Grants for Nonprofits - Federal

This funding opportunity supports researchers in conducting interventional clinical trials aimed at improving health outcomes, providing resources for trial preparation and execution.

This funding opportunity supports researchers conducting feasibility trials of mind and body interventions for high-priority health conditions, aiming to gather essential data for future large-scale clinical studies.

The Inspire! Grants for Small Museums program, administered by the Institute of Museum and Library Services, supports project-based efforts aimed at helping small museums provide museum services to their communities. The program is a special initiative of the Museums for America program, designed specifically for small museums of all disciplines. Projects funded through this program should align with one of the following objectives: supporting lifelong learning through experiential and cross-disciplinary learning experiences, strengthening institutional capacity, or improving collections stewardship and access. Projects must be tied to a key component of the museum’s strategic plan and generate measurable results to address an identified need or challenge. For fiscal year 2025, IMLS anticipates awarding approximately $3,000,000 in funding across 75 grants. The grant program offers two levels of funding: small projects may request between $5,000 and $25,000, with no cost share required, while large projects may request between $25,001 and $75,000, requiring a one-to-one cost share from non-federal sources. Projects must begin on or after September 1, 2025, and can span a performance period of one to three years. Applications are due by November 15, 2024, and must be submitted electronically through Grants.gov by 11:59 p.m. Eastern Time. Eligible applicants include museums that are nonprofit organizations, institutions of higher education, tribal organizations, or units of state or local government located in the United States or its territories. Museums must operate on a permanent basis, have educational or cultural purposes, exhibit objects to the public regularly, and employ professional staff. Museums located within larger parent organizations, such as universities or cultural centers, may apply independently if they operate as discrete units with their own budgets. Partnerships and collaborations with other entities are encouraged to enhance the project’s scope and impact. Applicants are required to submit a complete application, including a project narrative, budget form, budget justification, project schedule, performance measurement plan, strategic plan summary, and organizational profile. The project narrative, limited to five pages, must address three components: project justification, project work plan, and project results. Applicants must clearly identify the primary audience and beneficiaries, outline specific project activities, and explain how outcomes will be sustained after the project concludes. Supporting documents such as resumes, letters of commitment, and conservation reports may also be submitted as applicable. Applications will be evaluated through a peer review process based on the project’s alignment with program goals, clarity and feasibility of the work plan, qualifications of key personnel, and potential for meaningful and lasting results. The peer review criteria focus on the project’s justification, work plan, and intended outcomes, including the applicant’s ability to achieve and measure success. For collections-related projects, improvements in care, condition, or access to collections will also be evaluated. Award notifications are expected in August 2025. Successful applicants will be required to submit interim and final performance and financial reports through IMLS’s grants management system. The program encourages applicants to contact IMLS program officers for guidance during the application process and to participate in informational webinars. Further resources, including sample applications, can be accessed on the IMLS website.

This grant provides funding for individuals and organizations to create programs that strengthen cultural ties between the United States and Armenia, focusing on shared values, education, and community empowerment.

This funding opportunity provides support for researchers conducting early-stage clinical trials focused on innovative interventions for vision disorders that involve greater than minimal risk.

This program provides funding to organizations and individuals in the museum sector to enhance their professional skills and improve museum services.

The ORIP grant supports research projects that aim to improve the validity and reliability of animal research through the development of widely applicable technologies and resources, focusing on studies that impact multiple organ systems or are relevant to various NIH Institutes and Centers.

The U.S. Embassy Kampala / PEPFAR Uganda Small Grants Office announces an open competition for organizations to submit applications for a community grants program to combat HIV/AIDS. Outlined in this announcement are PEPFAR Uganda's funding priorities, the strategic focus themes, and the proposal submission procedures. Please carefully read and follow all instructions below. PEPFAR Uganda invites proposals for projects that do one or more of the following: • Promote HIV/AIDS prevention. • Address stigma, discrimination and/or gender-based violence (GBV). • Promote capacity building of local organizations and community structures to combat HIV. • Strengthen democracy and governance related to the national HIV response. • Promote HIV care and treatment, and continuity of HIV treatment, with a focus on key and priority populations that are disproportionately impacted by HIV.

This funding opportunity provides financial support to various organizations in Wyoming to enhance outdoor recreation access, promote environmental stewardship, and ensure equitable opportunities for underserved communities.

This funding opportunity provides financial support for public diplomacy projects that strengthen U.S.-Slovenian relations and enhance community safety, prosperity, and resilience through initiatives involving both American and Slovenian participants.

This funding opportunity supports nonprofit organizations that provide training for local emergency responders dealing with hazardous materials in rail transportation, ensuring safety and preparedness in their communities.

Nature crimes, criminal forms of logging, mining, wildlife trade, land conversion, and associated criminal activities, as well as crimes associated with fishing, pose serious threats to the environment and to national security. They undermine the rule of law and fuel corruption. They also spread disease globally, drive species to the brink of extinction, and rob governments, indigenous peoples, and local communities of their natural resources and legitimate revenue. The goal of this program is to increase global grassroot civil society engagement in addressing nature crimes. To advance the policy goal described above, OES seeks one or two lead implementing partners to form consortia with grassroots civil society organizations across various countries to deploy community-led approaches that address global nature crime trends. By taking advantage of the valuable knowledge offered by these partners, OES aims to strengthen their efforts to expose nature crimes, hold perpetrators accountable, reduce profits from these crimes, and support the environment and local livelihoods.

This program provides training and support at no cost to small businesses, particularly those that are socially and economically disadvantaged, to help them compete for federal contracts and grow their operations.

This funding opportunity is designed to support academic and community healthcare organizations in enrolling diverse patient populations in cancer clinical trials, enhancing cancer research in underserved areas.

This funding opportunity provides financial and technical support to national nonprofit organizations that will help local community development and housing organizations improve their capacity to deliver affordable housing and community development services, particularly for low- and moderate-income families.

This funding opportunity provides financial support for new and underrepresented researchers in the health sciences to conduct projects aligned with the missions of NIAID or NIDDK.

This Funding Opportunity Announcement (FOA) encourages studies that develop and test the effectiveness of strategies for implementation and sustainable delivery of evidence-based mental health treatments and services to improve mental health outcomes for underserved populations in under-resourced settings in the United States. Studies should identify and use innovative approaches to remediate barriers to provision, receipt, and/or benefit from evidence-based practices (EBPs) and generate new information about factors integral to achieving equity in mental health outcomes for underserved populations. Research generating new information about factors causing/reducing disparities are strongly encouraged, including due consideration of the needs of individuals across the life span.

With this solicitation, OJJDP seeks to provide funding to communities to develop coordinated and comprehensive community-based approaches to help children and their families who are exposed to violence build resilience, restore their safety, heal their social and emotional wounds, and prevent future violence and delinquency. Funding can be used to develop and/or enhance support services for children exposed to violence to reduce the adverse impact of violence on youth, families, and communities, and to help family-serving organizations better recognize and help families at risk for exposure to violence.

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to stimulate translation of scientific discoveries and engineering developments in imaging, data science and/or spectroscopic technologies into methods or tools that address contemporary problems in understanding the fundamental biology, potential risk of development, diagnosis, treatment, and/or disease status for cancer or other disease.

The U.S. Department of State, Bureau of Political-Military Affairs, Office of Weapons Removal and Abatement (PM/WRA) is pleased to invite eligible organizations to submit applications for a cooperative agreement to conduct a physical security and stockpile management program (PSSM) in Somalia during fiscal year 2025. Specific goals, objectives, and technical requirements for application packages are detailed below. PM/WRA anticipates awarding up to $4,000,000 under this funding opportunity.