Grants for Nonprofits - Federal

This funding opportunity provides financial support to organizations that assist healthcare providers in expanding telehealth services, particularly in rural and underserved areas across the United States.

This program provides funding for collaborative projects that combine artificial intelligence and geoscience research to tackle important Earth system challenges.

This funding opportunity supports innovative cancer research projects that explore new treatments, diagnostics, and strategies to reduce disparities in cancer care, targeting a wide range of researchers and institutions.

This funding opportunity provides $6 million to the University of South Florida to continue managing the TEDDY study's Data Coordinating Center, which investigates the environmental causes of type 1 diabetes in children.

This grant provides funding to organizations and individuals in Suriname to empower women entrepreneurs through education, mentorship, and community building, fostering sustainable business growth.

This funding opportunity supports researchers in validating new therapeutic targets for Alzheimer's Disease-Related Dementias by developing innovative technologies and collaborative approaches to improve treatment strategies.

This grant provides funding for U.S. educational and research institutions to collaborate with Ukrainian partners on projects that enhance security, stability, and innovation in areas such as cybersecurity, defense technology, and agriculture.

This grant provides financial support and mentorship for early-stage clinical scientists dedicated to cancer research, enabling them to conduct independent clinical trials and develop their research careers.

This program provides funding for researchers and educators in STEM fields to explore and promote ethical practices in research, particularly focusing on diversity, equity, and responsible conduct.

This program provides funding to U.S.-based nonprofit publishers and accredited higher education institutions to create free digital editions of books based on research supported by the National Endowment for the Humanities.

YSEALI (yseali.state.gov) is the U.S. governments signature initiative to engage emerging leaders in Southeast Asia. The program aims to create a network of young Southeast Asian leaders who work across national borders to solve common problems. Through a variety of programs and engagements, YSEALI seeks to build the leadership capabilities of youth in the region, strengthen ties between the United States and Southeast Asia, and nurture a community of leaders who work across borders to solve shared issues. YSEALI is open to young leaders ages 18-35 who are both citizens and residents of the Association of Southeast Asian Nations (ASEAN) member countries (Brunei, Burma, Cambodia, Indonesia, Laos, Malaysia, the Philippines, Singapore, Thailand, and Vietnam) or Timor-Leste. Responding to priorities from youth in the ASEAN region, YSEALI programs focus on four themes (Civic Engagement, Economic Empowerment and Social Entrepreneurship, Education and Environmental Issues). One component of YSEALI is the annual Regional Workshops held across Southeast Asia on strategic topics. Focusing on youth and community action, the YSEALI Blue Economy Regional Workshop aims to advance the YSEALI theme of Sustainable Development and U.S. Embassy Jakartas strategic goals by examining how technology and regional collaboration can create sustainable economic growth in sectors related to ocean ecosystems. These include the emerging sectors of renewable blue energy, desalination, and blue carbon, as well as traditional sectors of fisheries, marine conservation, and marine transportation. It also supports U.S. Embassy Singapores strategic goals by bringing Singapore, limited in space and natural resources, into regional partnership roles on blue economic issues, from green shipping and renewable energy to desalination and ocean-based food security. The workshop should be a minimum of five and maximum of six days - inclusive of travel days (with international travel into and out of Singapores Changi airport). Lodging and conference venue should be in Batam with the majority of workshop sessions taking place in Batam, but day trips to Singapore and other areas around Batam to explore sustainable fishing, blue energy, or green port initiatives like the U.S-Singapore green shipping corridor can be included. The program may also include meetings and activities in Singapore on arrival or prior to departure. Travel to and from Batam should be via high-speed ferry services. This workshop will bring together 60 YSEALI members from ASEAN countries and Timor Leste who have an interest in emerging energy technologies, coastal economic development, environmental development, environmental science, green technology, marine conservation, social equity, economic vitality, and the ability to lead. Proposals may also include participation of the Young Pacific Leaders (YPL) network to create synergy between communities working on blue issues economy across Southeast Asia and the Pacific. YSEALI leaders will have the opportunity to share new ideas and perspectives on how to harness the potential of the blue economy to increase economic growth in a sustainable and science-based way. The workshop should include sessions on defining blue economy, introducing ASEAN and ASEAN member state initiatives related to blue economy, regional collaboration, and multi-nation funding opportunities. The workshop should look at blue economy issues in a globalized society and examine approaches taken by the United States and countries in the region. The concepts of leadership, giving back, and strengthening a Southeast Asian/ASEAN identity based on shared values and shared challenges should be integrated into the program. Workshop speakers/facilitators/mentors should be citizens of the United States, an ASEAN member country, or Timor-Leste. The workshop should include site visits to companies, government-affiliated programs, or non-governmental organizations where innovative approaches are being taken to harness blue economy potential. The proposal should include workshop follow-on activities such as virtual collaborative work, projects funded through small seed grants, and/or ongoing mentorship. The follow-on activity should be included in the monitoring and evaluation plan. The workshop should also include a cultural or community service component that promotes ASEAN unity, and the United States as a partner to ASEAN. The recipient is expected to develop syllabus materials and an event program with participant and speaker biographies, as well as design banners, backdrops, and other printed materials. The recipient is expected to design a digital engagement strategy for workshop participants and social media audiences, including live video or live online engagement during the program. The proposal should include workshop follow-on activities such as virtual collaborative work, projects funded through small seed grants, or ongoing mentorship. The follow-on activity should be included in the monitoring and evaluation plan. The proposal should include a pre and post workshop survey to measure the overall effectiveness of the workshop as well as any changes to the participants knowledge of the workshop topic. No new website specific to the event should be created or launched. Domain, hosting and build costs will not be covered.

This grant provides funding to support the development of comprehensive strategies for creating next-generation HIV treatments and prevention methods, helping researchers prepare for FDA approval processes.

This funding opportunity supports state, tribal, and local agencies, along with research institutions, in evaluating consumer education strategies to help parents make informed choices about early child care and education.

The FY24 BCRP Clinical Research Extension Award aims to extend or expand the data collection, follow-up, and analysis of breast cancer clinical studies. The intent of this mechanism is to increase the clinically relevant impact of breast cancer patient participation in clinical research by addressing the knowledge lost due to early trial termination, limited patient follow-up, or suboptimal sample and/or data collection and analysis. Patients contributions of tissue, serum, and other biologic specimens and their data are invaluable to saving lives. The BCRP has created this mechanism to help ensure that science values those contributions with research that maximizes their impact.The critical components of this award mechanism are:Impact: Research supported by the FY24 BCRP Clinical Research Extension Award will have the potential to extend or affect the impact of the previously funded clinical trial or study or will result in new impact and accelerate progress toward ending breast cancer.Research Scope: Although not all-inclusive, research proposed under the FY24 BCRP Clinical Research Extension Award may entail a deeper molecular analysis of clinical samples, initiation of new correlative studies, biomarker validation, or continuing clinical follow-up of patients enrolled in an open/ongoing or completed clinical trial. The proposed research may be hypothesis-testing or -generating or may be designed to generate clinically annotated and molecularly characterized experimental platforms, including patient-derived models or tissue arrays. Innovation is not a criterion for this award mechanism. Projects proposing to conduct clinical trials will not be supported.Feasibility: Preliminary data to support the scientific rationale and feasibility of the research approaches are required. The applicant must demonstrate availability of, and accessibility to, the necessary resources or populations to accomplish the proposed research.Data Evaluation and Sharing: Proposed research should be based on a study sample size that will ensure that the results support valid conclusions or will generate a meaningful hypothesis. It is the applicants responsibility to provide sufficient evidence that the sample size is appropriate to meet the studys objectives and outline the statistical methods and considerations they will employ in their data analysis. The applicant must outline a data-sharing plan for the scientific community to have access to the experimental platforms and molecular and other data generated from the proposed research.applications that include meaningful and productive partnerships between investigators. The Partnering PI Option is structured to accommodate two Principal Investigators (PIs). One PI will be identified as the Initiating PI, who will be responsible for the majority of the administrative tasks associated with application submission. The other PI will be identified as a Partnering PI. The PIs may have expertise in similar or disparate scientific disciplines, but each PI is expected to bring a distinct contribution to the application. Both PIs should contribute significantly to the development of the proposed research project, including the Project Narrative, Statement of Work (SOW), and other required components. The application should clearly demonstrate that both PIs have equal intellectual input into the design of the project and will devote similar and appropriate levels of effort to the conduct of the project. It is expected that funding will be balanced between both PIs unless appropriately justified. The application is expected to describe how the PIs unique expertise combined as a partnership will better address the research question, how the unique expertise that each individual brings to the application is critical for the research strategy and completion of the SOW, and why the work should be done together rather than through separate efforts. Applicants are discouraged from being named as a PI, Initiating PI, or Partnering PI on multiple Clinical Research Extension Award applications unless they are clearly addressing distinct research questions. If recommended for funding, each PI will be named on separate awards to the recipient organization(s). Each award will be subject to separate reporting, regulatory, and administrative requirements. For individual submission requirements for the Initiating and Partnering PIs, refer to Section II.D.2, Content and Form of the Application Submission.Personnel: Applications are expected to include an appropriate and robust research team with the combined backgrounds and breast cancer-related expertise to enable successful conduct of the project.Consumer Advocates: Applications are required to include consumer advocate involvement. The research team must include two or more breast cancer consumer advocates, and it is the applicants responsibility to outline the advocates role in the design and execution of the study. As lay representatives, the consumer advocates must be individuals who have been diagnosed with breast cancer and are actively involved in a breast cancer advocacy organization. Their role should be independent of their employment, and they may not be employees of any organizations participating in the application. The consumer advocates should have a high level of knowledge of current breast cancer issues and the appropriate background and/or training in breast cancer research to contribute to the project. Their role should be focused on providing objective input throughout the research effort and its potential impact for individuals with, or at risk for, breast cancer.A congressionally mandated Metastatic Cancer Task Force was formed with the purpose of identifying ways to help accelerate clinical and translational research aimed at extending the lives of advanced state and recurrent patients. As a member of the Metastatic Cancer Task Force, CDMRP encourages applicants to review the recommendations (https://health.mil/Reference-Center/Congressional-Testimonies/2018/05/03/Metastatic-Cancer-Research) and submit research ideas to address these recommendations provided they are within the limitations of this funding opportunity and fit within the FY24 BCRP priorities.Innovative research involving nuclear medicine and related techniques to support early diagnosis, more effective treatment, and improved health outcomes of active-duty Service Members and their Families is encouraged. Such research could improve diagnostic and targeted treatment capabilities through noninvasive techniques and may drive the development of precision imaging and advanced targeted therapies.The proposed research must be relevant to active-duty Service Members, Veterans, military beneficiaries, and/or the American public. Collaborations between researchers at military or Veteran institutions and non-military institutions are strongly encouraged. These relationships can leverage knowledge, infrastructure, and access to unique clinical populations that the partners bring to the research effort, ultimately advancing cancer research that is of significance to the Warfighter, military Families, and the American public.Clinical research encompasses research with human data, human specimens, and/or interaction with human subjects that may or may not be considered a clinical trial. For this funding opportunity, research involving human subjects, human specimens, and data, including extended or expanded clinical follow-up of patients, is permitted; however, this award cannot be used to conduct clinical trials.A clinical trial is defined in the Code of Federal Regulations, Title 45, Part 46.102 (45 CFR 46.102) as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include a placebo or another control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes.Studies that do not seek to measure safety, effectiveness, and/or efficacy outcome(s) of an intervention are not considered clinical trials.The funding instrument for awards made under the program announcement will be grants (31 USC 6304).The anticipated direct costs budgeted for the entire period of performance for an FY24 BCRP Clinical Research Extension Award should not exceed $5M for applications with a single PI or $6M if applying under the Partnering PI Option. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.Awards supported with FY24 funds will be made no later than September 30, 2025.The CDMRP expects to allot approximately $18.6M to fund approximately two Clinical Research Extension Award applications. Funding of applications received is contingent upon the availability of federal funds for this program, the number of applications received, the quality and merit of the applications as evaluated by peer and programmatic review, and the requirements of the government. Funds to be obligated on any award resulting from this funding opportunity will be available for use for a limited time period based on the fiscal year of the funds. It is anticipated that awards made from this FY24 funding opportunity will be funded with FY24 funds, which will expire for use on September 30, 2030.

This funding opportunity provides financial support to various organizations for implementing evidence-based programs that help older adults and individuals with disabilities reduce the risk of falls through education and outreach.

This funding opportunity provides financial support to organizations that empower young leaders in Southeast Asia to tackle climate change and environmental challenges through leadership training, collaboration, and capacity-building initiatives.

**A modification to this NOFO was made on April 4, 2024. There are no content changes to application or program requirements. The funding opportunity number was changed from HHS-2024-ACF-ACYF-CW-0056 to HHS-2024-ACF-ACYF-CT-0056. There were changes made in Section I, Statutory Authority; and Section II, Expected Number of Awards and Estimated Total Funding. In Section III, Eligibility was changed to exclude for-profit organizations and small businesses. American Indian and Alaska Native (AI/AN) children are nearly 3 times more likely to enter foster care, compared to non-Native children. These four year grants are intended to generate evidence for how best to effectively implement child welfare practices and ongoing active efforts to maintain AI/AN families by funding state and tribal partnerships to jointly design and operate Indian child welfare best practice implementation demonstration sites. The evidence generated and lessons learned through this effort are intended to contribute to implementation efforts nationally to help maintain and preserve AI/AN families and allow their children to remain connected to their communities and cultures. The purpose of this notice of funding opportunity is to create and implement intergovernmental partnership models to improve implementation of child welfare best practices that are culturally appropriate for federally recognized AI/AN children to prevent maltreatment, removal from families and communities, and improve safety, permanency, and well-being. Recipients will serve as demonstration sites to design and implement projects to effectively implement culturally appropriate best practices in Indian child welfare, including measuring improvements in child welfare practice, Indian child welfare codes, legal and judicial processes, case monitoring, case planning, data collection, in-home family preservation services, infrastructure, and systems change. Partnerships must include the state Court Improvement Program, the state child welfare agency, and one or more tribal governments or tribal consortia including corresponding tribal court(s). The "Tribal government" partner(s) may be tribal child welfare agencies where appropriate under tribal law or custom.Effective culturally appropriate best practices for implementation require a high degree of collaboration between state and tribal courts and Indian child welfare agencies. Thus, both states and tribes must identify, build, and enhance necessary capacities. State/tribal collaborations will work together to craft solutions for longstanding challenges to providing effective best practices in Indian child welfare in ways that work best for their communities. This funding opportunity is intended to encourage state and tribal governments to work together to find creative, rational ways to meet the needs of AI/AN families with culturally appropriate best practices in Indian child welfare, with active efforts to retain or reunite Indian children with family as the gold standard for best Indian child welfare practice. The award also provides an important opportunity for states and tribes to build or strengthen relationships of trust by working together toward common family preservation goals. As part of the project, recipients may also consider the role of civil legal services in implementation efforts. Assessment of the success and/or need for legal representation to parties in Indian child welfare cases may be included in project work, as may provision of direct civil legal services, to the extent that such legal services are an identified part of a pilot or practice model to be tested.For purposes of this funding opportunity, "Tribal courts" are defined consistent with the Bureau of Indian Affairs regulations as "a court with jurisdiction over child custody proceedings and which is either a Court of Indian Offenses, a court established and operated under the code or custom of an Indian tribe, or any other administrative body of a tribe which is vested with authority over child custody proceedings.

The United States Department of Agriculture (USDA) Food and Nutrition Service (FNS) works to end hunger and promote nutrition security. The Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) is a Federal nutrition assistance program that serves pregnant, postpartum, and breastfeeding individuals, infants, and children up to five years old who are income eligible and at nutritional risk. WIC provides nutritious foods, nutrition education including breastfeeding promotion and support, and referrals to health and social services to participants in all 50 geographic states, the District of Columbia, 33 Indian Tribal Organizations (ITOs), and five U.S. territories (American Samoa, Guam, the Commonwealth of the Northern Mariana Islands, Puerto Rico, and the U.S. Virgin Islands). The Consolidated Appropriations Act, 2024 (The Act) (P.L. 117-2) provided the USDA with an appropriation to carry out the WIC Program as authorized by section 17 of the Child Nutrition Act of 1966 (CNA) (42 U.S.C. 1786). ARPA provided the USDA with $390 million to carry out outreach, innovation, and program modernization efforts to increase participation and redemption of benefits in WIC and the WIC Farmers Market Nutrition Program (FMNP). This is an announcement of the availability of funds for a one-time initiative, competitive cooperative agreement for up to four years. Funds are available to an entity (i.e., a civic technology nonprofit or other nonprofit type with similar staffing and experience/expertise; a research institute that is public, private, or nonprofit; or an accredited college or university) that meets the technical requirements outlined in this RFA. USDA anticipates awarding up to $15,000,000 to one selected applicant. The Period of Performance will be at a minimum two Fiscal Years will not exceed a maximum of four Fiscal Years.

Historic battlefields and associated sites of armed conflict are powerful reminders of the shared heritage of all Americans. In an ongoing effort to extend the conservation of natural and cultural resources, the National Park Service American Battlefield Protection Program (NPS ABPP) promotes the preservation and interpretation of these important places. NPS ABPP supports community-driven stewardship of historic resources through four grant opportunities: Preservation Planning, Battlefield Restoration, Battlefield Interpretation, and Battlefield Land Acquisition. NPS ABPP administers the Battlefield Restoration Grant opportunity to provide assistance for the restoration of day-of-battle conditions within eligible Civil War battlefields listed in the Civil War sites Advisory Commission's (CWSAC) Report on the Nation's Civil War Battlefields (1993) and in the principal battlefields of the Revolutionary War and War of 1812 identified in NPS ABPP’s Report to Congress on the Historic Preservation of Revolutionary War and War of 1812 Sites in the United States (2007) (Survey Reports). Restoration sites must be located outside the external boundaries of a unit of the National Park System and must have been protected with assistance from a NPS’s Battlefield Land Acquisition Grant (BLAG) established under 54 U.S.C. §308103(b) or are owned by state or local government entities (e.g., state or local battlefield parks) and are located within the boundaries of battlefields listed in the Survey Reports. These grants are funded from the Land and Water Conservation Fund, which invests earnings from offshore oil and gas leasing to help strengthen communities, preserve history and protect the national endowment of lands and waters. Funding will support planning and implementation activities for historic preservation projects at eligible properties and will be awarded competitively. Grants require a dollar-for-dollar non-Federal match.

The purpose of this NIDCD initiative is to encourage research in the development, characterization, and reproducibility/reliability of human auditory and vestibular organoids. Proposals investigating animal organoids are allowable but only if accompanying comparative or other integrated companion studies with human organoids. Singular animal organoid studies alone are not responsive to this funding opportunity. This funding opportunity encourages innovative, reproducible, and novel methodologies and technologies that will drive the reproducibility and holistic longevity of hearing/balance sensory organoids as model systems. The development of novel tools to deliver genes, proteins, molecules, and synthetics that might lead to the successful expansion and longer-term survivability of organoid populations in a stable, reliable, and reproducible manner is highly encouraged. Subsequent characterization of the organoid platforms must be shown to mimic and recapitulate the native correlative biological function. Applications that provide approaches that remove current barriers and lessen challenges to improve current reproducibility and stability are highly encouraged. Applications that have breakthrough approaches and technologies using human auditory/vestibular organoids are highly encouraged.