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Grants for Nonprofits - Federal

Explore 5,500 grant opportunities

Native Public Health Resilience Planning
$200,000
HHS-IHS (Indian Health Service)
Federal

Application Deadline

May 14, 2024

Date Added

Mar 28, 2024

The purpose of this program is to assist applicants to establish goals and performance measures, assess their current management capacity, and determine if developing a Public Health program is practicable. Specifically, programs should assess the availability and feasibility of the 10 Essential Public Health Services (EPHS), described further below. As part of the IHS mission to raise the physical, mental, social, and spiritual health of American Indians and Alaska Natives to the highest level, this program seeks to build on and strengthen community resilience by supporting wider access to the 10 EPHS in Indian Country, a framework designed to offer all people a fair and just opportunity to achieve optimal health and well-being. For more information on the EPHS, please visit https://www.cdc.gov/publichealthgateway/publichealthservices/essentialhealthservices.html. The framework of the EPHS has served as a guide to the public health field since 1994, and describes the public health activities that all communities should undertake, including, 1) monitor health status to identify and solve community health problems, and 2) Diagnose and investigate health problems and health hazards in the community. The EPHS framework was revised in 2020 with an emphasis on equity and reflects current and future public health practice goals. The EPHS have been included in the HHS Healthy People initiatives since 2010, when the initiative first included a focus area of Public Health Infrastructure with the goal to ensure that Federal, Tribal, state, and local health agencies have the infrastructure to provide essential public health services effectively.

Health
Native American tribal organizations
DoD Breast Cancer, Breakthrough Award Levels 1 and 2
$3,350,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Sep 10, 2025

Date Added

Jun 17, 2025

This funding opportunity provides financial support for innovative breast cancer research projects aimed at preventing the disease, understanding its recurrence, or improving treatment, targeting both early-stage and more developed studies from a range of eligible organizations and researchers.

Health
Public and State controlled institutions of higher education
Reducing Recidivism for Female Juvenile Delinquents
$525,000
U.S. Department of Justice (Office of Juvenile Justice Delinquency Prevention )
Federal

Application Deadline

Oct 27, 2025

Date Added

Sep 18, 2025

This funding opportunity provides financial support to organizations developing or expanding programs that help reduce reoffending among female juvenile delinquents by addressing their unique needs through direct intervention services.

Law Justice and Legal Services
State governments
Bluff Wetland 60% Design
$300,000
U.S. Department of the Interior (Bureau of Reclamation)
Federal

Application Deadline

Oct 17, 2025

Date Added

Aug 14, 2025

This funding opportunity provides financial support to non-federal organizations for advancing the design of a wetland project aimed at improving habitat for endangered fish species in the San Juan River Basin.

Environment
State governments
Fundamental Research to Counter Weapons of Mass Destruction
$500,000,000
U.S. Department of Defense - Defense Threat Reduction Agency
Federal

Application Deadline

Sep 30, 2024

Date Added

Feb 22, 2022

**AMENDED on DECEMBER 11 2023**: The latest revision is posted as Amendment 18. Potential applicants are strongly encouraged to review the Amendment in its entirety, as it updates several sections. Specifically, ATTACHMENT 1: SPECIFIC TOPICS now includes Basic Research Topics N1-N4, with white papers due by 11:59pm EST on 5 February 2024. White papers may not be considered if they are received after this deadline. In addition, submissions to the general thrust areas in accordance with the requirements detailed in the BAA are also welcome. ** Please note that all correspondence must be sent to the appropriate Agency contact identified in Section 7. Agency Contacts. **

Science and Technology
Public and State controlled institutions of higher education
Ukraine Mental Health Initiative for National Development Activity
$50,000,000
Agency for International Development (Ukraine USAID-Kiev)
Federal

Application Deadline

Jan 15, 2025

Date Added

Nov 26, 2024

This grant provides up to $50 million over five years to non-governmental organizations working to develop a comprehensive mental health care system in Ukraine, focusing on improving access, quality, and workforce capacity while promoting resilience and social inclusion.

Health
Nonprofits
DoD Toxic Exposures Clinical Trial Partnership Award
$4,200,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Oct 16, 2025

Date Added

Jun 6, 2025

This grant provides funding for collaborative clinical trials aimed at improving the diagnosis and treatment of health issues related to military toxic exposures, targeting researchers and institutions involved in this critical area of study.

Science and Technology
For profit organizations other than small businesses
Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Organizational Research Education Award to Promote Diversity (UE5 - Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 21, 2025

Date Added

Feb 12, 2025

This funding opportunity supports organizations in developing career development and mentoring programs for early-career researchers from diverse backgrounds who are underrepresented in the biomedical and behavioral sciences.

Education
State governments
Ex Vivo Models for Studies at the Intersection of HIV and Addictive Substance Use (R01 Clinical Trial Not Allowed)
$2,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 13, 2025

Date Added

Dec 31, 2024

This funding opportunity supports research using human-derived ex vivo models to explore how HIV interacts with addictive substances, focusing on their effects on the brain and immune system.

Education
State governments
Targeting Inflammasomes in HIV and Substance Use (R01 Clinical Trial Not Allowed)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 13, 2025

Date Added

Oct 30, 2024

This funding opportunity supports research on how inflammasome activation affects neurocognitive disorders and immune function in individuals with HIV and substance use disorders, encouraging studies that explore the interactions between these factors.

Education
State governments
OVW Fiscal Year 2025 Grants to Engage Men and Youth in Preventing Domestic Violence, Dating Violence, Sexual Assault, and Stalking Program
$350,000
U.S. Department of Justice (Office on Violence Against Women)
Federal

Application Deadline

Jul 8, 2025

Date Added

May 28, 2025

This grant provides funding to community organizations and local governments to engage men and youth in initiatives that prevent domestic violence, dating violence, sexual assault, and stalking.

Law Justice and Legal Services
County governments
Scalable, Adaptive, and Resilient Autonomy (SARA)
$2,500,000
DOD-AMC (Dept of the Army -- Materiel Command)
Federal

Application Deadline

May 10, 2024

Date Added

Apr 11, 2024

**CYCLE 4 POSTED ON 10 APRIL 2024. SEE ATTACHED UPDATED ANNOUNCEMENT FOR SPECIFIC TOPICS OF INTEREST IN CYCLE 4 AND SUBMISSION INFORMATION** **CYCLE 3, ORIGINALLY POSTED ON 21 MARCH 2023, IS UPDATED TO INCLUDE A QUESTION AND ANSWER DOCUMENT AND TO UPDATE THE SUBMISSION DATE TO 5 MAY 2023 BY 1700 EASTERN TIME** **CYCLE 3 POSTED ON 21 MARCH 2023. SEE ATTACHED UPDATED ANNOUNCEMENT FOR SPECIFIC TOPICS OF INTEREST IN CYCLE 3 AND SUBMISSION INFORMATION** **CYCLE 2 POSTED ON 8 FEBRUARY 2021. SEE ATTACHED UPDATED ANNOUNCEMENT FOR SPECIFIC TOPICS OF INTEREST IN CYCLE 2 AND SUBMISSION INFORMATION** Purpose: Future Army forces will need to conduct cross-domain maneuver (CDM) and at times, operate semi-independently, disbursed, and while communications and infrastructure such as Global Positioning System (GPS) are disrupted or denied. Robotics and Autonomous Systems (RAS) will play a key role in expanding the operational reach, situational awareness, and effectiveness of maneuver forces in CDM. The Combat Capabilities Development Command (CCDC) Army Research Laboratory (ARL) is focused on developing fundamental understanding and informing the art-of-the-possible for warfighter concepts through research to greatly improve air and ground based autonomous vehicle perception, learning, reasoning, communication, navigation, and physical capabilities to augment and increase the freedom of maneuver in complex and contested environments. The Scalable, Adaptive, and Resilient Autonomy (SARA) program is focused on developing and experimentally accelerating emerging research in autonomous mobility and maneuverability, scalable heterogeneous and collaborative behaviors, and human agent teaming to realize adaptive and resilient Intelligent Systems that can reason about the environment, work in distributed and collaborative heterogeneous teams, and make op-tempo decisions to enable Autonomous Maneuver in complex and contested environments. In order to achieve this vision, advancements are needed in following: Novel methods for all-terrain ground and aerial maneuver to interact with and move through complex environments. Methods for scalable and heterogeneous collaborative behaviors in support of collaborative air and ground manned-unmanned teaming operations. Techniques for improved perception, decision-making, and adaptive behaviors for fully autonomous maneuver in contested environments. Methods, metrics, and tools to facilitate, simulate, and enable testing and evaluation of emerging approaches for intelligent and autonomous systems under Army relevant constraints and environments Experimental testbeds to develop and refine knowledge products to inform and transition technology to Army stakeholders.

Science and Technology
Nonprofits
Engineering Next-Generation Human Nervous System Microphysiological Systems (R01 Clinical Trials Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 7, 2024

This funding opportunity supports researchers in developing advanced human cell-based models of the nervous system to better understand its development, function, and aging, particularly in relation to neurological and age-related diseases.

Health
State governments
International Capacity Development for Weather and Climate Observations and Forecasting and Disaster Risk Reduction
$75,000,000
U.S. Department of Commerce (DOC NOAA - ERA Production)
Federal

Application Deadline

Nov 29, 2024

Date Added

Oct 3, 2024

This funding opportunity provides financial support to U.S.-based non-profit organizations and academic institutions to help improve weather and climate forecasting capabilities in developing countries, ultimately enhancing their disaster risk reduction efforts.

Environment
Nonprofits
Pilot Studies for the Spectrum of Alzheimers Disease/Alzheimers Disease-Related Dementias and Age-Related Cognitive Decline (R61 Clinical Trial Optional)
$325,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 18, 2024

Date Added

Dec 23, 2022

This funding opportunity provides financial support for research projects that explore new treatments and interventions for Alzheimer’s Disease, related dementias, and age-related cognitive decline, encouraging innovative approaches and pilot studies to improve future clinical trials.

Health
State governments
Celebrating Americas 250th Anniversary
$250,000
U.S. Department of State (U.S. Mission to Lebanon)
Federal

Application Deadline

Sep 2, 2025

Date Added

Aug 3, 2025

This funding opportunity provides financial support for Lebanese not-for-profit organizations, private educational institutions, and individuals to create programs that celebrate the 250th anniversary of the Declaration of Independence while fostering U.S.-Lebanese cultural exchange and partnership.

International Development
Individuals
Notice of Intent to Publish a Funding Opportunity Announcement for Center of Excellence for Systems Modeling of Infection and Immunity across Biological Scales (U54 Clinical Trial Not Allowed)
$5,000,000
HHS-NIH11 (National Institutes of Health)
Federal

Application Deadline

Jun 5, 2024

Date Added

Nov 24, 2023

TheNational Institute of Allergy and Infectious Diseases (NIAID),intendstopublish a Notice of Funding Opportunity (NOFO) tosolicit applications for a Center of Excellence (CoE) for Systems Modeling of Infection and Immunity across Biological Scales that will: Develop and conduct innovative computational multi-scale modeling research for NIAID priority biomedical questions, including HIV/AIDS; Coordinate the NIAID and broader modeling community that conducts research on infectious- and immune-mediated diseases, through model and data sharing, opportunity funds, educational activities, and community-organizing activities; Conduct innovative research and coordination activities to improve data and model sharing in the NIAID and broader modeling community; Foster a diverse community of new and existing investigators dedicated to Infectious and Immune-mediated Disease (IID) multi-scale modelingand collaboration between experimental and computational scientists; Serve as point of contact to NIAID for the modeling community and pivot research activities to address acutely emerging NIAID needs, such as outbreaks, epidemics, or pandemics; Establish community development and educational opportunities in IID multi-scale modeling for students, post-doctoral fellows, and new/early-stage investigators; Enable new approaches for multi-scale model sharing and reproducibility aligned with theFAIR (Findable, Accessible, Interoperable, and Reusable) principles and theNIAID Data Ecosystem Portal. This Notice isbeing provided toallow potential applicants sufficient timetodevelop meaningful collaborations andprojects. Potentialapplicantsareencouraged tousethistimetodevelop leadership teams to cover the full range of expertise and experience to develop the coordinating cores and research projects that will represent and enable strong scientific and operational connections between the CoE and the larger IID modeling community. This NOFO will utilize theU54 activity code.Details for a pre-application webinar will be provided in the published NOFO.

Health
State governments
U.S. Mission Vietnam PDS NOFO
$30,000
U.S. Department of State (U.S. Mission to Vietnam)
Federal

Application Deadline

Mar 2, 2025

Date Added

Dec 31, 2024

This grant provides funding for non-profits, educational institutions, and government organizations to implement programs that promote understanding of emerging technologies, enhance English teacher training, strengthen U.S. alumni networks, and celebrate 30 years of U.S.-Vietnam relations.

Education
Nonprofits
Preventing U.S. Adversaries Access to Critical Technologies and Exploitation of Scientific and Commercial Facilities for Military Advancement
$1,000,000
U.S. Department of State (Bureau of International Security-Nonproliferation)
Federal

Application Deadline

Jul 30, 2025

Date Added

Jun 2, 2025

This funding opportunity provides financial support to various organizations and institutions to help prevent adversaries from exploiting advanced technologies and commercial facilities for military purposes, focusing on enhancing global partnerships and security measures.

International Development
For profit organizations other than small businesses
Urban and Community Forestry Planning Grant Program
$65,000
U.S. Forest Service
Federal

Application Deadline

Jan 31, 2025

Date Added

Nov 1, 2024

This program provides funding to Connecticut local governments and non-profits to improve urban forests, focusing on preserving trees and expanding tree canopy in underserved communities.

Environment
Nonprofits