policies and practices within the Greater Dubuque community. The core mission of this program is to achieve the greatest possible impact through strategic investments. This aligns with the Foundation's broader goal of fostering positive change and strengthening the region by supporting initiatives that address critical community needs and enhance overall well-being. The program primarily targets nonprofit 501(c)3 organizations, churches, schools, or government organizations that provide services in Clayton, Clinton, and Dubuque counties. Organizations without 501(c)3 status are encouraged to find a qualifying fiscal sponsor. The overarching impact goal is to support capacity-building efforts among these nonprofits, thereby empowering them to deliver more effective and sustainable services to the community. This focus on capacity building aims to create a stronger, more resilient network of organizations serving the region. Project proposals for Community Impact Grants can focus on a variety of areas, demonstrating the program's broad priorities. These include community programming, individual and team leadership development, organization-wide planning and development, equity, diversity and inclusion initiatives, network development, communications, evaluation and learning planning, and digital and physical security. These diverse focus areas reflect the Foundation's strategic commitment to addressing a wide range of needs that contribute to a healthy and thriving community. While specific measurable results are not explicitly detailed, the emphasis on capacity-building efforts and the various project focus areas imply expected outcomes such as enhanced organizational effectiveness, improved leadership capabilities, more inclusive practices, stronger community networks, better communication strategies, and increased ability to assess and learn from program impacts. By supporting these areas, the Community Foundation of Greater Dubuque operates on a theory of change that by strengthening the infrastructure and capabilities of local nonprofits, it will ultimately lead to a more impactful and sustainable benefit for the residents of Clayton, Clinton, and Dubuque counties.

The Crookston Area Community Fund (CACF), under the umbrella of the Northwest Minnesota Foundation, offers grants to support charitable, educational, and public purpose projects. These projects are specifically designed to enhance or improve the quality of life for both residents and visitors within the Crookston area. This grant program aligns directly with the foundation's mission to foster community well-being and development in Northwest Minnesota. The primary beneficiaries of this grant program are nonprofit organizations and public agencies operating in the Crookston area. The program aims to support projects that address key community needs and contribute to a better quality of life. Impact goals include fostering improvements in education, stimulating economic development, bolstering healthcare services, protecting the environment, enhancing recreational opportunities, and supporting cultural and community service initiatives. The CACF prioritizes projects that fall under specific topics: education, economic development, healthcare, environment and recreation, and cultural and community service. These focus areas represent critical sectors where strategic investment can lead to significant community benefits. The selection process considers how effectively proposed projects address these areas and their potential for positive, tangible outcomes. Expected outcomes include measurable improvements in the quality of life across the Crookston area. Projects should demonstrate clear objectives and the potential for a positive impact on the community. While specific measurable results are not detailed in the provided text, the emphasis on enhancing and improving quality of life suggests that successful projects will lead to concrete benefits, such as improved access to educational resources, new economic opportunities, better health outcomes, or increased engagement in cultural and recreational activities. The program plans to award a total of $25,000 in this grant round, with individual grants ranging from $500 to $10,000.

The CHIPS Research and Development Program (CHIPS R) aims to advance the development of semiconductor technologies and to enhance the competitiveness of the U.S. semiconductor industry. This is the first Notice of Funding Opportunity under this program. It seeks applications for new research and development (R) activities to establish and accelerate domestic capacity for advanced packaging substrates and substrate materials, a key technology for producing microelectronics systems. This NOFO seeks applications for research and development activities that will establish and accelerate domestic capacity for advanced packaging substrates and substrate materials. Through this NOFO, the NAPMP program seeks to achieve the following objectives: (1) Accelerate domestic R&D and innovation in advanced packaging materials and substrates; (2) Translate domestic materials and substrate innovation into U.S. manufacturing, such that these technologies are available to U.S. manufacturers and customers, including to significantly benefit U.S. economic and national security; (3) Support the establishment of a robust, sustainable, domestic capacity for advanced packaging materials and substrate R&D, prototyping, commercialization, and manufacturing; and (4) Promote a skilled and diverse pipeline of workers for a sustainable domestic advanced packaging industry. NAPMP plans to release subsequent NOFOs relevant to other research areas and for an Advanced Packaging Piloting Facility (APPF), where successful development efforts will be transitioned and validated for scaled transition to U.S. manufacturing. The APPF is expected to be a key facility for technology transfer to high-volume manufacturing.

The Pennsylvania Council on the Arts (PCA) is currently accepting applications for the 2024-2025 Creative Sector Flex Fund (CSFF). This grant program aims to provide flexible support to eligible applicants that offer consistent annual artistic programming and/or arts services within Pennsylvania. The fund is designed to bolster the administrative, programmatic, and project-related expenses of arts organizations, aligning with the PCA's mission to support and strengthen the arts community across the state. This initiative reflects the PCA's strategic priority of fostering a vibrant and sustainable creative sector by providing direct financial assistance where it's most needed. The primary beneficiaries of the CSFF are nonprofit, tax-exempt corporations, or units of local government in Pennsylvania that demonstrate a history of at least two years of consistent arts programming. Pre-K-12 public, private, and parochial schools are not eligible, but are directed to other PCA opportunities. The fund targets organizations with an annual average arts revenue between $10,000 and $200,000. The impact goal is to ensure the continued delivery of artistic programming and services to communities throughout Pennsylvania, thereby enriching the cultural landscape and supporting the economic viability of the arts sector. The program prioritizes flexibility, allowing funds to be used for a wide range of needs, including administrative costs, program development, and specific project expenses. This approach is rooted in the understanding that a resilient arts sector requires adaptable support. While annual grants are not guaranteed and are dependent on the PCA's budget, the expected outcome is that successful applicants will be able to maintain or expand their artistic offerings, reach broader audiences, and continue to contribute to the cultural and economic well-being of Pennsylvania. Measurable results would include the number of organizations supported, the scope and reach of the artistic programming delivered, and the overall stability of the recipient organizations. By investing in these entities, the PCA's theory of change posits that targeted financial support will lead to a more robust, diverse, and accessible arts environment, ultimately benefiting all Pennsylvanians. The project period for this grant is January 1, 2025 – December 31, 2025, with a grant size ranging from $1,000 to $10,000, typically set at $5,000 per applicant.

The Community Foundation for Northeast Florida is offering Small Arts Organization Grants to support small and mid-size arts and cultural organizations in the Northeast Florida region. This funding aims to enhance organizational capacity-building and program development within the arts and culture sector. The foundation's mission, as evidenced by this grant, aligns with fostering a vibrant cultural landscape in the region by investing in the growth and stability of local arts organizations. The target beneficiaries of this grant are small to mid-sized arts and cultural organizations with current 501(c)(3) status or a formal fiscal sponsorship agreement, along with a minimum two-year work history. These organizations must be primarily focused on arts and culture and be based in Baker, Clay, Duval, Nassau, Putnam, or St. Johns County, Florida. The impact goals are to strengthen these organizations, enabling them to expand their reach, improve their programs, and contribute more effectively to the cultural enrichment of their communities. The grant prioritizes initiatives that focus on organizational development and program enhancement, providing funding between $1,000 and $10,000. This focus suggests a strategic approach by the Community Foundation to not only fund individual projects but also to build the long-term sustainability and effectiveness of arts organizations. By strengthening the foundational capacity of these groups, the foundation aims to create a more robust and resilient arts ecosystem in Northeast Florida. Expected outcomes include improved operational efficiency, expanded programming, and increased community engagement by recipient organizations. While specific measurable results are not detailed in the provided text, the emphasis on capacity-building and program development implies a focus on quantifiable improvements in these areas, such as increased audience participation, diversified funding streams, or the development of new and impactful artistic programs. This strategic funding approach reflects the Community Foundation for Northeast Florida's theory of change, which posits that investing in the foundational strength of arts and cultural organizations leads to greater community benefit and a richer cultural environment.

The Entergy Charitable Foundation, in partnership with the NFL Foundation and other key organizations, is spearheading the Super Bowl LIX Legacy Program, "Impact 59 Powered by Entergy." This initiative aims to leave a lasting legacy of philanthropy and economic impact within the Greater New Orleans community, aligning with Entergy's broader mission of community support and development. The program's strategic approach focuses on fostering positive change through collaborative efforts with local nonprofit partners, reflecting a commitment to leveraging significant events like the Super Bowl for long-term community benefit. The primary target beneficiaries of the "Impact 59" grants are underserved populations within ten specific parishes in Louisiana: Orleans, Jefferson, St. Bernard, St. Charles, St. James, St. John the Baptist, Plaquemines, St. Tammany, Tangipahoa, and Washington. The program aims to achieve significant impact in several key areas, including Youth Development, Workforce Training, Education, Health & Wellness, and Equity & Inclusion. The overarching goal is to enhance the quality of life, increase opportunities, and promote a more equitable environment for marginalized individuals and groups within these communities. The program's priorities and focuses are clearly defined. In Youth Development, the emphasis is on mentoring, physical and mental well-being, and engaging youth through sports, health clinics, and specialized training. Workforce Training focuses on increasing employability for underserved populations, including the formerly incarcerated, to secure living wage jobs. Education seeks to improve access to quality education through contemporary learning programs. Health & Wellness aims to enhance access to services for underserved communities, supporting health, nutrition, and food programs. Finally, Equity & Inclusion is dedicated to improving experiences for marginalized individuals and guaranteeing fair treatment, access, opportunity, and advancement for all. Expected outcomes include a minimum of $3 million in grants distributed to local nonprofit partners. Grants will range from $25,000 to $250,000, with smaller organizations (under $500,000 annual budget) eligible for $25,000 to $50,000, and larger organizations receiving up to $250,000. Measurable results will stem from the impact of funded programs in addressing the identified focus areas, contributing to a legacy of improved community well-being and economic empowerment. The foundation's theory of change posits that by strategically investing in these critical areas through local nonprofits, they can create a ripple effect of positive societal transformation, ultimately building stronger, more resilient communities in the Greater New Orleans area.

The DC Commission on the Arts and Humanities (CAH) is offering a grant program to support the development and public presentation of visual art exhibitions. This initiative aligns with CAH's mission to foster artistic and cultural development within the District of Columbia by providing opportunities for local artists and curators. The grant aims to enhance the cultural landscape of D.C. through innovative and educational art exhibitions, utilizing CAH's exhibition space and virtual platforms. The primary target beneficiaries of this grant are District resident curators and nonprofit organizations with curatorial capacity. The program seeks to empower these individuals and groups to develop and present compelling visual art exhibitions. The impact goals include providing opportunities for D.C. resident curators to showcase new works or bring existing exhibitions from other cities to the District, thereby enriching the cultural experiences available to local residents. The program prioritizes fostering innovative and educational art exhibitions. Key focus areas include supporting the presentation of visual art in a government facility and offering unique exhibitions and related programs for District residents. Expected outcomes include an increase in the number and diversity of art exhibitions available in D.C., greater visibility for local curators and artists, and enhanced engagement of District residents with the arts. Funding for individuals and new nonprofit organizations in FY25 can be up to $30,000, or $35,000 if working with a co-curator or curatorial mentee, with a grant period from October 1, 2024, to September 30, 2025. Eligibility criteria for individuals include being an artist, curator, or arts-related professional over 18 with prior curatorial experience, maintaining D.C. residency, and being in good standing with CAH. Nonprofit organizations must be 501(c)(3) certified, have a principal business office in D.C., be registered to do business in the District, ensure at least 51% of activities occur in D.C., and obtain Citywide Clean Hands certification. Colleges, universities, service organizations, foreign governments, and other DC/Federal Government agencies are ineligible.

This grant provides funding and technical assistance to organizations that help state, local, and Tribal governments improve their planning and permitting processes for large-scale renewable energy projects.

The North Central Region SARE (NCR-SARE) Research and Education (R&E) Grant Program is a competitive funding opportunity offering $100,000 to $500,000 for up to 3 years to researchers, educators, and organizations exploring sustainable agriculture, with the aim of improving economic viability, environmental quality, and quality of life in the North Central Region's agricultural sector.

Orthopaedic injuries have a profound impact on military readiness and return to work/activity/duty. In the military, extremity battle wounds comprise approximately 50% of injuries reported in the Department of Defense Trauma Registry. Additionally, orthopaedic injuries and conditions that occur outside of combat (e.g., during training, leisure activities, resultant from old injuries) present one of the greatest threats to the readiness of our Service Members and military. Early stabilization, treatment, and rehabilitation of orthopaedic injuries in both civilian and military populations have led to better outcomes, particularly in the prevention of secondary complications and in minimizing morbidity. Availability of orthopaedic care and treatment as early as possible, or as close to the point of injury as possible, also minimizes limb loss and affects military readiness.Although the PRORP is interested in supporting military-focused research, research supported by the PRORP is expected to also apply to all individuals who have sustained a major orthopaedic injury.With the initiation of the Arthritis Research Program, the FY24 PRORP may not fund arthritis research; however, research that addresses conditions or health abnormalities related to arthritis is permitted provided the proposed research addresses the selected Focus Area.The PRORP CTA supports the rapid implementation of clinical trials with the potential to have a significant impact on the treatment or management of military combat or service-related orthopaedic injuries that significantly impact unit readiness and return-to-duty/work rates. Applicants are encouraged to address how the proposed research will support patient care closer to the point of injury and/or allow patients to more quickly return to duty/work. Clinical trials may be designed to evaluate promising new products, pharmacologic agents (drugs or biologics), devices, clinical guidance, and/or emerging approaches and technologies. Proposed projects may range from small proof-of-concept trials (e.g., pilot, first-in-human, phase 0) to demonstrate the feasibility or inform the design of more advanced trials, through large-scale trials to determine efficacy in relevant patient populations.The FY24 PRORP CTA differs from the FY24 PRORP Clinical Translational Research Award (CTRA) in that the CTRA allows for clinical research projects that may or may not include a clinical trial, whereas the CTA is restricted to clinical trials only.Funding from this award mechanism must support a clinical trial and may not be used for animal or preclinical studies. A clinical trial is defined in the Code of Federal Regulations, Title 45, Part 46.102 (45 CFR 46.102) as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include a placebo or another control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes.Studies that do not seek to measure safety, effectiveness, and/or efficacy outcome(s) of an intervention are not considered clinical trials.All applications submitted to this program announcement, regardless of the selected Focus Area, are eligible for Research Level 1.Collaborative Care Option (Research Level 2): Applications submitted to the FY24 PRORP CTA, with Focus Area Translation of Early Findings Soft Tissue Trauma, are eligible for a Collaborative Care Option (Research Level 2); refer to Section II.D.5, Funding Restrictions. The Collaborative Care Option provides additional support to encourage collaborative interdisciplinary research among physical therapists, occupational therapists, prosthetists, surgeons, and other orthopaedic care providers. The proposed research should include both surgical and rehabilitation strategies that create a cohesive project. Surgical strategies are reconstruction and repair and/or application of biologics, pharmaceuticals, and devices for the purpose of restoration of native architecture, composition, and function of traumatically injured tissues. Rehabilitative strategies are those that restore function following injury or illness, with the goal of optimal health and independence. Projects should integrate principles and approaches from surgical and rehabilitative strategies, beyond what each approach would provide by itself, with the goal of optimizing form, function, and independence for those who have sustained traumatic orthopaedic injuries. The rehabilitation strategy and the standard of care must be specified. Projects that follow patients across the continuum of care are highly encouraged. To encourage meaningful and productive multidisciplinary collaborations, projects submitted for this option must include at least one investigator with orthopaedic rehabilitation expertise and at least one clinician who specializes in orthopaedic or trauma care. A Letter of Collaboration is required from each specialist (i.e., rehabilitation expert and surgeon) who is serving as Key Personnel, excluding the Principal Investigator (PI), on the application. A clinician is defined as an individual who is credentialed (possesses the necessary degrees, licenses, and other certifications) and practicing as a care provider in a relevant capacity.If the proposed research includes a clinical trial of an investigational product to be conducted at international sites, an application to the relevant national Regulatory Agency of each host country must be submitted within 6 months of the award date.The government reserves the right to withdraw funding if an Investigational New Drug (IND) or Investigational Device Exemption (IDE) application and/or international regulatory application is necessary but has not been submitted within 6 months of the award date.For more information, a Human Subject Resource Document is provided at https://cdmrp.health.mil/pubs/pdf/Human%20Subjects%20Resource%20Document_DEC2022.pdf.Key aspects of the PRORP CTA mechanism: Clinical Trial Start Date: The proposed clinical trial is expected to begin no later than 6 months after the award date, or 12 months after the award date for studies regulated by the Regulatory Agency. Preliminary Data Are Required: Inclusion of preliminary data relevant to the proposed clinical trial is required. Study Population: The application should demonstrate the availability of and access to a suitable patient population that will support a meaningful outcome for the study. The application should include a discussion of how accrual goals will be achieved, as well as the strategy for inclusion of women and minorities in the clinical trial appropriate to the objectives of the study. Studies utilizing human biospecimens or datasets that cannot be linked to a specific individual, gender, ethnicity, or race (typically classified as exempt from Institutional Review Board [IRB] review) are exempt from this requirement. Intervention Availability: The application should demonstrate the documented availability of and access to the drug/compound, device, and/or other materials needed, as appropriate, for the proposed duration of the study. Personnel and Environment: The application should demonstrate the study teams expertise and experience in all aspects of conducting clinical trials, including appropriate statistical analysis, knowledge of U.S. Food and Drug Administration (FDA) processes (if applicable), and data management. The application should include a study coordinator(s) who will guide the clinical protocol through the local IRB of record and other federal agency regulatory approval processes, coordinate activities from all sites participating in the trial, and coordinate participant accrual. The application should show strong institutional support and, if applicable, a commitment to serve as the FDA regulatory sponsor, ensuring all sponsor responsibilities described in 21 CFR 312, Subpart D, are fulfilled. Statistical Analysis and Data Management Plans: The application should include a clearly articulated statistical analysis plan, a power analysis reflecting sample size projections that will answer the objectives of the study, and a data management plan that includes use of an appropriate database to safeguard and maintain the integrity of the data. If required by a Regulatory Agency, the trial must use a 21 CFR 11-compliant database and appropriate data standards.Womens Health Research: The CDMRP encourages research on health areas and conditions that affect women uniquely, disproportionately, or differently from men, including studies analyzing sex as a biological variable. Such research should relate anticipated project findings to improvements in women's health outcomes and/or advancing knowledge for women's health.Use of DOD or VA Resources: If the proposed research involves access to DOD or VA resources or databases, the application must describe the access at the time of submission and include a plan for maintaining access as needed throughout the proposed research. Refer to Section II.D.2.b.ii, Full Application Submission Components, for detailed information. Refer to the General Application Instructions, Appendix 1, for additional information.For the purposes of this funding opportunity, Regulatory Agency refers to the FDA or any relevant international Regulatory Agency unless otherwise noted.If the proposed clinical trial involves the use of a drug that has not been approved by the relevant Regulatory Agency for the country where the research will be conducted, then submission of an IND application, or equivalent, that meets all requirements under 21 CFR 312 may be required. It is the responsibility of the applicant to provide evidence from the IRB of record or the relevant Regulatory Agency if an IND, or equivalent, is not required. If an IND, or equivalent, is required, the regulatory application must be submitted to the relevant Regulatory Agency within 6 months of the CTA award start date. The IND, or equivalent, should be specific for the product and indication to be tested in the proposed clinical trial. For more information on IND applications specifically, the FDA has provided guidance at https://www.fda.gov/drugs/types-applications/investigational-new-drug-ind-application.If the investigational product is a device, then submission of an IDE, or equivalent, application that meets all requirements under 21 CFR 812 may be required. It is the responsibility of the applicant to provide evidence if an IDE, or equivalent, is not required. If an IDE, or equivalent, is required, the IDE application, or equivalent, must be submitted to the relevant Regulatory Agency within 6 months of the CTA award start date. The IDE, or equivalent, should be specific for the device and indication to be tested in the proposed clinical trial.The funding instrument for awards made under the program announcement will be grants (31 USC 6304).The anticipated total costs budgeted for the entire period of performance for an FY24 PRORP CTA should not exceed $2.5M (Research Level 1) or $3.25M (Research Level 2). Refer to Section II.D.5, Funding Restrictions, for detailed funding information.Awards supported with FY24 funds will be made no later than September 30, 2025.The CDMRP expects to allot approximately $13.25M to fund approximately four Research Level 1 and one Research Level 2 CTA applications. Funding of applications received is contingent upon the availability of federal funds for this program, the number of applications received, the quality and merit of the applications as evaluated by peer and programmatic review, and the requirements of the government. Funds to be obligated on any award resulting from this funding opportunity will be available for use for a limited time period based on the fiscal year of the funds. It is anticipated that awards made from this FY24 funding opportunity will be funded with FY24 funds, which will expire for use on September 30, 2030.