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Grants for Small businesses - Federal

Explore 1,527 grant opportunities

Interdisciplinary Research Networks to Advance Biomedical Research on Resilience and Health Optimization
$1,500,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

May 25, 2026

Date Added

Sep 24, 2025

This funding opportunity supports interdisciplinary research networks that aim to enhance understanding and capacity for resilience and health optimization in the U.S. population, targeting a wide range of eligible organizations including universities, nonprofits, and government entities.

Health
City or township governments
Rfa-Ot-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Nov 26, 2025

This funding opportunity provides financial support to a wide range of eligible organizations, including state governments, universities, and nonprofits, to enhance public health initiatives focused on injury prevention and community health interventions across the United States.

Health
State governments
Projects In Support Of Naval Aviation
Contact for amount
Naval Air Warfare Center Aircraft Division
Federal

Application Deadline

Jun 22, 2026

Date Added

Jun 26, 2025

This funding opportunity invites a wide range of organizations, including academic institutions and businesses, to propose innovative research and technology projects that enhance naval aviation capabilities for the U.S. Navy.

Science and Technology
Public and State controlled institutions of higher education
Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access (X01 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal
Rolling

Application Deadline

Jul 8, 2026

Date Added

May 26, 2023

This grant provides access to advanced genetic and genomic analysis services for research projects focused on understanding genetic factors in human health and disease, without offering direct funding.

Health
State governments
NSF/CASIS Transport Phenomena Research at the International Space Station to Benefit Life on Earth
$400,000
National Science Foundation
Federal

Application Deadline

Mar 4, 2026

Date Added

Sep 23, 2025

This grant provides funding for U.S.-based researchers and organizations to conduct innovative studies in microgravity that explore transport phenomena, with the goal of developing solutions that benefit life on Earth.

Science and Technology
Public and State controlled institutions of higher education
Global Brain and Nervous System Disorders Research Across the Lifespan - Exploratory Grants
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 24, 2026

Date Added

Sep 27, 2025

This grant provides funding for innovative research on brain and nervous system disorders, encouraging collaboration between U.S. and low- and middle-income country researchers to improve global health outcomes.

Health
City or township governments
BRAIN Initiative: Clinical Studies to Advance Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UH3 Clinical Trial Optional)
$10,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 28, 2026

Date Added

Nov 6, 2024

This funding opportunity supports innovative clinical studies for developing advanced neural devices to treat central nervous system disorders, aimed at higher education institutions, nonprofits, for-profit organizations, and state or local governments in the U.S.

Education
State governments
InteRFAcial Engineering
$3,200,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Apr 5, 2023

This grant provides funding for researchers to explore and develop innovative solutions related to interfacial phenomena and engineering, with a focus on improving chemical and biochemical processes in industry.

Science and Technology
For profit organizations other than small businesses
Broad Agency Announcement For Science, Technology, And Test And Evaluation Research
Contact for amount
U.S. Army Space and Missile Defense Command
Federal

Application Deadline

Aug 26, 2029

Date Added

Mar 18, 2025

This grant invites researchers and organizations to propose innovative scientific studies and experiments that advance technology and knowledge in space and missile defense, without focusing on specific hardware or software development.

Science and Technology
For profit organizations other than small businesses
Energy, Power, Control, and Networks
$4,000,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Jan 3, 2025

This program provides funding for innovative research in advanced control systems, energy integration, and adaptive technologies, targeting researchers and institutions focused on improving energy efficiency, resilience, and decision-making in networked systems.

Science and Technology
For profit organizations other than small businesses
Research Experiences for Undergraduates
$155,000
National Science Foundation
Federal

Application Deadline

Aug 19, 2026

Date Added

Aug 30, 2024

This program provides funding for colleges and universities to engage undergraduate students in hands-on research experiences across various scientific fields, with a focus on supporting those from underrepresented backgrounds and institutions with limited STEM opportunities.

Education
Public and State controlled institutions of higher education
U.S. Army Combat Capabilities Development Command Soldier Center Broad Agency Announcement for Basic and Applied Research
Contact for amount
U.S. Army Combat Capabilities Development Command Soldier Center
Federal
Rolling

Application Deadline

Feb 27, 2030

Date Added

Mar 18, 2025

This funding opportunity is designed to support universities, research institutes, and businesses in developing innovative technologies to enhance soldier performance and address future military challenges.

Science and Technology
Public and State controlled institutions of higher education
Injury Prevention and Control Research and State and Community Based Programs - RFA-PS-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Oct 20, 2023

This funding opportunity provides financial support for state, academic, non-profit, and business organizations to conduct research and implement programs focused on preventing and controlling injuries within communities.

Health
State governments
CHIPS Incentives Program Facilities for Semiconductor Materials and Manufacturing Equipment
Contact for amount
U.S. Department of Commerce (National Institute of Standards and Technology)
Federal

Application Deadline

Nov 1, 2026

Date Added

Oct 17, 2025

This program provides federal funding to private-sector organizations, nonprofits, and consortia for the construction and modernization of facilities that produce semiconductor materials and manufacturing equipment, aiming to strengthen U.S. semiconductor manufacturing and security.

Science and Technology
For profit organizations other than small businesses
Oligonucleotide Toxicity (OligoTox) Open Data Challenge
$500,000
U.S. Department of Health and Human Services (National Center for Advancing Translational Sciences)
Federal

Application Deadline

Feb 28, 2026

Date Added

Dec 24, 2025

This grant encourages researchers and organizations to create and share high-quality datasets that improve the understanding and prediction of toxicity in oligonucleotide therapeutics, particularly using human-based testing methods.

Science and Technology
Nonprofits
Informatics, Coordination and Service Center for the Mutant Mouse Resource and Research Centers (U42 Clinical Trial Not Allowed)
$2,600,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

May 1, 2026

Date Added

Jun 10, 2025

This funding opportunity supports the development and management of a centralized service center that provides genetically engineered mouse models and enhances research coordination, data sharing, and innovative methodologies in biomedical research.

Health
State governments
Continuation or Revision of NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UH3 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 6, 2028

Date Added

Oct 11, 2024

This funding opportunity supports ongoing clinical trials aimed at improving the diagnosis, prevention, and treatment of dental, oral, and craniofacial diseases, encouraging applications from a wide range of eligible institutions and organizations.

Health
State governments
Long Range Broad Agency Announcement (BAA) for NSWC Crane
Contact for amount
U.S. Department of Defense (NSWC CRANE - N00164)
Federal
Rolling

Application Deadline

Not specified

Date Added

Aug 12, 2024

This funding opportunity seeks innovative research proposals from academia, industry, and the research community to advance technologies that support national security in various critical areas, with a focus on collaboration and technical merit.

Science and Technology
For profit organizations other than small businesses
U.S. Army Corps of Engineers Research Grant for Defense and Engineering Innovation
Contact for amount
U.S. Army Corps of Engineers (USACE) Engineer Research and Development Center (ERDC)
Federal
Rolling

Application Deadline

Not specified

Date Added

Mar 18, 2025

This funding opportunity is designed to support innovative prototype projects in military and civil engineering, targeting nontraditional defense contractors, traditional defense contractors, and nonprofit research institutions.

Science and Technology
Public and State controlled institutions of higher education
BJA FY25 Preventing Violence Against Law Enforcement Officers and Ensuring Officer Resilience and Survivability (VALOR) Initiative
$6,000,000
U.S. Department of Justice (Bureau of Justice Assistance)
Federal

Application Deadline

Feb 5, 2026

Date Added

Jan 14, 2026

This funding opportunity provides financial support to law enforcement agencies across the U.S. to enhance officer safety, wellness, and resilience through comprehensive training and resources.

Safety
Nonprofits