Grants for Small Businesses

The purpose of this funding opportunity is to develop artificial intelligence tools and experimental assays to identify new pharmacotherapeutics with lower toxicity and higher efficacy for substance use disorders (SUD) Areas of interest include but are not limited to: 1) Development of AI tools to identify potential target combinations, design new molecules, conduct virtual preclinical studies to predict efficacy and toxicity, and model in vitro and in vivo polypharmacology 2) Development of assays to assess the effects of compounds on multiple targets or functions

This funding opportunity provides support for high-risk clinical trials focused on infectious, immunologic, and allergic diseases, encouraging innovative research that can lead to new treatments and therapies.

This funding opportunity provides financial support for small businesses to conduct innovative clinical trials related to allergy and infectious diseases, focusing on high-risk studies and unlicensed products.

The Idaho Department of Commerce and the Idaho State Department of Agriculture offer the Idaho Online Global Program Awards to support Idaho small businesses in international export marketing initiatives. The program aims to increase the number of small businesses that export, the value of exports, and exploration of new trade opportunities.Overview Individual awards of $9,000 are available for eligible activity occurring between September 30, 2024 – September 29, 2025. Only one application will be accepted per round. Multiple rounds are dependent upon the availability of funds. 20% cash match required. For every authorized $100 you spend you will be reimbursed $80. Reviewing and scoring processes are highly competitive. Watch our overview of the program here. Watch a testimonial from a previous recipient here. Receive a free website and SEO performance report here. Eligible activities for Online Global Program Design and development of website, with an international focus Website translation, search engine optimization (SEO), and localization services Mobile App integration, creation, and updates to support sales Webstore setup and/or maintenance costs Translation of marketing media, including audio and video Set up to receive and/or process online payments and orders Costs associated with selling on platforms such as but not limited to: Amazon Services, Walmart Marketplace, Alibaba Inc., FlipKart, Rakuten Cybersecurity protection to support exports

Name of Funding Organization: Cecil County, Maryland Contact Information: Not provided in the input Grant Program: FY24 Cecil County Route 40 Revitalization Grant Program Intent: The grant aims to assist businesses and organizations located along the Route 40 corridor in Cecil County, Maryland to improve their exterior visual appearance and function. The goal is to enhance the overall visual appearance and increase utilization of these businesses and organizations. Award Details: The maximum award per grant application is $25,000. Grant funds are intended to be used for exterior improvement projects visible from Route 40. Up to 20% of the grant funds may be used for specified interior improvements with prior approval. All funding is contingent upon funding from the State of Maryland and approval of Cecil County Council. Eligibility: Businesses and organizations, both for-profit and non-profit, located within Cecil County along the Route 40 corridor with a Route 40/Pulaski Highway address are eligible to apply. Applicants must be in good standing with the IRS, State of Maryland, and Cecil County. Other Relevant Information: - Applicants must match the funds they are applying for. - Project designs must be approved by Cecil County Government. - Demolition of derelict structures visible from Route 40 will be considered. - Disbursement of grant funding will only be made on a reimbursement basis. - Applications will be accepted on a rolling basis starting January 1, 2024. - Grant funds must be expended by June 30, 2024. Eligible Activities: Signage, Lighting, Roofing, Siding, Painting, Entrance, Porch/Deck, Fencing, Landscaping/Hardscaping, Sidewalks, Driveway, Parking, ADA Ramp, Demolition Ineligible Activities: Improvements to primary residence, Interior renovations, Improvements not visible from Route 40, Trash Removal Project Evaluation: The Grant Review Committee will evaluate applications based on criteria such as completeness, enhanced visual appearance from Route 40, stability of business/organization, positive impact on the business and community, clear explanation of how grant funds will be used, adherence to maximum limit of $25,000, identification of matching funds sources, preference

This program provides financial assistance to small business owners in Texas to help cover costs for training, memberships, and necessary licensing fees to enhance their business operations.

Name of Funding Organization: ViiV Healthcare Grant Program: Positive Action Community Grants (PACG) Program Intent: PACG supports community-led efforts to increase engagement in prevention and care, address stigma, and build trust in HIV care among communities most disproportionately impacted by HIV. Eligibility: Organizations based in the U.S. and Puerto Rico are eligible to apply. Funding Options: Organizations can request funding for general operating support or project support. Application Deadline: The deadline for multiyear proposals is March 8, 2024. Contact Information: For more information, applicants can download the request for proposal from the provided link or access the online grantee portal. All questions and inquiries should be directed to the ViiV Healthcare Help Desk at [email protected].

The United States is made up of regional systems comprising interdependent urban and rural systems and every community category between urban and rural. Urban systems and rural systems are interdependent for the provisioning of food, energy sources, water, other materials and natural resources, markets, manufactured goods, and medical resources. These systems are also connected by ecological processes that both influence and are influenced by human behavior. The vital interconnection of urban-rural systems underscores the critical need for the advancement of sustainable regional systems (SRS). The goal of this solicitation is to fund convergent research and education that will advance sustainable regional systems science, engineering, and education to facilitate the transformation of current regional systems to enhance sustainability. To further the advancement of SRS science, engineering, and education, NSF will support proposals for Sustainable Regional Systems Research Networks (SRS RNs). Sustainable regional systems are connected urban and rural systems that are transforming their structures and processes collaboratively with the goal of measurably and equitably advancing the well-being of people and the planet. The purpose of the SRS RNs competition is to develop and support interdisciplinary, multi-organizational teams working collaboratively to produce cutting-edge convergent research, education, and outreach that addresses grand challenges in sustainable regional systems. SRS RNs will study multiscale regional systems to further SRS science, engineering, and education. Key elements will include new data, methods, and models to understand interactions between natural, human-built, and social systems; improved understanding of interdependencies, mutual benefits, and trade-offs of different wellbeing outcomes for humans and the environment; new and generalizable theories of change relevant to SRS;theco-production of knowledge; andexploration of conceptsof social equity in sustainable regional systems across spatial and temporal scales. SRS RN outcomes will have the potential to inform societal actions for sustainability across urban systems and the connected rural communities that make up regional systems. Subject to availability of funds and quality of proposals, this SRS RN solicitation will support: SRS RN Awards.These awards will supportfundamental convergent research, education, and outreach that addressesengineering, chemistry, biology, geosciences, mathematics, statistics, environmental, data, computational, education, and social, behavioral, and economic sciences ofsustainable regional systems in partnerships thatmay embrace universities, colleges, federal, state, and local governments, tribal communities, non-governmental and international bodies, non-profit organizations, industry, practitioners, and other community groups. The award size is up to $15 million totalwith a duration of 5 years. SRS RNs will conduct innovative and pioneering fundamental research and education that is of a scale and complexity that would not be possible within a single organization, center, or through the normal collaborative modes of NSF research support in core programs.

The City of York's Education, Empowerment & Enhancement (3E) Grant Program is supported by ARPA funds and aims to increase the operating capacity of small businesses. This program is rooted in the city's broader ARPA grant initiatives, which are designed to benefit City of York residents and the community. The alignment with the city's mission is evident in its focus on supporting local businesses, particularly those in Qualified Census Tract (QCT) areas, which the U.S. Treasury recognizes as disproportionately impacted. This strategic focus ensures that grant funds are directed towards areas and populations most in need, contributing to the overall economic resilience and social well-being of the city. The primary target beneficiaries of the 3E Grant Program are small business owners in the City of York who are minorities, women, or people with disabilities. To be eligible, businesses must also earn $500,000 or less in annual gross revenues, be registered, licensed, and in good standing on all City taxes and obligations, and be physically located within a QCT in the City of York. Additionally, no owners should have been convicted of financial crimes within the past three years. The program's impact goals are centered on fostering business growth and stability within these underserved communities by providing resources for education, professional development, and operational enhancements. The program's priorities and focuses are clearly outlined by the "3E's": Education, Empowerment, and Enhancement. Education encompasses classes, certificates, and training for business owners and/or their employees. Empowerment focuses on retreats, workshops, and coaching to build professional development. Enhancement involves improvements to business operations through new software, products, or equipment. These areas represent the core strategies through which the grant intends to address the operational capacity and growth challenges faced by eligible small businesses. Expected outcomes include a measurable increase in the operating capacity of participating small businesses. This can manifest as improved skills through education, enhanced leadership and strategic thinking through empowerment, and increased efficiency or service offerings through operational enhancements. Eligible costs must occur within a year of receiving grant funds, providing a clear timeframe for impact. The program's theory of change posits that by investing in these key areas, the City of York can create a more equitable and robust local economy, particularly for businesses in historically disadvantaged areas, leading to sustained growth and community benefit.

This funding opportunity supports researchers exploring the mechanisms and effects of trained immunity in the immune system, particularly its implications for infectious diseases and immune-related conditions.

This funding opportunity supports research projects that explore the basic mechanisms and effects of trained immunity in the innate immune system, targeting a wide range of institutions and researchers interested in immune responses and related diseases.

This initiative provides financial assistance to small businesses in San Francisco that have experienced vandalism, helping them cover repair costs and maintain their storefronts.

This program provides financial support to new and existing child care businesses in Portland, Maine, to help them start, expand, and hire staff, ensuring more accessible child care options in the community.

This program provides $5,000 grants to small businesses and non-profits in Norco, California, that have been financially impacted by the COVID-19 pandemic.

This funding opportunity provides financial support to small U.S.-based businesses for the development and validation of analytical methods to measure biomarkers related to neurological and neuromuscular disorders, with an emphasis on enhancing inclusivity and collaboration in research.

Scientific observations, experiments, and simulations are producing data at rates beyond our capacity to store, analyze, stream, and archive the data in raw form. Of necessity, many research groups have already begun reducing the size of their data sets via techniques such as compression, reduced order models, experiment-specific triggers, filtering, and feature extraction. Once reduced in size, transporting, storing, and analyzing the data is still a considerable challenge a reality that motivates SCs Integrated Research Infrastructure (IRI) program [1] and necessitates further innovation in data-reduction methods. These further efforts should continue to increase the level of mathematical rigor in scientific data reduction to ensure that scientifically-relevant constraints on quantities of interest are satisfied, that methods can be integrated into scientific workflows, and that methods are implemented in a manner that inspires trust that the desired information is preserved. Moreover, as the scientific community continues to drive innovation in artificial intelligence (AI), important opportunities to apply AI methods to the challenges of scientific data reduction and apply data-reduction techniques to enable scientific AI, continue to present themselves [2-4].The drivers for data reduction techniques constitute a broad and diverse set of scientific disciplines that cover every aspect of the DOE scientific mission. An incomplete list includes light sources, accelerators, radio astronomy, cosmology, fusion, climate, materials, combustion, the power grid, and genomics, all of which have either observatories, experimental facilities, or simulation needs that produce unwieldy amounts of raw data. ASCR is interested in algorithms, techniques, and workflows that can reduce the volume of such data, and that have the potential to be broadly applied to more than one application. Applicants who submit a pre-application that focuses on a single science application may be discouraged from submitting a full proposal.Accordingly, a virtual DOE workshop entitled Data Reduction for Science was held in January of 2021, resulting in a brochure [5] detailing four priority research directions (PRDs) identified during the workshop. These PRDs are (1) effective algorithms and tools that can be trusted by scientists for accuracy and efficiency, (2) progressive reduction algorithms that enable data to be prioritized for efficient streaming, (3) algorithms which can preserve information in features and quantities of interest with quantified uncertainty, and (4) mapping techniques to new architectures and use cases. For additional background, see [6-9].The principal focus of this FOA is to support applied mathematics and computer science approaches that address one or more of the identified PRDs. Research proposed may involve methods primarily applicable to high-performance computing, to scientific edge computing, or anywhere scientific data must be collected or processed. Significant innovations will be required in the development of effective paradigms and approaches for realizing the full potential of data reduction for science. Proposed research should not focus only on particular data sets from specific applications, but rather on creating the body of knowledge and understanding that will inform future scientific advances. Consequently, the funding from this FOA is not intended to incrementally extend current research in the area of the proposed project. Rather, the proposed projects must reflect viable strategies toward the potential solution of challenging problems in data reduction for science. It is expected that the proposed projects will significantly benefit from the exploration of innovative ideas or from the development of unconventional approaches. Proposed approaches may include innovative research with one or more key characteristics, such as compression, reduced order models, experiment-specific triggers, filtering, and feature extraction, and may focus on cross-cutting concepts such as artificial intelligence or trust. Preference may be given to pre-applications that include reduction estimates for at least two science applications.

The United States Agency for International Development Mission in Indonesia (USAID/Indonesia) posts this Request for Information (RFI) to inform interested parties of an upcoming health system strengthening (HSS) activity designed to improve accountability, health system performance and health outcomes (especially for Maternal and Child Health, Tuberculosis, HIV, and Global Health Security) based on performance-based and sustainable health financing, a strengthened health information system, resilient human resources for health, integrated care models, and a strong evidence to policy pathway.This Request for Information (RFI) is issued solely for information gathering purposes and is published in accordance with FAR Part 10 and FAR Part 15.201(e).Through this RFI, USAID/Indonesia seeks to enhance the design of the HSS Flagship Activity in Indonesia. This RFI seeks information from capable organizations (i.e., nongovernmental organizations, universities, consortium, for-profit, and local organizations) that are implementing or have implemented HSS projects that spans more than one health system building block and may be interested to partner with USAID in achieving the goals of this future HSS activity. All capable organizations are encouraged to respond.This RFI does not constitute a Request for Applications (RFA) or a Request for Proposals(RFP). Responses to this RFI are not applications or official proposals and will in no way be deemed to form any binding agreement with the RFI issuing authority. Please do not submit applications, proposals, budget, costs, resumes or promotional materials, as they will be discarded. Proprietary information should not be sent. USAID may use any information provided without incurring any obligation. USAID reserves the right to, or not to incorporate any, some, or none of the comments received from this RFI into any subsequent solicitations or design documents.(See further information in Related Documents Tab)

This Notice of Funding Opportunity (NOFO) invites applications from eligible small businesses to develop solutions for commercialization that can be used to enable regional clinician-to-clinician genomic medicine eConsult services. Specifically, we seek products, such as technologies or services, that will allow for the development and sustainment of eConsult services. Eligible United States small business concerns (SBCs) may submit Small Business Technology Transfer (STTR) Phase I, and Fast-Track grant applications. Small business applicants interested in submitting a Small Business Innovation Research (SBIR) grant application should submit to the related funding opportunity, PAR-24-106. SBIR and STTR are phased programs. The main objective in SBIR and STTR Phase I is to establish the technical merit and feasibility of the proposed research and development efforts. An SBIR and STTR Phase II continues the R&D efforts to advance the technology toward ultimate commercialization. At the conclusion of an SBIR/STTR Phase II, it is expected that the small business will fully commercialize their product or technology using non-SBIR/STTR funds (either federal or non-federal). Small businesses that are eligible to submit Phase II applications for projects that were supported with a Phase I SBIR or STTR award are expected to submit the regular Phase II application as a "Renewal" application based on the awarded Phase I SBIR or STTR project. Only one Phase II application may be awarded for a specific project supported by a Phase I award.

This Notice of Funding Opportunity (NOFO) invites applications from eligible small businesses to develop solutions for commercialization that can be used to enable regional clinician-to-clinician genomic medicine eConsult services. Specifically, we seek products, such as technologies or services, that will allow for the development and sustainment of eConsult services. Eligible United States small business concerns (SBCs) may submit Small Business Innovation Research (SBIR) Phase I, Direct to Phase II, and Fast-Track grant applications. Small business applicants interested in submitting a Small Business Technology Transfer (STTR) grant application should submit to the related funding opportunity, PAR-24-107. SBIR and STTR are phased programs. The main objective in SBIR and STTR Phase I is to establish the technical merit and feasibility of the proposed research and development efforts. An SBIR and STTR Phase II continues the R&D efforts to advance the technology toward ultimate commercialization. At the conclusion of an SBIR/STTR Phase II, it is expected that the small business will fully commercialize their product or technology using non-SBIR/STTR funds (either federal or non-federal). Small businesses that are eligible to submit Phase II applications for projects that were supported with a Phase I SBIR or STTR award are expected to submit the regular Phase II application as a "Renewal" application based on the awarded Phase I SBIR or STTR project. Only one Phase II application may be awarded for a specific project supported by a Phase I award. NIH Fast-Track: An NIH SBIR Fast-Track incorporates a submission and review process in which both Phase I and Phase II applications are submitted and reviewed together as one application to reduce or eliminate the funding gap between phases. NIH Direct to Phase II: For small businesses that have already demonstrated scientific and technical merit and feasibility but have not received a Phase I SBIR or STTR for that project, NIH can issue a Direct to Phase II award. The NIH will accept Direct to Phase II applications regardless of the funding source for the proof of principle work on which the proposed Phase II research is based. Direct to Phase II awards should be submitted as “New” applications and not continuations ("Renewal") of Phase I SBIR or STTR projects.

This Notice of Funding Opportunity (NOFO) invites applications for the continued support and advancement of the Mutant Mouse Resource and Research Centers (MMRRC). The MMRRC consortium is expected to facilitate research by identifying, acquiring, evaluating, characterizing, cryopreserving, and distributing mutant mouse strains to qualified biomedical investigators. A regional network of four MMRRCs and an Informatics, Coordination and Service Center (ICSC) collectively serve the needs of the biomedical research community for transgenic, knockout and other genetically-engineered mutant mice and related biomaterials. MMRRC strains are held to the highest standards to optimize reproducibility of studies and assure scientific rigor and transparency; all submitted strains are thoroughly reviewed and documented and include additional quality control measures. The Program Director/Principal Investigator (PD/PI) of each MMRRC in addition to the major resource activities is required to develop a small high risk, high return, research pilot project that complements the goals and needs of the MMRRC consortium. ORIP intends to fund up to four awards, but the overall number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications Award Budget Requested Direct Costs must reflect actual needs of the project. For Renewal (a.k.a. Type 2) applications, no more than a 5 percent (direct cost) increase from the last non-competing year will be accepted. ORIP intends to fund up to four awards, but the overall number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications