Grants for For profit organizations other than small businesses - Federal

The Department of States Bureau of Conflict and Stabilization Operations (CSO) aims to support a program to empower Pacific Island Countries (PICs) to identify areas of possible economic coercion or corruption and create strategies to prevent foreign influence from negatively impacting their ability to make sovereign decisions and to build their resilience to such influence. This program will provide regional expertise, background topical research and advice on coordinating a regional or national tabletop exercise or exercises (TTX) for the PICs.

This funding opportunity supports U.S.-based institutions in developing innovative quantum computing solutions to significantly improve computational chemistry and materials science for energy applications.

The PRMRP Investigator-Initiated Research Award (IIRA) supports fundamental research studies that will make an important contribution toward research, patient care, and/or quality of life for a disease or condition related to one of the FY24 PRMRP Topic Areas and one of the FY24 PRMRP Strategic Goals. This award mechanism is intended to support basic research that is exploratory in nature and seeks to further or validate preliminary findings for short- or long-term impact. Research projects may focus on any stage of basic laboratory research, ranging from fundamental research for the generation of knowledge, hypothesis, or models, to expansion of mature data.The rationale for a research idea may be derived from a laboratory discovery, population-based studies, a clinicians first-hand knowledge of patients, or anecdotal data. The project should include a well-formulated testable hypothesis based on existing evidence. Applications must include relevant preliminary data that support the rationale and feasibility for the proposed study. These data may be unpublished or from the published literature.This award mechanism is not intended to support translational research. Applicants seeking funding for projects that have progressed beyond the realm of basic research should consider one of the other FY24 PRMRP program announcements being offered. For information about these award mechanisms, see Section II.A.1, FY24 PRMRP Research Development Pipeline.

This grant provides funding to organizations for hosting a biennial conference focused on ethical, legal, and social implications research, promoting inclusivity and accessibility for diverse participants, including trainees and international researchers.

The "Promoting a Just Transition for All Workers" grant is currently being developed to support fair changes in the workforce, with updates and further details to be provided via the Grants.gov subscription service.

The key aspects of this award are: Overarching Question: FPA-RM applications must describe a unifying, overarching question that will be investigated by a set of research projects to address a critical unmet need relevant to rare melanoma research and/or patient care. The question may focus on one specific rare melanoma, or the question may be designed to address a critical unmet need that is relevant to multiple rare melanomas. Research Team: The overall effort will be led by a Principal Investigator (PI) with demonstrated success in leading large, focused projects. The PI is required to devote a minimum of 10% effort to this award. The PI will be the lead for one of the proposed research projects and is expected to create an environment that fosters and supports collaboration and innovation in a way that engages all members of the team. The research team assembled by the PI should be highly qualified and multidisciplinary, with an identified Project Leader(s) for the complementary and synergistic research project(s). The resources and expertise brought to the team by the Project Leader(s) should combine to create a robust collaboration. The PI and the Project Leader(s) do not have to be at the same organization. Research Projects: Applications should include multiple, distinct research projects that are each led by individual Project Leaders and address complementary aspects of the overarching question. Individual research projects may range from exploratory, hypothesis-developing studies through clinical trials. While individual projects should be capable of standing on their own high scientific merits, they should also be interrelated and synergistic to advance a solution beyond what would be possible through individual efforts. Each project, including hypothesis-developing studies, should propose a unique approach to addressing the overarching question and be capable of producing research findings with potential to advance the rare melanoma field and/or patient care. There should be a clear intent to progress toward translational/clinical work over the course of the effort. This award mechanism is not intended to support a series of research projects that are dependent on the success of the other project(s). All research projects must be based on a strong scientific rationale and preliminary data, as appropriate, that supports the feasibility of the proposed approach(es). Clinical trials are allowed; a research project proposing a clinical trial must include preliminary data. Implementation Plan: The research strategy to address the overarching question should be supported by an implementation plan that identifies critical milestones and outlines the knowledge, resources, and/or technical innovations that will be utilized to achieve the milestones. A plan for assessing individual project performance and progress toward addressing the overarching question should be included in the implementation plan. For multi-institutional collaborations, the application should discuss plans for communication and data transfer among the collaborating institutions, as well as how data, specimens, and/or products obtained during the study will be handled. Participating organizations should formalize an intellectual and material property plan. Milestone Meeting: The PI will be required to present an update on progress toward accomplishing the goals of the award at a Milestone Meeting to be held either virtually or in person in the National Capital Area after the conclusion of year 2 of the period of performance. The intent of the Milestone Meeting is to assess research progress, address problems, and define future directions. Research milestones to be accomplished by the end of year 2 must be clearly defined in the Statement of Work (SOW) and will be finalized during award negotiations. Up to two additional members of the research team may be invited to the meeting. If the research team includes rare melanoma consumer collaborators (see below), they should also be invited to attend the Milestone Meeting. The Milestone Meeting will be attended by members of the MRP Programmatic Panel, CDMRP staff, the USAMRAA Grants Officer, and other Department of Defense (DOD) stakeholders. Continued funding may be contingent upon the successful completion of specific research milestones and goals.

This funding opportunity supports innovative research and technology development in heliophysics, primarily for U.S. institutions, with provisions for foreign collaborators under specific guidelines.

With this solicitation, OJJDP seeks to develop and promote post-secondary and professional continuing education for child protection professionals in the field, including law enforcement officers, social workers, mental and medical health professionals, and prosecutors.

The U.S. Department of State, U.S. Embassy Malabo announces an Open Competition for organizations interested in submitting applications for projects that support greater and more effective protection of human rights and access to justice for the entire Equatoguinean population.All application submissions must be made electronically at Grants.gov and via email address: [email protected].

This funding opportunity supports researchers and organizations developing innovative prediction models for early detection of Alzheimer's Disease and related dementias, particularly focusing on data from underserved communities to address health disparities.

This funding opportunity provides $8 million to support U.S. organizations in developing innovative energy storage technologies that improve manufacturability and reduce production costs, with a focus on achieving commercialization and enhancing the energy storage industry.

This funding opportunity provides financial support to organizations working to prevent the spread of ISIS ideologies among Iraqi returnees from Northeast Syria, focusing on building local capacity for detection and intervention.

The Department of States Office to Monitor and Combat Trafficking in Persons (TIP Office) is pleased to invite organizations to submit proposals to provide global on-demand training and/or technical assistance in support of its global Training and Technical Assistance (T) Program. The Department of State’s Office to Monitor and Combat Trafficking in Persons (TIP Office) announces an open competition for projects in support of its global Training and Technical Assistance (T&TA) Program. The TIP Office manages foreign assistance programs dedicated to combating human trafficking outside of the United States. The TIP Office awards grants to combat all forms of human trafficking—sex trafficking, child sex trafficking, forced labor, domestic servitude, forced child labor, and the unlawful recruitment and use of child soldiers. The Department of State’s annual Trafficking in Persons Report (TIP Report) provides a diagnostic assessment of the efforts of governments to combat human trafficking and shapes our foreign assistance priorities. More information is available at: https://www.state.gov/international-programs-office-to-monitor-and-combattrafficking-in-persons/. The TIP Office’s Training and Technical Assistance (T&TA) program aims to increase government and/or civil society capacity to combat human trafficking. T&TA is most appropriate for addressing specific knowledge or other capacity gaps through targeted, short-term interventions. The TIP Office can provide training and/or technical assistance on topics spanning all 4Ps – Prevention, Protection, Prosecution, and Partnership. However, prevention is not often a direct or dominant focus for individual T&TA interventions, it is instead frequently integrated into the T&TA interventions through the lens of Protection, Prosecution, and/or Partnership. T&TA interventions are most often initiated by requests from U.S. Embassies abroad, or sometimes from our T&TA implementing partners. The TIP Office reviews requests for T&TA on a rolling basis throughout the year. Selected T&TA requests are then referred by the TIP Office to the relevant implementer, depending on the type of assistance requested, the implementer’s areas of expertise, and funding availability. The timeline to complete T&TA activities will depend on a variety of factors such as strategic priorities and country contexts. The selected implementer should be able to create an intervention concept note and budget in response to the specific T&TA request before the intervention is approved for implementation. The selected implementer should also expect to work closely with TIP Office staff throughout the development and implementation of interventions and activities. T&TA interventions can be standalone or they can lay the groundwork for or complement other programming, but they do not take the place of longer, multiyear programs. Individual T&TA interventions can sometimes also be structured in phases, with each phase being subject to TIP Office approval. T&TA activities may be conducted in countries across all regions of the world, so the scope of T&TA implementers’ capabilities must be global. The selected applicant should be able to respond to unanticipated requests for assistance in any country and/or region, with few exceptions. Some examples of what past T&TA interventions have looked like include, but are not limited to, the following: • Review of and edits to draft legislation or implementing regulations on a 24-hour turnaround; • Development and adoption of Foreign Government National Action Plan over the course of five months from receipt of request to final adoption; • Targeted technical assistance on the process to accede to United Nations Convention Against Transnational Organized Crime (UNTOC) and the Palermo Protocol; • Rapid diagnostic needs assessment on anti-trafficking capacity gaps of specialized anti-trafficking practitioners conducted within four weeks of initial request, followed by the development and delivery of a tailored training curriculum; • Tailored trainings delivered to law enforcement, prosecutors, and judges on how to build a human trafficking case in a country with limited resources and low capacity; • Tailored trainings delivered to shelter staff to improve identification, screening, and assistance of victims of trafficking, as well as technical assistance to develop necessary tools, such as screening forms and risk assessments; • Creation and implementation of a training series curriculum tailored to psychological and legal service providers to victims of trafficking in urban and rural locations both virtually and in-person, delivered over the course of several months; • Regional training for law enforcement and prosecutors, tailoring the materials for applicability across various participating countries in the region. While some T&TA activities can be conducted remotely, and the ability to provide some programming virtually is an asset to the T&TA Program and to the selected implementers, the majority of T&TA activities are conducted in-person. Because T&TA interventions can take place in settings where utilities, such as internet connectivity, are unreliable, the TIP Office will not be able to consider applications whose model of T&TA delivery is entirely remote.

This funding opportunity supports universities, research institutions, and non-profit organizations in conducting innovative research in measurement science to advance fundamental measurement methods and enhance our understanding of physics.

The Office of Naval Research (ONR) is interested in receiving a broad range of proposals for augmenting existing and/or developing innovative solutions that directly maintain, and/or cultivate a diverse, world-class Science, Technology, Engineering, and Mathematics (STEM) workforce to maintain the U.S. Navy and Marine Corps technological superiority. The goal of proposed efforts must provide solutions that establish, build, and/or maintain STEM educational pathways of U.S. citizens directly relevant to the needs of Department of Navys (DON) current and future workforce. As the capacity of the DON Science and Technology (S) workforce is interconnected with the STEM education system, DON recognizes the need to support efforts that can jointly improve STEM student outcomes and align educational and outreach efforts with Naval S current and future workforce needs. This announcement explicitly encourages programs that improve the capacity of education systems and communities to create impactful STEM educational experiences for students of all ages and the naval related workforce. Programs must aim to increase engagement in naval relevant STEM, and enhance the corresponding skills, knowledge, and abilities of participants. ONR encourages applicants to utilize current STEM educational research for informing program design and advancing STEM careers and opportunities of naval relevance.

The U.S. Department of State Bureau of Democracy, Human Rights, and Labor (DRL) announces an open competition for an evaluation project that contributes to building a portfolio of evidence regarding inclusive human rights in Ukraine. In support of this goal, DRL seeks to promote the use of sound data and generate findings on what works, for whom, and why in democracy and human rights programming abroad. Projects should support the following objective: the rights of marginalized, underserved, and at-risk individuals in Ukraine are recognized and respected within a democracy, rights, and good governance framework.

The National Institute of Diabetes and Digestive and Kidney Disorders (NIDDK) intends to promote a new initiative by publishing a Notice of Funding Opportunity (NOFO) to solicit applications for the TrialNet Coordinating Center (TNCC). The TrialNet network identifies people with type 1 diabetes (T1D) at stages before and after onset of clinical symptoms and enrolls them in trials and studies aimed at prevention of progression to clinical disease and preservation of insulin production. The TNCC participates in ongoing studies and intervention trials as well as the design and conduct of new studies and intervention trials. The TNCC will: (1) support a wide range of research projects in varying stages of development, implementation and completion, and (2) provide data and sample management, including standardized acquisition, quality control, dissemination and public accessibility. The TNCC will be responsible for network administration and operations, including the evaluation, selection, and funding (through subcontracts) of Clinical Centers and central support units (such as laboratories) necessary for the conduct of TrialNets clinical studies. The TNCC PD/PI will be a voting member of the TrialNet Executive and Steering Committees, contributing to network leadership. This NOFO requires a Plan for Enhancing Diverse Perspectives (PEDP), which will be assessed as part of the scientific and technical peer review evaluation. Applications that fail to include a PEDP will be considered incomplete and will be withdrawn. Applicants are strongly encouraged to read the NOFO instructions carefully and view the available PEDP guidance material. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The NOFO is expected to be published in Spring 2024 with an expected application due date in Summer 2024. This NOFO will utilize the U01 activity code. Details of the planned NOFO are provided below.

The FY24 RCRP RCDA supports the development of clinical or preclinical data sets and research resources that advance the field of rare cancers research and ultimately improve outcomes for individuals with rare cancers. Major gaps in patient care of rare cancers include lack of communication and dissemination strategies for rare cancers research and clinical findings within communities; lack of therapeutics and mechanistic studies to inform treatment development; lack of research and clinical resources, including patient tissues, cell, and tumor models; and lack of infrastructure for sharing data and other resources.The intent of this funding opportunity is to develop research platforms that can share resources and knowledge pertaining to available preclinical or clinical research models, molecular pathways, and therapeutic approaches to facilitate collaboration and information sharing among stakeholders such as researchers, patients, caregivers, clinicians, and other members of the rare cancers community.Clinical or preclinical datasets should strive to integrate or develop the following research resources. This list is not all-inclusive: Building and sharing rare tumor biospecimen repository with clinical annotation Databases/banks for centralizing and sharing data for patient registries that can be accessed globally Centralizing and sharing research models and molecular data related to genomics/ transcriptomics/immune profiling/proteomics/metabolomics/methylomics/bioinformatics Generating a data/reagent/model exchange program where researchers can list resources that they are willing to share and are tagged with indications that may be relevant Platform to enable or leverage longitudinal studies of disease natural history and treatment response Development of novel methods and systems for collection, sharing, and analysis of data or biospecimensApplicants should include a well-formulated project design based on a strong scientific rationale and clearly articulate how the proposed resource platform or community development addresses an unmet need in rare cancers research. Applicants should explain the advantage of their approach to developing resources or community versus standard methodologies, techniques, or scopes. A clear plan for collaboration and data sharing needs to be demonstrated. It is critical to demonstrate how the outcome of the proposed project can benefit type(s) or sub-type(s) of rare cancers. It is encouraged for the research platform/resource to have an effect on multiple types or sub-types of rare cancers.Key Elements of the Resource and Community Development Award are as follows: Impact: Outcomes of the RCDA must have potential for major impact on an unmet need in rare cancers research. A resource, as developed in the proposed research, should aim forDOD FY24 Rare Cancers Resource and Community Development Award 5long-term anticipated advantages toward greatly improving outcomes for people with rare cancers. Patient Advocate Partnership: Applications to the RCDA funding opportunity are required to include patient advocates who are involved with patient advocacy organization(s). The research team must include at least two rare cancers patient advocates who will be early and integral partners throughout the planning and implementation of the research project. Patient advocates should be involved in the development of the research question, project design, oversight, and evaluation, as well as other significant aspects of the proposed project. Interactions with other team members should be well integrated and ongoing, and not limited to attending seminars and semi-annual meetings. The patient advocates must be individuals who have been directly impacted by a rare cancer either by being diagnosed themselves or as a caretaker/family member of a patient, and they should be active in a cancer advocacy organization or within a support group focused on their rare cancer. Their role should be focused on providing objective input on the research and its potential impact for individuals with or at risk for a rare cancer. The patient advocates should have a high level of understanding of current rare cancers research. Preliminary Data: Due to the developmental nature of this award, preliminary data are not required but may be included, if available, to address the feasibility of the resource to be developed. Whether or not preliminary data are included, applications must apply solid scientific rationale and logical reasoning based on existing knowledge to the development of the proposed product. Clinical Research: Research involving human subject use is permitted under this mechanism but is restricted to studies without clinical trials. Clinical trials will not be supported. Applications focused on clinical research should demonstrate how the study will leverage clinical information to address knowledge gaps in the development of platforms that can be utilized for sharing data and tissue, the development of clinical annotation datasets, process development, and/or infrastructure development. Applied Research: Preclinical studies utilizing or creating animal models to further research into rare cancers may be supported by this funding opportunity. The RCDA is intended to support projects that will have the potential to move beyond the realm of basic research, with results that may impact clinical research or patient outcomes. Community Building: A plan describing how the rare cancers stakeholder community will be built/enhanced and the communitys involvement with developing the resource platform is required. It is also important to justify how the community is essential for the development and sustainment of the resource platform. Dissemination: A Dissemination Plan is required. The plan should describe the means by which the fully developed resource platform will be made easily available to the scientific and/or clinical community. Dissemination of resource platform will play a major role by not only educating the rare cancer community about the recent progress, but also help to develop an informational network.DOD FY24 Rare Cancers Resource and Community Development Award 6 Sustainment: A plan that outlines the sustainability of the resource in the future is required. The plan should detail the types of rare cancers that are less studied in the collaborations and the resources to be gathered, annotated, and sustained. Additional expansion and feasibility plans should be included. It is important to demonstrate how the outcomes of the current award will be continued and eventually will help the rare care cancer community, beyond the award period.A congressionally mandated Metastatic Cancer Task Force was formed with the purpose of identifying ways to help accelerate clinical and translational research aimed at extending the lives of advanced state and recurrent patients. As a member of the Metastatic Cancer Task Force, CDMRP encourages applicants to review the recommendations (https://health.mil/Reference-Center/Congressional-Testimonies/2018/05/03/Metastatic-Cancer-Research) and submit research ideas to address these recommendations provided they are within the limitations of this funding opportunity and fit within the FY24 RCRP priorities.Collaborations between researchers at military or Veteran institutions and non-military institutions are strongly encouraged. These relationships can leverage knowledge, infrastructure, and access to unique clinical populations that the partners bring to the research effort, ultimately advancing cancer research that is of significance to the Warfighter, military Families, and the American public.Innovative research involving nuclear medicine and related techniques to support early diagnosis, more effective treatment, and improved health outcomes of active-duty Service Members and their Families is encouraged. Such research could improve diagnostic and targeted treatment capabilities through noninvasive techniques and may drive the development of precision imaging and advanced targeted therapies.CDMRP encourages research on health areas and conditions that affect women uniquely, disproportionately, or differently from men, including studies analyzing sex as a biological variable. Such research should relate anticipated project findings to improvements in womens health outcomes and/or advancing knowledge for women's health.All projects should adhere to a core set of standards for rigorous study design and reporting to maximize the reproducibility and translational potential of clinical and preclinical research. The standards are described in SC Landis et al., 2012, A call for transparent reporting to optimize the predictive value of preclinical research, Nature 490:187-191 (https://www.nature.com/nature/journal/v490/n7419/full/nature11556.html). While these standards are written for preclinical studies, the basic principles of randomization, blinding, sample-size estimation, and data handling derive from well-established best practices in clinical studies.

With this solicitation, BJS seeks to administer the Bureau of Justice Statistics Statistical Support Program (BJS-SSP). The primary aim of the BJS-SSP is to provide statistical and methodological support for existing and new data collections. BJS collects, analyzes, publishes, and disseminates information on policing, prosecution, courts, institutional corrections, community supervision, and victimization. The BJS-SSP will support efforts to expand the agencys capacity to collect, analyze, and report criminal justice data, increasing the breadth of substantive issues.

This funding opportunity provides financial support for U.S. universities and research organizations to collaborate on developing sustainable semiconductor materials and processes using artificial intelligence, with a focus on enhancing industry practices and workforce skills.